This article re-reads the messages of the text, 'Incendies', the uncanny actions and the strange words of protagonist Nawal, through the ideas of Jacques Lacan, particularly his notion of sexuation with posing questions about most of the previous reviews which are based on femininity or motherhood. For Lacan, masculinity and femininity are not biological essences but symbolic positions, and the assumption of one of these two positions is fundamental to the construction of subjectivity. So 'man' and 'woman' are merely signifiers that stand for these two subjective positions. Each side is defined by both an affirmation and a negation of the phallic function, by both an inclusion and exclusion of absolute non-phallic jouissance. Unlike the man, the woman is 'not-all' identified with the phallic function, demonstrating the undecidability and impossibility of totalising the woman. Although the woman is bound to do castration through being subject to the phallic function, she is also related to the signifier of the barred Other, S(Ⱥ) which stands for a gap or lack in the Other. Thus, as a consequence of not being entirely within the symbolic, she has an Other Jouissance, Feminine Jouissance, because it's possible to face emptiness of the Symbolic, the Real only in the place of the woman for new Ethics/Politics. This paper finds that Nawal is not completely defined by the phallic function and she is a subject of death drive that practices the signifying cut with passing through the fantasy as a screen for the desire of the Other. Nawal is situated on the position of the woman as 'not-all' unlike masculinity in Lacanian sexuation. This article shows that her strange acts are love, that is the true ethical acts. Above all her acts are related to the ethics of pure desire beyond the ethics of the Good of Aristotle. In that sense the character of Nawal of 'Incendies' is similar to the one of 'Antigone' as a character in all aspects. In psychoanalysis they all are true subjects that face a void, emptiness in a symbolic structure. They assume underlying impossibility of being/the Symbolic. They don't represent the images of compromise and peace in the normally accepted meaning of the word. A love that they show is not compassion but blind recognition of the excluded, embracing uniqueness of the excluded. This thesis finds resultingly Nawal's acts which can't be understood from viewpoint of feminism practice the ethics of the real, the politics of the real.
The Cheomsungdae was built in the Silla dynasty during the reign of queen Seondeok. It has a round cylindrical structure with a flowing curved fa ade. The identity of the Cheomsungdae has not been revealed since there is not much historical evidence or documents about the building. This study is trying to investigate the building technique and method from the technical point of view of the past when it was constructed. There have been much work and studies done for the Cheomsungdae, but not much were focusing on the technical aspects of the building. In addition there are many questions and doubts about the hypothesis of the building technique of Cheomsungdae since there aren't any remaining documents or historical evidence supporting it. Among many questions, we think that the discussion on falsework technique is not considering traditional construction method of the Dujabee (a traditional construction technique using various tools and equipment for the stability of the building) technique. Therefore, it is hard to identify them as reliable historical facts. As the result of the study, we want to provide the basic data on the construction techniques of Korean traditional architecture and broaden the study scope of technical history by narrowing the errors. The study could be summarized into three points. 1. The historical architecture Cheomseongdae was constructed by using traditional crane techniques such as a Noklo (pulley ladder). Cheomseongdae was re-evaluated as a high level technology for the history of architecture. 2. The benchmark method on Cheomseongdae construction has been applied with a precise scientific method based on the geometrical principals using the central axis. 3. In terms of the history of Korean traditional architecture technology, as there aren't many studies done we proposed various basic data for the traditional crane techniques and criteria of Korean traditional architecture technology. We could expect various and active studies for the technical approach of the history of architecture.
Kumaran, K. Manikanda;Chinnadurai, M.;Manikandan, S.;Murugan, S. Palani;Elakiya, E.
KSII Transactions on Internet and Information Systems (TIIS)
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v.15
no.7
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pp.2377-2398
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2021
In the recent modernized world, utilization of natural resources (renewable & non-renewable) is increasing drastically due to the sophisticated life style of the people. The over-consumption of non-renewable resources causes pollution which leads to global warming. Consequently, government agencies have been taking several initiatives to control the over-consumption of non-renewable natural resources and encourage the production of renewable energy resources. In this regard, we introduce an IoT powered integrated framework called as green home architecture (GHA) for green score calculation based on the usage of natural resources for household purpose. Green score is a credit point (i.e.,10 pts) of a family which can be calculated once in a month based on the utilization of energy, production of renewable energy and pollution caused. The green score can be improved by reducing the consumption of energy, generation of renewable energy and preventing the pollution. The main objective of GHA is to monitor the day-to-day usage of resources and calculate the green score using the proposed green score algorithm. This algorithm gives positive credits for economic consumption of resources and production of renewable energy and also it gives negative credits for pollution caused. Here, we recommend a green score based tax calculation system which gives tax exemption based on the green score value. This direct beneficiary model will appreciate and encourage the citizens to consume fewer natural resources and prevent pollution. Rather than simply giving subsidy, this proposed system allows monitoring the subsidy scheme periodically and encourages the proper working system with tax exemption rewards. Also, our GHA will be used to monitor all the household appliances, vehicles, wind mills, electricity meter, water re-treatment plant, pollution level to read the consumption/production in appropriate units by using the suitable sensors. These values will be stored in mass storage platform like cloud for the calculation of green score and also employed for billing purpose by the government agencies. This integrated platform can replace the manual billing and directly benefits the government.
