• Title/Summary/Keyword: Reduction Potential

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Protective Effect of Rhus Semialata M. extract on Epidermal Stem Cells against UV Irradiation (자외선 조사된 상피 줄기세포에 대한 붉나무 추출물의 보호 효과)

  • Woo, Hyunjoo;You, Jiyoung;Park, Deokhoon;Jung, Eunsun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.4
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    • pp.415-422
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    • 2019
  • Human epidermal stem cells(ESCs) residing in the basement membrane of the skin have an important role in maintenance of skin homeostasis of epidermal layer. Although, ESCs provide new cells to repair damaged tissue in response to tissue injury, subsets of stem cells remain in the quiescent state protected from differentiation and senescence for prolonged survivals. In this perspective, the stem cell niche, which is specific microenvironment composed of niche cells and an extracellular matrix(ECM), supplies the relevant signal to save stem cells from microenvironmental damages. The expression of stemness marker on the surface of ESCs contributes to the attachment on their ECM of the basement membrane, which lead to growth potential and apoptotic resistance against environmental stimuli. In this study, we observed that UV irradiation, a major factor of environmental stimuli, reduced the expression of α2, β1 and α6 integrin in ESCs. Rhus Semialata M extract(RSE) showed inhibitory effect on the UVB-induced reduction of integrin expression. Furthermore, RSE could upregulate the expression of Col-IV and Laminin, which contribute to the attachment of ESCs. These results indicated that RSE could be a potent ingredient for the protection of ESCs from UV irradiation by increasing the expression of integrin and substrate ECM components at their niche.

Prospects for Worldwide CBM(Coalbed Methane) Development (세계 석탄층메탄가스(CBM) 개발전망)

  • Kim, Young-In
    • Economic and Environmental Geology
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    • v.48 no.1
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    • pp.65-75
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    • 2015
  • The CBM(Coalbed Methane) development technology being developed in mid 1980s is the technology to produce the methane gas absorbed in the coal bed. CBM is easy to be developed and its coal deposit is abundant. Therefore, the CBM industry has a large potential as an energy source as well as to deal with the global regulations for reducing greenhouse gas emission. In order to produce coal, the CBM should first be developed as a preliminary action for mine security. So CBM is advantageous in reducing the global greenhouse gas as well as its advantage not being influenced by the changes in gas market. The ECBM (Enhanced Coalbed Methane) is a new technique producing the methane gas which is substituted and disorbed from coal by injecting $CO_2$ or $N_2$ gas into a coal bed. Especially, $CO_2$-ECMB is a low-carbon, green-growth technology, so can expect to the effect of green gas reduction as well as the improved productivity of methane gas. CBM technology is being developed in about 40 nations including Canada, Australia, China, India, Indonesia and Viet Nam, and the coal output using this technology is continually being increased. The CBM is expected to contribute in changing the energy source paradigm from current coal & petroleum energy to unconventional gas.

Metabolic Engineering of the Brassinosteroid Biosynthetic Pathways (Brassinosteroid의 대사공학)

  • Lee, Mi-Ock;Song, Ki-Hong;Lee, Hyun-Kyung;Jung, Ji-Yoon;Choe, Vit-Nary;Choe, Sung-Hwa
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2002.04b
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    • pp.69-75
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    • 2002
  • Sterols play two major roles in plants: a bulk component in biological membranes and precursors of plant steroid hormones. Physiological effects of plant steroids, brassinosteroids (BRs), include cell elongation, cell division, stress tolerance, and senescence acceleration. Arabidopsis mutants that carry genetic defects in BR biosynthesis or its signaling display characteristic phenotypes, such as short robust inflorescences, dark-green round leaves, and sterility. Currently there are more than 100 dwarf mutants representing 7 genetic loci in Arabidopsis. Mutants of 6 loci, dwf1/dim1/cbb1, cpd/dwf3, dwf4, dwf5, det2/dwf6, dwf7 are rescued by exogenous application of BRs, whereas bri1/dwf2 shares phenotypes with the above 6 loci but are resistant to BRs. These suggest that the 6 loci are defective in BR biosynthesis, and the one locus is in BR signaling. Biochemical analyses, such as intermediate feeding tests, examining the levels of endogenous BR, and molecular cloning of the genes revealed that dwf7, dwf5, and dwf1 are defective in the three consecutive steps of sterol biosynthesis, from episterol to campesterol via 5-dehydroepisterol. Similarly, det2/dwf6, dwf4, and cpd/dwf3 were Shown to be blocked in $D^4$ reduction, 22a-hydroxylation, and 23 a-hydroxylation, respectively. A signaling mutant bri1/dwf2 carries mutations in a Leucine-rich repeat receptor kinase. Interestingly, the bri1 mutant was shown to accumulate significant amount of BRs, suggesting that signaling and biosynthesis are dynamically coupled in Arabidopsis. Thus it is likely that transgenic plants over-expressing the rate-limiting step enzyme DWF4 as well as blocking its use by BRI1 could dramatically increase the biosynthetic yield of BRs. When applied industrially, BRs will boost new sector of plant biotechnology because of its potential use as a precursor of human steroid hormones, a novel lead compound for cholesterol-lowering effects, and a various application in plant protection.

