• Korean Journal of Acupuncture
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• v.35 no.4
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• pp.187-202
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• 2018

Objectives : Non-invasive transcranial electrical stimulation is one of therapeutic interventions to change in neural excitability of the cortex. Transcranial electro-acupuncture (TEA) can modulate brain functions through changes in cortical excitability as a model of non-invasive transcranial electrical stimulation. Some composites of fermented Scutellaria baicalenis (FSB) can activate intercellular signaling pathways for activation of brain-derived neurotrophic factor that is critical for formation of neural plasticity in stroke patients. This study was aimed at evaluation of combinatory treatment of TEA and FSB on behavior recovery and cortical neural excitability in rodent focal stroke model. Methods : Focal ischemic stroke was induced by photothrombotic injury to the motor cortex of adult rats. Application of TEA with 20 Hz and $200{\mu}A$ in combination with daily oral treatment of FBS was given to stroke animals for 3 weeks. Motor recovery was evaluated by rotating bean test and ladder working test. Electrical activity of cortical pyramidal neurons of stroke model was evaluated by using multi-channel extracellular recording technique and thallium autometallography. Results : Compared with control stroke group who did not receive any treatment, Combination of TEA and FSB treatment resulted in more rapid recovery of forelimb movement following focal stroke. This combination treatment also elicited increase in spontaneous firing rate of putative pyramidal neurons. Furthermore expression of metabolic marker for neural excitability was upregulated in peri-infract area under thallium autometallography. Conclusions : These results suggest that combination treatment of TEA and FSB can be a possible remedy for motor recovery in focal stroke.

• Journal of the Korean Society of Mineral and Energy Resources Engineers
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• v.55 no.6
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• pp.660-669
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• 2018

Enhanced oil recovery (EOR) is a method used to improve the recovery factor of remaining hydrocarbon in reservoir. Polymer and surfactant EOR techniques have limitations depending on reservoir or production conditions (temperature, salinity, etc.) because the polymer and surfactant are highly affected by the reservoir conditions. In this study, analysis of the current improvements to chemical substances and application technologies was performed based on recent research data. Conventional polymer is readily degraded by the conditions of high temperature and high salinity. Therefore, new polymers and injection techniques have been developed to remediate such problems. In addition, surfactant applicable to shale and carbonate reservoirs is developed as petroleum recovery expands to unconventional reservoirs. However, these chemical substances are not widely used in the current oil fields due to high costs. Therefore, further studies must be conducted to reduce the cost and thus increase the effectiveness of EOR techniques.

• Korean Journal of Metals and Materials
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• v.48 no.3
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• pp.203-209
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• 2010

An application of the instrumented indentation technique has been expanded from the measurements of hardness and elastic modulus to the analysis of residual stress. A slope of the indentation loading curve increases (or decreases) according to compressive (or tensile) residual stress. A theoretical equation has been established for quantifying residual stress from the slope change. However, a precise observation of the remnant indents is indispensible because the theoretical approach needs actual contact information. In addition, the conventional hardness test is still used for predicting the residual stress distribution of welded joints. Thus, we observed the three-dimensional morphologies of the remnant indents formed on artificial stress states and analyzed stress effects on morphological recovery of the indents. First, a depth recovery ratio, which has been regarded as a sensitive stress indicator, did not show a clear dependency with the residual stress. Thus an analysis on volumetric recovery was tried in this study and yielded a inverse proportional behavior with the residual stress. In addition, an elastic to plastic volume recovery ratio showed more significant correlation with the residual stress.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2523-2526
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• 2012