The paper has focused on the 20 Iching-hexagrams from the eleventh t'ai[ ] to the final one of the Upper Book li[離] to examine the principles of learning and education involved in Xugua zhuan[序卦傳], the Ordinal Sequence of the Hexagrams as one among Ten Wings in I Ching. Some implications involved in this part of the Book of Change provides us with numerous teachings and educational principles. I try to concisely note the three teachings of the major argument as shown in the paper. Firstly, we should take the process of learning as the circular system of thought[環 相型], not as the linear system assuming the final destination like the Final Cause in the Aristotelian teleology. In the same token, the process of learning should be regarded as 'initiation', which has been initially adopted to justify the concept of education by R. S. Peters. As a circular system, there are two kinds of initiation. The one sense is 'crossing the threshold of illiteracy' seen as 'small initiation', which apprehends the points of argument in the previous paper, namely, on hexagrams from ch'ien[乾] to t'ai[泰]. The other sense is 'getting on the inside of the worthwhile activities', seen as 'Grand Initiation', which apprehend the present points of argument. Secondly, as shown in the paper, the Book enables us to recognize the process of learning as 'Seeing What Is There'. This requires us the Principles of Mean and Perfection, which are to be taken differently from the Western ones. For this a learner should always hold the endless self-reflection and attitude to re-examine the original intention of one's own, whilst he is involved in the task of learning. Finally, we should take the Principles of Change seriously, such as extremity-reversibility[物極必反] and the sense of conformity, in order that we can establish the proper educational principles to tackle the social domains of learning as well as the personal ones.
The coastal plains of the Puna and Ka' u Districts of the island of Hawaii are a contradiction to the popular view that the island of Hawaii is a tropical rain forest or a vegetated landscape with abundant water sour This section of the island lies in the rain shadow of Mauna Loa a Kilauea Volcanoes and receives less than 30 inches of annual precipita When rain does come. it is in the form of sudden down pours. givi residents of the area little time to collect and conserve water. Due to porous nature of the rock. there is no standing surface water. In spite of these harsh climatic conditions. archeological evidence indic that an extensive agriculture complex existed not only along the coast. into the most remote parts of what is called the Ka'u Desert. Pass through these agricultural areas are historic and pre - historic t systems. These trail systems apparently played a significant suppor role for exchange between the ahupua's (classic land divisions of Haw and the geopolitical districts. The question arises as to how could vast agricultural complexes a heavy foot travel over miles of arid land exist without dependable wa sources\ulcorner While planting - pits and mounds were designed to make most efficient use of available water and conserve moisture(Carter 19 9). people involved in planting also needed potable water for surv Most publications and research papers dealing with the early population this area make only oblique reference to springs and wells which t populations depended upon. The Federal Cave Resource Protection Act(1988) has served as imprtus for the National Park Service to look closer at the lava tu caves and fault cracks within Hawaii Volcanoes National Park. P visitors to these underground areas found large volumes of standing wa in fault cracks. and abundant drip areas with the lava tubes. Re observes noted that in most cases. where the cracks and caves we located in the arid sections of the park. there has been extens modifiacation or utilization of these water sources by the early Hawaii and others. The variety of western containers used for collection indica that these water sources were used during historic times. William E described similar water sources in his narrative of his trip around island in 1823(Eills 1979), This report is directed at documenting recent observations and a stimulating further research into early Hawaiian water collection syst It also explores the implications that power and political influence of e chiefs in the arid portions of Hawaii could have been linked to the con of the water resources.
