• Journal of Microbiology and Biotechnology
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• v.20 no.9
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• pp.1314-1321
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• 2010

Sulfur metabolism in S. cerevisiae is well established, but the mechanisms underlying the formation of sulfide remain obscure. Here, we investigated by real-time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16, and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles. MET3 was the most highly expressed of the genes studied in strain PYCC4072, and SSU1 in strain UCD522. The strains behaved differently according to the sampling times, with UCD522 and PYCC4072 showing the highest expression levels at 120 h and 72 h, respectively. In the presence of 267 mg assimilable N/l, the genes were more highly expressed in strain UCD522 than in PYCC4072. MET5/ECM17 and MET17 were only weakly expressed in both strains under any condition tested. MET10 and SSU1 in both strains, but MET16 only in PYCC4072, were consistently upregulated when sulfide production was inhibited. This study illustrates that strain genotype could be important in determining enzyme activities and therefore the rate of sulfide liberation. This linkage, for some yeast strains, of sulfide production to expression levels of genes associated with sulfate assimilation and sulfur amino acid biosynthesis could be relevant for defining new strategies for the genetic improvement of wine yeasts.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10917-10922
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• 2015

Background: This study was conducted to determine DEPDC1 expression in hepatocelluar carcinomas (HCCs) and to reveal its potential role in diagnosis and prognosis of affected patients. Materials and Methods: DEPDC1 expression at the mRNA level was detected by quantitative real-time PCR (qRT-PCR) in 205 cases of HCC and paired adjacent normal liver tissues, and by semi-quantitative RT-PCR in 20 cases. Survival curves were obtained by using Kaplan-Meier method and Log-rank test. Independent predictors associated with regard to disease free survival (DFS) and overall survival (OS) were identified using the Cox proportional hazard model. Results: High DEPDC1 mRNA levels were detected in 144 out of 205 cases (70.24%) of HCC, significantly associated with clinicopathological parameters, including tumor size (${\geq}4cm$), alpha-fetoprotein (${\geq}100ng/ml$), B-C of BCLC stage and recurrence. Kaplan-Meier survival analysis revealed that HCC patients with high DEPDC1 expression had poor OS and DFS. Multivariate analysis demonstrated that high DEPDC1 expression was an independent predictor for OS (HR=1.651; 95% 95%CI, 1.041-2.617; p=0.033) and DFS (HR=1.583; 95%CI, 1.01-2.483; p=0.045). Conclusions: Our results indicate DEPDC1 might be a novel diagnostic marker and an independent prognostic predictor for HCC patients.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.701-705
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• 2013

Polymorphisms in XPG are considered to contribute to the clinical outcome of patients receiving platinum drug chemotherapy. We aimed to investigate the role of five potential SNPs of XPG gene on the response to platinum-based chemotherapy in advanced Chinese NSCLC patients. A total of 451 patients with newly diagnosed and histopathologically confirmed primary NSCLC were consecutively collected. XPG rs2296147, rs4150261, rs17655, rs1047768 and rs2094258 were genotyped by the Taqman real-time polymerase chain reaction (PCR). In our study, we found patients carrying rs1057768 TT genotype had a significantly lower treatment response when compared with the CC genotype (OR=0.38, 95% CI=0.18-0.78). Patients carrying rs1047768 TT genotype showed a significantly short median PFS (11.2 months) and OS (13.6 months) than CC genotype, and the hazard ratios (HR) for PFS and OS were 2.06 (1.01-4.50) and 2.29 (1.21-2.49), respectively. Moreover, we found a significant decreased risk of death from NSCLC among patients carrying the rs2296147 TT genotype when compared with the CC genotype, the HR (95% CI) for OS being 0.50 (0.27-0.95). In conclusion, our study found that polymorphisms in rs1047768 C/T and rs2296147 C/T are associated with response to platinum-based chemotherapy in advanced NSCLC, and XPG polymorphisms could be predictive of prognosis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.10B
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• pp.883-890
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• 2006

The study of sensor network database is beginning to liven up as we are interested in Ubiquitous Computing technology in hardware, communication, database and so on. Especially, as new smart sensors have capabilities of real-time information gathering and analysis of each sensor node, data processing becomes an important issue in Ubiquitous Computing. In thesis, we have applied TinyDB(query processing system) to carry sensor node with line tracer which can follow the fixed path. After we gathered data around path, we have processed data in TinyDB GUI, gathered data, displayed data on a web server. Also we have a web browser on an embedded board for convenient user interface and implemented touch screen such that users can operate with a finger.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.6
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• pp.1388-1393
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• 2007

The Microprocessor Based Laboratory Systems(MBL) with the remote access functional could put basic science experimental facilities together by providing a modem platform that the students can utilize simultaneously to learn basic physics, chemistry and biology, Our educator target platform combines a highly integrated 8-bit embedded Atmega128 processor and real time embedded OS (operating system), allowing plenty of headroom for follow-on basic science projects for students. The proposed MBL-NUTOS (Microprocessor Based Laboratory-NUT/OS) employed in the lab are available with internet base simulation capabilities, on public servers and students personal PCs, enabling the students to study at home and increasing the opportunity of accessing for the science laboratory facility.

