• Biomolecules & Therapeutics
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• 제11권4호
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• pp.224-231
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• 2003

The aim of this study was to investigate the effect of resveratrol on the oxidative stress-induced inhibition of gap junctional intercellular communication in HaCaT keratinocytes. Anti-oxidative activity of resveratrol was measured by $\alpha,\alpha$-diphenyl-$\beta$-picrylhydrazyl assay and dichlorodihydrofluorescein diacetate oxidation assay. Gap junctional intercellular communication in HaCaT keratinocytes was assessed using the scrape loading/dye transfer technique. Western blots and reverse transcription-polymerase chain reaction were also analyzed for connexin 43 protein and mRNA expression, respectively. Resveratrol scavenged directly the stable $\alpha,\alpha$-diphenyl-$\beta$-picrylhydrazyl radical over a concentration range of 4 mg/ml ($78.2{\pm}2.7$% of control) to 500 mg/ml ($29.9{\pm}4.2$% of control) and decreased the intracellular reactive oxygen species induced by ultraviolet A (UVA) irradiation ($89.3{\pm}1.1$% of UVA group), ultraviolet B (UVB) irradiation ($70.9{\pm}1.7$% of UVB group) and 12-0-tet-radecanoylphorbol-13-acetate (TPA, $48.3{\pm}1.1$% of TPA group), respectively. UVA irradiation and TPA markedly reduced gap junctional intercellular communication, which was restored by resveratrol. There were no significant differences in the level of connexin 43 protein and mRNA expression among any of the experimental groups. Our data suggests that resveratrol has the protective effect on the oxidative stress-induced inhibition of gap junctional intercellular communication in HaCaT keratinocytes, and this protection is likely due to the scavenging of reactive oxygen species.

• Nutrition Research and Practice
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• 제3권4호
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• pp.272-278
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• 2009

Postprandial hypoglycemic effect of mulberry leaf (Morus alba L.) was compared in two animal models: Goto-Kakizaki (GK) rats, a spontaneous non-obese animal model for type II diabetes, and their counterpart control Wistar rats. First, the effect of a single oral administration of mulberry leaf aqueous extract (MLE) on postprandial glucose responses was determined using maltose or glucose as substrate. With maltose-loading, MLE reduced peak responses of blood glucose significantly in both GK and Wistar rats (P < 0.05), supporting the inhibition of $\alpha$-glucosidase by MLE in the small intestine. With glucose-loading, MLE also significantly reduced blood glucose concentrations, measured at 30 min, in both animal models (P < 0.01), proposing the inhibition of glucose transport by MLE. Next, dried mulberry leaf powder (MLP) was administered for 8 weeks by inclusion in the diet. By MLP administration, fasting blood glucose was significantly reduced at weeks 4 and 5 (P < 0.05), but then returned to values that were similar to those of the control at the end of experimental period in GK rats. Insulin, HOMA-IR, C-reactive protein, and triglycerides tended to be decreased by MLP treatment in GK rats. All other biochemical parameters were not changed by MLP administration in GK rats. Collectively, these findings support that MLE has significant postprandial hypoglycemic effect in both non-obese diabetic and healthy animals, which may be beneficial as food supplement to manage postprandial blood glucose. Inhibitions of glucose transport as well as $\alpha$-glucosidase in the small intestine were suggested as possible mechanisms related with the postprandial hypoglycemic effect of MLE.

• Animal cells and systems
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• 제7권4호
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• pp.289-294
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• 2003

To quantify nutrient loading from emergent macrophytes through leaching in the littoral zones of Paldang Reservoir, we conducted incubation experiments using leaf litter of the emergent macrophyte, Zizaniz latifolia. To separate the leaching process from microbial decay, we used $HgCl_2$ to suppress microbial activity during the experiment. We measured electric conductivity, absorbance at 280nm, total nitrogen and dissolved inorganic nitrogen, total phosphorus and soluble reactive phosphorus, Na, K, Mg and Ca amounts in leaf litter and in water. In addition, we examined the effects of water temperature and ion concentrations of ambient water on the leaching process. A total of 6% of the initial ash-free dry mass of leaf litter was lost due to leaching during incubation (four days). Electric conductivity and A280 continued to increase and saturate during the incubation. To compare reaching rates of different nutrients, we fitted leaching dynamics with a hyperbolic saturation function [Y=AㆍX/(B+X)]. From these fittings, we found that ratios of leaching amounts to nutrient concentration in the litter were in the order of K > Na > Mg > P > Ca > N. Leaching from leaf litter of Z. latifolia was dependent on water temperature while it was not related with ion concentrations in the ambient water. Our results suggest that the leaching process of nutrients, especially phosphorus, from aquatic macrophytes provides considerable contribution to the eutrophication of the Paldang Reservoir ecosystem.

• 한국통신학회논문지
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• 제25권6A호
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• pp.833-838
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• 2000

본 논문에서는 IMT-2000 시스템에 응용될 수 있는 새로운 구조의 광대역 단일 패치 안테나를 제안하였다. 이 안테나는 사각형 금속 패치의 두 방사 모서리에 역시 사각형의 스티브가 각각 연결되어 있는 작고 간결한 구조이면서도 IMT-2000에 할당된 주파수 대역을 포함하는 광대역 특성을 나타내었다. 세그멘테이션 방법과 공동 모델을 함께 사용하여 안테나의 특성을 이론적으로 해석하였고, 실험 결과를 통해 비교.분석하였다. 제안된 구조로 제작된 안테나의 대역폭은 정재파비(VSWR) 2.0 이하를 기준으로 할 때, 230 MHz(11.9%)로 측정되었으며, 스티브가 달려 있지 않은 사각형 패치 안테나(4.5%)에 비해 대역폭이 2.65배만큼 넓어졌음을 확인하였다.

