• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 추계학술대회
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• pp.470-473
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• 2018

고차변조방식을 사용하는 광대역 시스템은 무선채널환경의 변화뿐만 아니라 baseband 신호가 RF 장비를 통과하면서 발생할 수 있는 평탄도(Ripple) 특성 변화에 민감하다. 따라서 평탄도 특성 변화를 최소화 할 수 있는 설계와 RF 튜닝이 필요하지만 시스템 구현이 어렵고 많은 시간이 소요된다. 본 논문에서는 baseband 신호가 RF 송수신 장비를 거치면서 왜곡되는 고정적인 평탄도 특성을 분석하여 보상 필터의 계수(Coefficient) 값을 추출하고 수신부에서 보상 필터로 보상을 하는 기능을 256TCM(Trellis Coded Modulation) 방식으로 구현하였다. 또한 시스템에 적용하여 시험한 결과 RF 송수신 장비의 평탄도 특성이 좋지 않은 주파수대역에서 디지털 보상필터를 적용하여 SNR 및 수신감도의 개선이 있음을 확인하였다.

• 한국통신학회논문지
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• 제32권5C호
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• pp.469-477
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• 2007

소스 코딩을 통해 얻어지는 대다수의 멀티미디어 데이터 정보는 여러 등급의 다른 비트에러민감도를 가지고 있다. 그러므로 효율적인 시스템 구현을 위해서는 데이터 고유의 비트에러민감도에 따라 서로 다른 수준의 에러 방지를 제공해야 한다. 이 논문에서는 다중안테나 (multiple-in multiple-out : MIMO) 기반의 OFDM시스템에서 효과적인 멀티미디어 정보를 전송하기 위한 차등 에러 방지 기법(Unequal error protection : UEP)을 제안한다. 차등의 에러 방지를 제공하는 시공간 코딩 기법을 설명하고 그 성능을 평가한다. MIMO 기법과 BICM (Bit-interleaved coded modulations) 기술은 보통 RCPC (Rate compatible punctured convolutional codes) 기법과 연계되어 구동된다. 이때 다중안테나 채널 이퀄라이저와 채널코딩 사이에 터보디코딩 기법을 적용하여 최상의 성능을 얻을 수 있는데 기존의 시스템에서는 동일한 에러방지기법(Equal Error Protection : EEP)을 사용하고 있다. 이 논문에서는 이런 시스템 구조에서 보통 사용되는 동일 에러 방지 기법(EEP)와 비교하여 차등 에러방지 기법(UEP)를 사용함으로써 얻을 수 있는 이득을 사용되는 전송파워와 채널밴드 측면에서 설명한다. 특히 제안된 알고리즘을 둘 또는 세 개의 전송 안테나와 두 개의 수신안테나를 갖는 다중안테나 시스템에 적용하고 8PSK 신호를 이용하여 플랫 페이딩 채널에서 성능을 평가하였다.

• Journal of Communications and Networks
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• 제15권4호
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• pp.383-397
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• 2013

In this paper, the sensitivity of massive antenna arrays and digital beamforming to radio frequency (RF) chain in-phase quadrature-phase (I/Q) imbalance is studied and analyzed. The analysis shows that massive antenna arrays are increasingly sensitive to such RF chain imperfections, corrupting heavily the radiation pattern and beamforming capabilities. Motivated by this, novel RF-aware digital beamforming methods are then developed for automatically suppressing the unwanted effects of the RF I/Q imbalance without separate calibration loops in all individual receiver branches. More specifically, the paper covers closed-form analysis for signal processing properties as well as the associated radiation and beamforming properties of massive antenna arrays under both systematic and random RF I/Q imbalances. All analysis and derivations in this paper assume ideal signals to be circular. The well-known minimum variance distortionless response (MVDR) beamformer and a widely-linear (WL) extension of it, called WL-MVDR, are analyzed in detail from the RF imperfection perspective, in terms of interference attenuation and beamsteering. The optimum RF-aware WL-MVDR beamforming solution is formulated and shown to efficiently suppress the RF imperfections. Based on the obtained results, the developed solutions and in particular the RF-aware WL-MVDR method can provide efficient beamsteering and interference suppressing characteristics, despite of the imperfections in the RF circuits. This is seen critical especially in the massive antenna array context where the cost-efficiency of individual RF chains is emphasized.

