• 약학회지
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• 제50권3호
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• pp.145-153
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• 2006

The adverse events which do not appear in the approval process tend to occur more frequently at the early stage of the use. Therefore new drugs, drugs with different active substances or routes of administration, or drugs with explicitly different efficacy added are particularly chosen for re-examination, and go through a study, which is conducted on 600 to 3,000 subjects over 4 to 6 years. Since the re-examination system was implemented in January 1995, 880 drug products have been designated as the subject of re-examination and among them 194 drugs have been completed their re-examination as of until March 2005. Post Marketing Surveillance to insure drug safety should be correlated with re-examination of new drug, re-evaluation of drug, and adverse event monitoring system. And the first labeling change should reflect all information collected for a defined period of time after the marketing authorization is granted. Furthermore centralized management through spontaneous reporting system of adverse event for whole period of time would be the most desirable type of system.

• 디지털융복합연구
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• 제10권9호
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• pp.397-407
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• 2012

본 연구에서는 대전지역 일개 건강검진센터의 디지털화된 국민건강보험 건강검진 수검 자료를 이용하여 국민건강보험 검진환자를 효율적으로 관리할 수 있는 방안을 제시하고자 하였다. 이를 위해 대전지역 일개 건강검진센터의 2002년부터 2011년까지 10년간의 국민건강보험 건강검진 수검 자료를 수집하였으며, 수집된 자료를 이용하여 국민건강보험 검진환자의 재검진 예측모형, 민간검진 예측모형, 위암검진 예측모형을 개발하였다. 예측모형 개발 결과 연령, 거주지, 단체 또는 개인 검진 여부, 이전 국민건강보험 건강검진 횟수 등이 국민건강보험 재검진, 민간검진, 위암검진에 유의한 영향을 미치는 것으로 나타났다. 개발된 예측모형을 토대로 재검진, 민간검진, 위암검진 확률 로직을 산출하여 대전지역 일개 건강검진센터의 시스템에 적용할 수 있는 방안을 마련하였다. 국민건강보험 건강검진 환자관리 시스템을 토대로 맞춤형 서비스를 제공한다면 건강검진센터 운영의 효율화에 크게 이바지 할 수 있을 것이다.

• KIEAE Journal
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• 제13권6호
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• pp.67-75
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• 2013

The present duration of 5 years in the Korea Green Building Certification(G-SEED) should be re-set taking into account with the needs for renewal of re-certification criteria. This study methods is to analyze the differences between the characteristics of the certification system of green building of domestic and foreign and to seek the improvement to derive the problem of detailed evaluation items of the examination. The purpose of this study is to identify some problems of re-certification criteria in the G-SEED System and to propose the renewal of certification system. Analysis of the rating criteria with a few re-certified examples of office buildings have been made. Some measures to improve the re-certification have been suggested as follows; (1) it is strongly suggested to establish re-certification rating systems that is not yet made, (2) the new criteria of re-certification bring into focus on whether buildings maintain the environmental performances of the initial status certified, and (3) thus the effective duration of re-certification needs to re-set flexibly in a way to confirm to the initial environmental performances and maintenance conditions certified.

• Toxicological Research
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• 제17권
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• pp.193-196
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• 2001

Issuance of certification and licensing for toxicologists authorized by the Japanese Society of Thxicology (JST) became effective on July 24, 1997. The certification system consists of examination, eligibility requirements for the applicants, authorization/license by the board of trustees of JST, and the re-certification of previously authorized qualification. In the last 2-3 years, about 30-40% of candidates for the examination have succeeded. The Committee has estimated that the level of the examination would be sufficient to determine qualified toxicologists. This updated status and a detailed explanation are to be presented at the workshop. In global terms, the JST special committee agrees that "harmonization of certification/registration procedure for qualified toxicologists means to ensure/set the minimum requirement for the global authorization of qualified toxicologists". The following items in global authorization are ad-dressed for further discussion: (1) What's the benefit\ulcorner (2) Toxicological safety assessment standards, and (3) the JST position for authorization.orization.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2002년도 학술대회지
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• pp.559-562
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• 2002

노후 고층아파트의 재고 확대로 이에 대한 대안으로 재건축과 리모델링이 제시되었다. 재건축사업은 물리적인 노후화보다 기능적, 사회적, 경제적 노후화를 이유로 실시되어 주택의 조기 멸실에 따른 사회적 비용 증대 등 여러 가지 문제점이 제시되었다. 이에 재건축에 대한 규제는 강화되고 리모델링 관련 제도가 개선될 예정이다. 리모델링 사업의 경제성 분석에 대한 기존의 연구가 강남과 잠실 등 개발이익이 큰 곳에 편중되어 있었다. 본 연구에서는 비도심지 아파트 소유자의 입장에서 재건축과 리모델링 시 경제성 검토에 대한 하나의 안을 제시해보고자 한다.

