• Archives of design research
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• no.16
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• pp.17-25
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• 1996

, \l!ernatives in multi dimensional decision prohlems generally possess numerous attrihutes by which they can be describ('d and compared, The ('\';dllation factors include all attributes that have Ic\'(']s specified by quantitative and qualitativc objectil'l'S, Howev'('f since qualitative factors arc difficul! to quantify as num('ral estimates, these factors have tended to bl' ignored without regard for their importance to human contrnl. In this study, the author adapted :j ('va]uation methods with critrria which have qualitative and qualitative attributes: the Intuitive Evaluation ~1cthods the Accumulativc' Evaluation Model the Benchmarking Evaluation Methods, and studied the corrC'iation between them, The results show that Ill(' :j Mrthods have reciprocal relationships under reliability (r=O, (XX)]] In order to removl' obstacles of desi!;n ev'aluation ( lots of timl' l'llnsumption, constr;lints of placc" difficulties of hu!;!' data procc'ssin!;), it is necessary to be developed a new ('va]uation syst('rn which could prov'idc' effective rat in!; of desi!;n v'alm's 10 make value judw'rnents, , \l!ernatives in multi dimensional decision prohlems generally possess numerous attrihutes by which they can be describ('d and compared, The ('\';dllation factors include all attributes that have Ic\'(']s specified by quantitative and qualitativc objectil'l'S, Howev'('f since qualitative factors arc difficul! to quantify as num('ral estimates, these factors have tended to bl' ignored without regard for their importance to human contrnl. In this study, the author adapted :j ('va]uation methods with critrria which have qualitative and qualitative attributes: the Intuitive Evaluation ~1cthods the Accumulativc' Evaluation Model the Benchmarking Evaluation Methods, and studied the corrC'iation between them, The results show that Ill(' :j Mrthods have reciprocal relationships under reliability (r=O, (XX)]] In order to removl' obstacles of desi!;n ev'aluation ( lots of timl' l'llnsumption, constr;lints of placc" difficulties of hu!;!' data procc'ssin!;), it is necessary to be developed a new ('va]uation syst('rn which could prov'idc' effective rat in!; of desi!;n v'alm's 10 make value judw'rnents,alm's 10 make value judw'rnents,

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.3
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• pp.65-71
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• 2008

Purpose: This paper studied the effect of eyes on the comparison between the distance optical centers problem of dispensing reading glasses made by optician and finished reading glasses in the current market. Methods: The method of this study has been measured by eleven different categories from +1.00D to +4.00D. This study also separated into three groups by their optical frame size and measured optical center point (O.C) and optical center height (O.H) with 200 peoples of man and females over 40 years old without ocular disease living in Gwang-san gu, Gwang-Ju city. Results: As a result, optical center point ranged from 57 mm to 80 mm and it turned to be most common range is from 61 mm to 65 mm (64.6%). Moreover, the optical center height ranged from 1 mm to 8mm and most common ranged (23%) were 4 mm. In other words, finished reading glasses have irregular optical ranges. After observing 200 people who are over 40 years old men and women, result shows that more than 75.5% (151 people) currently use finished reading glasses. Survey of 151 people, most common error between the finished reading glasses's O.C and the wearers P.D were 4 mm (45%). Furthermore, the most common error between the finished reading glassses's O.H and the wearers O.H ranged from 3 mm to 4 mm. Astonishingly, the entire 151 people who wear finished reading glasses appeal that they feel tiredness on their eyes when they wear finished reading glasses. 53 people (35%) claimed that they feel tiredness on their eyes after 10 to 20 minutes wearing finished reading glasses. Base on the research, We conducted more experiment to find the value of prism of optical centers err because it will tell us whether the finished reading glasses are good enough to wear or not. We multiplied diopter by the difference between finished reading glasses's O.C. and wearer's P.D. Consequently, We found out that the finished reading glasses counter to the German RAL-RG 915 policy. And We also found that it is relative to the diopter of lenses. In conclusion, based on the researched that wearing finished reading glasses have a dangerous factor for our vision. Therefore optician must need to recommend correctly made dispensing reading glasses based on the optical center point.

• Proceedings of the IEEK Conference
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• 2001.06d
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• pp.89-92
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• 2001

In this paper, we propose a new approach for tracking a moving object in moving image sequences using active contour models and optical flow. In our approach object segmentation is achieved by active contours, and object tracking is done by motion estimation based on optical flow. To get more dynamic characteristics, Lagrangian dynamics combined to the active contour models. For the optical flow computation, a method, which is based on Spatiotempo-ral Energy Models, is employed to perform robust tracking under poor environments. A prototype real tracking system has been developed and applied to a contents-based video retrieval systems.