• Genomics & Informatics
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• 제13권3호
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• pp.70-75
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• 2015

MicroRNAs (miRNAs) have been demonstrated to play an important role in carcinogenesis. Previous studies revealed that miRNAs are present in human plasma in a remarkably stable form that is protected from endogenous RNase activity. In this study, we measured the plasma expression levels of three miRNAs (miR-21, miR-27a, and miR-155) to investigate the usefulness of miRNAs for gastric cancer detection. We initially examined plasma miRNA expression levels in a screening cohort consisting of 15 patients with gastric cancer and 15 healthy controls from Korean population, using TaqMan quantitative real-time polymerase chain reaction. We observed that the expression level of miR-27a was significantly higher in patients with gastric cancer than in healthy controls, whereas the miR-21 and miR-155a expression levels were not significantly higher in the patients with gastric cancer. Therefore, we further validated the miR-27a expression level in 73 paired gastric cancer tissues and in a validation plasma cohort from 35 patients with gastric cancer and 35 healthy controls. In both the gastric cancer tissues and the validation plasma cohort, the miR-27a expression levels were significantly higher in patients with gastric cancer. Receiver-operator characteristic (ROC) analysis of the validation cohort, revealed an area under the ROC curve value of 0.70 with 75% sensitivity and 56% specificity in discriminating gastric cancer. Thus, the miR-27a expression level in plasma could be a useful biomarker for the diagnosis and/or prognosis of gastric cancer.

• 생물정신의학
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• 제16권2호
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• pp.112-120
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• 2009

Objectives : Depression is a common psychiatric disorder in cancer patients. The Brief Edinburgh Depression Scale(BEDS), which is an abbreviated version of the Edinburgh Depression Scale, may serve as a useful tool in screening for the depression in patients with the medical illnesses. This report investigated the reliability and validity of the Korean Version of the BEDS(K-BEDS) for the depression in cancer patients. Methods : One-hundred cancer patients were enrolled in this study. All subjects completed the K-BEDS, the Hospital Anxiety Depression Scale(HADS), and the Karnofsky Performance Status Scale(KPSS). Reliability, validity and Receiver Operating Characteristic(ROC) curve analysis measures were assessed. Results : The K-BEDS showed good internal consistency(Cronbach ${\alpha}$=0.77) and test-retest reliability(0.94, p<0.001). All item-total correlations were above 0.3. Also, it revealed moderate correlation with the depression subscale of the HADS(r=0.617), but no correlation with the KPSS. Exploratory factor analysis produced only one factor, accounting for 47.1% of the total variance. The most valid cutoff value to screen for depression was a total score of 5 on the K-BEDS, which showed sensitivity of 62.5% and specificity of 86.4% with a positive predictive value of 4.60 and a negative predictive value of 0.43.

• IEIE Transactions on Smart Processing and Computing
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• 제4권4호
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• pp.195-201
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• 2015

For median filtering (MF) detection in altered digital images, this paper presents a new feature vector that is formed from autoregressive (AR) coefficients via an AR model of the gradients between the neighboring row and column lines in an image. Subsequently, the defined 10-D feature vector is trained in a support vector machine (SVM) for MF detection among forged images. The MF classification is compared to the median filter residual (MFR) scheme that had the same 10-D feature vector. In the experiment, three kinds of test items are area under receiver operating characteristic (ROC) curve (AUC), classification ratio, and minimal average decision error. The performance is excellent for unaltered (ORI) or once-altered images, such as $3{\times}3$ average filtering (AVE3), QF=90 JPEG (JPG90), 90% down, and 110% up to scale (DN0.9 and Up1.1) images, versus $3{\times}3$ and $5{\times}5$ median filtering (MF3 and MF5, respectively) and MF3 and MF5 composite images (MF35). When the forged image was post-altered with AVE3, DN0.9, UP1.1 and JPG70 after MF3, MF5 and MF35, the performance of the proposed scheme is lower than the MFR scheme. In particular, the feature vector in this paper has a superior classification ratio compared to AVE3. However, in the measured performances with unaltered, once-altered and post-altered images versus MF3, MF5 and MF35, the resultant AUC by 'sensitivity' (TP: true positive rate) and '1-specificity' (FN: false negative rate) is achieved closer to 1. Thus, it is confirmed that the grade evaluation of the proposed scheme can be rated as 'Excellent (A)'.

• 전기전자학회논문지
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• 제21권4호
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• pp.338-347
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• 2017

본 논문은 TDL(전술 데이터 링크)의 항공용 단말의 구성품인 고출력증폭기의 설계 및 제작에 관해 기술하였다. 동일한 주파수 대역을 사용하는 레이다 및 다른 통신장비와 한정된 주파수 자원을 효율적 사용이 가능하도록 고속주파수도약기술, 인지무선기술, 수신필터뱅크 기술을 적용하였다. 고출력증폭기는 물리적으로 송신부, 수신부, 기구부, 케이블조립체로 구성되며, 최대 전송 거리, 수신감도 등의 전기적 특성과 온도 특성을 충족하도록 설계되었다. 고출력증폭기의 요구 규격을 만족하기 위해 모델링 및 시뮬레이터를 이용하였다. 송신 출력과 잡음 지수는 각각 50.02dBm 및 2.682dB로 측정되었다. 전기적 특성 시험 및 환경 특성 시험으로 요구 규격을 모두 만족함을 확인하였다.

