• 대한한의학회지
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• 제32권5호
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• pp.114-125
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• 2011

Objectives: The aim of this study was to evaluate the efficacy of microcurrent taping therapy and kinesio taping therapy. Methods: We included 58 participants who met the inclusion criteria and assigned them into two groups after the randomization. We allocated 29 participants to the microcurrent taping therapy group (MCT) and the other 29 to the general kinesio taping therapy group (GT). 27 participants completed the trial in the MCT group, 27 participants in GT. We attached "I" shaped 20cm tape along the erector muscle of the spine starting from the level of S2, and another 30cm tape on the iliac crest horizontally. These "I" shaped tapes were attached on two parts of the body and were performed the same way for both groups. This procedure was done 8 times and participants visited a total of 9 times including a final visit for evaluation. We measured Visual Analog Scale (VAS), Range of Motion (ROM) and Schober's test on every visit. Participants completed a questionnaire of Oswestry Disability Index (ODI) and Beck's Depression Inventory (BDI) on the first and last visits. Results & Conclusion: There was a significant effect of microcurrent taping therapy on lower back pain, but we could not establish the superior effect of microcurrent taping therapy compared with general kinesio taping therapy.

• 한방재활의학과학회지
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• 제19권2호
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• pp.261-273
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• 2009

Objectives : This study was performed to figure out the effects of herbal mesotherapy on abdominal fat in obese women. Methods : Forty obese women those who were diagnosed abdominal obesity had been recruited during February, 2008. They were randomly assigned experimental or control group under block-randomization. Experimental group were treated with Sobi-eum(Xiaofei-yin) injection during 6 weeks (2 times a week) and placebo group were treated with normal saline injection under same procedures. Anthropometry, body impedance analysis, fat computed tomography, blood test, and questionnaires had been administered before and after the treatment. Results : Four subjects were dropped out (voluntary give up), so 18 in experimental group and 18 in placebo group were evaluated. There were significant changes after treatments in both groups. Although no significant differences have been found in the result of anthropometry, body impedance analysis and fat computed tomography between two groups, in the experimental group, the changes of total fat area had a highly significant relationship with all part of abdominal fat. While the placebo group had highly significant relationships with subcutaneous fat area, superficial and deep subcutaneous fat area but not with visceral fat area. Conclusions : Compaired with saline group, herbal mesotheraphy Sobi-eum(Xiaofei-yin) is effective in reduction of visceral fat after adjusting TFA.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3333-3340
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• 2010

A three dimensional pharmacophore model was generated for the molecules which are responsible for anti-inflammatory activities targeting Interleukin-2 inducible tyrosine kinase (Itk). 16 structurally diverse molecules were selected as training set to generate the hypotheses using Discovery Studio v2.1. The best hypothesis, Hypo1, comprises two hydrogen bond acceptor (HBA), one hydrophobic aromatic (HA), one ring aromatic (RA) and shows high cost difference (63.71), high correlation coefficient (0.97) as well as low RMS deviation (0.81). Hypo1 has been further validated toward a test set, decoy set and Fischer's randomization method. Furthermore, Hypo1 was used to screen NCI and Maybridge databases. Finally, 2 hit molecules were identified as potential leads against Itk, which may be useful for future drug development.

• 대한간호학회지
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• 제46권6호
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• pp.881-893
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• 2016

Purpose: The purpose of this study was to develop a heart health diary to promote self-care ability among patients with heart failure (HF), and to identify the diary's effect on self-care adherence, self-efficacy, and physical activity. Methods: A randomized control-group pretest-posttest design was adopted using block randomization. A calender-typed health diary was developed and it included a self-care checklist and education information on HF management. The experimental group were given guided counseling and education for 8 weeks and wrote a daily health diary during that period. Data were collected from the outpatient department of a tertiary medical center from February to April 2016. To verify the hypotheses, data for the experimental group (n=28) and control group (n=33) were analysed using the independent t-test with SPSS/WIN 21.0. Results: At the end of 8 weeks the experimental group had significantly higher scores for self-care adherence (t=-2.48, p =.016) and exercise related self-efficacy (t=-3.44, p =.001) compared to the control group. Conclusion: The findings show that the application of a patient-directed heart health diary is an effective nursing intervention for improving HF patients' self-care adherence and exercise self-efficacy. Strategies to promote dietary self-efficacy are necessary along with further studies including repeated research with an increasing intervention period. Healthcare providers need to encourage the utilization of a health diary for HF patients as a tool for evaluation and for implementation that leads to self-care.

