• Title/Summary/Keyword: Rbm

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New bone formation using fibrin rich block with concentrated growth factors in maxillary sinus augmentation (성장 인자가 농축된 Fibrin rich block을 이용한 상악동 거상술에서의 신생골 형성에 관한 연구)

  • Kim, Ji-Min;Lee, Ju-Hyoung;Park, In-Sook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.4
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    • pp.278-286
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    • 2011
  • Introduction: This study examined the predictability of new bone formation in the pneumatized maxillary sinus using only fibrin-rich blocks with concentrated growth factors as an alternative to bone grafts. Materials and Methods: Maxillary sinus augmentation was performed in thirty-three patients with a deficient alveolar bone height (mean 3.9 mm). All patients were treated consecutively with sinus membrane elevation via the lateral window approach and panoramic radiograms and cone-beam computed tomograms were taken to evaluate the remaining bone height and the new bone formation in the maxillary sinus, before and after surgery. Four biopsy specimens were taken at the time of implant consolidation (after an average of five months healing) and were stained by H & E and Trichrome staining. Results: None of the patients had postoperative complications during implant consolidation. After an average of 5 months since sinus augmentation, newly formed bone was observed in all cases by a radiographic evaluation. In 4 biopsy samples, newly formed bone was observed along the floor of the replaced bony window. The osteoblast lining and well distinguished Osteocytes in the lacunas were observed in the newly formed bone. Of the 74 implants (4 different surfaced implants - resorbable blast media-surfaced (RBM), Hydroxyapatite (HA) coated, acid-etched, sintered porous-surfaced implant) placed, one RBM implant failed. The success rate was 98.6% after a mean of 15 months. Discussion: These results suggest that maxillary sinus augmentation using fibrin rich block with concentrated growth factors is a successful and predictable technique.

SCANNING ELECTRON MICROSCOPIC STUDY OF IMPLANT SURFACE AFTER Er,Cr:YSGG LASER IRRADIATION (Er,Cr:YSGG 레이저를 조사한 임플란트 표면의 주사전자현미경적 연구)

  • Jo, Pil-Kwy;Min, Seung-Ki;Kwon, Kyung-Hwan;Kim, Young-Jo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.5
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    • pp.454-469
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    • 2006
  • Today, there is considerable evidence to support a cause-effect relationship between microbial colonization and the pathogenesis of implant failures. The presence of bacteria on implant surfaces may result in an inflammation of the peri-implant mucosa, and, if left untreated, it may lead to a progressive destruction of alveolar bone supporting the implant, which has been named as peri-impantitis. Several maintenance regimens and treatment strategies for failing implants have been suggested. Recently, in addition to these conventional tools, the use of different laser systems has also been proposed for treatment of peri-implant infections. As lasers can perform excellent tissue ablation with high bactericidal and detoxification effects, they are expected to be one of the most promising new technical modalities for treatment of failing implants. It is introduced that Er,Cr:YSGG laser, operating at 2780nm, ablates tissue by a hydrokinetic process that prevents temperature rise. We studied the change of the titanium implant surface under scanning electron microscopy after using Er,Cr:YSGG laser at various energies, irradiation time. In this study, Er,Cr:YSGG laser irradiation of implant fixture showed different effects according to implant surface. Er,Cr:YSGG laser in TPS surface with RBM not alter the implant surface under power setting of 4 Watt(W) and irradiation time of 30sec. But in TPS surface with $Ca_3P$ coating alter above power setting of 2W and irradiation time of 10sec. TPS surface with RBM showed microfracture in 4W, 30sec and TPS surface with $Ca_3P$ coating showed destruction of fine crystalline structure, melting in excess of 2W, 10sec. We concluded that proper power setting, air, water of each implant surface must be investigated and implant surface must be irradiated under the damaged extent.

ER: YAG LASER IRRADIATED IMPLANT SURFACE OBSERVATION WITH SCANNING ELECTRON MICROSCOPY (Er: YAG 레이저 조사 임프란트 표면에 대한 전자주사현미경관찰)

  • Choi, Jung-Goo;Choi, Su-Jin;Min, Seung-Ki;Oh, Seung-Hwan;Kwon, Kyung-Hwan;Choi, Moon-Ki;Lee, June;Oh, Se-Ri
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.6
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    • pp.540-545
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    • 2008
  • Since mid 20th century, dental treatments with laser have been introduced and improved a lot. Because early $CO_2$, Nd:YAG, diode, argon, and holmium lasers are used for dealing soft tissue, so it applied just limited field. But, in 1997 the lasers of erbium family that able to dealing soft and hard tissue also were introduced, laser application fields are enlarged. In today, the application fields reach on implantation treatment, so clinicians can use the laser to make holes for implantation, and flap elevation, even though treating peri-implantitis. So our class want to discover the optimal setting of Er:YAG laser when treating peri-implantitis. We observed the surface that initially treated by RBM and TPS passion and laser with varied options of exposure time and power with SEM image. For this we conclude the optimal setting range that does not alter the implant surface structure and report it.

