• Maxillofacial Plastic and Reconstructive Surgery
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• 제27권6호
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• pp.501-509
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• 2005

Ameloblastoma is a common odontogenic benign tumor of the jaw bone. However, it might be albe to infiltrate into the adjacent tissue, causing bony destruction and high recurrent rate. The aim of the study is to understand the biologic behavior of recurred ameloblastoma through immunohistochemical study. The PCNA, Ki-67, p53 and cytokeratin 17, cytokeratin 18 antibody staining were used. There was significant difference of positive reaction between non-recurred ameloblastoma and recurred ameloblastoma in PCNA and cytokeratin 17. There were no significant difference of positive reaction between non-recurred ameloblastoma and recurred ameloblastoma in p53, Ki-67 and cytokeratin 18. From the above results, it is suggested that the recurrence of ameloblastoma is related to positive reactions of PCNA and cytokeratin 17 and the progonsis of the recurrence of ameloblastoma is able to be predicted by using PCNA and cytokeratin 17.

• Journal of Oral Medicine and Pain
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• 제33권2호
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• pp.219-228
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• 2008

본 연구는 측두하악장애 재발환자의 증상과 보존적 치료결과에 대하여 알아보고자 1991년부터 2001년까지 부산대학병원 구강내과에 내원하여 측두하악장애로 진단되어 약물요법, 물리치료, 교합안정장치 등 보존적 치료를 통해 증상이 호전되어 치료 종결하였으나 1992년부터 2002년 사이에 증상이 재발하여 재치료하여 치료 종결된 환자 53명에서 치료 전, 후의 진단명, 증상, 치료방법, 치료횟수, 치료결과를 비교, 연구하여 다음과 같은 결과를 얻었다. 1. 재발군과 원발군은 모두 보존적 치료로 증상이 현저히 개선되었다. 2. 재발군과 원발군의 초진시 증상은 통증, 최대 편이개구량은 차이가 없었으나 관절잡음과 개구제한은 원발군에서 높은 경향을 보였다. 3. 재발군과 원발군의 치료 종결시 증상은 통증, 개구제한, 관절잡음, 최대 편이개구량에서 별 차이를 보이지 않았다. 4. 재발군과 원발군 모두 치료방법, 성, 병명에 따른 치료결과의 차이는 없었다. 5. 치료 횟수에 따른 치료 결과에서 횟수가 재발군에서 10회 미만으로 줄어드는 경향을 보였다.

• 대한한방내과학회지
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• 제28권2호
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• pp.385-390
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• 2007

Objective : The aim of the present study is to derive further studies evaluating the effectiveness of oriental medical treatment on recurred squamous cell carcinoma of the lung. We present a case of recurred squamous cell lung carcinoma patient who has survived more than 7 years. Method : We followed all treatments and examinations. We prescribed the patient take Hang-Am-Dan (HAD) three times a day for 6 years. Computed tomography (CT) was performed to evaluate the therapeutic efficacy. Results : The patient has survived for over 7 years. CT showed stable state (SD). Conclusion : This case may give us a possibility of that oriental medical treatment offers potential benefits for patients with recurred squamous cell lung carcinoma.

• 대한족부족관절학회지
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• 제20권1호
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• pp.32-35
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• 2016

We reported on a rare case of recurred macrodystrophia lipomatosa of the foot, and reviewed the literature. A 62-year-old male patient presented with right foot second toe pain; preoperative magnetic resonance imaging and radiograph examination was performed. After surgery the biopsy confirmed the diagnosis. American Orthopaedic Foot and Ankle Society score was checked before and after surgery. Wide excision of the affected area including ray amputation is an effective way to prevent recurrence and relieve the pain after surgery. The 2nd toe ray amputation was performed in the treatment of recurred macrodystrophia lipomatosa of the foot, and is thought to be an effective way to relieve pain and prevent recurrence. After minimally invasive surgery with complete excision surgery, additional data on recurrence and pain relief rate are needed.

• Journal of Oral Medicine and Pain
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• 제32권2호
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• pp.241-250
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• 2007

측두하악장애 재발 환자의 증상과 보존적 치료결과에 대하여 알아보고자 1994년부터 2002년까지 부산대학병원 구강내과에 내원하여 측두하악장애로 진단되어 약물요법, 물리치료, 교합안정장치 등 보존적 치료를 받은 환자 104명(원발군, 대조군)과 1991년부터 2001년까지 부산대학병원 구강내과에 내원하여 측두하악장애로 진단되어 보존적 치료를 받은 후에 증상이 재발하여 1992년부터 2002년에 걸쳐 보존적인 방법으로 재치료를 받은 환자 54명(재발군, 실험군)을 대상으로 서로 비교하여 다음과 같은 결과를 얻었다. 1. 원발군과 재발군은 모두 보존적 처치로 증상이 현저히 개선되었다. 2. 원발군과 재발군의 초진시 증상은 통증, 개구제한, 최대 편이개구량은 차이가 없었으나 관절잡음은 원발군에서 높았다. 3. 원발군과 재발군의 치료 종결시 증상은 통증, 개구제한, 최대 편이개구량은 차이가 없었으나 관절잡음은 재발군에서 높았다. 4. 원발군과 재발군 모두 치료방법, 성, 병명에 따른 치료결과의 차이는 없었다. 5. 원발군은 치료기간이 6개월 이상 일수록, 치료횟수가 10회 이상일수록 치료결과가 양호하였다.

