• Archives of Reconstructive Microsurgery
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• 제6권1호
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• pp.111-116
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• 1997

The treatment of chronic digital pain and cold intolerance due to Raynaud's phenomenon is quite difficult especially it is combined with scleroderma. Several surgical trial such as cervicothoracic sympathectomy have been attempted for the medically unresponsible Raynaud's phenomenon, but their results were unsatisfactory. We have tried peripheral periarterial sympathectomy for the 44 years old female patient who had medically unresponsible severe Raynaud's phenomenon with scleroderma. Periarterial adventitial stripping was performed at the level of wrist, superficial palmar arch, common digital artery and proper digital artery about 1.5-2 cm in length. Preoperative angiography and radioactive angiography were done and preoperatively and postoperatively the blood flow was measured by the desk top computer-aided histogram. Both hands digital pain were markedly reduced after operation and blood flow increased as compaired with the preoperative measure.

• 대한약침학회지
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• 제12권1호
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• pp.103-108
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• 2009

Objectives : This study is to report the effect of Pharmacopuncture therapy on a patient suffering from the pain and cold intolerance of hand caused by Carpal tunnel syndrome with Raynaud's phenomenon. Methods : We had treated the patient diagnosed as Carpal tunnel syndrome with Raynaud's phenomenon by Sweet BV and CF pharmacopuncture. We injected Sweet BV and CF into acupuncture points on both hands - Sweet BV into Baxie (EX-UE9), CF into Naegwan ($PC_6$) and Daereung ($PC_7$). And then we evaluated her symptoms by VAS (Visual Analog Scale). Results : Clinical symptoms about Carpal tunnel syndrome with Raynaud's phenomenon were remarkably improved by Sweet BV and CF Pharmacopuncture. Conclusion : Therefore, we concluded that pharmacopuncture therapy - Sweet BV, CF etc. - may be useful to treat Carpal tunnel syndrome with Raynaud's phenomenon.

• 대한한방내과학회지
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• 제39권4호
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• pp.846-852
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• 2018

Objective: The aim of this report is to report the effects of Danggwisaeyeok-tang (當歸四逆湯) on Raynaud phenomenon in a patient. Methods: A 57-year-old male diagnosed in 2016 with Raynaud's phenomenon complained of pain, digital ulceration, and discoloration of his fingers. He underwent acupuncture and electroacupuncture treatment, but the symptoms gradually worsened, so we administered herbal medicine, Danggwisaeyeok-tang (當歸四逆湯). Visual observation of the affected part, changes in subjective symptoms, and a verbal numerical rating scale (VNAS) were used to assess the clinical response. Results: After treatment with Danggwisaeyeok-tang, the patient reported improvement in his symptoms of cold sensation, ulceration, and sclerosis of his digits. Furthermore, the patient exhibited no general adverse effects. Conclusions: Danggwisaeyeok-tang (當歸四逆湯) significantly improved the patient's clinical symptoms. This case suggests that Danggwisaeyeok-tang (當歸四逆湯) may represent a good option for the treatment of Raynaud's phenomenon.

• 한방안이비인후피부과학회지
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• 제31권4호
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• pp.108-116
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• 2018

Objectives : A Report on the Improvement of korean medical treatment of Secondary Raynaud's Syndrome Caused by Systemic Sclerosis. Methods : We treated a Secondary Raynaud's syndrome 59-year-old woman with herbal medicine and acupuncture treatment for 3 months. The evaluation of treatment was confirmed by photographs before and after treatment, VAS, and palm skin temperature. Results : After treatment, the color of both fingernails and finger skins recovered from white to purplish red, and Raynaud phenomenon and palm flaring were decreased. VAS decreased from 8 to 2 and palm skin temperature increased by left hand 1.4 degrees right hand 1.2 degrees. Conclusions : It was shown that korean medical treatment was effective in the conservative treatment of Secondary Raynaud's syndrome caused by systemic sclerosis.

• Journal of Chest Surgery
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• 제6권2호
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• pp.213-218
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• 1973

Raynaud attempted to clarify the situation concerning symmetrical and spontaneous gangrene in a thesis published in 1952. The disease was defined as Raynaud`s phenomenon without associated and contributing conditions or disease, and described as two types, such as, `locale syncope and asphyxia` and `gangrene`. Predilection of Raynaud`s disease for female under 40 years of age wi-thout any vascular occlusive disease beginning in the early decades of life and typical color changes in the skin of the extremities incited by coldness are outstanding features in this disease. One typical case of Raynaud`s disease is presented with relating references. Patient was 24 year old female single patient, who noted pain, numbness, and cyanosis of the finger tips of both hands for 6 years previously in the winter season, and recently such symptoms were aggravated including her both feet for two years even in the summer after exposure to cold water. Physical and laboratory examination revealed nothing specific except slightly glistening tight face and hypertrophy of both finger tips with clammy coldness. FamiliaI and past history revealed nothing specific abnormal contributory factors. Biopsy of skin on the dorsum of right foot one year before this admission revealed no evidence of scleroderma. Treatment was aimed to relieve vasospasmodic reaction to coldness and was very successful with bilateral lumbar and thoracic sympathectomy. Patient is free of symptoms relating to the Raynaud’s phenomenon after sympathectomy for 6 months including winter season.

