• BMB Reports
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• 제45권12호
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• pp.736-741
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• 2012

Certain members of the cytochromes P450 superfamily metabolize polyunsaturated long-chain fatty acids to several classes of oxygenated metabolites. An approach based on in silico analysis predicted that Streptomyces peucetius CYP107N3 might be a fatty acid-metabolizing enzyme, showing high homology with epoxidase enzymes. Homology modeling and docking studies of CYP107N3 showed that oleic acid can fit directly into the active site pocket of the double bond of oleic acid within optimum distance of $4.6{\AA}$ from the Fe. In order to confirm the epoxidation activity proposed by in silico analysis, a gene coding CYP107N3 was expressed in Escherichia coli. The purified CYP107N3 was shown to catalyze $C_9-C_{10}$ epoxidation of oleic acid in vitro to 9,10-epoxy stearic acid confirmed by ESI-MS, HPLC-MS and GC-MS spectral analysis.

• Journal of Gastric Cancer
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• 제22권2호
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• pp.83-93
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• 2022

Background: To analyze the short- and long-term clinical outcomes of 2 reconstruction methods after distal gastrectomy for gastric cancer. Methods: Three keywords, "gastric neoplasm," "distal gastrectomy," and "reconstruction," were used to search PubMed. We selected only randomized controlled trial that compared the anastomosis methods. A total of 11 papers and 8 studies were included in this meta-analysis. All statistical analyses were performed using the R software. Results: Among short-term clinical outcomes, a shorter operation time, reduced morbidity, and shorter hospital stay were found for Billroth type I (B-I) than for Roux-en-Y (RNY) reconstruction in the meta-analysis (P<0.001, P=0.048, P<0.001, respectively). When comparing Billroth type II (B-II) to RNY, the operation time was shorter for B-II than for RNY (P<0.019), but there were no differences in morbidity or length of hospital stay (P=0.500, P=0.259, respectively).Regarding long-term clinical outcomes related to reflux, there were significantly fewer incidents of reflux esophagitis, reflux gastritis, and bile reflux (P=0.035, P<0.001, P=0.019, respectively) for RNY than for B-I in the meta-analysis, but there was no difference between the 2 methods in residual food (P=0.545). When comparing B-II to RNY, there were significantly fewer incidents of reflux gastritis (P<0.001) for RNY than for B-II, but the amount of residual food and patient weight gain showed no difference. Conclusion: B-I had the most favorable short-term outcomes, but RNY was more advantageous for long-term outcomes than for other methods. Surgeons should be aware of the advantages and disadvantages of each type of anastomosis and select the appropriate method.

• Hip & pelvis
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• 제36권3호
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• pp.168-178
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• 2024

The purpose of this meta-analysis is to compare the postoperative outcomes and complications of labral repair with those of labral reconstruction. An electronic search strategy was conducted from 1986 until August 2023 using the following databases: PubMed, Cochrane, and Google Scholar (pages 1-20). The primary objectives included the postoperative clinical outcomes determined by the number of patients who reached minimal clinical important difference (MCID) on the visual analog scale (VAS), modified Harris hip score (mHHS), Hip Outcome Score-Sports Subscale (HOS-SS), Hip Outcome Score-Activities of Daily Life (HOS-ADL), and International Hip Outcome Tool-12 (iHOT-12). In addition, analysis of the rate of revision arthroscopy, the rate of conversion to total hip arthroplasty (THA), the postoperative VAS, mHHS, HOS-SS, HOS-ADL, iHOT-12, nonarthritic hip score (NAHS), patient satisfaction, lower extremity function scale (LEFS), and the SF-12 (12-item shortform) was also performed. Any differences arising between the investigators were resolved by discussion. Seventeen studies were relevant to the inclusion criteria and were included in this meta-analysis. A higher rate of patients who reached MCID in the mHHS (P=0.02) as well as a higher rate of revision arthroscopy was observed for labral repair (P=0.03). The remaining studied outcomes were comparable. Despite the greater predictability of success in the reconstruction group, conduct of additional studies will be required for evaluation of the benefits of such findings. In addition, labral reconstruction is more technically demanding than a labral repair.

• Journal of the Optical Society of Korea
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• 제12권2호
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• pp.88-92
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• 2008

This paper discusses a photon-counting linear discriminant analysis (LDA) with computational integral imaging (II). The computational II method reconstructs three-dimensional (3D) objects on the reconstruction planes located at arbitrary depth-levels. A maximum likelihood estimation (MLE) can be used to estimate the Poisson parameters of photon counts in the reconstruction space. The photon-counting LDA combined with the computational II method is developed in order to classify partially occluded objects with photon-limited images. Unknown targets are classified with the estimated Poisson parameters while reconstructed irradiance images are trained. It is shown that a low number of photons are sufficient to classify occluded objects with the proposed method.