• 동의생리병리학회지
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• 제27권1호
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• pp.148-151
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• 2013

This study is aimed to investigate the effects of intravenous Cultivated Wild Ginseng Pharmacopuncture(CWGP) and the FOLFIRI chemotherapy combination on recurred and metastatic ascending colon cancer patient. A 42-years-old man was diagnosed as ascending colon adenocarcinoma on 9th Mar. 2011. After performing right hemicolectomy and 12 cycles of FOLFOX chemotherapy recurrence at hemicolectomy site and metastases in liver, spleen and lungs were found on 7th Feb. 2012. Intravenous CWGP were performed during total 12 cycles of FOLFIRI chemotherapy from 3rd Mar. 2012 to 27th Sep. 2012. The effects and toxicities of CWGP and FOLFIRI chemotherapy combination were evaluated with PET torso(AA) and National Cancer Institute-Common Toxicity Criteria. The tumor mass in the splenic hilum and liver S4 was disappeared and multiple pulmonic lymph nodules were decreased in size. The recurred lesion on the site of right hemicolectomy showed no changes. During the treatment the patient had no toxicity over grade 1.

• Journal of Korean Neurosurgical Society
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• 제38권2호
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• pp.116-120
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• 2005

Objective : The aim of this study is to analyze the clinical symptoms, radiological changes, interval from first operation to symptom recurrence and to propose the proper treatment method for re-operated patients following chronic subdural hematoma surgery. Methods : Between January 1992 and April 2003, 18 of 138patients of chronic subdural hematoma repeatedly underwent surgical treatment. The symptoms, mental status by Bender grade, radiological hematoma size and midline shifting, interval from symptom onset to diagnosis, surgical method and prognosis by Glasgow outcome scale[GOS] between the first attack and the recurrence were compared. Results : The symptoms at the time of recurrence were nearly the same as with the first attack, but two patients[2/18, 11.1%] showed a more declined mentality. In addition, the recurred hematoma sizes were the same or large than those previously found. Many patients were recurred within two weeks[13/18, 72.2%]. Most patients were operated on using the previous burr hole, with the exception of one patient who recurred at a different site. All patients had a good prognosis more than GOS 4 [GOS 4:4, GOS 5:12], but two died due to extracranial complication and infection. Conclusion : These results suggest that the early diagnosis and treatment are important, mostly recurred same symptoms within two weeks. Re-operation using the previous burr hole site is a good method.

• Archives of Plastic Surgery
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• 제33권4호
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• pp.491-494
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• 2006

Purpose: To report the case of recurred malignant proliferating trichilemmal tumor on scalp Methods: Case report and literature review Results: A 40-year-old man presented with a recurred malignant proliferating trichilemmal tumor, which developed on the occipital area. It was $8{\times}9{\times}4.5cm$ in size, protruded, firm and non-tender mass. This tumor was widely excised including normal skin margin and pericranium. Immediate reconstruction using free latissimus dorsi muscle flap and skin graft were done. Histopathologic examination revealed abrubt, compact trichilemmal keratinization in the central area of lobular epithelial proliferation. Conclusion: There has been no recurrence of tumor during follow-up period of nine months without adjuvant chemotherapy or radiotherapy.

• Journal of Korean Neurosurgical Society
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• 제39권2호
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• pp.96-101
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• 2006

Objective : The authors assess the long term effectiveness of gamma knife radiosurgery[GKS] for remnant or recurred craniopharyngiomas on tumor control and possibly set proper radiation dose for tumor control with utmost preservation of the adjacent structures. Methods : Sixteen GKS were done in 14 patients with recurred or remnant craniopharyngiomas after surgery. Mean follow up duration was 44.2 months [range $11.3{\sim}123.6\;months$]. Follow up MR imagings were analyzed. Results : Mean tumor volume was $3.6cm^3$ [range $0.6{\sim}18cm^3$] and mean margin dose was 12.2Gy [range $8{\sim}22.4Gy$]. Tumor control was achieved in 87.5% [14 of 16 tumors] which were either solid or cystic in nature. Dose to optic apparatus was mean 7.9Gy and no radiation related complications were observed. Conclusion : GKS seems to be effective treatment modality for craniopharyngiomas regardless of nature of tumor whether it is cystic or solid. Dose of 8 to 8.5Gy may be sufficient to achieve long term tumor control for remnant or recurred craniopharyngiomas.

• 대한두경부종양학회지
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• 제31권2호
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• pp.11-15
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• 2015

Background and Objectives: This study aimed to analyze the features of patients with papillary thyroid carcinoma (PTC) recurred as distant metastases (DM). Materials and Method: We retrospectively reviewed and analyzed clinical records of 63 patients who were treated for PTC recurred as DM between 2000 and 2006. Univariate and multivariate analyses of various clinical factors were performed. Results: Male patients were 12, and female patients were 51. The 5- and 10-year survival rates for PTC recurred as DM were 85% and 73%, respectively. Size of tumor, multiplicity of tumor, lateral neck node metastasis, and RAI ablation therapy with other treatments such as surgery were associated with survival rate (p < 0.005) in univariate analysis. The lateral neck node metastasis[p =0.039, hazard ratio=2.2(95% CI. 1.18~3.24)] and multiple organ DM[p =0.041, hazard ratio=2.18(95% CI. 1.03~2.89)] were related to the survival in multivariate analysis. Conclusion: PTC recurred as DM is uncommon (2.2%). The size of tumor, the multiplicity of tumor, lateral neck node metastasis and RAI ablation therapy with other treatments for DM were revealed as associated factors for the survival. Evaluation of DM should be considered in patients with PTC during long-term follow-up.