Yang Zhang;Jiulong Ma;Shan Liu;Chen Chen;Qi Li;Meng Qin;Liqun Ren
Journal of Ginseng Research
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v.47
no.1
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pp.106-116
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2023
Background: Pirarubicin (THP) is an anthracycline antibiotic used to treat various malignancies in humans. The clinical usefulness of THP is unfortunately limited by its dose-related cardiotoxicity. Ginsenoside F1 (GF1) is a metabolite formed when the ginsenosides Re and Rg1 are hydrolyzed. However, the protective effects and underlying mechanisms of GF1 on THP-induced cardiotoxicity remain unclear. Methods: We investigated the anti-apoptotic and anti-oxidative stress effects of GF1 on an in vitro model, using H9c2 cells stimulated by THP, plus trigonelline or AKT inhibitor imidazoquinoxaline (IMQ), as well as an in vivo model using THP-induced cardiotoxicity in rats. Using an enzyme-linked immunosorbent test, the levels of malondialdehyde (MDA), brain natriuretic peptide (BNP), creatine kinase (CK-MB), cardiac troponin (c-TnT), lactate dehydrogenase (LDH), superoxide dismutase (SOD) and glutathione (GSH) were determined. Nuclear factor (erythroid-derived2)-like 2 (Nrf2) and the expression of Nrf2 target genes, including heme oxygenase-1 (HO-1), glutathione-S-transferase (Gst), glutamate-cysteine ligase modifier subunit (GCLM), and expression levels of AKT/Bcl-2 signaling pathway proteins were detected using Western blot analysis. Results: THP-induced myocardial histopathological damage, electrocardiogram (ECG) abnormalities, and cardiac dysfunction were reduced in vivo by GF1. GF1 also decreased MDA, BNP, CK-MB, c-TnT, and LDH levels in the serum, while raising SOD and GSH levels. GF1 boosted Nrf2 nuclear translocation and Nrf2 target gene expression, including HO-1, Gst, and GCLM. Furthermore, GF1 regulated apoptosis by activating AKT/Bcl-2 signaling pathways. Employing Nrf2 inhibitor trigonelline and AKT inhibitor IMQ revealed that GF1 lacked antioxidant and anti-apoptotic effects. Conclusion: In conclusion, GF1 was found to alleviate THP-induced cardiotoxicity via modulating Nrf2 and AKT/Bcl-2 signaling pathways, ultimately alleviating myocardial oxidative stress and apoptosis.
Park, Y.J;S.J Song;J.T Do;B.S Yoon;Kim, A.J;K.S Chung;Lee, H.T
Proceedings of the Korean Society of Embryo Transfer Conference
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2002.11a
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pp.78-78
/
2002
The role of heat shock proteins in shielding organism from environmental stress is illustrated by the large-scale synthesis of these protein by the organism studied to date. However, recent evidence also suggests an important role for heat shock protein in fertilization and early development of mammalian embryos. Effects of elevated in vitro temperature on in vitro produced bovine embryos were analysed in order to determine its impact on the expression of heat shock protein 70 (HSP70) by control and frozen-thawed after in vitro fertilization (IVF) or nuclear transfer (NT). The objective of this study was to assess the developmental potential in vitro produced embryos with using of the various containers and examined expression and localization of heat shock protein 70 after it's frozen -thawed. For the vitrification, in vitro produced embryos at 2 cell, 8 cell and blastocysts stage after IVF and NT were exposed the ethylene glycol 5.5 M freezing solution (EG 5.5) for 30 sec, loaded on each containers such EM grid, straw and cryo-loop and then immediately plunged into liquid nitrogen. Thawed embryos were serially diluted in sucrose solution, each for 1 min, and cultured in CRI-aa medium. Survival rates of the vitrification production were assessed by re-expanded, hatched blastocysts. There were no differences in the survival rates of IVF using EM grid, cryo-loop. However, survival rates by straw were relatively lower than other containers. Only, nuclear transferred embryos survived by using cryo-loop. After IVF or NT, in vitro matured bovine embryos 2 cell, 8 cell and blastocysts subjected to control and thawed conditions were analysed by semiquantitive reverse transcription polymerase chain reaction methods for hsp 70 mRNA expression. Results revealed the expression of hsp 70 mRNA were higher thawed embryos than control embryos. Immunocytochemistry used to localization the hsp70 protein in embryos. Two, 8-cell embryos derived under control condition was evenly distributed in the cytoplasm but appeared as aggregates in some embryos exposed frozen-thawed. However, under control condition, blastocysts displayed aggregate signal while Hsp70 in frozen-thawed blastocysts appeared to be more uniform in distribution.
The Journal of the Convergence on Culture Technology
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v.9
no.3
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pp.715-720
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2023
The military is driving innovative changes such as AI, cloud computing, and drone operation through the Fourth Industrial Revolution. It is expected that such changes will lead to a rapid increase in the demand for information exchange requirements, reaching all lower-ranking soldiers, as networking based on IoT occurs. The flow of such information must ensure efficient information distribution through various infrastructures such as ground networks, stationary satellites, and low-earth orbit small communication satellites, and the demand for information exchange that is distributed through them must be appropriately dispersed. In this study, we redefined the DSCP, which is closely related to QoS (Quality of Service) in information dissemination, into 11 categories and performed research to map each cluster group identified by cluster analysis to the defense "information exchange requirement list" on a one-to-one basis. The purpose of the research is to ensure efficient information dissemination within a multi-layer integrated network (ground network, stationary satellite network, low-earth orbit small communication satellite network) with limited bandwidth by re-establishing QoS policies that prioritize important information exchange requirements so that they are routed in priority. In this paper, we evaluated how well the information exchange requirement lists classified by cluster analysis were assigned to DSCP through M&S, and confirmed that reclassifying DSCP can lead to more efficient information distribution in a network environment with limited bandwidth.