• Journal of Preventive Medicine and Public Health
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• 제40권4호
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• pp.278-284
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• 2007

Despite extensive researches and pre-market clinical trials, only limited information on the adverse drug reactions (ADRs) of a drug can be collected at the time of market approval from regulatory agency. ADRs constitute a major public health problem. Post-marketing surveillance of drugs is important to detect signals for ADR. In Korea, one of the main methods for monitoring the safety of marketed drugs is spontaneous reporting system of suspected ADRs. Re-examination and re-evaluation system are in force for monitoring safety of new market approval drugs and currently under marketing drugs, respectively. Recently, regional pharmacovigilance centers were designated from Korean Food and Drug Administration for facilitating ADR surveillance. Over recent years, with the development of information technology, there has been an increased interest in establishing data mining system for detecting signals from Health Insurance Review Agency database. The purpose of this paper is to review the current status of Korean ADR surveillance system and suggest the possible solutions for developing active pharmacovigilance system in Korea.

• 대한치과기공학회지
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• 제28권1호
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• pp.67-81
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• 2006

This research has been attempt to examine closely factors that high cost and value to overall satisfaction state for dental implant prosthesis, re-utilization intention, inducement intention of the general hospital dental service user and provide basis data necessary to establish competitive general hospital dentistry management strategy. Collected data using own recording way questionnaire from April 17, 2004 to May 15, 2004 choosing 142 people that agree on this research and question of 361 people that dental implant prosthetic treatment finished from March 1, 1999 to March 1, 2004 for this. Major analyzation consequences are as follows : First, general satisfaction, re-utilization intention, inducement intention for implant prosthesis that highly correlation variables are kindness, explanation, medical treatment level and appreciation of the aesthetic. Second, correlation is high relatively between re-utilization intention, inducement intention in the 3 variables such as general satisfaction re-utilization intention, inducement intention. Third, the result of multiple regression analysis showed that most significant effective factors are satisfaction with explanation of dental implant prosthesis between the 3 dependant variables such as general satisfaction, re-utilization intention, inducement intention. In looking into these consequence, how to improve that raise satisfaction about dental implant prosthetic treatment and to establish patient focused care service system for dental implant prosthesis, it is consider that explain enough about implant prosthesis and raise quality of medical examination and treatment level, including satisfied with fabrication of good esthetic dental implant prosthesis.

• Imaging Science in Dentistry
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• 제49권3호
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• pp.219-228
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• 2019

Purpose: The aim of this study was to determine the reasons and solutions for intraoral phosphor storage plate (PSP) image artifacts and errors, and to develop an appropriate classification of the artifacts. Materials and Methods: This study involved the retrospective examination of 5,000 intraoral images that had been obtained using a phosphor plate system. Image artifacts were examined on the radiographs and classified according to possible causative factors. Results: Artifacts were observed in 1,822 of the 5,000 images. After examination of the images, the errors were divided into 6 groups based on their causes, as follows: images with operator errors, superposition of undesirable structures, ambient light errors, plate artifacts (physical deformations and contamination), scanner artifacts, and software artifacts. The groups were then re-examined and divided into 45 subheadings. Conclusion: Identification of image artifacts can help to improve the quality of the radiographic image and control the radiation dose. Knowledge of the basic physics and technology of PSP systems could aid to reduce the need for repeated radiography.

• Toxicological Research
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• 제16권1호
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• pp.53-57
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• 2000

A mutagenicity testing system using a specific locus mutation of Bombyx mori was introduced from National Institute of Genetics in Japan. In the system, mutagenicity could be detected by the egg color manifested by the pe and/or re genes, which is a kind of recessive visible mutation of the insect. The efficiency to detect mutagenicity of the system was examined and improved. To promote the sensitivity of the system to mutagens, eight varieties of Bombyx mori were tested for their sensitivity to two mutagens, EMS and MMC. Two varieties of the silkworm, N12 and C5, were finally selected as the most sensitive ones. The most sensitive development stage of the silkworm to mutagens was mid and late pupal stages for female and male, respectively. The system will be applied to test unknown mutagens after some more detail examination about its sensitivity.

• 한국통신학회논문지
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• 제17권1호
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• pp.47-57
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• 1992

전동기 회전시 발생되는 소음이 전동기 구조상의 소손부분 및 정도에 따라 서로 다른 소음의 특징을 갖는다는 점을 고려하여 신경회로망을 이용한 시그널(소음)인식 시스템으로써 전동기의 고장부분 탐지에 적용하였다. 적용된 신경회로망은 역전파(back-propagation)알고리즘을 써서 학습하였고 2개의 은역층을 갖는 4단 신경회로망으로 구성 되었다. 실혐 결과 전동기의 구조와 출력이 거의 일치하는 경우에는 고정 부분에 대한 항상 바른 판정을 내릴 수 있었으나 출력은 유사하더라도 전동기의 구조가 상이한 경우나 전동기 제작회사가 다른 경우에는 부정확한 판정으로 나타난다.