• 대한전기학회논문지:전력기술부문A
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• 제51권11호
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• pp.568-576
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• 2002

This paper presents a new algorithm for the enhancement of voltage stability by optimal routing (OR) technique. A new voltage stability index (VSI) for optimal routing is also proposed by using theories of critical transmission path based on voltage phasor approach and equivalent impedance method. Furthermore, the proposed algorithm automatically detect the critical transmission path to critical transmission path to critical load which are faced to voltage collapse due to additional real or reactive loading. We also adopt a improved branch exchange (IBE) algorithm based on a tie branch power (TBP) flow equation to apply the OR technique. The proposed IBE algorithm for the VSI maximizing can effectively search the optimal topological structures of distribution feeders by changing the open/closed states of the sectionalizing and tie switches. The proposed algorithm has been evaluated with the practical IEEE 32, 69 bus test systems and KEPCO 148 bus test system to show favorable performance.

• 한국전자파학회논문지
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• 제19권12호
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• pp.1410-1415
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• 2008

본 논문에서는 단일면 야기 다이폴 급전 소자와 리액턴스가 장하된 인접한 두 기생 다이폴 소자를 이용한 UNII 대역에서 동작하는 소형 빔 조향 평면형 다이폴 배열 안테나를 제안한다. 제작된 안테나는 기생 소자의 리액턴스를 전자적으로 변화시킴으로써 UNII 대역에서($5.725{\sim}5.825\;GHz$) 다이폴 수직면 $-100^{\circ}$에서 $100^{\circ}$ 범위에서 $3.3{\sim}4.3\;dB$ 이득 특성을 갖고, -10 dB 이하 반사 손실 대역폭은 $5.4{\sim}5.9\;GHz$로 UNII대역을 포함함을 측정을 통해 확인하였다.

• 한국초전도ㆍ저온공학회논문지
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• 제16권4호
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• pp.49-52
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• 2014

REBCO coated conductor (CC) tapes with superior mechanical and electromechanical properties are preferable in applications such as superconducting coils and magnets. The CC tapes should withstand factors that can affect their performance during fabrication and operation of its applications. In coil applications, CC tapes experience different mechanical constraints such as tensile or compressive stresses. Recently, the critical current ($I_c$) degradation of CC tapes used in coil applications due to delamination were already reported. Thermal cycling, coefficient of thermal expansion mismatch among constituent layers, screening current, etc. can induce excessive transverse tensile stresses that might lead to the degradation of $I_c$ in the CC tapes. Also, CC tapes might be subjected to very high magnetic fields that induce strong Lorentz force which possibly affects its performance in coil applications. Hence, investigation on the delamination mechanism of the CC tapes is very important in coiling, cooling, operation and design of prospect applications. In this study, the electromechanical properties of REBCO CC tapes fabricated by reactive co-evaporation by deposition and reaction (RCE-DR) under transversely applied loading were investigated. Delamination strength of the CC tape was determined using the anvil test. The $I_c$ degraded earlier under transverse tensile stress as compared to that under compressive one.

• 한국세라믹학회지
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• 제51권4호
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• pp.307-311
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• 2014

ZnS and $ZnS/TiO_2$ were prepared by chemical deposition. The prepared photocatalysts were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and transmission electron microscopy (TEM). The generation of reactive oxygen species was detected by monitoring the oxidation reaction from 1,5-diphenyl carbazide (DPCI) to 1,5-diphenyl carbazone (DPCO). Excellent catalytic degradation of methylene blue (MB) solution was observed using the $ZnS/TiO_2$ composites during irradiation with visible light. The results show that the photocatalytic performance of $TiO_2$ nanoparticles is improved by loading with ZnS.

• Journal of Electrical Engineering and Technology
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• 제9권4호
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• pp.1240-1247
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• 2014

The applications of Distributed Generation (DG) in a smart distribution grid environment are widely employed especially for power balancing and supporting demand responses. Using these applications can have both positive and negative impacts on the distribution system. The sizing and location of their installations are the issues that should be taken into consideration to gain the maximum benefit from them when considering the economic aspects. This paper presents an application of the Bat Algorithm (BA) for the optimal sizing and siting of DG in a smart distribution power system in order to maximize the Benefit to Cost Ratio (BCR), subjected to system constraints including real and reactive power generation, line and transformer loading, voltage profile, energy losses, fault level as well as DG operating limits. To demonstrate the effectiveness of the proposed methodology and the impact of considering economic issues on DG placement, a simplify 9-bus radial distribution system of the Provincial Electricity Authority of Thailand (PEA) is selected for the computer simulation to explore the benefit of the optimal DG placement and the performance of the proposed approach.

• Journal of Electrical Engineering and Technology
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• 제13권5호
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• pp.1769-1777
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• 2018

This paper proposes a method for optimal placement of Phasor Measurement Units (PMUs) considering system configuration and its attributes during the planning phase of PMU deployment. Each bus of the system is assessed on four diverse attributes; namely, redundancy of measurements, rotor angle and frequency monitoring of generator buses, reactive power deficiency, and maximum loading limit under transmission line outage contingency, and a consolidated 'degree of criticality' is determined using Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). The major contribution of the proposed work is the development of modified objective function which incorporates values of the degree of criticality of buses. The problem is formulated as maximization of the aggregate degree of criticality of the system. The resultant PMU configuration extends complete observability of the system and majority of the PMUs are located on critical buses. As budgetary restrictions on utilities may not allow installation PMUs even at optimal locations in a single phase, multi-horizon deployment of PMUs is also addressed. The proposed approach is tested on IEEE 14-bus, IEEE 30-bus, New England (NE) 39-bus, IEEE 57-bus and IEEE 118-bus systems and compared with some existing methods.