Seong Won Jeon;Nuri Lee;Ki Hong Lee;Minjeong Ha;Changhyun Kim;Yoo Ri Kim;Nam Sik Yoon;Hyung Wook Park
The Korean journal of internal medicine
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v.39
no.3
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pp.458-468
/
2024
Background/Aims: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populations. This study aimed to validate the SAMe-TT2R2 score in Asian patients with AF and suggest a modified SAMe-TT2R2 score for this population. Methods: We analyzed 710 Korean patients with AF who were using warfarin. The AC quality was assessed as the mean time in therapeutic range (TTR). Each component of SAMe-TT2R2 score was evaluated for the relationship with AC. Further clinical factors that predict AC were analyzed. Identified factors were re-assorted and constructed as SA2Me-TTR scoring system. Results: Of the components of the SAMe-TT2R2 score, female, age, and rhythm control were associated with AC. Heart failure and renal insufficiency were newly identified factors associated with AC. The modified SA2Me-TTR score was reconstructed with the relevant risk factors (S, female gender, 1 point; A, age < 60 yr, 2 points; Me, medical history of heart failure, 1 point; T, treatment for rhythm control, 1 point; T, history of stroke or transient ischemic attack, 1 point; R, renal insufficiency, 1 point). The modified SA2Me-TTR score demonstrated an excellent relationship with the grading of AC. The modified SA2Me-TTR score ≤ 1 identified patients with good AC (hazard ratio 2.46, 95% CI 1.75-3.47). Conclusions: The modified SA2Me-TTR score was useful for guiding oral anticoagulants selection in Asian patients with AF.
Purpose: This is to evaluate the acute complication, resection rate, and tumor down-staging after pre-operative concurrent chemoradiotherapy for stage IIIA (N2) non-small cell lung cancer. Materials and Methods Fifteen patients with non-small cell lung cancer were enrolled in this study from May 1997 to June 1998 in Samsung Medical Center. The median age of the patients was 61 (range, 45~67) years and male to female ratio was 12:3. Pathologic types were squamous cell carcinoma (11) and adenocarcinoma (4). Pre-operative clinical tumor stages were cT1 in 2 patients, cT2 in T2, and cT3 in 1 and all were N2. Ten patients were proved to be N2 with mediastinoscopic biopsy and five had clinically evident mediastinal Iymph node metastases on the chest CT scans. Pre-operative radiation therapy field included the primary tumor, the ipsilateral hilum, and the mediastinum. Total radiation dose was 45 Gy over 5 weeks with daily dose of 1.8 Gy. Pre-operative concurrent chemotherapy consisted of two cycles of intravenous cis-Platin (100 mg/m$^{2}$) on day 1 and oral Etoposide (50 mg/m$^{2}$/day) on days 1 through 14 with 4 weeks' interval. Surgery was followed after the pre-operative re-evaluation including chest CT scan in 3 weeks of the completion of the concurrent chemoradiotherapy if there was no evidence of disease progression. Results : Full dose radiation therapy was administered to all the 15 patients. Planned two cycles of chemotherapy was completed in 11 patients and one cycle was given to four. One treatment related death of acute respiratory distress syndrome occurred In 15 days of surgery. Hospital admission was required in three patients including one with radiation pneumonitis and two with neutropenic fever. Hematologic complications and other acute complications including esophagitis were tolerable. Resection rate was 92.3% (12/l3) in 13 patients excluding two patients who refused surgery. Pleural seeding was found in one patient after thoracotomy and tumor resection was not feasible. Post-operative tumor stagings were pT0 in 3 patients, pTl in 6, and pT2 in 3. Lymph node status findings were pN0 in 8 patients, pN1 in 1, and pN2 in 3. Pathologic tumor down-staging was 61.5% (8/13) including complete response in three patients ($23.7%). Tumor stage was unchanged in four patients (30.8%) and progression was in one (7.7%). Conclusions : Pre-operative concurrent chemoradiotherapy for Stage IIIA (N2) non-small cell lung cancer demonstrated satisfactory results with no increased severe acute complications. This treatment shceme deserves more patinet accrual with long-term follow-up.
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