• Title/Summary/Keyword: Recovery effort

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Improvement of Analytical Method for Residue Pesticides in Herbal Medicines Using Macroporous Diatomaceous Earth Column (다공성 규조토 컬럼을 이용한 한약재 중 잔류농약 분석법 개선)

  • Hwang, Jeong-In;Jeon, Young-Hwan;Kim, Hyo-Young;Kim, Ji-Hwan;Ahn, Ji-Woon;Seok, Da-Rong;Lee, Yoon-Jeong;Park, Ju-Young;Kim, Do-Hoon;Kim, Jang-Eok
    • The Korean Journal of Pesticide Science
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    • v.15 no.2
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    • pp.140-148
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    • 2011
  • The official analytical method of residue pesticides in herbal medicines by KFDA cannot be applied to all of the pesticides and herbal medicines because of various active materials in herbal medicines and various physicochemical properties of pesticides. Moreover, liquid-liquid partition uses harmful solvents such as methylene chloride and is consuming a lot of time and effort. In order to improve the problems, we have studied for the availability of the analytical method applying the macroporous diatomaceous earth (MDE) column instead of liquid-liquid partition to simultaneously analyze five pesticides in two dried herbal medicines. The results showed that the recovery rates of acetamiprid and azoxystrobin in Astragalus root by GC/ECD ranged from 89.6 to 94.1%, from 86.8 to 94.4%, respectively, and those of bifenthrin, chlorfenapyr, chlorpyrifos in Cnidii Rhizoma by GC/MS ranged from 83.6 to 88.4%, from 77.4 to 83.8%, from 82.6 to 84.3%, respectively. Also, the coefficients of variation (CV) for triplication ranged from 0.5 to 1.7%. The results satisfied the criteria of residue pesticide analysis, setting 70~120% for the recovery rate and below 10% for the coefficient of variation. The improved methods are safer to residue pesticide analysts, faster and less laborious than the KFDA official method.

A Research on Addictive Use of Smartphone by University Students (대학생의 스마트폰 중독적 사용 경험 연구)

  • Ko, Ki-Sook;Lee, Myoun-Jae;Kim, Young-Eun
    • Journal of Digital Contents Society
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    • v.13 no.4
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    • pp.501-516
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    • 2012
  • The purpose of this study is to explore the fundamental nature and meanings of the experiences of university students with regard to their smartphone usage in order to prevent smartphone addiction and provide guidelines to develop effective interventions. Nine university students who were currently enrolled in an university located in a Korean province participated in this study. In-depth interviews were conducted from June of 2012 to July of 2012, and data were analyzed using Colaizzi's phenomenological qualitative method. As a results, five theme and 40 subthemes of experiences of problematic smartphone usage were identified. Those themes include 1) a desperate try to connect with others(exposing oneself without appropriate self-protection, seeking emotional comfort, hurt and mistrust); 2) excessive use of smartphone and loss of self-control(more smartphone usage over computer/over-immersion/excessive usage/habituation, loss of self-control); 3) psychological difficulties(excessive attachment and dependence, separation anxiety, clingingness, reduced patience) ; 4) threats to daily functioning (changes in priorities, regressed independent daily functioning, irregular daily patterns, health problems, interruptions from free messenger, academic difficulties); 5) potential for recovery(conflictual feelings and doubts over smartphone usage, importance of interpersonal(face-to-face) communications, willingness to cut down the use, hope for recovery). This study provided suggestions for the prevention effort against smartphone addiction.

A Study of Perceived Discomfort of The Patients Under Local Anesthesia - Centering Around the Development of Measures - (국소마취 수술환자의 불편감에 관한 연구 - 도구개발을 중심으로 -)

  • Lee, Gyeong Sug;Kim, Mi Ja;Park, Sun Mi;Paek, Sun Young;Lee, Yang Sug;Bae, Sang Do;Choi, Jung Hoon
    • Quality Improvement in Health Care
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    • v.7 no.1
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    • pp.6-17
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    • 2000
  • Background : This study was attempted to provide a basic information necessary for the development of measures evaluating perceived discomfort of the patients under local anesthesia and the developments of nursing intervention and nursing standard. Method : The study subjects were a convenience sample of 100 surgical patients under local anesthesia. The researcher visited the patients directly and explained the purpose of the study to them. Then they were asked to fill out questionnaires which were developed and structured by the researcher, under their prior permission. Out patient's data were collected at recovery room after operation. Results : Factor analysis on measures evaluating the patients under local anesthesia showed that the measures consisted of eight factors including "explanation", "humane treatment", "motion limitation", "pain", "no togetherness", "waiting", "the environment of operating room", and "unkindness". When analyzing each of the factors regarding their degree of contribution to perceived discomfort, it was found that "waiting" was highest in terms of the degree. According to general chara-cteristics of the sampled patients, the factor of "explanation" contributed to perceived discomfort more in male patients than female ones. Regarding parts of medical examination, the patients of otorhinolaryngology felt perceived discomfort most because of the factor of "pain". Conclusion : To relieve perceived discomfort the patients under local anesthesia require providing individually systematized nursing services which can reduce perceived discomfort according to each of the factors. In doing so, an unlimited attention and much effort should be given to realize CQI reaching the dimension of increase in comfort as well as decrease perceived discomfort.