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Weed Control Technology with Low Concentration Ethanol in Protected Cereal Crop Cultivation (비닐하우스 내 조 재배시 저농도 에탄올을 이용한 잡초억제 효과)

  • Hwang, Jae-Bok;Yun, Eul-Soo;Park, Chang-Young;Jung, Ki-Youl;Choi, Young-Dae;Jeon, Sung-Ho;Lee, Yong-Hwan
    • Korean Journal of Weed Science
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    • v.32 no.2
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    • pp.115-120
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    • 2012
  • Weed control is of fundamental importance when planting cereal crops, particularly during the establishment phase. Weeds compete for nutrients, water and light, and can severely threaten the survival and early growth of newly planted crops. Field experiment was conducted to evaluate the effect of ethanol treatment on the weed control efficacy in cereal crops in protected vinylhouse. Five treatments like water, 25 L, 50 L, 75 L, and 100 L per $m^{-2}$ at 2% ethanol were applied and covered with vinyl on 10 days before foxtail millet seeding. After that, foxtail millet seeds were sown on June 20 at $60{\times}10cm$ planting distance and weed control efficacy was recorded at 30, and 50 days after seeding based on the dry weight. Soil oxidation-reduction potential was recorded -200~-400 mV after treatment 2 days. Weed control efficacy of at 75 L, and 100 L per $m^{-2}$ was observed 92%, 84% in 2% ETOH, respectively. Yields of foxtail millet at 75 L, and 100 L per $m^{-2}$ were 1,570 kg $ha^{-1}$, 1,230 kg $ha^{-1}$, respectively.

Sterilizing Effect of Electron Beam on Ginseng Powders (Electron Beam 조사에 의한 인삼분말의 살균효과)

  • Lee, Mi-Kyung;Lee, Moo-Ha;Kwon, Joong-Ho
    • Korean Journal of Food Science and Technology
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    • v.30 no.6
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    • pp.1362-1366
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    • 1998
  • The sterilizing effect of electron beam was compared with that of gamma irradiation for commercial ginseng powders. White and red ginseng powders were contaminated by about $10^5\;CFU/g$ of total bacteria and by $10^3\;CFU$ of coliforms only in white ginseng powder. Data of microbial population for the sterilizing effect of electron beam irradiation showed that no microorganisms were detected in the samples irradiated up to 7.5 kGy for total aerobic bacteria and 2.5 kGy for molds and coliforms. Such doses were effective for controlling the microbial growth in the samples during 4 months of storage at room temperature. Decimal reduction doses $(D_{10}$ value) on the initial bacterial populations were $2.85{\sim}3.75\;kGy$ in electron beam and $2.33{\sim}2.44\;kGy$ in gamma irradiation, which were influenced by the initial microbial loads and the energy applied. Compared with gamma irradiation, electron beam showed a similar result in its sterilizing effect on ginseng powders, suggesting its potential utilization in due time.

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A Demand forecasting for Electric vehicles using Choice Based Multigeneration Diffusion Model (선택기반 다세대 확산모형을 이용한 전기자동차 수요예측 방법론 개발)

  • Chae, Ah-Rom;Kim, Won-Kyu;Kim, Sung-Hyun;Kim, Byung-Jong
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.10 no.5
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    • pp.113-123
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    • 2011
  • Recently, the global warming problem has arised around world, many nations has set up a various regulations for decreasing $CO_2$. In particular, $CO_2$ emissions reduction effect is very powerful in transport part, so there is a rising interest about development of green car, or electric vehicle in auto industry. For this reason, it is important to make a strategy for charging infra and forcast electric power demand, but it hasn't introduced about demand forecasting electric vehicle. Thus, this paper presents a demand forecasting for electric vehicles using choice based multigeneration diffusion model. In this paper, it estimates innovation coefficient, immitation coefficient in Bass model by using hybrid car market data and forecast electric vehicle market by year using potential demand market through SP(Stated Preference) experiment. Also, It facilitates more accurate demand forecasting electric vehicle market refelcting multigeneration diffusion model in accordance with attribute progress in development of electric vehicle. Through demand forecasting methodology in this paper, it can be utilized power supply and building a charging infra in the future.

