• Nutrition Research and Practice
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• v.16 no.1
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• pp.60-73
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• 2022

BACKGROUND/OBJECTIVES: The extract from Dendropanax morbifera exhibited diverse therapeutic potentials. We aimed to evaluate the efficacy and safety of D. morbifera leaf extract for improving metabolic parameters in human. SUBJECTS/METHODS: A 12-week, double blind, placebo-controlled and randomized trial included a total of 74 adults, and they were assigned to the placebo group (n = 38) or 700 mg/day of D. morbifera group (n = 36). The efficacy endpoints were changes in glycemic, lipid, obesity, and blood pressure (BP) parameters, in addition to the prevalence of metabolic syndrome (MetS) and the numbers of MetS components. Safety was assessed by monitoring adverse events (AEs). RESULTS: After 12 weeks of treatment, the hemoglobin A1c (HbA1c) level significantly decreased in the D. morbifera group compared to that of the placebo group (difference: -0.13 ± 0.20% vs. 0.00 ± 0.28%, P = 0.031; % of change: -2.27 ± 3.63% vs. 0.10 ± 5.10%, P = 0.025). The homeostatic model assessment for insulin resistance level also decreased significantly from its baseline in the D. morbifera group. The systolic BP of D. morbifera group decreased significantly than that of placebo group (difference: -3.9 ± 9.8 mmHg vs. 3.3 ± 11.7 mmHg, P = 0.005; % of change: -2.8 ± 7.7% vs. 3.3 ± 10.2%, P = 0.005). However, the lipid parameters and body composition including body weight did not differ between the groups. The prevalence of MetS (36.8% vs. 13.9%, P = 0.022) and the incidence of MetS (10.5% vs. 13.9%, P = 0.027) at 12 weeks was significantly lower in the D. morbifera group than it was in the placebo group. No serious AEs occurred in either group. CONCLUSIONS: Supplementation with D. morbifera extracts over a 12-week period improved metabolic parameters such as HbA1c and BP and reduced the prevalence of MetS.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.5
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• pp.127-134
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• 2022

In this study, RCPTs (Rapid Chloride Penetration Test) were performed for fly ash concrete with curing age of 4 ~ 6 years. The concrete mixtures were prepared with 3 levels of water to binder ratio (0.37, 0.42, and 0.47) and 2 levels of substitution ratio of fly ash (0 and 30%), and the improved passed charges of chloride ion behavior were quantitatively analyzed. Additionally, the results were trained through the univariate time series models consisted of GRU (Gated Recurrent Unit) algorithm and those from the models were evaluated. As the result of the RCPT, fly ash concrete showed the reduced passed charges with period and an more improved resistance to chloride penetration than OPC concrete. At the final evaluation period (6 years), fly ash concrete showed 'Very low' grade in all W/B (water to binder) ratio, however OPC concrete showed 'Moderate' grade in the condition with the highest W/B ratio (0.47). The adopted algorithm of GRU for this study can analyze time series data and has the advantage like operation efficiency. The deep learning model with 4 hidden layers was designed, and it provided a reasonable prediction results of passed charge. The deep learning model from this study has a limitation of single consideration of a univariate time series characteristic, but it is in the developing process of providing various characteristics of concrete like strength and diffusion coefficient through additional studies.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.6
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• pp.787-792
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• 2022

In winter, the excessive use of deicing salt deteriorates concrete pavement durability. To reduce the amount of deicing salt used, phase-change materials (PCMs) potentially offer an alternative way to melt snow through their latent heat storage characteristics. In this research, thermal energy storage concrete was developed by using PCM-impregnated expanded clay as 50 % replacement to normal aggregate by volume. In addition, to improve the thermal efficiency of PCM lightweight aggregate (PCM-LWA)-incorporated concrete, multi-walled carbon nanotubes (MWCNTs) were incorporated in proportions of 0.10 %, 0.15 %, and 0.20 % by binder weight. Compressive strength testing and programmed thermal cycling were performed to evaluate the mechanical and thermal responses of the PCM-LWA concrete. Results showed a significant strength reduction of 54 % due to the PCM-LWA; however, the thermal performance of the PCM-LWA concrete was greatly improved with the addition of MWCNTs. Thermal test results showed that 0.10 % MWCNT-incorporated concrete had high thermal fatigue resistance as well as uniform heat flow, whereas specimens with 0.15 % and 0.20 % MWCNT content had a reduced thermal response due to supercooling when the ambient temperature was varied between -5℃ and 10℃.

