• 디자인학연구
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• 16호
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• pp.17-25
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• 1996

, \l!ernatives in multi dimensional decision prohlems generally possess numerous attrihutes by which they can be describ('d and compared, The ('\';dllation factors include all attributes that have Ic\'(']s specified by quantitative and qualitativc objectil'l'S, Howev'('f since qualitative factors arc difficul! to quantify as num('ral estimates, these factors have tended to bl' ignored without regard for their importance to human contrnl. In this study, the author adapted :j ('va]uation methods with critrria which have qualitative and qualitative attributes: the Intuitive Evaluation ~1cthods the Accumulativc' Evaluation Model the Benchmarking Evaluation Methods, and studied the corrC'iation between them, The results show that Ill(' :j Mrthods have reciprocal relationships under reliability (r=O, (XX)]] In order to removl' obstacles of desi!;n ev'aluation ( lots of timl' l'llnsumption, constr;lints of placc" difficulties of hu!;!' data procc'ssin!;), it is necessary to be developed a new ('va]uation syst('rn which could prov'idc' effective rat in!; of desi!;n v'alm's 10 make value judw'rnents, , \l!ernatives in multi dimensional decision prohlems generally possess numerous attrihutes by which they can be describ('d and compared, The ('\';dllation factors include all attributes that have Ic\'(']s specified by quantitative and qualitativc objectil'l'S, Howev'('f since qualitative factors arc difficul! to quantify as num('ral estimates, these factors have tended to bl' ignored without regard for their importance to human contrnl. In this study, the author adapted :j ('va]uation methods with critrria which have qualitative and qualitative attributes: the Intuitive Evaluation ~1cthods the Accumulativc' Evaluation Model the Benchmarking Evaluation Methods, and studied the corrC'iation between them, The results show that Ill(' :j Mrthods have reciprocal relationships under reliability (r=O, (XX)]] In order to removl' obstacles of desi!;n ev'aluation ( lots of timl' l'llnsumption, constr;lints of placc" difficulties of hu!;!' data procc'ssin!;), it is necessary to be developed a new ('va]uation syst('rn which could prov'idc' effective rat in!; of desi!;n v'alm's 10 make value judw'rnents,alm's 10 make value judw'rnents,

• 한국안광학회지
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• 제13권3호
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• pp.65-71
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• 2008

목적: 본 연구는 시중에서 유통되고 있는 완성품 돋보기와 안경원에서 조제가공된 돋보기의 광학적 중심점간의 문제점을 비교하여 눈에 미치는 영향을 연구하였다. 방법: 연구대상은 +1.00D에서 +4.00D까지 11개의 범주로 나누어 측정하였으며, 광주시 광산구에 사는 안질환이 없는 40세 이상의 남녀로 안경테 사이즈를 세 그룹으로 나누어 광학적 중심점과 광학적 높이를 측정하였다. 결과: 광학적 중심점은 57 mm에서 80 mm 범위 사이에 있었으며 대부분 61 mm에서 65 mm(64.6%) 사이였다. 광학적 중심높이 오차는 1 mm에서 8 mm 범주에 있었으며 4 mm가 공통범주(23%)에 속하였다. 완성품 돋보기는 불규칙한 사이즈를 가지고 있었다. 조사대상들은 거의 대부분 75.5%(151명)가 시중에 유통되는 완성품 돋보기를 사용하고 있었다. 대상자 151명을 조사한 결과, 완성품 돋보기의 광학적 중심점과 장용자의 P.D 사이에는 4 mm의 공통된 오차가 있었다. 더구나 광학적 중심 높이와 착용자의 O.H 사이에는 3 mm에서 4 mm의 오차가 있었다. 151명의 완성품 돋보기를 사용하는 사람들은 모두 피곤함을 느끼고 있었으며, 53명(35%)은 돋보기 착용 후 10분에서 20분 후부터 피곤함을 호소하였다. 이러한 조사를 바탕으로, 우리는 돋보기에 있어서 광학적 중심점 오차시 발생되는 프리즘 값을 발견할 수 있었으며 이는 완성품 돋보기가 착용하기에 충분하지 않다는 것을 나타낸다. 완성품 돋보기는 렌즈 굴절력과 상관관계가 있다는 것을 알 수 있었으며 또한 독일 RAL-915 규정을 따르지 않는다는 것도 알 수 있었다. 결론: 우리가 조사한 바를 기초로 할 때 완성품 돋보기는 우리의 시생활에 많은 위험적인 요소를 품고 있으며 안경사는 광학적 중심점을 토대로 정확하게 조제가공된 돋보기를 소비자에게 반드시 권하여야 할 것이다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 하계종합학술대회 논문집(4)
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• pp.89-92
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• 2001

In this paper, we propose a new approach for tracking a moving object in moving image sequences using active contour models and optical flow. In our approach object segmentation is achieved by active contours, and object tracking is done by motion estimation based on optical flow. To get more dynamic characteristics, Lagrangian dynamics combined to the active contour models. For the optical flow computation, a method, which is based on Spatiotempo-ral Energy Models, is employed to perform robust tracking under poor environments. A prototype real tracking system has been developed and applied to a contents-based video retrieval systems.

