• Journal of Korean Biological Nursing Science
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• v.17 no.4
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• pp.341-347
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• 2015

Purpose: Chrysanthemum indicum (CHI) has been used for edible and medical purposes for a long time in Korea. The purpose of this study was to evaluate the anti-inflammatory effects of CHI water extract in lipopolysaccharides (LPS)-induced RAW 264.7 macrophage cells. Methods: To investigate the anti-inflammatory effects on LPS-induced RAW 264.7 macrophage cells, CHI extract as a whole plant was used in this study. RAW 264.7 cells were treated with various concentrations of CHI extract (1, 10, and $100{\mu}g/mL$). After that Nitric Oxide (NO), inducible nitric oxide synthase (iNOS), interleukin (IL)-$1{\beta}$, cyclooxygenase (COX)-2 and prostaglandin $E_2$ ($PGE_2$) expression level were measured. Results: CHI extract significantly suppressed the LPS-induced NO production and decreased the level of iNOS, IL-$1{\beta}$, COX-2 messenger ribonucleic acid (mRNA) expression and also the down regulation of $PGE_2$ expression in a dose-dependent manner. Conclusion: The present study suggested that CHI extract can be substituted for anti-inflammatory drugs and provide a safe and effective non pharmacological therapeutic approach.

• Journal of the Korean Ceramic Society
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• v.41 no.4
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• pp.323-327
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• 2004

This study has been carried out to use the municipal solid waste sewage sludge ash generated at sewage disposal field as the raw materials of Ordinary Portland Cement (OPC). Limestone, shale, converter slag, and fly ash were used as the main raw materials. After the raw materials were mixed, these were fired at 1,300, 1,350, 1,400, 1,450, and 1,500$^{\circ}C$ for 1 h and cooled rapidly in air. The properties of clinker synthesized were examined with XRD, SEM, and burnability index by polysius method.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.2
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• pp.187-196
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• 2017

The size of raw data has dramatically increased due to the recent trend of Synthetic Aperture Radar(SAR) development plans for high resolution and high definition image acquisition. The large raw data has an impact on satellite operability due to the limitations of storage and transmission capacity. To improve the SAR operability, the SAR raw data shall be compressed before transmission to the ground station. The Block Adaptive Quantization (BAQ) algorithm is one of the data compression algorithm and has been used for a long time in the spaceborne SAR system. In this paper, an optimization method of BAQ threshold table is introduced using real SAR raw data to prevent the degradation of signal quality caused by data compression. In this manner, a new variation estimation strategy and a new threshold method for block type decision are introduced.

• Journal of Environmental Science International
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• v.21 no.9
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• pp.1031-1041
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• 2012

This study was carried out to investigate the characteristics of disinfection by-products (DBPs-trihalomethanes (THMs), haloacetic acids (HAAs) and haloacetonitriles (HANs) formation in chlorination of principal raw waters used for drinking water on Jeju Island, Korea. The domestic water supply of other area and humic acid solution (HA) were used as a reference point. The effects of chlorine contact time, solution temperature and pH on DBPs formation potential (DBPFP) were investigated for raw waters. In addition, the effect of $Br^-$ was studied for HA. The DBPFP (THMFP, HAAFP and HANFP) were increased with increasing chlorine contact time. Comparing the individual DBPFPs for raw waters, they decreased in the order of HAAFP > THMFP ${\geq}$ HANFP. As the solution temperature was increased, the THMFP, HAAFP and HANFP increased. With increasing the solution pH, the THMFP was increased, but HAAFP and HANFP were decreased. With the addition of 0.3 mg/L $Br^-$ for HA, the DBPFP was increased and the major chemical species changed: from trichloromethane to dibromochloromethane and tribromomethane for THMs; from dichloroacetic acid and trichloroacetic acid to tribromoacetic acid for HAAs; and from dichloroacetonitrile to dibromoacetonitrile for HANs.

• Journal of Institute of Control, Robotics and Systems
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• v.21 no.3
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• pp.265-275
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• 2015

This paper describes extraction methods of five different types of geometrical features (line, arc, corner, polynomial curve, NURBS curve) from the obtained raw data by using a two-dimensional laser range finder (LRF). Natural features with their covariance matrices play a key role in the realization of feature-based simultaneous localization and mapping (SLAM), which can be used to represent the environment and correct the pose of mobile robot. The covariance matrices of these geometrical features are derived in detail based on the raw sensor data and the uncertainty of LRF. Several comparison are made and discussed to highlight the advantages and drawbacks of each type of geometrical feature. Finally, the extracted features from raw sensor data obtained by using a LRF in an indoor environment are used to validate the proposed extraction methods.