• Composites Research
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• v.35 no.6
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• pp.447-455
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• 2022

Currently, the problem of pollution of the marine environment by microplastics is emerging seriously internationally. In this study, to develop a lightweight portable microplastic collection device, the types and number of microplastics in 21 coastal areas nationwide in Korea were investigated. And CFRP (Carbon Fiber Reinforced Plastic), GFRP (Glass Fiber Reinforced Plastic), ABS (Acrylonitrile Butadiene Styrene copolymer) and aluminum were applied for design and analysis of microplastic collection device to have the durability, corrosion resistance and lightweight. As a result of sample collection and classification from the shore, it was confirmed that microplastics were distributed the most in Hamdeok beach, and the polystyrene was found to be mainly distributed microplastics. Particle information through coastal field survey and CFD (Computational Fluid Dynamics) analysis were used to analyze the flow rate and distribution of particles such as sand and impurities, which were applied to the structural analysis of the cyclone device using the finite element method. As a result of structural analysis considering the particle impact inside the cyclone device, the structural safety was examined as remarkable in the order of CFRP, GFRP, aluminum, and ABS. In the view of weight reduction, CFRP could be reduced in weight by 53%, GFRP by 47%, and ABS by 61% compared to aluminum for the cyclone device.

• Journal of Korean Society of Disaster and Security
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• v.15 no.3
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• pp.67-77
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• 2022

In South Korea, U-type girder development was attempted as a means to increase the length of I-type girder, but due to the large self-weight according to the post-tension method, the application of rail bridges of 30m or less is typical. There are not many examples of application of pre-tension type girder. This study does not limit the post-tension method, but applies the pre-tension method to induce a reduction in self-weight and materials used due to the reduction of the cross-section. In addition, we intend to apply the on-site pre-tensioning method using the internal reaction arm of the U-type girder. The prestressed concrete U-type girder bridge is composed of a concrete deck slab and a composite section. Compared to the PSC I-type, which is an open cross-section because the cross section is closed, structural performance such as resistance and rigidity is improved, the safety of construction is increased during the manufacturing and erection stage, and the height ratio is reduced due to the reduction of its own weight. Therefore, it is possible to secure the aesthetic scenery and economical of the bridge. As a result, it is expected that efficient construction will be possible with high-quality factory-manufactured members and cast-in-place members. In this paper, the introduction of the pre-tension method on-site and the analytical performance verification of the anchoring block for tension are included.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.28 no.1
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• pp.81-88
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• 1983

This experiment was conducted to study about influenced inorganic element contents of flag leaf and chaff with different nitrogen and silicate application in Jinan (sea level 303m). The recommended rate of fertilizer application above N 15kg/10a was poor for dry production increment in cold in July elevation and was demanded increment of silicate. In the elevation of cold in July high rates of nitrogen application produced more incomplete grain and a reduced cold tolerance. These effects were due to over-content of soluble nitrogen within flag leaf and disturbance of uptaking potassium and silicate. On the other hand, the application of silicate could increase yield by promoting resistance to cold- damage. The application of increasing level of nitrogen resulted in increasing the contents of total nitrogen and phosphate in both sterile and fertile glumes. The contents of potassium and calcium were the highest at the level of nitrogen 10 - 15kg/10a, but magnessium was rather high at low nitrogen levels. It is interesting that at any level of nitrogen, over 6% higher silicate contents were noted in the fertile chaff than in the sterile chaff. Application of increasing level of silicate fertilizer decreased total nitrogen contents, but increased the contents of phosphate, potassium. and silicate in the chaff. Increasing rate of silicate content by increasing silicate addition was remarkably higher in the fertile chaff than in the sterile chaff.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.253-259
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• 2019

Prostate cancer(PrCa) is a leading cause of cancer-related death in man. Medicinal plants are exploited for many drugs to treat various ailments. The drugs derived from the plants promote health, augmented the resistance of the body against disease. Pueraia lobata(wild) Ohwi(P. Lobata), kudzu, which is a twining perennial woody herb native to China, Korea, Japan, India, and the United States. Plants such as Moringa oleifera, have hypoglycemic properties and other beneficial properties. The objective of the study was to analyze the effects of kadzu and moringa, natural plant products on antioxidant activity and proliferation of the hormone-sensitive prostate cancer LNCaP cells. MTT assay, flow cytometry analysis were employed to investigate the anticancer mechanism and DPPH assay was determined to the antioxidant activity to scavenge free radicals in extract of these. All two extracts showed significantly antioxidant activity at 10 and 50mg/ml of concentration. kadzu and moringa reduced LNCaP cell viability in a dose dependent manner. Specially moringa extract was more potent cytotoxic than kadzu extract. Statistical analyses revealed kadzu and moringa exhibited significantly higher (P < 0.05) cytotoxicity and antioxidant activity in LNCaP. The finding of this study provides a scientific basis for using kadzu and moringa in future development of chemotherapeutic drugs against hormone-sensitive prostate cancer.

