• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2000년도 추계학술발표대회 논문집
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• pp.119-123
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• 2000

The characteristics of fatigue life distribution for Carbon/epoxy composite laminates was investigated under tension-tension loading(R=0.1). The statistical nature of the fatigue life of the composite materials was analyzed by Weibull, normal, lognormal distributions As a result, it was observed that the correlation between the experimental results and the theoretical predictions for the fatigue life is good. The distribution of the static ultimate strength has the characteristic of lognormal distribution and distribution of the fatigue life has characteristics of the weibull distribution.

• Asian-Australasian Journal of Animal Sciences
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• 제29권6호
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• pp.759-767
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• 2016

The aim of this study was to compare two random regression models (RRM) fitted by fourth ($RRM_4$) and fifth-order Legendre polynomials ($RRM_5$) with a lactation model (LM) for evaluating Holstein cattle in Brazil. Two datasets with the same animals were prepared for this study. To apply test-day RRM and LMs, 262,426 test day records and 30,228 lactation records covering 305 days were prepared, respectively. The lowest values of Akaike's information criterion, Bayesian information criterion, and estimates of the maximum of the likelihood function (-2LogL) were for $RRM_4$. Heritability for 305-day milk yield (305MY) was 0.23 ($RRM_4$), 0.24 ($RRM_5$), and 0.21 (LM). Heritability, additive genetic and permanent environmental variances of test days on days in milk was from 0.16 to 0.27, from 3.76 to 6.88 and from 11.12 to 20.21, respectively. Additive genetic correlations between test days ranged from 0.20 to 0.99. Permanent environmental correlations between test days were between 0.07 and 0.99. Standard deviations of average estimated breeding values (EBVs) for 305MY from $RRM_4$ and $RRM_5$ were from 11% to 30% higher for bulls and around 28% higher for cows than that in LM. Rank correlations between RRM EBVs and LM EBVs were between 0.86 to 0.96 for bulls and 0.80 to 0.87 for cows. Average percentage of gain in reliability of EBVs for 305-day yield increased from 4% to 17% for bulls and from 23% to 24% for cows when reliability of EBVs from RRM models was compared to those from LM model. Random regression model fitted by fourth order Legendre polynomials is recommended for genetic evaluations of Brazilian Holstein cattle because of the higher reliability in the estimation of breeding values.

• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.185-190
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• 2014

Influence of loneliness on human survival has been established epidemiologically, but genomic research remains undeveloped. We identified 34 loneliness-associated genes which were statistically significant for high-lonely and low-lonely individuals. With the univariate Cox proportional hazards regression model, we obtained corresponding regression coefficients for loneliness-associated genes fo individual cancer patients. Furthermore, risk scores could be generated with the combination of gene expression level multiplied by corresponding regression coefficients of loneliness-associated genes. We verified that high-risk score cancer patients had shorter mean survival time than their low-risk score counterparts. Then we validated the loneliness-associated gene signature in three independent brain cancer cohorts with Kaplan-Meier survival curves (n=77, 85 and 191), significantly separable by log-rank test with hazard ratios (HR) >1 and p-values <0.0001 (HR=2.94, 3.82, and 1.78). Moreover, we validated the loneliness-associated gene signature in bone cancer (HR=5.10, p-value=4.69e-3), lung cancer (HR=2.86, p-value=4.71e-5), ovarian cancer (HR=1.97, p-value=3.11e-5), and leukemia (HR=2.06, p-value=1.79e-4) cohorts. The last lymphoma cohort proved to have an HR=3.50, p-value=1.15e-7. Loneliness-associated genes had good survival prediction for cancer patients, especially bone cancer patients. Our study provided the first indication that expression of loneliness-associated genes are related to survival time of cancer patients.

• 대한토목학회논문집
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• 제33권4호
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• pp.1693-1705
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• 2013

국내의 수로교는 쌀문화로 상징되는 농업용수를 공급하는 교량으로서 수로교를 개보수하기 위해서는 기본설계를 실시하는 것이 바람직하나 현재 생략되고 있는 실정이므로 이에 소요되는 공사비를 산정할 필요가 있다. 이 연구에서는 2003년 이후 교체한 RC구조 수로교에 대한 실적자료를 기초로 개략공사비 산정 회귀분석(RA) 모델과 사례기반추론(CBR) 모델을 개발하였다. RA 모델의 경우 단순회귀 모델이 다중회귀 모델보다 오차율이 낮았다. CBR 모델의 경우 유전 알고리즘을 이용하였으며 영향요인의 가중치, 편차, 순위조건을 최적화 대상으로 하였고 특히 영향요인 가중치의 범위를 제한하여 수로교 개보수 공사비의 예측 정확도를 제고하였다. RA 모델과 CBR 모델 사이의 오차율은 통계적 차이를 보이지 않았다. 본 논문에서 제시된 수로교 개보수 개략공사비 산정방법은 개보수사업의 시행에 따른 신속한 의사결정을 하는데 활용될 수 있을 것으로 기대된다.

