• 생명과학회지
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• 제22권2호
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• pp.156-160
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• 2012

수증기증류법으로 얻은 제주산 배초향의 정유는 DPPH radical 소거활성이 현저하게 뛰어나는 것을 확인할 수가 있었다. 제주산 배초향의 유효성분을 확인하기 위해 정유성분을 GC-MS로 분석한 결과 각 성분의 retention time및 mass spectral data의 표준 물질과의 비교에 의해서 Pulegone, L-menthone, DL-limonene, Isopulegone, beta-caryophyllene, beta-myrcene, estragole. 등의 정유성분이 확인되었다. 이 연구에서 밝혀진 여러 성분들은 천연유기합성물로 항산화 활성이 잘 알려져 있어 이들이 그 유효성분으로 추측된다. 연구결과 제주산 배초향 정유는 식품 보존제 및 항산화 대체 물질로 개발이 적합하다.

• 대한의생명과학회지
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• 제23권4호
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• pp.355-361
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• 2017

In this study, antioxidant and anti-inflammatory of fermented Houttuynia cordata Thunb and scoria mixture extract were investigated in vitro. Radical-scavenging activities of the ethanol extracts were examined by using ${\alpha},{\alpha}$-diphenyl-${\beta}$-picrylhydrazyl (DPPH) and 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS)) radicals assay. Consequently, we confirmed that fermented Houttuynia cordata Thunb and scoria mixture extract dependent removed DPPH and ABTS radical. Also, to confirm anti-inflammatory activity of ethanol extract, we treated fermented Houttuynia cordata Thunb and scoria mixture extract on BV-2 cell with LPS. The result showed that fermented Houttuynia cordata Thunb and scoria mixture extract concentration-dependent inhibited NO production. Therefore, fermented Houttuynia cordata Thunb and scoria mixture extract showed inhibition radical oxygen activities and inflammatory and have available for a pharmacological composition on neuritis-protection and treatment.

• BMB Reports
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• 제29권5호
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• pp.423-428
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• 1996

A superoxide anion radical scavenger isolated from Capsella bursa-pastoris was characterized by infrared (IR) spectroscopy, sugar analysis, ultraviolet (UV) spectroscopy, $^{1}H$ and $^{13}C$ nuclear magnetic resonance (NMR) spectroscopies, and fast atom bombardment (FAB) mass analysis. The compound was assumed to be a flavonoid-O-glycoside from IR spectrum and UV absorption maxima. When the sugar composition of the compound was examined by thin layer chromatography (TLC) and gas chromatography (GC) of the acid hydrolysate, only glucose was detected. According to the results of UV spectrotroscopy by using shift reagents, the compound was supposed to be luteolin (5,7,3',4'-tetrahydroxy flavone) or chrysoeriol (5,7,4'-trihydroxy-3'-methoxy flavone) with glucose. Based on $^{1}H$- and $^{13}C-NMR$ spectroscopies, the compound was deduced as 7,4'-dihydroxy-5,3'-dimethoxy-${\alpha}$-6-c-glucosyl-${\beta}$-2"-o-glucosyl flavone. In FAB mass analysis the compound was finally characterized as 7,4'-dihydroxy-5,3'-dimethoxy-${\alpha}$-6-c-glucosyl-${\beta}$-2"-o-glucosyl flavone ($C_{29}H_{34}O_{16}$, M.W.=638).

• 대한수학회지
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• 제42권3호
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• pp.457-470
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• 2005

Yu showed that every right (left) primitive factor ring of weakly right (left) duo rings is a division ring. It is not difficult to show that each weakly right (left) duo ring is abelian and has the classical right (left) quotient ring. In this note we first provide a left duo ring (but not weakly right duo) in spite of it being left Noetherian and local. Thus we observe conditions under which weakly one-sided duo rings may be two-sided. We prove that a weakly one-sided duo ring R is weakly duo under each of the following conditions: (1) R is semilocal with nil Jacobson radical; (2) R is locally finite. Based on the preceding case (1) we study a kind of composition length of a right or left Artinian weakly duo ring R, obtaining that i(R) is finite and $\alpha^{i(R)}R\;=\;R\alpha^{i(R)\;=\;R\alpha^{i(R)}R\;for\;all\;\alpha\;{\in}\;R$, where i(R) is the index (of nilpotency) of R. Note that one-sided Artinian rings and locally finite rings are strongly $\pi-regular$. Thus we also observe connections between strongly $\pi-regular$ weakly right duo rings and related rings, constructing available examples.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제25권2호
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• pp.17-25
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• 2019

