• Proceedings of the PSK Conference
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• 2002.10a
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• pp.86-87
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• 2002

Recent technological innovations in the drug discovery process such as combinatorial synthesis and high throughput screening have led to the identification of an increasingly large number of compounds at the hits-to-leads stage. Therefore, rapid and precise pharmacokinetic/metabolic screening is essential to enhance the tractability of selected leads and to minimize the risk of failure in the later stages of drug development. (omitted)

• Proceedings of the KOR-KST Conference
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• 1998.02a
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• pp.39-73
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• 1998

• Transportation Technology and Policy
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• v.7 no.4
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• pp.57-65
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• 2010

• Bulletin of the Korean Chemical Society
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• v.17 no.7
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• pp.575-577
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• 1996

• Journal of the Korean Association of Geographic Information Studies
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• v.15 no.4
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• pp.26-41
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• 2012

It is necessary to manage, forecast and prepare agricultural production based on accurate and up-to-date information in order to cope with the climate change and its impacts such as global warming, floods and droughts. This study examined the applicability as well as challenges of the object-based image analysis method for developing a land cover image classification algorithm, which can support the fast thematic mapping of wide agricultural areas on a regional scale. In order to test the applicability of RapidEye's multi-temporal spectral information for differentiating agricultural land cover types, the integration of other GIS data was minimized. Under this circumstance, the land cover classification accuracy at the study area of Kimje ($1300km^2$) was 80.3%. The geometric resolution of RapidEye, 6.5m showed the possibility to derive the spatial features of agricultural land use generally cultivated on a small scale in Korea. The object-based image analysis method can realize the expert knowledge in various ways during the classification process, so that the application of spectral image information can be optimized. An additional advantage is that the already developed classification algorithm can be stored, edited with variables in detail with regard to analytical purpose, and may be applied to other images as well as other regions. However, the segmentation process, which is fundamental for the object-based image classification, often cannot be explained quantitatively. Therefore, it is necessary to draw the best results based on expert's empirical and scientific knowledge.

• Korean Journal of Agricultural Science
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• v.39 no.1
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• pp.97-110
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• 2012

This study was carried out for safety evaluation, the practical application and improvement of design method of the agricultural reservoir embankment according to backside extension. Seepage analysis, slope stability analysis and finite element analysis were performed for steady state and transient conditions. Also, the pore water pressure, seepage quantity, safety factor and stress-strain behavior according to high water level and rapid drawdown were compared and analyzed. The pore water pressure at contact region between backside extension and old embankment was kept high after rapid drawdown. Therefore, backside extension is recommended that design method is required to be improved and reinforced more than the others raising embankment. The hydraulic gradients before and after backside extension showed high value at the base of the core, but they showed stable state at the upstream slope and downstream slope. The seepage quantity per 1 day and the leakage per 100 m for the steady state and transient conditions appeared to be safe against the piping. The safety factor of slope stability showed high at the steady state, and transient conditions did not show differences depending on the rapid drawdown. The safety factor was appeared high at the upstream slope before backside extension and downstream slope after extension. The excess pore water pressure for steady state and transient conditions showed negative(-) at the upstream slope, it was small at the downstream slope. The mean effective stress (p') showed high at the base of the core and to be wild distribution after the extension. The displacement after extension showed 0.02-0.06 m in the upstream slope, the maximum shear strain after extension was smaller than that before extension.

• Analytical Science and Technology
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• v.24 no.4
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• pp.266-274
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• 2011

Using a Hitachi LaChrom Ultra 2000U, a reverse phase ultra high performance liquid chromatography (u-HPLC) method was developed for the rapid quantification of 14 PAHs in foods. The proposed method for PAH analysis is based on solid phase extraction (SPE) cartridges; the determination was carried out by u-HPLC with fluorimetric detection. The method was very sensitive; PAH concentration levels were in a low ${\mu}g$/kg range and could be detected and quantified. Six samples of food were analyzed. Among PAHs, PHE was found in most of samples, the concentration ranging from 2.5 to 19.9 ${\mu}g$/kg. The contents of benzo[c]fluorine (BCL), pyrene (PYR), benzo[a]anthracene (BaA), chrysene (CHR), benzo[b]fluoranthene (BbF), benzo[k]fluoranthene (BkF) were low at the '${\mu}g$/kg' level or were less than LOD.

• Plant Biotechnology Reports
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• v.3 no.1
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• pp.87-93
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• 2009

To determine whether pattern recognition based on metabolite fingerprinting for whole cell extracts can be used to discriminate cultivars metabolically, leaves and fruits of five commercial strawberry cultivars were subjected to Fourier transform infrared (FT-IR) spectroscopy. FT-IR spectral data from leaves were analyzed by principal component analysis (PCA) and Fisher's linear discriminant function analysis. The dendrogram based on hierarchical clustering analysis of these spectral data separated the five commercial cultivars into two major groups with originality. The first group consisted of Korean cultivars including 'Maehyang', 'Seolhyang', and 'Gumhyang', whereas in the second group, 'Ryukbo' clustered with 'Janghee', both Japanese cultivars. The results from analysis of fruits were the same as of leaves. We therefore conclude that the hierarchical dendrogram based on PCA of FT-IR data from leaves represents the most probable chemotaxonomical relationship between cultivars, enabling discrimination of cultivars in a rapid and simple manner.

• Journal of Industrial Technology
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• v.21 no.B
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• pp.249-256
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• 2001

The purpose of this study was to remove the excessive air foaming which was produced in mixing the RSLMC(latex-modified concrete with rapid-setting cement) by choosing the best antifoam agent type. A series of RSLMM(latex-modified mortar with rapid-setting cement) experiments were carried out as a basic experiments for RSLMC with the main experimental variables such as antifiamer types(A, B, C, D), antifoamer contents(0, 1, 2, 3%), and latex contents(10, 15%). Air content test and compressive strength tests were carried out to measure the improved properties of RSLMM. SEM analysis, also, was carried to observe the formation of latex film. The results of RSLMM showed that the decrease of 50% air content was obtained by admixturing an antifoam agent by 1%. This made the strength enhanced and the workability be within the purposed. The best properties of compressive strengths was obtained at latex content of 15% and D antifoam agent of 1%. compressive strength increased about 32.6%. The analysis of SEM results no difference in a formation of later film.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.23 no.4
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• pp.366-375
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• 2001

Bone shaving for surgical correction is general method in facial asymmetrical patient with fibrous dysplasia. Therefore, decision of bone shaving amount on the preoperative planning is very difficult for improvement of ideal occlusal relationship and harmonious face. Preoperative planning of facial asymmetry with fibrous dysplasia is generally confirmed by the simulation surgery based on evaluation of clinical examination, radiographic analysis and analysis of facial study model. However, the accurate postoperative results can not be predicted by this method. By using the computed tomography based RP(rapid prototyping) model, simulation of facial skeleton can be duplicated and 3-dimensional simmulation surgery can be perfomed. After fabrication of postoperative study model by preoperactive bone shaving, preoperative and postoperactive surgical index was made by omnivaccum and clear acrylic resin. Amount of bone shaving is confirmed by superimposition of surgical index at the operation. We performed the surgical correction of facial asymmetry patients with fibrous dysplasia using surgical index and prototyping model and obtained the favorable results.