• 제목/요약/키워드: Randomized

검색결과 5,105건 처리시간 0.03초

불면증 무작위배정 임상시험에 대한 문헌 고찰 (Literature Review of Randomized Clinical Trials Regarding Insomina)

  • 박혜주;유종향;권지혜;이시우
    • 동의신경정신과학회지
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    • 제24권3호
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    • pp.201-210
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    • 2013
  • Objectives : To review the recent trend of randomized controlled clinical trials on insomnia and to provide information for future clinical trials. Methods : A total of 667 pieces of literature were searched using the key words 'insomnia' and 'randomized controlled trial' and using the title 'insomnia' with the topic 'trial or trials', published from 2008 to 2012 through Web of Science. Studies including randomized controlled clinical trials were sorted from the search result and finally 104 pieces of the literature were selected and examined. Results : Besides 104 clinical trials, 14 trials related to CAM (Complementary and Alternative Medicine) were also reviewed. On average, 20 trials were annually conducted and they showed a growing trend. Participants were between 31 and 90 (34.6%), and were observed for less than 30 days (28.8%) in most trials. As intervention methods for clinical trials, non-pharmaceutical methods were used in 59 studies (56.7%), pharmaceutical drug in 43 studies (41.3%) and combinations in 2 studies (1.9%). In 60 studies, only insomnia without any underlying diseases was examined and other 44 studies involved other diseases. As diagnosis assessment tools, Sleep diary and Polysomnography were used. Conclusions : Randomized controlled trials relevant to insomnia were on the increase, but only a small number of clinical trials on Oriental Medicine have been performed. Larger scientific and well-founded randomized controlled trials are required for developing Oriental Medicine and establishing high-quality guideline going forward.

네트워크 분석을 이용한 불면의 무작위임상시험 해외 연구 동향 (Research Trends of Randomized Clinical Trial for Insomnia Using the Network Analysis)

  • 백영화;진희정
    • 한국콘텐츠학회논문지
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    • 제13권12호
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    • pp.1036-1047
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    • 2013
  • 본 연구는 불면과 관련된 무작위임상시험의 해외 연구 동향을 살펴보기 위하여 시계열적 키워드 비교 분석 및 네트워크 분석을 실시하였다. 분석에 사용된 자료는 'Insomnia'와 'Randomized Clinical Trial'의 연관 키워드를 사용하여 ClinicalTrials의 379건, Web of Science의 132건을 선정하였다. 분석 결과, ClinicalTrials에서는 불면과 약물요법을 중심으로 인지행동요법, 우울 등의 키워드가 네트워크를 이루고 있었다. WOS에서는 ClinicalTrials의 결과에 멜라토닌 키워드가 추가적으로 나타났다. 또한, 연구 대상자 중 특징적으로 노인과 여성에 대한 연구가 꾸준히 진행되는 것으로 파악되었다.

농업인을 대상으로 한 운동프로그램 관련 국내 임상연구에 대한 체계적 문헌고찰 (Domestic Clinical Studies Related to the Exercise Program Targeting Farmers : a Systematic Review)

  • 국길호;이은정;오민석
    • 한방재활의학과학회지
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    • 제21권4호
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    • pp.77-86
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    • 2011
  • Objectives: This study aims to evaluate domestic clinical studies related to the exercise program targeting farmers. Methods: Five Korean databases were seamed for prospective clinical trials of exercise program targeting farmers from 2001 to August, 2011. Only studies conducted in Korean language were searched. Results: Thirteen clinical studies were included among 3374 studies searched. Six were observational studies, four were non-randomized controlled trials, and three were randomized controlled trials. All of included studies reported favorable effects of exercise group compared to baseline of controlled group. Conclusions: We found various mistake in the applications of statistical methodologies in the studies of exercise program targeting farmers. It is necessary for more randomized controlled trials to evaluate effect of exercise program target farmers.