Comparion of stability in titanium implants with different surface topographies in dogs

  • Kim, Nam-Sook;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Park, Ha-Ok;Lim, Hyun-Pil
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.47-55
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    • 2009
  • STATEMENT OF PROBLEM. A few of studies which compared and continuously measured the stability of various surface treated implants in the same individual had been performed. PURPOSE. We aim to find the clinical significance of surface treatments by observing the differences in the stabilization stages of implant stability. MATERIAL AND METHODS. Eight different surface topographies of dental implants were especially designed for the present study. Machined surface implants were used as a control group. 4 nano-treated surface implants(20 nm $TiO_2$ coating surface, heat-treated 80 nm $TiO_2$ coating surface, CaP coating surface, heat treated CaP coating surface) and 3 micro-treated surface implants [resorbable blast media(RBM) surface, sandblast and acid-etched(SAE) surface, anodized RBM surface] were used as experiment groups. All 24 implants were placed in 3 adult dogs. $Periotest^{(R)}$ & ISQ values measured for 8 weeks and all animals were sacrificed at 8 weeks after surgery. Then the histological analyses were done. RESULTS. In PTV, all implants were stabilized except 1 failed implants. In ISQ values, The lowest stability was observed at different times for each individual. The ISQ values were showed increased tendency after 5 weeks in every groups. After 4 to 5 weeks, the values were stabilized. There was no statistical correlation between the ISQ values and PTV. In the histological findings, the bone formation was observed to be adequate in general and no differences among the 8 surface treated implants. CONCLUSIONS. In this study, the difference in the stability of the implants was determined not by the differences in the surface treatment but by the individual specificity.

SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene

  • Hyunjhung Jhun;Ho-Young Park;Yasmin Hisham;Chang-Seon Song;Soohyun Kim
    • IMMUNE NETWORK
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    • v.21 no.5
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    • pp.32.1-32.14
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    • 2021
  • Over two hundred twenty-eight million cases of coronavirus disease 2019 (COVID-19) in the world have been reported until the 21st of September 2021 after the first rise in December 2019. The virus caused the disease called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Over 4 million deaths blame COVID-19 during the last one year and 8 months in the world. Currently, four SARS-CoV-2 variants of concern are mainly focused by pandemic studies with limited experiments to translate the infectivity and pathogenicity of each variant. The SARS-CoV-2 α, β, γ, and δ variant of concern was originated from United Kingdom, South Africa, Brazil/Japan, and India, respectively. The classification of SARS-CoV-2 variant is based on the mutation in spike (S) gene on the envelop of SARS-CoV-2. This review describes four SARS-CoV-2 α, β, γ, and δ variants of concern including SARS-CoV-2 ε, ζ, η, ι, κ, and B.1.617.3 variants of interest and alert. Recently, SARS-CoV-2 δ variant prevails over different countries that have 3 unique mutation sites: E156del/R158G in the N-terminal domain and T478K in a crucial receptor binding domain. A particular mutation in the functional domain of the S gene is probably associated with the infectivity and pathogenesis of the SARS-CoV-2 variant.

A retrospective study of the long-term survival of RESTORE® dental implants with resorbable blast media surface

  • Keun-Soo Ryoo;Pil-Jong Kim;Sungtae Kim;Young-Dan Cho;Young Ku
    • Journal of Periodontal and Implant Science
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    • v.53 no.6
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    • pp.444-452
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    • 2023
  • Purpose: The aim of this study was to retrospectively evaluate the survival and failure rates of RESTORE® implants over a follow-up period of 10-15 years at a university dental hospital and to investigate the factors affecting the survival rate of these dental implants. Methods: A total of 247 RESTORE® dental implants with a resorbable blast media (RBM) surface inserted in 86 patients between March 2006 and April 2011 at the Department of Periodontology of Seoul National University Dental Hospital were included. Patients with follow-up periods of less than 10 years were excluded, and data analysis was conducted based on dental records and radiographs. Results: Over a 10- to 15-year period, the cumulative survival rate of the implants was 92.5%. Seventeen implants (6.88%) were explanted due to implant fracture (n=10, 4.05%), peri-implantitis (n=6, 2.43%), and screw fracture (n=1, 0.4%). The results of univariate regression analysis using a Cox proportional hazards model demonstrated that implants placed in male patients (hazard ratio [HR], 4.542; 95% confidence interval [CI], 1.305-15.807; P=0.017) and implants that supported removable prostheses (HR, 15.498; 95% CI, 3.105-77.357; P=0.001) showed statistically significant associations with implant failure. Conclusions: Within the limitations of this retrospective study, the RESTORE® dental implant with an RBM surface has a favorable survival rate with stable clinical outcomes.