• Restorative Dentistry and Endodontics
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• 제46권2호
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• pp.24.1-24.11
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• 2021

Objectives: The present study aimed to evaluate the survival rate and clinical performance of class 1 composite restorations restored with the Filtek Bulk Fill composite material using either the bulk fill technique or the incremental technique at baseline (1 week) and at 3, 6 and 12 months of follow-up. Materials and Methods: Forty-two patients with at least 2 carious teeth were selected. Following randomization, one tooth was restored with the Filtek Bulk Fill composite using the incremental fill technique, and the other tooth was restored with the same material using the bulk fill technique. Patients were recalled for follow-up at baseline (1 week) and 3, 6, and 12 months and evaluated using the FDI criteria. Results: The data were analyzed using the McNemar χ² test. No statistically significant differences were found between the scores of teeth restored with either technique. At baseline and at 3, 6, and 12 months of follow-up; there were no significant difference in the clinical status of both groups of restorations. Conclusions: Within the limitations of this study, using the bulk fill technique for restorations with the Filtek Bulk Fill material seems to be equally efficient to using the incremental fill technique.

• 대한한방체열의학회지
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• 제5권1호
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• pp.46-58
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• 2006

Purpose: We intended to observe the relations between Chiljehyangbuhwan and abdominal & palmar temperature according to primary dysmenorrhea severity. Methods: We selected the 100 primary dysmenorrhea patients by the screening tests (first screening test-inquiry, second screening test-clinical test. additionally WHR (Waist-to-Hip ratio) by Inbody 2.0). By the fixed blocked randomization and double blind method, Chiljehyangbuhwan or placebo was administered for 1 menstration period. Finally, 69 patients remainded. Before and after administration, we measured 4 points abdominal temperature (Chon-jung (CV17), Chung-wan(CV12), Kwan-won(CV4). Chung-guk(CV3)) by DITI(DOREX Inc., USA). And then we checked the difference of temperature $({\Delta}T)$ between CV17 and CV12/CV17 and CV4/CV17 and CV3/CV12 and CV4/CV12 and CV3. Also, we measured 2 points (palmar region, upper front of forearm) for the difference of palmar temperature $({\Delta}T)$. Then, we checked palmar temperature minus upper front of forearm temperature and took an average of right and left ${\Delta}T.$ After that. we compared ${\Delta}T$ with primary dysmenorrhea severity evaluated by VRS (verbal rating scale) and MVRS (multidimensional verbal rating scale). In dysmenorrhea severity. we standardized scale score and 3-group-severity by score (mild, moderate. severe). Besides, we compared palmar ${\Delta}T$ with abdominal ${\Delta}T$. For statistics, we used ANOVA and Spearman's rho correlations. SPSS 13.0 for windows. Results: In case of MVRS, though Chiljehyangbuhwan was correlated to abdominal ${\Delta}T$(CV12 and CV3/CV12 and CV4). it was not correlated to palmar ${\Delta}T$. In case of VRS, though Chiljehyangbuhwan was not correlated to abdominal ${\Delta}T$. it was correlated to palmar ${\Delta}T$. However. palmar ${\Delta}T$ was not correlated to abdominal ${\Delta}T$. Statistically they showed significant result (p<0.05). Conclusion: The primary dysmenorrhea patients showed that severity by MVRS was connected with abdominal ${\Delta}T$ (CV12 and CV3/CV12 and CV4) and severity by VRS was connected with palmar ${\Delta}T$ after Chiljehyangbuhwan administration. So we can consider Chiljehyangbuhwan partially effects the abdominal & palmar temperature according primary dysmenorrhea severity. However, palmar temperature was not correlated to abdominal temperature. Therefore, we need further study.

