• The Journal of Korean Academy of Prosthodontics
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• v.53 no.2
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• pp.150-156
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• 2015

As dental implant treatment becomes popular for both partial and complete edentulous patients, old people with complex systemic diseases also tend to prefer implant-assisted-overdenture or implant-supported-fixed prostheses to conventional complete denture. In this case, 77-year-old female who was on medication for hypertension and osteoporosis and paralyzed on right side due to stroke visited for implant-assisted-overdenture on lower jaw. After oral and radiographic examination, root-assisted magnet overdenture on upper jaw and implant-assisted magnet overdenture on lower jaw are planned. Consequently, overdentures using self-adjusting magnetic attachment(SA) system on both jaws resulted in recovering satisfying function and retention, which is enable to insert and remove with only one hand.

• Korean Journal of Social Welfare
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• v.67 no.3
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• pp.125-150
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• 2015

The purpose of this study is to explore all the deaf marriage experiences. To achieve this purpose, the qualitative case research approach was used to analyze the couple. This researcher following same issues from 5 couples case study analysis. This researcher set 5 titles and analyze from the 5 main issues about the deaf couple's experience as time goes by. The titles are 'finally the marriage spouses both deaf', 'to overcome communications difficulties', 'worried about raising children and get some help from other people and try something', 'try to get over the difficulties and hardships', 'recovering family relationship and challenge.' Through this study, understanding the deaf couples desire in having a family and live a normal life after becoming parents is "in a family deaf culture" wherein they aspire to become more mature and experienced deaf persons. But the meaning of maintaining constancy was not just keeping their situation by taking familiar things hence there were no challenges. Keeping the constancy, maintaining a family since marriage, delivering and raising their children, make them realize some laws of life. They correspond well and break the narrow limited cultural way of thinking and recognized a broader sense of understanding while keeping constancy. Their life that is keeping their culture and experiencing matured life will be a good theoretical basis for understanding the deaf culture.

• The Journal of the Korea Contents Association
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• v.10 no.2
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• pp.72-80
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• 2010

The 1Gbps clock and data recovery (CDR) circuit using the proposed multi-point phase detector (PD) is presented. The proposed phase detector generates up/down signals comparing 3-point that is data transition point and clock rising/falling edge. The conventional PD uses the pulse width modulation (PWM) that controls the voltage controlled oscillator (VCO) using the width of a pulse period's multiple. However, the proposed PD uses the pulse number modulation (PNM) that regulates the VCO with the number of half clock cycle pulse. Therefore the proposed PD can controls VCO preciously and reduces the jitter. The CDR circuit is tested using 1Gbps $2^{31}-1$ pseudo random bit sequence (PRBS) input data. The designed CDR circuit shows that is capable of recovering clock and data at rates of 1Gbps. The recovered clock jitter is 7.36ps at 1GHz and the total power consumption is about 12mW. The proposed circuit is implemented using a 0.18um CMOS process under 1.8V supply.

• The Journal of Pediatrics of Korean Medicine
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• v.28 no.4
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• pp.1-29
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• 2014

Objectives Dictamni Radicis Cortex extracts (DRC) has been known to suppress allergic reaction, however the cellular target of DRC and its mode of action remain unclear. The purpose of this study is to investigate the effects of Dictamni Radicis Cortex extracts on DNCB induced atopic dermatitis-like skin lesions of NC/Nga mouse. Methods This study was designed to investigate the effects of DRC extract in the DNP-IgE-induced activation of MC/9 murine mast cell lines in vitro and in the DNCB-induced activation of NC/Nga mouse in vivo. For this investigation, We examined IL-4, IL-5, IL-6, IL-13, TNF-${\alpha}$ and GM-CSF mRNA expression by Real-time PCR, IL-13, MIP-$1{\alpha}$ production by ELISA analysis and manifestations of NFAT1, NFAT2, AP-1 and NF-${\kappa}B$ p65 transcription factors by western blotting in vitro. Then, we examined WBC, eosinophil and neutrophil in NC/Nga mouse, IL-5, IL-13 in serum, IFN-${\gamma}$, IL-4 in the spleenocyte culture supernatant, the absolute cell numbers of $CD4^+$, $CD8^+$, $^+Gr-1^+CD11b$, $B220^+CD23^+$ in the ALN, PBMCs and dorsal skin, IL-5, IL-13 in the dorsal skin by Real-time PCR and the distribution of mast cells by H&E and toluidine blue. Results In vitro the mRNA expression of IL-4, IL-5, IL-6, IL-13, TNF-${\alpha}$, GM-CSF and IL-13, MIP-$1{\alpha}$ production by ELISA analysis were completely abolished by DRC and the western blot analysis decreased the expression of mast cell-specific transcription factors including NFAT-1, NF-${\kappa}B$ p65. In vivo DRC oral adminstration also decreased the counts of WBC, eosinophils and inflammatory cytokines such as IL-13 and IgE in the serum. DRC oral adminstration elevated IL-4 level in the spleenocyte culture supernatant. DRC oral adminstration decreased total ALN cells, total skin cells, cell numbers of $CD4^+$, $B220^+CD23^+$ in the ALN, $^+Gr-1^+CD11b$ in the PBMCs and $CD4^+$, $CD8^+$ in the dorsal skin. The mRNA expression of IL-5, IL-13, thickness of epidermis, inflammation immune cells and mast cells were abolished by DRC in the dorsal skin. Conclusions Histological examination showed that infiltration levels of immune cells in the skin of AD-induced NC/Nga mouse were much improved by DRC oral adminstration. These results, therefore, suggest that DRC can regulate molecular mediators and immune cells that are functionally associated with atopic dermatitis induced in NC/Nga mouse, and may play an important role in recovering AD symptoms.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.4
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• pp.29-59
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• 2016