Success rate and marginal bone loss of Osstem USII plus implants; Short term clinical study (Osstem USII plus 임플란트의 단기간 성공률 및 변연골 흡수량 평가)

  • Kim, Sun-Keun;Kim, Jee-Hwan;Lee, Keun-Woo;Cho, Kyoo-Sung;Han, Dong-Hoo
    • The Journal of Korean Academy of Prosthodontics
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    • v.49 no.3
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    • pp.206-213
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    • 2011
  • Purpose: The aim of this study was to evaluate the clinical value of Osstem$^{(R)}$ USII plus system implants. Clinical and radiographic data were analyzed for 88 implants placed and functionally loaded for a 12 month period at the Yonsei University Dental Hospital. Materials and Method: Based on the patient's medical records, clinical factors and their effects on implant marginal bone resorption, distribution and survival rate were analyzed. The marginal bone loss was evaluated at implant placement and during a 6 to 12 months functional loading period. The independent sample t-test was used to evaluate the interrelationship between the factors (${\alpha}$=0.05), and one way repeated measures ANOVA was used to compare the amount of marginal bone resorption. Results: The cumulative survival rate for 88 implants was 100%. The marginal bone resorption from implant placement to prosthetic delivery was 0.24 mm and the average marginal bone resorption from prosthetic delivery to 12 months of functional loading was 0.19 mm. The total average bone resorption from implant placement to 12 months of functional loading was 0.43 mm. There were no statistically differences in the amount of marginal bone resorption when implants were placed in the maxilla or the mandible (P>.05), however, implants placed in the posterior areas showed significantly more marginal bone loss than those placed in the anterior areas (P<.05). Conclusion: Based on these results, the short term clinical success rate of RBM surface treated external connection domestic implants showed satisfactory results and the marginal bone loss was in accord with the success criteria of dental implants.

Comparison of the SNR in the MR images on dental implant material (치아 임플란트 재료에 따른 자기공명영상의 SNR 비교)

  • Kim, Dong-Hyun;Ko, Seong-Jin;Ye, Soo-Young
    • Journal of the Institute of Convergence Signal Processing
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    • v.16 no.4
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    • pp.149-155
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    • 2015
  • Tooth implant is located in oral cavity and affects neck, skull base, and facail image. These magnetic inhomogeneities are usually frequency encoding direction which cause artifacts due to change of signal strength and geometric distortion. First, to evaluate signal to noise ratio (SNR) of magnetic resonance image caused by tooth implant this study uses meat phantom which is similar to human body and is consisted with fat, muscle, and water to measure signal to noise ratio. Second, signal to noise ratio by using custom-made fixed phantom is measured, and then signal to noise ratio size of different tooth implant types is compared and analyzed. The measured signal to noise ratio values of Brushite, HSA, Metal, and RBM for meat phantom were 2.76, 2.22, 1.88, and 1.57 on T1 SE, 1.88, 1.78, 1.65, and 1.79 on T2 FLAIR, 2.28, 2.25, 2.88, and 2.05 on T2 FSE, and 2.74, 1.94, 1.67, and 1.48 on T2 GRE. The measured signal to noise ratio values of Brushite, HSA, Metal, and RBM for fixed water phantom were 1.2, 1.06, 1.12, and 1.22 on DWI, 1.93, 1.87, 1.93, and 2.06 T1 SE, 1.83, 1.76, 1.82, and 1.92 on T2 FLAIR, 1.85, 1.79, 7.86, and 1.97 on T2 FSE, and 1.97, 1.93, 1.99, and 2.06 on T2 GRE. By considering through the results, patients and dentists need to consider some impacts from testing many aspects although their main purpose of having tooth implants is a dental restoration. Moreover, depending on the tooth implant characteristics of individual patients this study results can be used as baseline data when choosing test protocol.

CFD Analysis of Performance of KRISO Devices (K-DUCT) for Propulsion Efficiency Improvement (CFD를 이용한 KRISO 추진효율 향상 장치(K-duct)의 성능 해석)

  • Suh, Sung-Bu
    • Journal of Ocean Engineering and Technology
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    • v.31 no.3
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    • pp.183-188
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    • 2017
  • This paper provides numerical results for the estimation of the efficiency of KRISO energy saving devices in the design stage. A finite volume method is used to solve Reynolds averaged Navier-Stokes (RANS) equations, where the SST k-$\omega$ model is selected for turbulence closure. The propeller rotating motion is determined using a rigid body motion (RBM) scheme, which is called a sliding mesh technique. The numerical analysis focuses on predicting the power reduction by the designed KRISO devices (K-DUCT) under a self-propulsion condition. The present numerical results show good agreement with the available experimental data. Finally, it is concluded that CFD can be a useful method, along with model tests, for assessing the performance of energy saving devices for propulsion efficiency improvement.

A Study on the Safety Enhancement of Chemical Plants Using Risk Based Inspection Method (Risk Based Inspection 기법을 이용한 화학공장의 안전성 향상에 관한 연구)

  • 노용해;유진환;서재민;임차순;고재욱
    • Journal of the Korean Society of Safety
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    • v.17 no.3
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    • pp.73-80
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    • 2002
  • The RBI technique proposed by API is composed of three steps. The qualitative RBI method can be used for the purpose of screening the components with high risk. And the quantitative RBI method employs complex risk evaluation model for predicting component risk in a quantitative manner. The inspection program can be optimized based on the results obtained by these RBI technique. The forementioned RBI technique has been applied to a common hydrodesulfurizer unit and the technique is critically evaluated for studying its benefits and limitations, which is the main issue of this thesis. It's conducted that the RBI method can provide a method for defining and measuring the component risk, and also provide a powerful tool for managing many of the important elements of a process plant.