• Biotechnology and Bioprocess Engineering:BBE
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• v.1 no.1
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• pp.13-17
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• 1996

The protein disulfide isomerase(PDI) reaction kinetics has been studied to evaluate its effect on the monoclonal antibody(MAb) refolding and assembly which accompanies disulfide bond formation The MAb in vitro assembly experiments showed that the assembly rate of heavy and light chains can be greatly enhanced in the presence of PDI as compared to the rate of assembly obtained by the air-oxidation. The reassembly patterns of MAb intermediates were identical for both with and without PDI, suggesting that the PDI does not determine the MAb assembly pathway, but rather facilitates the rate of MAb assembly by promoting PDI catalyzed disulfide bond formation. The effect of growth rate on PDI activities for MAb production has also been examined by using continuous culture system. The specific MAb productivity of hybridoma cells decreased as the growth rate increased. However, PDI activities were nearly constant for a wide range of growth rates except very high growth rate, indicating that no direct correlation between PDI activity and specific MAb productivity exists.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.44 no.3
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• pp.282-287
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• 1999

The object of this study was to determine the difference of the time course changes of transpiration, diffusion resistance and photosynthetic rate of rice at several different growth stages subjected to soil moisture stress (SMS) and recovery by irrigation. A japonica rice cultivar 'Dongjinbyeo', was grown under flooded condition in a plastic container filled with silty loam soil. At 5 main growth stages, the container was treated by SMS until initial wilting point (IWP) and then reirrigated. The duration of SMS until IWP were the longest, 13 days for tillering stage, and the shortest, 7 days for panicle initiation and meiosis stage. The transpiration rate rapidly decreased during SMS and the transpiration rate at IWP of the stressed plant showed 10∼20% compared with control, and the transpiration rate of stressed plant at most growth stages also recovered rapidly after irrigation and then reached 100% of control within a week. The shoot photosynthetic rate in all growth stages rapidly decreased by SMS, and the rates at IWP of stressed plants were de-creased nearly to 0%, beside the treatment at tillering stage. The recovery degree of photosynthetic rate by irrigation ranged from 20 to 90%, showed higher at early growth stages of SMS treatment than that of later stages. At all growth stages the leaf diffusion resistance of stressed plants was over 3 times that of the control resulting from a rapid increase at 3 to 5 days after draining for SMS, and showed quick recovery by irrigation within 3 days after drainage. The above physiological parameters changed in close relation with the decrease of the soil matric potential after SMS. These results indicate that at all main growth stages of rice plants the transpiration and photosynthesis reduction by stomatal closure reponded sensitively to the first stage of SMS closely related with decrease of soil water potential, while those recovery pattern and recovered degree by irrigation are little different by growth stage of rice.

• Korean Journal of Crystallography
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• v.3 no.1
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• pp.23-30
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• 1992

a-SiC crystals were grown on the (001) plane of a-SiC seed crystals by sublimation method to find effects of pressure-reduction rate of the crystal growth furnace own the growth rate and orientstion of grown SiC crystals. Pressure-reduction rate at the initial growth stage affected the crystallinity of grown SiC crystals. In case of high pressure-reduction rate, growth rate was high and 3csic polycrystalline was grown on the seed. On the other hand, low pressure-reduction rate caused the growth rate to be slow and 6H-SiC single crystal was grown on the seed. However, even after growing SiC for 2 hours under the condition in which.

• Journal of Welding and Joining
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• v.28 no.5
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• pp.45-50
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• 2010

The fatigue crack growth characteristics of base metal and weld joint of 9% Ni steel for LNG storage tank was carried out using CT specimen at room temperature and $-162^{\circ}C$. Fatigue crack growth rate of base and weld metals at RT and $-162^{\circ}C$ was coincided with a single line independent of the change of stress ratio and temperature. In the region of lower stress intensity factor range, fatigue crack growth rate at $-162^{\circ}C$ was slower than that at RT, and the slop of fatigue crack growth rate at $-162^{\circ}C$ increased sharply with propagating of fatigue crack, fatigue crack growth rate at RT and $-162^{\circ}C$ was intersected near the region of $2{\times}10-4\;mm$/cycle, and after the intersection region, fatigue crack growth rate at $-162^{\circ}C$ was faster than that at RT. The micro-fracture mechanism using SEM shows the ductile striation in the stable crack growth region. Also the defects of weld specimen after fatigue testing were detected using the A scan of ultrasonic apparatus.

• Journal of Nutrition and Health
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• v.26 no.6
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• pp.783-792
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• 1993

This study examined the difference in growth rate between Korean breast-fed(BF) and formula-fed(FF) infants(n=31) at 1, 2 and 3 months postpartum. The results indicated that the growth rate was comparable between groups, but that of the BF infants tended to be slow during the first three months. The intakes of energy, protein and lipid except lactose of the FF infants were greater than those of the BF infants, however the difference in growth rate did not correlate to these variables. But these results suggest that the availability of nutrients might be different between the BF infants and the FF infants.