Objectives PRAL (Prunus armeniaca Linne Var) has been known to suppress allergic reaction. However, the cellular target and its mechanism of action were unclear. This study was designed to investigate the effect of PRAL on RBL-2H3 mast cell, which is PMA-Ionomycin-induced activated in vitro and the effect of PRAL on the MNC/Nga mice that are DNCB-induced activated in vivo. Methods In this study, IL-4, IL-13 production were examined by ELISA analysis; IL-4, IL-13, IL-31, IL-31Ra, $TNF-{\alpha}$ and GM-CSF mRNA expression were examined by Real-time PCR; manifestations of AP-1 and MAPKs transcription factors were examined by western blotting in vitro. Then skin rashes have been evaluated and verified the distribution of mast cells by H&E and toluidine blue. Also, WBC, eosinophil and neutrophil, IgE level in serum, $IFN-{\gamma}$, IL-4, IL-5 in the splenocyte culture supernatant, the absolute cell numbers of $CD4^+$, $CD8^+$, $Gr-1^+CD11b^+$, $B220^+CD23^+$, $CD3^+CD69^+$ in the Axillary Lymph Node (ALN), PBMCs and dorsal skin and IL-5, IL-13, IL-31, IL-31Ra in the dorsal skin by Real-time PCR were all evaluated from the NC/BNga mice. Results As a result of this study, the mRNA expression of IL-4, IL-13, IL-31, IL-31Ra and $TNF-{\alpha}$ and IL-4, IL-13 production, shown in ELISA analysis, were suppressed by PRAL. Results from the western blot analysis showed decrease on the expression of mast-cell-specific transcription factors, including AP-1 and p-JNK, p-ERK. Histological examination showed that infiltration levels of immune cells in the skin of the AD-induced NC/Nga mice were improved by PRAL orally adminstration. Orally- administered PRAL group also showred decreased level of IgE in the serum. This group has shown decreased the level of IL-4, IL-5, but shown elevated $IFN-{\gamma}$ level in the splenocyte culture supernatant. The same group also has shown decreased cell numbers of $CD4^+$, $CD8^+$, $CD3^+CD69^+$ in the ALN, and $CD4^+$, $Gr-1^+CD11b^+$ in the dorsal skin. PRAL oral adminstration increased cell numbers of $CD4^+$, but decreased cell numbers of $CD8^+$, $Gr-1^+CD11b^+$, $B220^+CD23^+$ in the PBMCs. Conclusions Obtained results suggest that PRAL can regulate molecular mediators and immune cells that are functionally associated with atopic dermatitis (AD) induced in the NC/Nga mice. This may play an important role in recovering AD symptoms and suppressing pruritus.

• Fire Science and Engineering
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• v.24 no.5
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• pp.142-149
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• 2010

The aim of this study was to report the out-of-hospital resuscitation of cardiac arrest along with literature consideration. CPR is technology of resuscitating patient by maintaining oxygen supply to organ, by preventing progression from clinical death to biological death, and by recovering heart beat and circulation, through circulatory support of mechanical ventilation. It is not what every patient with cardiac standstill is revived even if being implemented CPR. Patient's survival rate is decided by how quickly and correctly CPR was executed. A patient, who wasn't witnessed the cardiac arrest on the field, was performed 5-cycle CPR for 2 minutes on the field before being transferred to hospital, and was allowed to be used AED. A person, who was observed, is recommended to be used AED immediately, and then is said to be needed ACLS (advanced cardiac life support). In the Out-of-Hospital stage, it is rare in a case that 119 Emergency Medical Service System transfers by being ROSC and in a case of executing ACLS. Cardiac arrest was witnessed on the field, but CPR wasn't executed. First-aid staff executed CPR after arriving, and led to ROSC on the field with ACLS, there by having experienced 1 case of a patient's surviving to leave hospital by being ROSC on the field.