• 한국산학기술학회논문지
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• 제21권12호
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• pp.253-260
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• 2020

본 연구는 다양한 좌석 높이에서 일어서기 훈련이 뇌졸중환자의 균형에 미치는 영향에 대해 알아보고자 연구를 실시하였다. 연구의 대상자는 뇌졸중환자 20명이며 무작위로 표준좌석 높이 그룹 10명과 낮아지는 좌석높이그룹 10명으로 분류하여 2019년 3월에서 6월까지 주 3회 6주간 훈련을 실시하였다. 정적균형과 동적균형을 측정하였으며 그룹 내 훈련 전·후의 변화를 검증을 위하여 대응표본 t-검정을 실시하고, 그룹 간 훈련 전·후 변화의 차이를 검증하기 위하여 독립표본 t-검정을 실시하였다. 연구 결과, 그룹 내 훈련 전·후의 변화는 정적균형 및 동적 균형 모두 유의한 변화를 보였으나(p<.05), 그룹 간 훈련 전·후 변화량의 차이는 눈 감은 상태의 선자세 정적균형만 유의한 차이를 보이지 않았다(p>.05). 본 연구의 훈련이 뇌졸중 환자의 균형에 유의한 효과가 있음을 확인하였으며 특히, 훈련 시 좌석의 높이를 점진적으로 낮추어 제공하는 것이 뇌졸중 환자의 균형회복을 위한 새로운 치료방법으로 임상에서 활용되어 재활의 다양한 방향성을 제시되었음으로 사료된다. 그리고 연구 결과의 일반화를 위해 추후 연구는 많은 대상자에게 훈련의 적용이 필요하며 좌석 높이의 무작위 조성과 같은 다양한 훈련방법에 관한 연구들이 필요할 것이다.

• 대한지리학회지
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• 제42권4호
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• pp.616-631
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• 2007

거주지 분화 현상은 도시적 삶의 공간성을 파악하는데 본질적인 요소이기 때문에 도시학 연구에서 오랫동안 주목을 받아왔다. 거주지 분화 현상에 대한 연구 과제 중의 하나가 상이한 두 집단이 얼마나 공간적으로 분리되어 있는지를 측정하는 문제이다. 이러한 측면에서 가장 널리 사용되어온 것이 상이지수(index of dissimilarity)인데, 이 지수는 거주지 분리의 '불균등성(unevenness)'은 측정할 수 있지만, 공간적 '집중도(clustering)'는 측정하지 못하는 단점을 갖고 있다. 이러한 단점을 극복하기 위해 제안되어 온 '공간적 격리 지수(spatial indices of segregation)' 역시 가설검정 절차를 제시하지 못하고 최근의 공간통계학 연구 성과를 수용하지 못하는 등의 단점을 가지고 있다. 이러한 의미에서 본 논문의 주된 연구 목적은 새로운 '공간 분리성 측도(spatial separation measure)'를 개발하는 것이다. 이 공간 분리성 측도는 상이한 인구 집단이 거주 공간에 얼마나 불균등하게 분포하고 있는지에 대한 것뿐만 아니라 그러한 불균등 분포가 보여주는 공간적 의존성의 정도까지도 측정하는 새로운 통계량이다. 주요 연구 결과는 다음과 같다. 첫째, 기존의 '공간 연관성 측도(spatial association measures)'와 '공간적 카이-스퀘어 통계량(spatial chi-square statistics)'을 통합하여 새로운 측도를 개발했으며, 일반화된 랜덤화 검정법을 적용해 측도에 대한 유의성 검정법을 제시하였다. 둘째, 개발된 측도와 유의성 검정법을 우리나라 7대 도시의 학력 집단 간 거주지 분리 현상에 적용함으로써, 연구방법론으로서의 유용성을 확인하였다.