• Biomedical Science Letters
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• v.15 no.4
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• pp.327-333
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• 2009

Heterotrimeric GTP binding proteins, G-proteins, mediate signal transduction generated by neurotransmitters and hormones. Among G-proteins, Go proteins are the most abundant in brain and classified as a member of Gi family. Ras-like protein in all tissues (Rit), one of the small GTPases, is a member of a Ras superfamily and identified as an important regulator of neuronal differentiation and cell transformation. Recently, we have reported that Rit functioned as a candidate downstream effector for alpha subunit of Go proteins ($Go{\alpha}$) and regulated neurite outgrowth triggered by $Go{\alpha}$ activation. In this study, we showed that the GTPase domain of $Go{\alpha}$ contributed to the direct interaction with Rit. We also demonstrated that $Go{\alpha}$ could lead to an increase of Rit activity suggesting that Rit play a role as a downstream effector of $Go{\alpha}$.

• Biomolecules & Therapeutics
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• v.25 no.1
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• pp.26-43
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• 2017

Endocytosis is a process by which cells absorb extracellular materials via the inward budding of vesicles formed from the plasma membrane. Receptor-mediated endocytosis is a highly selective process where receptors with specific binding sites for extracellular molecules internalize via vesicles. G protein-coupled receptors (GPCRs) are the largest single family of plasma-membrane receptors with more than 1000 family members. But the molecular mechanisms involved in the regulation of GPCRs are believed to be highly conserved. For example, receptor phosphorylation in collaboration with ${\beta}$-arrestins plays major roles in desensitization and endocytosis of most GPCRs. Nevertheless, a number of subsequent studies showed that GPCR regulation, such as that by endocytosis, occurs through various pathways with a multitude of cellular components and processes. This review focused on i) functional interactions between homologous and heterologous pathways, ii) methodologies applied for determining receptor endocytosis, iii) experimental tools to determine specific endocytic routes, iv) roles of small guanosine triphosphate-binding proteins in GPCR endocytosis, and v) role of post-translational modification of the receptors in endocytosis.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1989.04a
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• pp.5-10
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• 1989

In this study, the basic concept of design response spectrum is briefly revi-ewed. To generate the artificial earthquake acceleration, the method of superpo-sition of cosine waves is used. Theoretical developments using F.F.T. and spect-ral density function are compared. The amplitude was derived by use of the peak factor and the phase angle is d-erived by use of Monte Carlo simulation. To smoothen the match, the calculated pseudo velocity respon-se spectrum is compared with input pseudo velocity response spectrum at a set of control frequencies. With the modified spectral density function, a new acceleration and pseudo velocity response spectrum are generat-ed.

• Publications of The Korean Astronomical Society
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• v.32 no.1
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• pp.337-341
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• 2017

This paper reviews the requirements for far-infrared astronomy in the period following the SPICA satellite in the late 2020's. We take a very long view of the state of FIR astronomy and what facilities will be required in a twenty year timeframe. We show that spatial resolution to match that of observatories operating in the optical and mid-infrared and the radio will be a necessity. Moreover this high spatial resolution must be combined with high spectral and photometric sensitivity to provide the data required to further our understanding of planetary formation mechanisms, the history of star formation through cosmic time and the feedback between active galactic nuclei and their host galaxies in controlling star formation. We review three possible conceptual mission scenarios and comment on the possibility of realising them in the coming deades.

• Journal of Plant Biology
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• v.33 no.3
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• pp.211-215
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• 1990

There is a family of homologous proteins known to small GTP-inding proteins which have a GTP binding domains and GTPase activity with molecular weight of about 20000 in mammalian tissues. Recently at least 20 different small GTP-binding proteins including three rasproto-oncogene, smg25, rho, and ral gene products were identified. These proteins play a central role in cellular prolifration, neoplasia, signal transduction, terminal differentiation, and secretory process of the cells. In this review, I have briefly compiled current information on the different areas of research in the small GTP-binding proteins in an attempt to convey an overall view of the fundamental role that this family of protein in normal cellular processes. Moreover, furture goals of research in the small GTP-binding proteins as well as the possible existence of this family of proteins in plant cells were discussed.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.11a
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• pp.79-87
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• 2002

An attempt to automate the surface finishing process of the die and mould has been carried out. An UMB(Ultrasonic Micro Burnishing) equipment which brought the micro plastic cold deformation to the 3D sculptured surface of mold and dies by ultrasonic vibration and static load, was developed and installed at the head stock of a vertical machining center. To be satisfied with the required surface roughness and hardness, the DB based program was also developed and applied. This equipment composes of UMB equipement, CNC vertical machining center, CAD/CAM system and the DB based program fer optimal condition. UMB processing effect was obtained from initial value Ral.25 and Hk337 to Ra0.085 and Hk521 and similar result was shown in industrial mould application.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1996.10a
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• pp.333-336
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• 1996

The sign language is a method of communication for deaf person. For sign communication, sign language and manual alphabet are used continuously. In this paper is proposed a system which recognize Korean sign language(KSL) and Korean manual alphabet(KMA) continuously. For recognizing KSL and KMA, basic elements for sign language, namely, the 14 hand directions, 23 hand postures, and 14 hand orientations are used. At first, this system recognize current motion state using speed and change of speed in motion by state automata. Using state, basic element classifiers using Fuzzy Min-Max Neural Network and Fuzzy Rule are executed. Meaning of signed gesture is selected by using basic elements which was recognized.