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Optimization of Bio-Methane Gas Enrichment Process for City Gas Supply (도시가스용 바이오가스 메탄농축공정 최적화)

  • Ko, Sang-Wook;Lee, Kyung Jin;Moon, Myong Hwan;Baek, Ju Hong;Ko, Jae Wook
    • Journal of the Korean Institute of Gas
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    • v.21 no.4
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    • pp.76-83
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    • 2017
  • Biogas, combine with ever-increasing natural gas demand, has been on the center stage in South Korea for the early part of twenty first century in an effort to reduce the emission of global warming gases. With the passage of legal system of City Gas Business Law in 2014, the biogas has its place of production and distribution to consumers. However, it has a room for its technological improvements in terms of enrichment, by separating carbon dioxide and removing impurities efficiently. For these improvements, four different methane enrichment processes were tested in this study; membrane separation, water absorption, Chemical Absorption and Adsorption. A variety of operation scenarios were applied to the processes and the best practices were drawn out. The optimum process was selected based on case study results. Methane produced in this study showed 97% purity and 98% recovery rate, which meets the requirements of the City Gas quality standards.

Determination of Oxycarboxin Residues in Agricultural Commodities Using HPLC-UVD/MS (HPLC-UVD/MS를 이용한 농산물 중 Oxycarboxin의 분석)

  • Choung, Myoung-Gun
    • Korean Journal of Environmental Agriculture
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    • v.37 no.2
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    • pp.117-124
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    • 2018
  • BACKGROUND: Oxycarboxin(5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide-4,4-dioxide) as oxanthiin is a systemic fungicide commonly used for control of various pathogens in agronomic and horticultural crops. In an effort to develop an analytical method to trace the fungicide, a method using HPLC equipped with UVD/MS was studied. METHODS AND RESULTS: Oxycarboxin was extracted with acetone from hulled rice, soybean, Kimchi cabbage, green pepper, and apple samples. The extract was diluted with saline water, followed by liquid-liquid extraction with methylene chloride. Florisil column chromatography was employed for the purification of the extracts. Oxycarboxin was determined on a Zorbax SB-AQ $C_{18}$ column by HPLC with UVD. Accuracy of the proposed method was validated by the recovery tests from crop samples fortified with oxycarboxin at 3 levels per crop. CONCLUSION: Mean recoveries ranged from 78.3% to 96.1% in five representative agricultural commodities. The coefficients of variation were less than 10%, and limit of quantitation of oxycarboxin was 0.04 mg/kg. A confirmatory technique using LC/MS with selected-ion monitoring was also provided to clearly identify the suspected residue. The method was reproducible and sensitive to determine the residue of oxycarboxin in agricultural commodities.

Surgically Treated Anterior Communicating Artery Aneurysm

  • Koo, Sang-Keun;Song, Yeung-Jin;Huh, Jae-Taeck
    • Journal of Korean Neurosurgical Society
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    • v.37 no.6
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    • pp.405-409
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    • 2005
  • Objective: The purpose of this study is to assess the factors related to the outcome of 84 patients who underwent surgery for anterior communicating Artery(ACoA) aneurysms. Methods: The authors review 84 patients who were undertaken from January 1998 to May 2004. In the management of ACoA aneurysms, the outcome was based on several factors: Clinical condition, Distribution of hemorrhage, Time between aneurysmal rupture and surgery, Direction and shape of the aneurysm. Results: The incidence rate of the ACoA aneurysm was 35%. Seventy four patients were classified as those having a good recovery, but 5 patients suffered from some morbidity and 5 patients died. The rate of good outcome for the patients with Hunt and Hess grade was as follows 100% in grade I, 95% in grade II, 80% in grade III, IV and V. The rate of good outcome for the patients with Fisher grade was as follows 98% in grade I, II and 81% in grade III, IV. Nineteen of 22 patients who underwent early surgery were rated as good, while twenty six of 30 patients for whom surgery was delayed showed a favorable result. The unfavorable outcomes were also attributed by vasospasm or other medical problems. Conclusion: For further improvement of the overall surgical outcome: First, early surgical intervention is recommended for good grade patients. Second, active management of poor grade patients should be scrutinized with early surgery. Third, it is also important to step up the effort to minimize the risk of medical complications to enhance surgical results on top of the mainstay of prevention efforts for vasospasm and rebleeding.