• Industrial Engineering and Management Systems
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• 제4권1호
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• pp.102-108
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• 2005

This paper studies medical data classification methods, comparing decision tree and system reconstruction analysis as applied to heart disease medical data mining. The data we study is collected from patients with coronary heart disease. It has 1,723 records of 71 attributes each. We use the system-reconstruction method to weight it. We use decision tree algorithms, such as induction of decision trees (ID3), classification and regression tree (C4.5), classification and regression tree (CART), Chi-square automatic interaction detector (CHAID), and exhausted CHAID. We use the results to compare the correction rate, leaf number, and tree depth of different decision-tree algorithms. According to the experiments, we know that weighted data can improve the correction rate of coronary heart disease data but has little effect on the tree depth and leaf number.

• Journal of Information Processing Systems
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• 제19권3호
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• pp.323-333
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• 2023

Facial expression recognition can aid in the development of fatigue driving detection, teaching quality evaluation, and other fields. In this study, a facial expression recognition method was proposed with a residual masking reconstruction network as its backbone to achieve more efficient expression recognition and classification. The residual layer was used to acquire and capture the information features of the input image, and the masking layer was used for the weight coefficients corresponding to different information features to achieve accurate and effective image analysis for images of different sizes. To further improve the performance of expression analysis, the loss function of the model is optimized from two aspects, feature dimension and data dimension, to enhance the accurate mapping relationship between facial features and emotional labels. The simulation results show that the ROC of the proposed method was maintained above 0.9995, which can accurately distinguish different expressions. The precision was 75.98%, indicating excellent performance of the facial expression recognition model.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(5)
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• pp.9-12
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• 2002

The problem of sub-Nyquist nonuniform sampling for the perfect reconstruction of signals with time-varying spectral contents is studied. The signals are assumed to have a known instantaneous bandwidth in time-frequency domain. As the function of time, the nonuniform sampling pattern of a given signal, that is, the instantaneous sampling frequency is determined by the observation of instantaneous bandwidth based on time-frequency analysis. The proposed sampling pattern guarantees the perfect reconstruction of nonuniform sampled signals under Nyquist-sampling rate in average.

• 대한의용생체공학회:의공학회지
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• 제11권1호
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• pp.89-96
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• 1990

The numerical evaluation of Rayleigh's integral for the sound source reconstruction can be speeded up by the use of angular frequency propagation method and the FFT. However, are several source of errors involved during the reconstruction. Besides the aliasing error due to undersampling in space, the wrap around error. which is caused by undersampling the kernel functionin frequency domain, and windowing effect are present. We found that there is no replicated source problem and the windowing effect is due to the windowing the kernel function In frequency domain, and, xero padding is always required to improve the quality of reconstruction.

• 대한두개안면성형외과학회지
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• 제21권4호
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• pp.237-243
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• 2020

Background: The scalp is an important functional and aesthetic structure that protects the cranial bone. Due to its inelastic characteristics, soft-tissue defects of the scalp make reconstruction surgery difficult. This study aims to provide an improved scalp reconstruction decision making algorithm for surgeons. Methods: This study examined patients who underwent scalp reconstruction within the last 10 years. The study evaluated several factors that surgeons use to select a given reconstruction method such as etiology, defect location, size, depth, and complications. An algorithmic approach was then suggested based on an analysis of these factors. Results: Ninety-four patients were selected in total and 98 cases, including revision surgery, were performed for scalp reconstruction. Scalp reconstruction was performed by primary closure (36.73%), skin graft (27.55%), local flap (17.34%), pedicled regional flap (15.30%), and free flap (3.06%). The ratio of primary closure to more complex procedure on loose scalps (51.11%) was significantly higher than on tight scalps (24.52%) (p=0.011). The choice of scalp reconstruction method was affected significantly by the defect size (R=0.479, p<0.001) and depth (p<0.001). There were five major complications which were three cases of flap necrosis and two cases of skin necrosis. Hematoma was the most common of the 29 minor complications reported, followed by skin necrosis. Conclusion: There are multiple factors affecting the choice of scalp reconstruction method. We suggest an algorithm based on 10 years of experience that will help surgeons establish successful surgical management for their patients.

• Archives of Plastic Surgery
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• 제50권4호
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• pp.361-369
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• 2023

The latissimus dorsi (LD) flap is a reliable option for breast reconstruction. This is particularly true in patients with contraindications to abdominally based autologous breast reconstruction. A systematic review of patient satisfaction and health related quality of life following LD breast reconstruction using the BREAST-Q survey was conducted. The scope of the review was to determine the degree of patient satisfaction following the procedure and to examine how patient satisfaction from the pedicled LD flap compares to other breast reconstructive procedures. A literature search on BREAST-Q in LD flap reconstruction was performed. Only articles written in English and in published peer-reviewed journals were included. Studies with less than 20 patients in their sample and those with a follow-up period of less than 1 year were excluded. Five articles representing 331 patients were reviewed, including one case-control study and four retrospective cohort studies. Level of evidence was either III (4) or IV (1). The average age was 53 with average body mass index of 25. Most reconstructions were delayed (67%) and unilateral (88%), and most patients required radiation (79%). The average length of follow-up was 36 months, and the response rate was 75%. Overall, patients who underwent LD flap reconstruction reported favorable outcomes in satisfaction domains and quality of life domains with few complications. A meta-analysis also demonstrated higher satisfaction in LD flap without implants compared with LD flap with implants. Patient-reported outcomes following LD breast reconstruction compare favorably with other techniques of breast reconstruction.