• Journal of Animal Science and Technology
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• 제47권2호
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• pp.147-158
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• 2005

The purpose of this study was to find out the effects that daughters' incomplete lactation records affect sire's breeding values through genetic evaluation using RRTDM(random regression test-day model). First, we estimated genetic parameters and breeding values on sires having complete lactation records of daughter by RRTDM, second, we changed complete lactation records of specific sires into incomplete records by various methods. Third, the breeding values were compared between complete and incomplete records. Finally, this study aimed to find out the methods to minimize the estimation errors of young bulls' breeding values. Data used in this study were collected from the dairy herd improvement program, and a total of 97,562 records were composed of 10,929 first parity with both parents known, since 1999. Breeding values on the daughters from randomly chosen sires were calculated and compared with among 90 day, 150day, and 200 day's incomplete records. For milk yields, sire's ranks of breeding values used by complete lactation records were very different from sire's ranks of breeding values obtained by incomplete lactation records(Rank_90 cut, 150cut, 200 cut).The differences were also obtained between complete lactation records(per305_full) and incomplete lactation record (per_90 cut, 150cut, 200 cut) in breeding values regarding persistency. Especially, the differences between per_90 cut and per305_full were very large(from 1.8 kg to 145kg).

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제44권1호
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• pp.25-28
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• 2018

Objectives: This study aimed to describe recent patterns in the types of statistical test used in original articles that were published in Journal of the Korean Association of Oral and Maxillofacial Surgeons. Materials and Methods: Thirty-six original articles published in the Journal in 2015 and 2016 were ascertained. The type of statistical test was identified by one researcher. Descriptive statistics, such as frequency, rank, and proportion, were calculated. Graphical statistics, such as a histogram, were constructed to reveal the overall utilization pattern of statistical test types. Results: Twenty-two types of statistical test were used. Statistical test type was not reported in four original articles and classified as unclear in 5%. The four most frequently used statistical tests constituted 47% of the total tests and these were the chi-square test, Student's t-test, Fisher's exact test, and Mann-Whitney test in descending order. Regression models, such as the Cox proportional hazard model and multiple logistic regression to adjust for potential confounding variables, were used in only 6% of the studies. Normality tests, including the Kolmogorov-Smirnov test, Levene test, Shapiro-Wilk test, and $Scheff{\acute{e}}^{\prime}s$ test, were used diversely but in only 10% of the studies. Conclusion: A total of 22 statistical tests were identified, with four tests occupying almost half of the results. Adoption of a nonparametric test is recommended when the status of normality is vague. Adjustment for confounding variables should be pursued using a multiple regression model when the number of potential confounding variables is numerous.

• 한국콘텐츠학회논문지
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• 제15권5호
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• pp.475-487
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• 2015

본 연구에서는 부트스트랩 DEA를 이용하여 2013년 14개 공기업의 경영 효율성을 분석하였다. 또한 단절회귀분석을 이용하여 부트스트랩 편의조정 효율성에 영향을 미치는 요인을 분석하였다. 본 연구를 통해 도출된 결과와 시사점을 정리하면 다음과 같다. 첫째, 부트스트랩 DEA모형을 적용한 효율성 분석결과에 따르면 평균 기술효율성이 0.3182, 평균 순수기술효율성이 0.4994, 평균 규모효율성이 0.6585로 나타났으며, 기술비효율성의 주된 원인이 순수기술비효율성에 기인하는 것으로 분석되었다. 둘째, CRS 가정과 VRS 가정하의 일반 DEA모형을 적용한 TE와 부트스트랩 DEA모형을 적용한 TE 순위간에는 유의한 차이가 없는 것으로 나타났다. 셋째, 비효율원인 분석에서는 평가대상 14개 기관 중 11개 기관의 비효율원인이 순수기술에 더 크게 기인하고 있고, 3개 기관이 규모효율에 의해 비효율이 나타나는 것으로 분석되었다. 넷째, 단절회귀분석에서는 규모효율성에 영향을 미치는 요인으로 유의수준 10%에서 인건비, 영업이익, 매출액, 자기자본수익률, 종원원수 순으로 나타났다.