• The KIPS Transactions:PartA
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• v.8A no.4
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• pp.429-438
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• 2001

GPS (Global Positioning System) is the most ideal navigation system which can be used on the earth irrespective of time and weather conditions. GPS has been used for various applications such as construction, survey, environment, communication, intelligent vehicles and airplanes and the needs of GPS are increasing in these days. This paper deals with the design and implementation of the RTOS (Real-Time Operating System) for a GPS navigation computer in the GPS/INS integrated navigation system. The RTOS provides the optimal environment for execution and the base platform to develop GPS application programs. The key facilities supplied by the RTOS developed in this paper are priority-based preemptive scheduling policy, dynamic memory management, intelligent interrupt handling, timers and IPC, etc. We also verify the correct operations of all application tasks of the GPS navigation computer on the RTOS and evaluate the performance by measuring the overhead of using the RTOS services.

• The Journal of the Acoustical Society of Korea
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• v.21 no.3
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• pp.237-244
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• 2002

In this paper we mention the optimization of MPEG-4 VM (Moving Picture Expert Group-4 Verification Model) GA (General Audio) AAC (Advanced Audio Coding) encoder and the design of the decoder for PDA (Personal Digital Assistant) using MPEG-4 VM source. We profiled the VMC source and several optimization methods have applied to those selected functions from the profiling. Intel Pentium III 600 MHz PC, which uses windows 98 as OS, takes about 20 times of encoding time compared to input sample running time, with additional options, and about 10 times without any option. Decoding time on PDA was over 35 seconds for the 17 seconds input sample. After optimization, the encoding time has reduced to 50% and the real time decoding has achieved on PDA.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.28 no.6
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• pp.1489-1497
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• 2018

Web application services have diversified. At the same time, research on intrusion detection is continuing due to the surge of cyber threats. Also, As a single-defense system evolves into multi-level security, we are responding to specific intrusions by correlating security events that have become vast. However, it is difficult to check the OS, service, web application type and version of the target system in real time, and intrusion detection events occurring in network-based security devices can not confirm vulnerability of the target system and success of the attack A blind spot can occur for threats that are not analyzed for problems and associativity. In this paper, we propose the validation of effectiveness for intrusion detection events using TF-IDF. The proposed scheme extracts the response traffics by mapping the response of the target system corresponding to the attack. Then, Response traffics are divided into lines and weights each line with an TF-IDF weight. we checked the valid intrusion detection events by sequentially examining the lines with high weights.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.28 no.9
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• pp.99-104
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• 2014

This paper presents a unified live-streaming method based on Hypertext Mark-up Language 5(HTML5) for an IP camera which is independent of browsers of clients and is implemented with open-source libraries. Currently, conventional security systems based on analog CCTV cameras are being modified to newer surveillance systems utilizing IP cameras. These cameras offer remote surveillance and monitoring regardless of the device being used at any time, from any location. However, this approach needs live-streaming protocols to be implemented in order to verify real-time video streams and surveillance is possible after installation of separate plug-ins or special software. Recently, live streaming is being conducted through HTML5 using two different standard protocols: HLS and DASH, that works with Apple and Android products respectively. This paper proposes a live-streaming approach that is linked on either of the two protocols which makes the system independent with the browser or OS. The client is possible to monitor real-time video streams without the need of any additional plug-ins. Moreover, by implementing open source libraries, development costs and time were economized. We verified usefulness of the proposed approach through mobile devices and extendability to other various applications of the system.

• Journal of Korea Multimedia Society
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• v.6 no.1
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• pp.15-27
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• 2003

Recently, the volume of data is increasing rapidly in server for multimedia service, according to development of multimedia application environment. In recent research for storage technology the technology like of the SAN(Storage Area Network) advantages in scalibility of storage devices, and can read data from multiple disk arrays through RAID 0, 5. The RAID 0 and 5 translate to logical address to physical address using equation, but in case of adding disks at the system with equation -based mapping, the problem that we must rearrange the whole data in the previous disks happens. We use the mapping table to solve this problem in recent, but we can not load the whole mapping table in main memory because it occupies too large space. Therefore the extra I/Os are demanded to evaluate real physical address of data, so total performance of the system is degraded. In this paper, we propose the mapping method that supports the scalibility in RAID 0 or 5 system. The proposing method applies small metadata, so- called SZIT and simple equation, so it is possible that we make translate logical address to physical address rapidly and it is scalable in disk extending simultaneously Our suggesting method, if we add disks to the striping system for expanding of storage capacity, has an advantage of never stop service. So, SZlT-based mapping method can do online-disk-expanding in real-time service.