Introduction: Febrile neutropenia is a relatively frequent event in cancer patients treated with chemotherapy and improvement in absolute neutrophil count (ANC) has been linked directly to improved outcome. Evaluation of granulocyte colony stimulating factors (GCSFs) for treatment has shown reduced incidences of episodes of prolonged neutropenia and protracted hospitalization. To determine absolute neutrophil counts with GCSF in febrile neutropenic cancer patients admitted to a tertiary care centre and to co-relate the improvement in ANC with mortality and hospital discharge. Methods: A prospective cross sectional study was carried at an oncology ward at Aga Khan University hospital from January 2010 to June 2011. All adult patients who were admitted and treated with GCSF for chemotherapy induced febrile neutropenia were included. Multivariable regression was conducted to identify the factors related with poor outcomes. Results: A total of 131 patients with febrile neutropenia were identified with mean age of 43.2 (18-85) years, 79 (60%) being ${\leq}50$. Seventy-five (57%) had solid tumors and 56 (43%) hematological malignancies, including lymphoma. Fifty seven (43.5%) had an ANC less 100 cells/$mm^3$, 34 (26%) one between 100-300 cells/$mm^3$ and 40 (31%) an ANC greater than 300 cells/$mm^3$. Thirty (23%) patients showed ANC recovery in 1-3 days, and 74(56%) within 4-7 days. Thirteen (10%) patients showed no recovery. The overall mortality was 18 (13.7%) patients. The mean time for ANC recovery seen in hematological malignancies was 6.34 days whereas for solid tumors it was 4.88 days. Patients with ANC <100 cells/$mm^3$ were more likely to die than patients with ANC >300 cells/$mm^3$ by a factor of 4.3. Similarly patients >50 years of age were 2.7 times more likely to die than younger patients. Conclusion: Our study demonstrated that use of GCSF, in addition to intravenous antibiotics, in treatment of patients with chemotherapy induced febrile neutropenia accelerates neutrophil recovery, and shortens antibiotic therapy and hospitalization. We propose to risk classify the patients at the time of admission to evaluate the cost effectiveness of this approach in a resource constrained setup.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.386-394
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• 2016

This study investigates the validity of a Korean version of the Client Assessment Summary (CAS), which is a tool used to assess the recovery of alcoholics. We investigated the Korean CAS's suitability for use in assessing the scale of recovery scale of general alcoholics in Korea. In this study, we analyzed the data of 205 abstaining alcoholics in order to determine the validity of the Korean CAS. We undertook relationship analyses of CAS contents, reliability, and composition validity through factor analysis. In addition, we assessed ARS, abstinence period, abstinence self-efficacy, illness insight, and motivation change variables. The factor analysis results, performed after verification of content suitability by assessing 12 questions and 4 factors, confirmed the tool's composition validity, with the results showing relatively high values (R2 = 76.26%, communality ${\geq}0.6$, and KMO = 0.92). Moreover, internal consistency was acceptable (Cronbach's alpha = 0.92), and the correlations among ARS, abstinence self-efficacy, illness insight, and motivation change variables confirmed the validity of the Korean CAS. The proposed Korean CAS is expected to be useful when academically and clinically assessing the recovery of alcoholics; thereby, eventually contributing to successful recoveries from alcoholism.

• Journal of the Korean Society of Groundwater Environment
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• v.7 no.2
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• pp.89-96
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• 2000

Slug tests are the most widely used field method for quantification of hydraulic conductivity of porous media. Well recovery is affected by well casing, borehole radii, screened length, hydraulic conductivity, and specific storage of porous media. In this study, a new slug tests model was developed through finite element approximation and the validity and usefulness of the model were tested in various ways. Water level fluctuation in a well under slug test and cons-equent groundwater flow in the surrounding porous medium were appropriately coupled through estimation of well-flux using an iteration technique. Numerical accuracy of the model was verified using the Cooper et al. (1967) solution. The model has advantages in simulations for monitored slug tests, partial penetration, and inclusion of storage factor. Volume coverage of slug tests is significantly affected by storage factor. Magnitude and speed of propagation of head changes from a well increases as storage factor becomes low. It will be beneficial to use type curves of monitored head transients in the surrounding porous formation for estimation of specific storage. As the vertical component of groundwater flow is enhanced, the influence of storage factor on well recovery decreases. For a radial-vertical flow around a partially penetrated well, deviations between hydraulic estimates by various methods and data selection of recovery curve are negligible on practical purposes, whereas the deviations are somewhat significant for a radial flow.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.6
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• pp.17-29
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• 2021