A CONDITIONAL UNRELATED QUESTION RANDOMIZED RESPONSE MODEL

  • Lee, Gi-Sung;Hong, Ki-Hak
    • Journal of applied mathematics & informatics
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    • 제8권1호
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    • pp.253-260
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    • 2001
  • In this paper we suggest a conditional unrelated question randomized response model by using the Carr et. al.’s model(1982) and Greenberg et. al.’s model(1969). Our model can obtain more comprehensive information about the sensitive character A. We suggest the conditions that make our model efficient compared with models of Greenberg et. al. and Carr et al..

Nonparametric Procedures for Comparing Ordered Treatment Effects with a Control in a Randomized Block Design

  • Lim, Dong-Hoon
    • Journal of the Korean Statistical Society
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    • 제26권1호
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    • pp.89-100
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    • 1997
  • In this paper we are concerned with comparing ordered treatment effects with a control in a randomized block design with multiple observations per cell. Two nonparametric procedures for detecting which treatment are better than the control are proposed and compared. An example is given and the results of a Monte Carlo power study are discussed.

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무관질문형 다지확률응답모형에서의 베이즈 선형추정량에 관한 연구 (A Bayes Linear Estimator for Multi-proprotions Randomized Response Model)

  • 박진우
    • 응용통계연구
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    • 제6권1호
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    • pp.53-66
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    • 1993
  • 다지확률응답모형인 경우에 대한 베이지안 접근방법을 연구하였다. O'Hagan (1987)의 베이 즈 선형추정량을 다지확률 응답모형의 경우로 확장하였다. 한편 수치비교방법에 의해 새로 이 연구된 베이즈 선형 추정량과 기존의 최대우도추정량과의 효율을 비교해 보았다. 이때 베이지안 방법의 사전분포로는 Dirichlet 분포를 사용하였다.

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Randomized Response Model with Discrete Quantitative Attribute by Three-Stage Cluster Sampling

  • Lee, Gi-Sung;Hong, Ki-Hak
    • Journal of the Korean Data and Information Science Society
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    • 제14권4호
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    • pp.1067-1082
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    • 2003
  • In this paper, we propose a randomized response model with discrete quantitative attribute by three-stage cluster sampling for obtaining discrete quantitative data by using the Liu & Chow model(1976), when the population was made up of sensitive discrete quantitative clusters. We obtain the minimum variance by calculating the optimum number of fsu, ssu, tsu under the some given constant cost. And we obtain the minimum cost under the some given accuracy.

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A Combined Procedure of Direct Question Method and Modified Randomized Response Technique for Estimating Population Proportion

  • Kim, Hyuk-Joo
    • Journal of the Korean Data and Information Science Society
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    • 제14권4호
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    • pp.877-887
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    • 2003
  • A two-stage procedure is proposed to estimate the population proportion of a sensitive group. The proposed procedure is obtained by combining the direct question method and a modified randomized response technique. It is verified that the proposed procedure is more efficient than existing methods under some mild conditions.

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A Conditional Randomized Response Model for Detailed Survey

  • Lee, Gi-Sung;Hong, Ki-Hak
    • Communications for Statistical Applications and Methods
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    • 제7권3호
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    • pp.721-729
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    • 2000
  • In this paper, we propose a new conditional randomized response model that has improved the Carr et al.'s model in view of he variance and the protection of privacy of respondents. We show that he suggested model is more effective and protective than the Loynes' model and Carr et al.' model.

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A Bayesian Analysis of the Multinomial Randomized Response Model Using Dirichlet Prior Distribution

  • Kim, Jong-Min;Heo, Tae-Young
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2005년도 춘계 학술발표회 논문집
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    • pp.239-244
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    • 2005
  • In this paper, we examine the problem of estimating the sensitive characteristics and behaviors in a multinomial randomized response (RR) model. We analyze this problem through a Bayesian perspective and develop a Bayesian multinomial RR model in survey study. The Bayesian inference of multinomial RR model is a new approach to RR models.

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