• Nutrition Research and Practice
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• v.17 no.2
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• pp.241-256
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• 2023

BACKGROUND/OBJECTIVES: Diabetes-specific oral nutritional supplements (ONS) have anti-hyperglycemic effects, while D-allulose exerts anti-diabetic and anti-obesity effects. In this study, we investigated the efficacy and safety of diabetes-specific ONS, including allulose, on glycemic and weight changes in overweight or obese patients with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A single-arm, historical-control pilot clinical trial was conducted on 26 overweight or obese patients with T2DM (age range: 30-70 yrs). The participants were administered 2 packs of diabetes-specific ONS, including allulose (200 kcal/200 mL), every morning for 8 weeks. The glycemic profiles, obesity-related parameters, and lipid profiles were assessed to evaluate the efficacy of ONS. RESULTS: After 8 weeks, fasting blood glucose (FBG) level significantly decreased from 139.00 ± 29.66 mg/dL to 126.08 ± 32.00 mg/dL (P = 0.007) and glycosylated hemoglobin (HbA1c) improved (7.23 ± 0.82% vs. 7.03 ± 0.69%, P = 0.041). Moreover, the fasting insulin (δ: -1.81 ± 3.61 μU/mL, P = 0.017) and homeostasis model assessment for insulin resistance (HOMA-IR) (δ: -0.87 ± 1.57, P = 0.009) levels decreased at 8 weeks, and body weight significantly decreased from 67.20 ± 8.29 kg to 66.43 ± 8.12 kg (P = 0.008). Body mass index (BMI) also decreased in accordance with this (from 25.59 ± 1.82 kg/m² to 25.30 ± 1.86 kg/m², P = 0.009), as did waist circumference (δ: -1.31 ± 2.04 cm, P = 0.003). CONCLUSIONS: The consumption of diabetes-specific ONS with allulose in overweight or obese patients with T2DM improved glycemic profiles, such as FBG, HbA1c, and HOMA-IR, and reduced body weight and BMI.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.42 no.3
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• pp.263-269
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• 1997

To cope with increasing importance of water stress in food crop production, some physiological characteristics, their cultivar-differences and grain yield of winter barley cultivars in response to water stress during reproductive stages were studied employing three covered-barley cultivars, Milyang 12, Durubori, and Olbori, one naked-barley cultivar, Baegdong, and one two-row malting-barley cultivar, Hyangmaeg. The barley grown in pot-soil was conditioned for 10 days under water stress, varying the time of water stress : 20 days before heading, 10 days before heading and the time of heading. The decrease in growth due to water stress varied greatly with the cultivars and time of water stress. The greatest injury occurred when water stress was imposed for 10 days from 10 days before heading : the culm length of water-stressed plants have shown reduced by 85∼98％ of the non-stressed; the number of spikes per plant by 52∼83%; the number of grains per spike by 71∼86%; 1,000-grain weight by 80∼84%; yield per pot by 60∼94%. The number of spikes per plant as one of yield components was most sensitively affected. As a whole, the drought resistance of cultivars was high in the order of Olbori> Milyang 12 and Durubori> Hyangmaeg>Baegdong. On rewatering the plants after termination of the water stress treatment the recovery rate of free proline content and relative turgidity of flag leaf were higher in 3 covered-barley cultivars, and lower in cultivars Baegdong and Hyangmaeg.

• Earthquakes and Structures
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• v.24 no.6
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• pp.455-475
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• 2023

The present study investigates the non-linear soil-pile interaction using three-dimensional (3D) non-linear finite element models. The numerical models were validated by using the results of extensive pile load and shaking table tests. The pile performance in liquefiable and non-liquefiable soil has been studied by analyzing the liquefaction ratio, pile lateral displacement (LD), pile bending moment (BM), and frictional resistance (FR) results. The pile models have been developed for the different ground conditions. The study reveals that the results obtained during the pile load test and shaking cycles have good agreement with the predicted pile and soil response. The soil density, peak ground acceleration (PGA), slenderness ratio (L/D), and soil condition (i.e., dry and saturated) are considered during modeling. Four ground motions are used for the non-linear time history analyses. Consequently, design charts are proposed depended on the analysis results to be used for design practice. Eleven models have been used to validate the capability of these charts to capture the soil-pile response under different seismic intensities. The results of the present study demonstrate that L/D ratio slightly affects the lateral displacement when compared with other parameters. Also, it has been observed that the increasing in PGA and decreasing L/D decreases the excess pore water pressure ratio; i.e., increasing PGA from 0.1 g to 0.82 g of loose sand model, decrease the liquefaction ratio by about 50%, and increasing L/D from 15 to 75 of the similar models (under Kobe earthquake), increase this ratio by about 30%. This study reveals that the lateral displacement increases nonlinearly under both dry and saturated conditions as the PGA increases. Similarly, it is observed that the BM increases under both dry and saturated states as the L/D ratio increases. Regarding the acceleration histories, the pile BM was reduced by reducing the acceleration intensity. Hence, the pile BM decreased to about 31% when the applied ground motion switched from Kobe (PGA=0.82 g) to Ali Algharbi (PGA=0.10 g). This study reveals that the soil conditions affect the relationship pattern between the FR and the PGA. Also, this research could be helpful in understanding the threat of earthquakes in different ground characteristics.