• Clinical and Experimental Reproductive Medicine
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• 제47권1호
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• pp.61-67
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• 2020

Objective: In this study, specimens from testicular biopsies of men with nonobstructive azoospermia (NOA) were used to investigate whether RNF8 gene could serve as a biomarker to predict the presence of sperm in these patients. Methods: Testicular biopsy specimens from 47 patients were classified according to the presence of sperm (positive vs. negative groups) and investigated for the expression of RNF8. The level of RNF8 gene expression in the testes was compared between these groups using reverse-transcription polymerase chain reaction. Results: The expression level of RNF8 was significantly higher in testicular samples from the positive group than in those from the negative group. Moreover, the area under the curve of RNF8 expression for the entire study population was 0.84, showing the discriminatory power of RNF8 expression in differentiating between the positive and negative groups of men with NOA. A receiver operating characteristic curve analysis showed that RNF8 expression had a sensitivity of 81% and a specificity of 84%, with a cutoff level of 1.76. Conclusion: This study points out a significant association between the expression of RNF8 and the presence of sperm in NOA patients, which suggests that quantified RNF8 expression in testicular biopsy samples may be a valuable biomarker for predicting the presence of spermatozoa in biopsy samples.

• Archives of Plastic Surgery
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• 제37권4호
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• pp.346-350
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• 2010

Purpose: Diagnosis of diabetic foot infection is sometimes difficult, since the classical inflammatory signs and leukocytosis may be absent due to the decreased host immune response in diabetics. Therefore inflammatory blood markers, such as white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) have been commonly needed to confirm the diagnosis of infection. The purpose of this study is to evaluate the diagnostic usefulness of WBC, ESR and CRP for detection of diabetic foot infection. Methods: Peripheral blood samples were taken from 113 patients with diabetic foot ulcers admitted from June 2007 to April 2009. Diabetic foot infection was diagnosed according to the microbiological culture from soft tissue and bone specimens. Reference values of tests were 4500-11000 /${\mu}L$ for WBC count, 0-20 mm/hr for ESR, and 0-5 mg/L for $CRP^{13,14}$. Sensitivities, specificities, positive and negative predictive values of laboratory tests were calculated and analysed. Receiver-operator characteristic (ROC) curve was also created. Results: There was a significant difference in WBC, ESR, and CRP between infectious group and noninfectious group (p<0.05). The sensitivity of WBC>11,000 /${\mu}L$ ESR > 20 mm/hr, and CRP > 5 mg/L was 30%, 96%, and 84%. The specificity was 86%, 14%, and 50% for WBC, ESR, and CRP, respectively. Positive predictive value was 88%, 78%, and 84%, and negative predictive value was 28%, 50%, and 50% respectively. The areas under the ROC curve for WBC, ESR and CRP were 0.72, 0.75, and 0.78 respectively. Conclusion: Based on the results of this study, we conclude that CRP is more useful method in predicting and diagnosing infection than WBC, ESR in diabetic foot ulcer patients.

• Journal of Korean Neurosurgical Society
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• 제60권5호
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• pp.550-559
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• 2017

Objective : Subsidence is a frequent complication of anterior cervical discectomy and fusion. Postoperative segmental micromotion, thought to be a causative factor of subsidence, has been speculated to increase with uncinate process resection area (UPR). To evaluate the effect of UPR on micro-motion, we designed a method to measure UPR area based on pre- and postoperative computed tomography images and analyzed the relationship between UPR and subsidence as a proxy of micro-motion. Methods : We retrospectively collected clinical and radiological data from January 2011 to June 2016. A total of 38 patients (53 segments) were included. All procedures included bilateral UPR and anterior plate fixation. UPR area was evaluated with reformatted coronal computer tomography images. To reduce level-related bias, we converted UPR area to the proportion of UPR to the pre-operative UP area (pUPR). Results : Subsidence occurred in 18 segments (34%) and positively correlated with right-side pUPR, left-side pUPR, and the sum of bilateral pUPR (sum pUPR) (R=0.310, 301, 364; p=0.024, 0.029, 0.007, respectively). Multiple linear regression analysis revealed that subsidence could be estimated with the following formula : $subsidence=1.522+2.7{\times}sum\;pUPR$($R^2=0.133$, p=0.007). Receiver-operating characteristic analysis determined that sum $pUPR{\geq}0.38$ could serve as a threshold for significantly increased risk of subsidence (p=0.005, area under curve=0.737, sensitivity=94%, specificity=51%). This threshold was confirmed by logistic regression analysis for subsidence (p=0.009, odds ratio=8.471). Conclusion : The UPR measurement method confirmed that UPR was correlated with subsidence. Particularly when the sum of pUPR is ${\geq}38%$, the possibility of subsidence increased.