• 대한의생명과학회지
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• 제15권4호
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• pp.327-333
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• 2009

Heterotrimeric GTP binding proteins, G-proteins, mediate signal transduction generated by neurotransmitters and hormones. Among G-proteins, Go proteins are the most abundant in brain and classified as a member of Gi family. Ras-like protein in all tissues (Rit), one of the small GTPases, is a member of a Ras superfamily and identified as an important regulator of neuronal differentiation and cell transformation. Recently, we have reported that Rit functioned as a candidate downstream effector for alpha subunit of Go proteins ($Go{\alpha}$) and regulated neurite outgrowth triggered by $Go{\alpha}$ activation. In this study, we showed that the GTPase domain of $Go{\alpha}$ contributed to the direct interaction with Rit. We also demonstrated that $Go{\alpha}$ could lead to an increase of Rit activity suggesting that Rit play a role as a downstream effector of $Go{\alpha}$.

• Biomolecules & Therapeutics
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• 제25권1호
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• pp.26-43
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• 2017

Endocytosis is a process by which cells absorb extracellular materials via the inward budding of vesicles formed from the plasma membrane. Receptor-mediated endocytosis is a highly selective process where receptors with specific binding sites for extracellular molecules internalize via vesicles. G protein-coupled receptors (GPCRs) are the largest single family of plasma-membrane receptors with more than 1000 family members. But the molecular mechanisms involved in the regulation of GPCRs are believed to be highly conserved. For example, receptor phosphorylation in collaboration with ${\beta}$-arrestins plays major roles in desensitization and endocytosis of most GPCRs. Nevertheless, a number of subsequent studies showed that GPCR regulation, such as that by endocytosis, occurs through various pathways with a multitude of cellular components and processes. This review focused on i) functional interactions between homologous and heterologous pathways, ii) methodologies applied for determining receptor endocytosis, iii) experimental tools to determine specific endocytic routes, iv) roles of small guanosine triphosphate-binding proteins in GPCR endocytosis, and v) role of post-translational modification of the receptors in endocytosis.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1989년도 봄 학술발표회 논문집
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• pp.5-10
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• 1989

In this study, the basic concept of design response spectrum is briefly revi-ewed. To generate the artificial earthquake acceleration, the method of superpo-sition of cosine waves is used. Theoretical developments using F.F.T. and spect-ral density function are compared. The amplitude was derived by use of the peak factor and the phase angle is d-erived by use of Monte Carlo simulation. To smoothen the match, the calculated pseudo velocity respon-se spectrum is compared with input pseudo velocity response spectrum at a set of control frequencies. With the modified spectral density function, a new acceleration and pseudo velocity response spectrum are generat-ed.

• 천문학논총
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• 제32권1호
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• pp.337-341
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• 2017

This paper reviews the requirements for far-infrared astronomy in the period following the SPICA satellite in the late 2020's. We take a very long view of the state of FIR astronomy and what facilities will be required in a twenty year timeframe. We show that spatial resolution to match that of observatories operating in the optical and mid-infrared and the radio will be a necessity. Moreover this high spatial resolution must be combined with high spectral and photometric sensitivity to provide the data required to further our understanding of planetary formation mechanisms, the history of star formation through cosmic time and the feedback between active galactic nuclei and their host galaxies in controlling star formation. We review three possible conceptual mission scenarios and comment on the possibility of realising them in the coming deades.

• Journal of Plant Biology
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• 제33권3호
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• pp.211-215
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• 1990

There is a family of homologous proteins known to small GTP-inding proteins which have a GTP binding domains and GTPase activity with molecular weight of about 20000 in mammalian tissues. Recently at least 20 different small GTP-binding proteins including three rasproto-oncogene, smg25, rho, and ral gene products were identified. These proteins play a central role in cellular prolifration, neoplasia, signal transduction, terminal differentiation, and secretory process of the cells. In this review, I have briefly compiled current information on the different areas of research in the small GTP-binding proteins in an attempt to convey an overall view of the fundamental role that this family of protein in normal cellular processes. Moreover, furture goals of research in the small GTP-binding proteins as well as the possible existence of this family of proteins in plant cells were discussed.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2002년도 제5회 압출 및 인발가공 심포지엄
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• pp.79-87
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• 2002

An attempt to automate the surface finishing process of the die and mould has been carried out. An UMB(Ultrasonic Micro Burnishing) equipment which brought the micro plastic cold deformation to the 3D sculptured surface of mold and dies by ultrasonic vibration and static load, was developed and installed at the head stock of a vertical machining center. To be satisfied with the required surface roughness and hardness, the DB based program was also developed and applied. This equipment composes of UMB equipement, CNC vertical machining center, CAD/CAM system and the DB based program fer optimal condition. UMB processing effect was obtained from initial value Ral.25 and Hk337 to Ra0.085 and Hk521 and similar result was shown in industrial mould application.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1996년도 추계학술대회 학술발표 논문집
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• pp.333-336
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• 1996

The sign language is a method of communication for deaf person. For sign communication, sign language and manual alphabet are used continuously. In this paper is proposed a system which recognize Korean sign language(KSL) and Korean manual alphabet(KMA) continuously. For recognizing KSL and KMA, basic elements for sign language, namely, the 14 hand directions, 23 hand postures, and 14 hand orientations are used. At first, this system recognize current motion state using speed and change of speed in motion by state automata. Using state, basic element classifiers using Fuzzy Min-Max Neural Network and Fuzzy Rule are executed. Meaning of signed gesture is selected by using basic elements which was recognized.