• 한국방사선학회논문지
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• 제13권2호
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• pp.283-290
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• 2019

본 연구의 목적은 레이노 현상 의심 환자의 정량적 판독 보조 지표의 가능성을 확인하고자 하는 것이다. 레이노 현상 의심 환자 99명에서 가능성 낮음 48명, 중간 16명, 높음 35명을 대상으로 하였다. 검사는 $15.2{\pm}0.8^{\circ}C$ 얼음물에 10분 간 양 손을 한랭 부하 후 $^{99m}Tc$ 370 MBq(10 mCi)를 정맥 주사하였다. 이 후 5분, 10분, 20분 양측 열 손가락의 온도 변화를 측정하였고, 핵의학 판독의의 판독 결과와 온도 변화를 비교하였다. 판독 결과 레이노 현상의 가능성이 낮은 군은 손가락 온도가 $32.6{\pm}4.9^{\circ}C$로 높게 측정되었고, 가능성이 높은 군은 $22.7{\pm}6.0^{\circ}C$로 낮게 측정되었다(p<0.05). 결론적으로 레이노 현상 의심 증상에 따라 손가락 온도의 차이가 났음을 확인하였고 이를 통해 손가락 온도의 측정이 레이노 진단의 정량적 보조 지표로서의 가능성이 있음을 확인하였다.

• Clinical and Experimental Pediatrics
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• 제51권8호
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• pp.886-891
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• 2008

복합 교원성 질환은 류마티스 관절염, 경피증, 전신성 홍반성 낭창, 다발성 근염의 다양한 임상양상을 나타내면서 혈청학적 검사에서 항 ENA 항체를 갖는 질환이다. 성인에서 1972년 25례의 복합 교원성 질환의 첫 보고 이래 국내에서 성인에서 발생한 복합 교원성 질환에 대한 몇몇 보고가 있었지만, 소아에서는 복합 교원성 질환의 보고가 드물다. 7세 여아가 내원 3개월 전부터 시작된 양 손가락에, 글쓰기 및 한랭노출에 의해 유발되는, 가역적인 색깔변화와 차가움을 주소로 내원하였다. 신체 검사에서 양측 손가락들의 부종 및 오른쪽 집게손가락 끝에 궤양이 관찰되었다. 혈청학적 검사에서 다른 교원성 질환의 증거 없이 높은 역가의 ANA와 항 ENA 항체 중 항 RNP 항체가 고역가로 검출되었다. Raynaud 현상과 궤양에 대해 slow releasing nifedipin을 사용하였으나 호전 보이지 않아 스테로이드를 투약 하였고, 이후 궤양은 치유 되었으며, Raynaud 현상의 빈도도 현저히 감소하였다. 그러나 steroid를 점차 감량하는 동안 탈모 및 관절염 증상이 새로 발현되었으며, 현재 겨울에 악화되는 Raynaud 증상과 관절염으로 추적 관찰 중이다. 이에 본 저자들은 Raynaud 현상으로 발현되고 추적 동안에 탈모와 관절염이 나타난 복합 교원성 질환의 드문 소아 증례를 보고하는 바이다.

• 대한미세수술학회:학술대회논문집
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• 대한미세수술학회 1997년도 제17차 학술대회
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• pp.130.2-131
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• 1997

• 대한핵의학회지
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• 제21권2호
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• pp.183-190
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• 1987

In Raynaud's phenomenon, the authors measured finger blood flow after ice water exposure by analyzing the time activity curve of radionuclide angiography on both hands. The results were as follows: 1) The digital blood flow did not decrease after ice water exposure in normal subjects. 2) In the patients with Raynaud's phenomenon, there were two groups: the one had decreased digital blood flow after cold exposure, and the other had paradoxically increased digital blood flow after cold exposure. 3) There was no difference in the digital blood flow of hand in room temperature between the normal and the patients with reduced digital blood flow after cold exposure, but the digital blood flow of the hand in room temperature was markedly reduced in the patients with paradoxically increased flow after cold exposure. 4) In the static image the difference was not significant in comparision with the dynamic study, because it represents pooling of the blood in the vein rather than flow. 5) After the treatment with nifedipine, the digital blood flow increased. In conclusion, the radionuclide angiography was useful in measuring the digital blood flow in Raynaud's phenomenon, and further studies with various drugs is expected.

• 대한한방내과학회지
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• 제25권3호
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• pp.559-568
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• 2004

Diagnosis of Raynaud's phenomenon is primarily based on clinical symptoms. Cold stress test(CST) done by DITI(Digital Infrared Thermographic Image) can be helpful for objective diagnosis. The cold stress test was performed three times by DITI; the first after 15 minutes of rest, the second right after one minute of soaking in $20^{\circ}C$ water, the third ten minutes after immersion. For a clear diagnosis, the temperature of the finger tips must be low, or the thermal difference between the metacarpophalangeal joints and the fingertips must be large. Also the evaluation of treatment depends on decrease of thermal gradient between the metacarpophalangeal joints and the finger tips after CST. In oriental medicine Raynaud's phenomenon can be categorized by coldness of the limbs or numbness. Numbness was diagnosed as depression of Ki and Chiljehyangbuhwan(Qizhixiangfuwan) was prescribed. Positive results were observed, not only in follow up CST, but also Visual Analogue Scale after treatment.