Recently, as social distancing have been raised due to the re-spread of COVID-19, the number of serial entrepreneurs who are closing their business is rapidly increasing. Learning from failure is a source of success, but business failure can result in psychological and economic losses and negative emotions of the serial entrepreneur. At this point, it is very important to find a way to recover the negative emotions caused by business failures of serial entrepreneurs. Recently, a strategic model has emerged to deal with the negative emotions of grief caused by business failures of serial entrepreneurs. This study identified the recovery factors from the grief of business failures of serial entrepreneurs and analyzed Shepherd's(2003) three areas: loss orientation, restoration orientation, and dual process. To this end, individual in-depth interviews were conducted with 12 small business serial entrepreneurs who challenged re-startup to identify the attributes of recovery factors that were not identified with quantitative data. As a result of the study, first, recovery factors were investigated in three areas: individual orientation, family orientation, and network orientation. It was found to help improve recovery in nine categories: self-esteem, persistence, personal competence, hobbies, self-confidence, family support, networks, religion, and social support. Second, recovery obstacle factors were investigated in three areas: psychological, economic, and environmental factors. Nine categories including family, health, social network, business partner, competitor, partner, fund, external environment, and government policy were found to persist negative emotions. Third, the emotional processing process for grief was investigated in three areas: loss orientation, restoration orientation, and dual process. Ten categories such as family, partner support, social member support, government support, hobbies, networks, change of business field, moving, third-party perspective, and meditation were confirmed to enhance rapid recovery in the emotional processing process for grief. The implications of this study are as follows. The process of recovering from the grief caused by business failures of serial entrepreneurs was attempted by a qualitative study. By extending the theory of Shepherd(2003), This study can be applied to help with recovery research. In addition, conceptual models and propositions for future empirical research were presented, which can be discussed in carious academic ways.

• The Transactions of the Korean Institute of Power Electronics
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• v.19 no.1
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• pp.23-30
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• 2014

This paper proposes a single power-conversion ac-dc converter with a dc-link capacitor-less and high power factor. The proposed converter is derived by integrating a full-bridge diode rectifier and a series-resonant active-clamp dc-dc converter. To obtain a high power factor without a power factor correction circuit, this paper proposes a suitable control algorithm for the proposed converter. The proposed converter provides single power-conversion by using the proposed control algorithm for both power factor correction and output control. Also, the active-clamp circuit clamps the surge voltage of switches and recycles the energy stored in the leakage inductance of the transformer. Moreover, it provides zero-voltage turn-on switching of the switches. Also, a series-resonant circuit of the output-voltage doubler removes the reverse-recovery problem of the output diodes. The proposed converter provides maximum power factor of 0.995 and maximum efficiency of 95.1% at the full-load. The operation principle of the converter is analyzed and verified. Experimental results for a 400W ac-dc converter at a constant switching frequency of 50kHz are obtained to show the performance of the proposed converter.

• Journal of Microbiology and Biotechnology
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• v.11 no.4
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• pp.644-648
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• 2001

The biological control potential of entomopathogenic nematodes (EPN) can be enhanced by improved culture efficiency. Optimization of the media is a key factor for improving in vitro mass production of entomopathogenic nematodes. This study reports the effect of medium concentration. The medium is a combination of carbohydrates, lipids, proteins, sats, and growth factors, on the growth of Heterorhabditis bacteriophora and its symbiotic bacterium Photorhabdus liminescens. The overall optimal medium concentration for nematode recovery, hermaphrodite size, bacterial mass, infective juveniles (IJs) yield, and doubling time was 84 g/l. At this concentration rate, the doubling time of IJs production and the biomass of symbiotic bacteria was 1.6 days and 12.8 g/l, respectively. The maximum yield of $2.4{\times}{10^5}IJs/ml$ was attained within a one-generation cycle (eight days). The yield coefficient was $2.8{\times}{10^6}$ IJs/g medium, and the maximum productivity was $3.1{\times}{10^7}$ IJs per day. Medium concentration affected two independent factors, recovery and hermaphrodite size, which in turn influenced the final yield.

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.5
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• pp.653-658
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• 2013

For towing the new type armored vehicle and maintaining the close support, the armored recovery vehicle(ARV) with winch and crane has been developed. In case of crane, it is mainly used to salvage heavy objects by rotational and vertical motion. Especially, the crane bracket is very important parts due to fixing the ARV's body and rotary joint and preventing the force rotation of crane. Therefore, the crane bracket needs to have an enough strength to endure the high load and it is very important to analyze the stress distribution under loads. In the present work, the experimental and analytical investigation on structural integrity evaluation of crane bracket were carried out. The simulation of three-dimensional finite element method(FEM) was compared with experimental datum. From the numerical results, the FEM simulations corresponded well with th experimental results and the structural safety was confirmed by safety factor.