Crystal growth studies of $SF_6$ clathrate hydrate ($SF_6$ 하이드레이트 결정의 성장 특성에 대한 연구)

  • Lee, Yoon-Seok;Lee, Ju-Dong;Lee, Bo-Ram;Lee, Hyun-Ju;Lee, Eun-Kyung;Kim, Soo-Min;Kim, Young-Seok;Yoon, Seog-Young;Kim, Yang-Do
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.19 no.5
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    • pp.228-236
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    • 2009
  • In this study, we investigated morphological characteristics of $SF_6$ clathrate hydrate crystals to understand its formation and growth mechanism. $SF_6$ clathrate hydrate crystals were formed in high-pressure reaction cell charged with pure water and $SF_6$ gas at constant pressure and temperature. Two-phase ($SF_6$ gas/aqueous solution) and three-phase ($SF_6$ gas/aqueous solution/$SF_6$ liquid) conditions were investigated, In both conditions, dendritic shape hydrate crystals were grown as like fibriform crystals along upward growth direction at the gas/aqueous solution interface. In the case of the reaction process of three-phase condition, when the $SF_6$ gas bubbles which were generated in $SF_6$ liquid phase due to the reduction of reaction cell pressure stuck to the gas/aqueous interfaces, the hydrate phase were appeared at the surface of the bubbles. This paper presents the detail growth characteristics of $SF_6$ hydrate crystals including crystal nucleation, migration, growth and interference.

Evaluation of Field Nonlinear Modulus of Subgrnde Soils Using Repetitive Static Plate Bearing Load Test (반복식 평판재하시험을 이용한 노상토의 현장 변형계수 평가)

  • Kim Dong-Soo;Seo Won-Seok;Kweon Gi-Chul
    • Journal of the Korean Geotechnical Society
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    • v.21 no.6
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    • pp.67-79
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    • 2005
  • The field plate load test has a good potential for determining modulus since it measures both plate pressure and settlement. Conventionally the modulus has been assumed to be a constant secant value defined from the settlement of the plate at a given load intensity. A constant modulus (modulus of subgrade reaction, k), however, may not be a representative value of subgrade soil under working load. Field strain(o. stress)-dependent modulus characteristics of subgrade soils, at relatively low to intermediate strains, are important in the pavement design. In this study, the field strain dependent moduli of subgrade soils were obtained using cyclic plate load test. Testing procedure and data reduction method are proposed. The field crosshole and laboratory resonant column tests were also performed to determine field nonlinear modulus at $0.001\%\;to\;0.1\%$ strains, and the modulus values and nonlinear trends are compared to those obtained by cyclic plate load tests. Both modulus values match relatively well when the different state of stress between two tests was considered, and the applicability of field cyclic plate load test for determining nonlinear modulus values of subgrade soils is verified.

Radiolysis of Paraffin Encapsulation Wax (파라핀 고화체의 방사선적 가수분해)

  • Kim, Chang-Lak;Lee, Myung-Chan;Park, Won-Jae;Suk, Tae-Won;Burns William G.
    • Journal of Radiation Protection and Research
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    • v.20 no.4
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    • pp.237-243
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    • 1995
  • An estimate is made on the potential generation rate of H: from radiolysis of the Paraffin-wax encapsulant Proposed for the solidified liquid concentrate wasteform. The results show that the radiolytic Production of $H_2$ from paraffin-wax-encapsulated waste is dominated by the radiation energy released from $^{60}Co$. The radiolytic production of $H_2$ will proceed at an initial rate equivalent to aproximately $4.4{\times}10^2cm^3yr^1$ in 200 litre drums that are partly filled with 120 litres of encapsulated waste. The gas production rate will fall to a value of $7.2cm^3yr^1$ after 100 years. The lower flammable limit for $H_2$ in air will be reached in about 25 years and the lower explosive limit for $H_2$ in air would not be reached in 1000years. The timescale in which these safety-related limits are reached is strongly dependent on the level of filling of each waste drum. A reduction of the air space inside each drum would reduce the time required to reach the lower flammable limit.

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Effect of γ-Aminobutyric Acid (GABA) Producing Bacteria on In vitro Rumen Fermentation, Biogenic Amine Production and Anti-oxidation Using Corn Meal as Substrate

  • Ku, Bum Seung;Mamuad, Lovelia L.;Kim, Seon-Ho;Jeong, Chang Dae;Soriano, Alvin P.;Lee, Ho-Il;Nam, Ki-Chang;Ha, Jong K.;Lee, Sang Suk
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.6
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    • pp.804-811
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    • 2013
  • The effects and significance of ${\gamma}$-amino butyric acid (GABA) producing bacteria (GPB) on in vitro rumen fermentation and reduction of biogenic amines (histamine, methylamine, ethylamine, and tyramine) using corn meal as a substrate were determined. Ruminal samples collected from ruminally fistulated Holstein cows served as inoculum and corn was used as substrate at 2% dry matter (DM). Different inclusion rates of GPB and GABA were evaluated. After incubation, addition of GPB had no significant effect on in vitro fermentation pH and total gas production, but significantly increased the ammonia nitrogen ($NH_3$-N) concentration and reduced the total biogenic amines production (p<0.05). Furthermore, antioxidation activity was improved as indicated by the significantly higher concentration of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) among treated samples when compared to the control (p<0.05). Additionally, 0.2% GPB was established as the optimum inclusion level. Taken together, these results suggest the potential of utilizing GPB as feed additives to improve growth performance in ruminants by reducing biogenic amines and increasing anti-oxidation.