The Countermeasure to the Stages of Crisis Management in the Bioterrorism (생물테러리즘의 위기관리방안)

  • Lee, Kwang-Lyeol
    • Proceedings of the Korea Contents Association Conference
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    • 2009.05a
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    • pp.608-613
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    • 2009
  • This study aims to examine terrorism by biological agents. These days terrorism evolved so rapidly that more than one terror occurs a day in global society as we are on the edge of so-called New-terrorism. One of new examples of new terrorism is Bioterrorism by biological agents. In order to address Bioterrorism we should conduct a study to examine things to be prepared at ordinary times and future plans. As an effort to develop countermeasures against Bioterrorism, anti-terrorism laws should be made on Prevention phases anti-terrorism funding laws as well. Other Bioterrorism laws need to be made. On Response phases initial reaction task force should be ready for making positive initial reaction. A special hospital for CBR(Chemical, Biological, and Radiological) warfare needs to be designated to practice medicine. Biological-Safety-Levels should be constructed by IV levels. Effective public promotion network should be built. On Recovery phases evaluation system needs to be suggested and international cooperative network should be established.

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Strategies for Conservation and Restoration of Freshwater Fish Species in Korea (한국 담수어류의 보존 및 복원 전략)

  • Kang, Eon-Jong;Bang, In-Chul;Yang, Hyun
    • Korean Journal of Ichthyology
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    • v.21 no.sup1
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    • pp.29-37
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    • 2009
  • The tiny fragment of freshwater body is providing home for huge biodiversity and resources for the existence of human. The competing demand for freshwater have been increased rapidly and it caused the declination of biodiversity in recent decades. Unlike the natural process of extinction in gradual progress, the current species extinction is accelerated by human activity. As a result many fish species are already extinct or alive only in captivity in the world and about fifty eight animal species are in endangered in Korea including eighteen freshwater species. Conservation of biodiversity is the process by which the prevention of loss or damage is attained, and is often associated with management of the natural environment. The practical action is classified into in-situ, or ex-situ depending on the location of the conservation effort. Recovery means the process by which the status of endangerment is improved to persist in the wild by re-introduction of species from ex-situ conservation population into nature or translocation of some population. However there are a lot of restrictions to complete it and successful results are known very rare in case. In this article the authors explore some strategies for conservation and restoration of freshwater fish species conducted in Korea for few years. The major causes are discussed in relation with the decline of freshwater fish diversity during few decades and some strategies are evaluated to advance the process of conservation. A study on the Korean bullhead, Pseudobagrus brevicorpus, is introduced as a case for ex-situ conservation and restoration in freshwater ecosystem.

Post-extubation Negative Pressure Pulmonary Edema Complicating Partial Rib Resection -A case report- (늑골 절제술 환자에서 기관 내 튜브 발관 후 발생한 음압성 폐부종 -1예 보고-)

  • Kim, Jae-Jun;Jo, Min-Seop;Cho, Kyu-Do;Park, Yeon-Jin;Kim, Yong-Shin;Cho, Deog-Gon
    • Journal of Chest Surgery
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    • v.40 no.4 s.273
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    • pp.313-316
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    • 2007
  • Negative pressure pulmonary edema (NPPE) during anesthetic recovery is a rare, but potentially serious complication for patients who are undergoing different surgical procedures. The proposed mechanism is the generation of high negative pressure during markedly respiratory effort and upper airway obstruction from glottis closure and laryngospasm, and this all leads to pulmonary edema. We report here on a case of a healthy 26-year-old male who immediately developed NPPE and hemoptysis following extubation after partial rib resection due to benign rib tumor; the patient was treated conservatively. We also include a review of the review literatures.

Localized Surface Plasmon Resonance (LSPR) Biosensors on Metal Nanoparticles with the Design of Bioreceptors

  • Kim, Min-Gon;Park, Jin-Ho;Byun, Ju-Young;Shin, Yong-Beom
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.126-126
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    • 2014
  • Label-free biomolecular assay based localized surface plasmon resonance (LSPR) of noble metal nanoparticles enables simple and rapid detection with the use of simple equipment. Nanosized metal nanoparticles exhibit a strong absorption band when the incident light frequency is resonant with the collective oscillation of the electrons, which is known as the LSPR. Here we demonstrate localized surface plasmon resonance (LSPR) substrates such as plasmonic Au nanodisks fabricated by a nanoimprinting process and gold nanorod-immobilized surfaces and their applications to highly sensitive and/or label-free biosensing. To increase detection sensitivity various bioreceptors weree designed. A single chain variable fragment (scFv) was used as a receptor to bind C-reactive protein (CRP). The results of this effort showed that CRP in human serum could be quantitatively detected lower than 1 ng/ml. Aptamers, which were immobilized on gold nanorods, were used to detect mycotoxins. The specific binding of ochratoxin A (OTA) to the aptamer was monitored by the longitudinal wavelength shift of LSPR peak in the UV-Vis spectra resulting from the changes of local refractive index near the GNR surface induced by accumulation of OTA and G-quadruplex structure formation of the aptamer. According to our results, OTA could be quantitatively detected lower than 1 nM level. Additionally, aptamer-functionalized GNR substrate was quite robust and can be regenerated many times by rinsing at 70 OC to remove bound target. During seven times of washing steps, the developed OTA sensing system could be reusable. Moreover, the proposed biosensor exhibited selectivity over other mycotoxins with an excellent recovery for detection in grinded corn samples, suggesting that the proposed LSPR based aptasensor plays an important role in label-free detection of mycotoxins.

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