• 대한간호학회지
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• 제17권3호
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• pp.204-217
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• 1987

It is generally accepted that the delivery of health care is undergoing many changes specially those related to acute, contagious disease care and to the increase of chronic illnesses which can not be cured but are controlable. The health care practitioner can not be soley responsible for the control of their clients' care. Because the clients will play a vital role in controlling their illnesses, long term participation by both the health care provider and the client is necessary. Since most individuals with hypertension do not experience signs or symptoms, the disease is difficult to detect and even when diagnosed, clients do not comply well with their hypertension regimens. The noncompliant client is at increased risk for compliants involving the heart, brain, kidney and other organs. In an effort to explore methods of increasing patient participation in and adherence to treatment programs for hypertension, the researcher used health contracting to promote self care. The research questions are; 1) Will the health contracting increase compliance in health behavior and reduce the blood pressure\ulcorner 2) If clients comply with their regimens will this reduce their blood pressure\ulcorner The research design utilized in this study was a quasi-experimental design. A purposive sample, was abtained from two churches in the 1. area, consisting of 64 clients with hypertension. The data was collected from the middle of January to the 1st of September 1985. Randomization was only of the two church groups into experimental and control groups. Compliance with health behavior related to the hypertensive regimen, blood pressure and body weight were measured, compared and analyzed. In the experimental group measurements were made 6 times; one month before the education program after education program when health contracting was done and 4 more times once a month for 4 months. In the control group measurements were made 3 times; one month before the education program after the education program, and once 4 months later. There was no health contracting. The data were analyzed by t-test, Pearson correlation and ANOVA according to purpose of the study. The result of this study may be summarized as follows: The result related to the hypothesis on the effect of health contracting are as follows: H$_1$; “The hypothesis that the experimental group, with a health contractual agreement will demonstrate increased compliance levels for health behavior than the control group” was supported(t＝-5.29, df＝62, p＝.000). H$_2$; “The hypothesis that the experimental group, with a health contractual agreement, will demonstrate a greater reduction in blood pressure than the control group” was supported (for systolic blood pressure t＝2.72, df＝62, p＝.009, for diastolic blood pressure t＝1.95, df＝62, p＝.050). H$_3$; The hypothesis that the greater the compliance of the client with health behavior the lower the client's blood pressure will be was partially supported (for systolic pressure r＝-.2981, p＝.008, for diastolic pressure r＝-.1720, p＝.087). From the examination of the results of this study it can be concluded that the interaction between the nurse and the client, contracting to define goals and reinforcing compliant behavior, leads to improved compliance with health care behaviors and thus to an increase in the effectiveness of nursing care. Further consideration need to be given to the inclusion of the concept of health contracting in primary nursing and to further research in this area.

• 생명과학회지
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• 제28권11호
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• pp.1262-1267
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• 2018

국지적 환경에서 패치 분포 형태는 일차적으로 식물의 공간적 양상으로 나타나고, 임의화 과정은 패치를 결정하는 공간적 가설을 입증하는데 이용된다. 주름조개풀(Oplismenus undulatifolius (Ard.) P. Beauv. var. undulatifolius)은 Poaceae과 Oplismenus 속에 속하는 초본류이다. 이 종은 온대, 아열대, 열대에 분포한다. 이 지역의 주름조개풀이 일정한 분포인지 응집하는 분포인지 여러 패치 지표를 사용하여 분석하였다. 한우산의 집단 밀도는 0.453에서 4.375였으며 평균은 2.387이였다. 소형과 중형 프롯($2m{\times}2m$, $2m{\times}4m$, $4m{\times}4m$, $4m{\times}8m$, and $8m{\times}8m$)에서 주름조개풀은 응집형태를 보였다. 반면에 대형 플롯($8m{\times}16m$, $16m{\times}16m$, and $16m{\times}32m$)에서는 일정한 분포 양상을 나타내었다. 평균 응집 계수(M*)와 패치 지표(PAI)는 양의 값을 보였다. 응집은 여러 환경적 요인에 기인하는데 등산객들에 의해 방해되고 있었다. 따라서 주름조개풀은 이 지역에서 본래의 기본 생태적 지위를 누리지 못하고 있음을 보여주었다.