• 재활복지
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• 제18권4호
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• pp.95-117
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• 2014

본 연구는 활동보조서비스(신체활동지원, 가사활동지원, 사회활동지원) 이용이 가족부양부담에 영향을 미치는지와 활동보조서비스와 가족 부양부담감 간에 가족탄력성(가족신념체계, 가족응집력, 상호작용)이 조절효과를 나타내는지를 파악하여 장애인복지의 실천적 개입 방안을 모색하는 근거자료를 제시하는데 목적이 있다. 본 연구의 연구목적을 위하여 경기도를 동부, 서부, 남부, 북부 지역으로 나누어서 2013년 4월 1일~5월 15일까지 활동보조서비스를 이용하는 1급, 2급 장애인가족 부양자 200명을 대상으로 자료를 수집하여 분석하였다. 자료분석은 spss 19.0 통계프로그램을 이용하여 탐색적 요인분석과 확인적 요인분석 그리고 위계적 회귀분석을 기초로 한 조절적 다중회귀분석(Moderated Multiple Regression Analysis)을 실시하였다. 본 연구의 주요 연구결과는 첫째, 활동보조서비스 중 신체활동지원을 이용하는 경우 장애인가족의 부양부담 감소에 영향을 주는 것으로 나타났다. 둘째, 활동보조서비스가 가족부양부담과의 관계에서 가족탄력성 중 가족신념체계와 가족응집력에서 조절효과가 있는 것으로 분석되었다.

• Journal of the Korean Physical Society
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• 제80권
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• pp.247-256
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• 2022

Our objective was to investigate radiomics signatures and prediction models defined by four segmentation methods in using 2-[¹⁸F]fluoro-2-deoxy-d-glucose positron emission tomography (¹⁸F-FDG PET) imaging of lung metastases of soft-tissue sarcomas (STSs). For this purpose, three fixed threshold methods using the standardized uptake value (SUV) and gradient-based edge detection (ED) were used for tumor delineation on the PET images of STSs. The Dice coefficients (DCs) of the segmentation methods were compared. The least absolute shrinkage and selection operator (LASSO) regression and Spearman's rank, and Friedman's ANOVA test were used for selection and validation of radiomics features. The developed radiomics models were assessed using ROC (receiver operating characteristics) curve and confusion matrices. According to the results, the DC values showed the biggest difference between SUV40% and other segmentation methods (DC: 0.55 and 0.59). Grey-level run-length matrix_run-length nonuniformity (GLRLM_RLNU) was a common radiomics signature extracted by all segmentation methods. The multivariable logistic regression of ED showed the highest area under the ROC (receiver operating characteristic) curve (AUC), sensitivity, specificity, and accuracy (AUC: 0.88, sensitivity: 0.85, specificity: 0.74, accuracy: 0.81). In our research, the ED method was able to derive a significant model of radiomics. GLRLM_RLNU which was selected from all segmented methods as a meaningful feature was considered the obvious radiomics feature associated with the heterogeneity and the aggressiveness. Our results have apparently showed that radiomics signatures have the potential to uncover tumor characteristics.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.4079-4083
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• 2014

Background: Previous studies have showed that argonaute 2 is a potential factor related to genesis of several cancers, however, there have been no reports concerning gliomas. Methods: Paraffin specimens of 129 brain glioma cases were collected from a hospital affiliated to Binzhou Medical University from January 2008 to July 2013. We examined both argonaute 2 mRNA and protein expression by real-time quantitative PCR (qRT-PCR), Western blot analysis, and immunohistochemistry (IHC). The survival curves of the patients were determined using the Kaplan-Meier method and Cox regression, and the log-rank test was used for statistical evaluations. Results: Both argonaute 2 mRNA and protein were upregulated in high-grade when compared to low-grade tumor tissues. Multivariate analysis revealed that argonaute 2 protein expression was independently associated with the overall survival (HR=4.587, 95% CI: 3.001-6.993; P=0.002), and that argonaute 2 protein expression and WHO grading were independent prognostic factors for progression-free survival (HR=4.792, 95% CI: 3.993-5.672; P<0.001, and HR=2.109, 95% CI: 1.278-8.229; P=0.039, respectively). Kaplan-Meier analysis with the log-rank test indicated that high argonaute 2 protein expression had a significant impact on overall survival (P=0.0169) and progression-free survival (P=0.0324). Conclusions: The present study showed that argonaute 2 expression is up-regulated in gliomas. Argonaute 2 might also serve as a novel prognostic marker.