• Korean Journal of Childcare and Education
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• v.8 no.1
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• pp.145-167
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• 2012

The objective of this study is to investigate the meaning of pre-service educare teachers' experience about child safety management classes based on Problem Based Learning (PBL). The participants in this study were thirty five sophomores majoring in Social Welfare, and fifteen weeks of data were collected. The participants were given five problems that were related with real situations. During the given period, they made documents from reflective journals, group or individual interviews, and online community resources. Analyzing the documents sheds light on the meaning of the pre-service educare teachers' experience. The results are as follows: First, pre-service educare teachers found themselves recovering confidence, earning recognitions from others, and pursuing their study. Second, they showed continuous conflicts not only with the PBL approach but also with themselves and group members. Finally, they experienced mutual help and interactions among the group members thorough their cooperative learning and they realized the meaning of cooperative learning by means of comparisons and references between the groups. In conclusion, this study confirms the applicability of PBL to the educare teacher training courses and points out specific ways to alleviate the conflicts in applying PBL to class needs in future studies.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.40 no.5
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• pp.378-387
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• 2003

Digital watermarking is the technique that embeds invisible signalsincluding owner identification information, specific code, or pattern into multimedia data such as image, video and audio. Watermarking techniques can be classified into two groups; robust watermarking and fragile(semi-fragile) watermarking. The main purpose of the robust watermarking is the protection of copyright, whereas fragile(semi-fragile) watermarking prevents image or video data from illegal modifications. To achieve this goal watermark should survive from unintentional modifications such as random noise or compression, but it should be fragile for malicious manipulations. In this paper, an invertible semi-fragile watermarkingalgorithm for authentication and detection of manipulated location in MPEG-2 bit-stream is proposed. The proposed algorithm embeds two kinds of watermarks, which are embedded into quantized DCT coefficients. So it can be applied directly to the compressed bit-stream. The first watermark is used for authentication of video data. The second one is used for detection of malicious manipulations. It can distinguish transcodingin bit-stream domain from malicious manipulation and detect the block-wise locations of manipulations in video data. Also, since the proposed algorithm has an invertible property, recovering original video data is possible if the watermarked video is authentic.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.49 no.4
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• pp.49-57
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• 2012

This paper presents a fast multiple-image-based deblurring method that decreases the computation loads in the image deblurring, enhancing the sharpness of the textures or edges of the restored images. First, two blurred images with some blurring artifacts and one noisy image including severe noises are consecutively captured under a relatively long and short exposures, respectively. To improve the processing speeds, the captured multiple images are downsampled at the ratio of two, and then a way of estimating the point spread function(PSF) based on the image or edge patches extracted from the whole images, is introduced. The method enables to effectively reduce the computation time taken in the PSF prediction. Next, the texture-enhanced image deblurring method of supplementing the ability of the texture representation degraded by the downsampling of the input images, is developed and then applied. Finally, to get the same image size as the original input images, an upsampling method of utilizing the sharp edges of the captured noisy image is applied. By using the proposed method, the processing times taken in the image deblurring, which is the main obstacle of its application to the digital cameras, can be shortened, while recovering the fine details of the textures or edge components.

• Journal of Ginseng Research
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• v.28 no.2
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• pp.104-110
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• 2004

The aim of this study was to evaluate prospectively the impact of the red ginseng extract on circulating interleukin (IL) 2 and 10 in advanced gastric cancer during chemotherapy after operative treatment. Analysis of circulating IL-2 and 10 was performed in 50 patients with advanced gastric adenocarcinoma who underwent a curative surgery or with an unresectable gastric adenocarcinoma by using ELISA and monoclonal antibodies at preoperative day 1, postoperative months 1, and 3. Twenty-five patients as the control group, twenty-six patients as the non-ginseng (NG) group, and twenty-four patients as the ginseng (G) group were eligible in this study. All plasma IL-2 of the NG and G groups was significantly lower an that of the control group on preoperative 1 day. These values of the G group were more increase than these of the NG group during the postoperative chemotherapy. The mean value of serum IL-10 of the control group (0.608pg/ml) was significantly lower than that of the advanced gastric cancer patients including the NG (12.015 pg/ml) and G group (9.409 pg/ml) (p＜0.001). These values of the G group were reduced progressively during the postoperative chemotherapy. The mesh value of the G group were only close to that of the control group on postoperative months 3 (p=0.003). The number of patients who were enrolled in this study was relatively small to fully evaluate the immunologic effects of the red ginseng extract on circulating IL-2 and 10. Despite this limitation, these results suggest that the post-operative intake of the red ginseng extract have potential to improve earlier anti-cancer immunity with recovering IL-2 and reducing IL-10 from the depressed IL-2 and elevated IL-10 by gastric cancer during the postoperative chemotherapy. This study will be based on the future study to evaluate the anti-immunity of the red ginseng extract.