• Microbiology and Biotechnology Letters
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• v.43 no.3
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• pp.187-194
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• 2015

In this study, L. plantarum, when reacting with the culture media of potential pathogenic bacteria, exhibited an increase in growth rate and antimicrobial activity. In order to examine the characteristics and the nature of the reaction with the bacteria, this study carried out experiments involving culturing the test bacteria in M9 minimal media. Subsequently, the supernatant was incrassated by the decompression-drying method. Through colony forming unit assay, it was confirmed that L. plantarum had the function of growth inhibition to various bacteria. After culturing L. plantarum with bacterial media, the growth rate of L. plantarum was measured by absorbance (OD₆₀₀), the results showed that the growth rate (E. coli treatment group: OD₆₀₀ = 0.848, S. typhimurium treatment group: OD₆₀₀ = 0.848) increased, as compared with the non-treated control group (OD₆₀₀ = 0.48). In contrast, the concentrate itself did not induce the growth of L. plantarum. These results were observed as a universal phenomenon of the Lactobacillus species. Moreover, the increase in antimicrobial activity was observed in L. plantarum, which reacted with the culture media of E. coli and S. typhimurium, through a disc diffusion assay, and the result of growth inhibition against various bacteria was induced. Finally, based on the analysis results of the characteristics of bacteria culture media, which increased the growth rate of L. plantarum and antibacterial activity, the bacterial media had a tolerance for catabolic enzymes, pH 2−8 and heat. Therefore, this substance can be said to be a small molecule which is highly stable under various conditions.

• Environmental Analysis Health and Toxicology
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• v.17 no.3
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• pp.219-224
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• 2002

This study was carried out to examine the effects of bis (tribytyltin)oxide (TBT), endocrine disrupting compounds (EDCs). on the changes of survival, growth and oxygen consumption rate in the oliver flounder, Paralichthys olivaceus. Oliver Flounders were exposed to sublethal concentration of TBT (0, 1.67, 3.20, 6.30 and 12.50 $\mu\textrm{g}$/L) during 6 weeks. Survival rate was decreased in a concentration and exposure period-dependent way and suddenly the reduction of more than 20% occurred at TBT concentration greater than 3.20 $\mu\textrm{g}$/L. after exposure 6 weeks. Growth rate and feed efficiency significantly decreased at concentration greater than 3.20 $\mu\textrm{g}$/L. Oxygen consumption rate was also decreased in a concentration-dependent way and significantly decreased to 17,48 and 67％ than that of the control at the TBT concentration of 3.20, 6.32 and 12.50 $\mu\textrm{g}$/L, respectively. This study revealed that high TBT concentration ($\geq$3.20 $\mu\textrm{g}$/L) reduced growth and oxygen consumption rates of the juvenile oliver flounder suggesting potential influence on the natural mortality of Paralichthys olivaceus in the coastal areas.

• Journal of Applied Reliability
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• v.5 no.3
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• pp.381-391
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• 2005

The level of reliability attained largely depends upon the investment in reliability growth programs during development phase. In order to find the relationship between reliability growth test time and BRTE(basic reliability tasks effectiveness) in a reliability improvement program that minimizes LCC in which contains the reliability growth cost, repair and replacement costs, and spare parts ordering costs in service with given service rate in management policy, the growth rate has been suggested proper LCC versus growth rate. This model employs the reliability growth projection with delayed fixes in avionic equipment based on AMSAA.

• The KIPS Transactions:PartD
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• v.13D no.5 s.108
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• pp.709-716
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• 2006

As the software complexity increases, the development success rate decreases and failure rate increases exponentially. The failure rate related to the software size can be described by a growth function. Based on this phenomenon, this paper estimates the development success and completion rate using the Gompertz growth function. At first, we transformed a software size of numerically suggested $10^n$ into a logarithm and kept the data interval constantly. We tried to derive a functional relationship between the development success rate and the completion rate according to the change of logarithmic software size. However, we could not find a function which can represent this relationship. Therefore, we introduced the failure rate and the cancel rate which are inverse to the development success rate and completion rate, respectively. Then, we indicated the relation between development failure rate and cancel rate based on the change of software size, as a type of growth function. Finally, as we made the Gompertz growth function with the function which describes the cancel rate and the failure rate properly. We could express the actual data suitably. When you apply the growth function model that I suggested, you will be able to get the success rate and completion rate of particular site of software very accurately.

• Journal of the Korean Society of Safety
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• v.13 no.4
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• pp.79-86
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• 1998

The effect of specimen thickness on fatigue crack growth behavior has been carried out by compact tension specimens of thickness of 3mm, 10mm and 25mm for maraging steel and Al 7075-T6. The closure points were determined during the test by means of a clip-gage situated at the notch mouth. Specimen thickness have no apparent influence on the fatigue crack growth rate of maraging steel, but the crack growth rate of 25mm thickness specimen for Al 7075-T6 is faster than that of 3 and 10mm specimens. The difference of crack growth rates can be successfully explained by considering the different stress state of plane strain and plain stress due to the variation of specimen thickness. Also the crack opening ratio of 25mm specimen is greater than those of 3 and 10mm specimens. When a side groove is introduced in a 10mm specimen, the crack growth rate is approximately similar to that of 25mm specimen. The effective thickness expression of $B_e=B_o-(B_o-B_N)^2B_o$ is the most appropriate to evaluate the crack growth rate of side-grooved specimen. Fatigue crack growth rates can be well described by $\Delta K_{eff}$ of the crack closure points in regardless of all thickness and side-grooved specimens.