• Journal of Korean Society for Quality Management
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• v.16 no.1
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• pp.78-87
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• 1988

The purpose of this study is to develop the algorithm applicable to the integrated production inventory model under quantity discount. To achieve this purpose, the integrated production inventory model which unifies the inventory problem of raw materials and the finished product for a single product manufacturing system is considered. The product is manufactured in batches and the raw materials are obtained from outside suppliers but some of the raw materials are discounted according to the purchasing quantity. The intergrated production inventory problem considered in this study is formulated by the non-linear mixed integer programming model, and the optimal solution is obtained by using the algorithm developed by Goyal. Then, the algorithm developed by this study is applied to the quantity discount problem, and the optimal solution is revised by this results. The quantity discount algorithm of the integrated production inventory model developed by this study gives a systematic procedure to obtain the optimum policy to minimize the total cost in any case. The numerical example involving 20 raw materials and 5 raw materials among them are discounted according to the purchasing quantity is given to verify the mathematical model and the algorithm developed in this study.

• Toxicological Research
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• v.13 no.3
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• pp.247-250
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• 1997

We have studied cytotoxicity of S-nitroso-N-acetyl- N-DL-penicillamine(SNAP), a Nitric oxide (NO)-releasing compound, in RAW264.7 macrophages. SNAP is cytotoxic to RAW264.7 cells in a concentration-dependent manner. PMA(200 nM) stimulated cells to produce superoxide anton radical($O_2^{-\cdot}$) and caused a little loss of RAW264.7 cell viability for 12 hr and diminished the cytotoxicity of SNAP. The mechanism by which PMA can protect cells against NO-mediated cytotoxicity was studied by peroxynitrite-enhanced chemiluminescence method. Observed results suggested that $O_2^{-\cdot}$ produced by PMAstimulated RAW264.7 cells may quench NO released by SNAP and reduce NO, thus attenuating NO-related damages.

• Journal of Forest and Environmental Science
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• v.29 no.4
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• pp.324-330
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• 2013

This study investigated the anti-inflammatory effects of Xanthoceras sorbifolia of seeds oil on RAW264.7 macrophages and TPA (12-O-tetra decanoylphorbol-acetate)-induced ear edema mice. MTT assay method to measure cytotoxicity was formed in RAW264.7 cell. The anti-inflammatory effect was measured by ability to inhibit production nitric oxide (NO) in RAW264.7 cell. Hexane and eight-percent methanol fractions from Xanthoceras sorbifolia seeds oil did not show cytotoxicity. Hexane and eight-percent methanol fractions were showed significantly inhibitory effect on NO production. TPA-induced acute edema was developed in the mouse ears, and Xanthoceras sorbifolia seeds oil dissolved in acetone was applied to inflamed ears. It was found out that Xanthoceras sorbifolia seeds oil could significantly reduce th ear swelling, compared to the control. Overall results indicate that the Xanthoceras sorbifolia seeds oil has anti-inflammatory activity and could be used as a resource of anti-inflammatory materials.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.3
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• pp.528-533
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• 1997

This study was undertaken to determine the antimutagenic effects of Synurus deltoides extracts on the mutagenesis induced by 3-amino-1, 4-dimethyl-5-H-pyrido[4, 3-blindol(Trp-P-1), 2-amitnofluorene (2-AF) and 4-nitroquinolin-1-oxide(4NQO) using Ames test. Raw juice, heated juice, and ethanol extract from Synurus deltoides itself did not induce mutagenesis. The raw juice, heated juice and ethanol extract of 50${mu}ell$/plate showed approximately 90%, 37% and 28% inhibitory effect on the mutagenesis induced by Trp-P-1 against TA98 strain, while 80%, 60% and 58% inhibition was observed on the mutagenesis induced by 2-AF at the concentration of 200${mu}ell$/plate, respectively. TA100 strain was more sensitive than TA98 strain by raw juice, heated juice and ethanol extract on the mutagenesis induced by Trp-P-1 and 2-AF. Meanwhile, the raw juice, heated juice, and ethanol extract showed very limited inhibitory effects on the mutagenesis induced by 4-NQO against TA98 and TA100 strain. These results indicate that raw juice had the strongest inhibitory effect on the Trp-P-1 or 2-AF induced mutagenesis, but all of the extracts had a little antimutagenc effects on the 4-NQO induced mutagenesis.

• Journal of Advanced Navigation Technology
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• v.21 no.5
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• pp.514-519
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• 2017

In this paper, the pseudorange-based GPS performance using the Android's raw measurements is compared with NMEA. In order to compare the performance between the two different implementations, we used Nexus 9 tablets and collected the raw measurements and NMEA data using the GNSS logger application provided by Google. To verify the performance of the final coordinates calculated, the VRS was used as the reference coordinate and compared with the NMEA results. The resulting horizontal, vertical, and 3D RMS errors of the pseudorange-based GPS using the Android's raw measurements are 3.05, 3.82, and 4.97 m, respectively, which correspond to 32% horizontal, 65% vertical and 49% 3D performance improvement compared with NMEA.