Purpose: The analysis of spatial composition is required for the creation of healing environment in healthcare facilities. This study has been accomplished to provide basic data for the planning and design of hospital architecture. Methods: Literature review of healing environment and investigation on characteristics of spatial composition in healthcare facilities have been conducted. The architectural plans of four Sou Fujimoto's healthcare projects have been analyzed with space syntax. Results: The result of this research can be summarized as followed. First of all, the healing environments are consisted with architectural composition in addition to physical and psychological factors for healing environment. The second one is that the characteristics of spatial composition in Sou Fujimoto's healthcare projects are different private/public/corridor relationships in program configuration, loop or one direction circulation, combined or independent corridor with program, and radical or linear connection in spatial connection methods. The third one is that the characteristics of spatial composition in selected cases through space syntax are high variation on integration, low variation on connectivity, and high distribution in main circulation on ERAM(3). Implications: In addition to the specific spatial composition in healthcare facilities of the architect's project, it is necessary to analyze the relationship with other factors and facilities to develop the planning of hospital architecture.

• 한국수소및신에너지학회논문집
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• 제27권2호
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• pp.220-229
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• 2016

A numerical study on lifted flame structure in impinging jet geometry with syngas composition ratio was investigated. The numerical calculations including chemical kinetic analysis were conducted using SPIN application of the CHEMKIN Package with Davis-Mechanism. The flame temperature and velocity profiles were calculated at the steady state for one-dimensional stagnation flow geometry. Syngas mixture compositions were adjusted such as $H_2:CO=10:90(10P)$, 20 : 80 (20P), 30 : 70 (30P), 40 : 60 (40P), 50 : 50 (50P). As composition ratios are changed from 10P to 50P, the axial velocity and flame temperature increase because the contents of hydrogen that have faster burning velocity increase. This phenomenon is due to increase in good reactive radicals such as H, OH radical. As a result of active reactivity, the burning velocity is more faster and this is confirmed by numerical methods. Consequently, combustion reaction zone was moved to burner nozzle.

• Genomics & Informatics
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• 제8권4호
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• pp.170-176
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• 2010

The Ribonucleotide reductases (RNR) are essential enzymes that catalyze the conversion of nucleotides to deoxynucleotides in DNA replication and repair in all living organisms. The RNRs operate by a free radical mechanism but differ in the composition of subunit, cofactor required and regulation by allostery. Based on these differences the RNRs are classified into three classesclass I, class II and class III which depend on oxygen, adenosylcobalamin and S-adenosylmethionine with an iron sulfur cluster respectively for radical generation. In this article thirty seven sequences belonging to each of the three classes of RNR were analyzed by using various tools of bioinformatics. Phylogenetic analysis, dot-plot comparisons and motif analysis was done to identify a number of differences in the three classes of RNRs. In this research article, we have attempted to decipher evolutionary relationship between the three classes of RNR by using bioinformatics approach.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.324-324
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• 2006

In copolymerization of methyl acrylate (MA) and methyl methacrylate (MMA) with various ratios of MA to MMA and $[CuCl]/[PMDETA]/[PVAc-CCl_{3}]$ catalyst system in bulk at $80^{\circ}C$ via ATRP, several terpolymer with different copolymer composition, were synthesized. The atom transfer radical copolymerization of MA and MMA with macroinitiator, is very sensitive to molecular weight and its distribution. In this work it was possible to calculate the molecular weight of the terpolymers and show that it is close to the experimentally determined number average molecular weight from GPC.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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• pp.207-212
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• 1994

A mathematical model is developed for a batch reactor in which the free radical bulk copolymerization of styrene and acrylonitrile takes place. In this model, we introduce the free volume theory to quantify the diffusion controlled termination and propagation reactions, and develop a model for the chain length dependent termination reaction in the context of the pseudo kinetic rate constant method(PKRCM). The simulation results from this model are found to be in good agreement with experimental data under different copolymerization conditions. The present model can predict both the copolymer composition and the number and weight average molecular weights. These kinetic approaches provide greater insight into the performance of the batch reactor used for the free radical bulk copolymerization of styrene and acrylonitirle.

• Preventive Nutrition and Food Science
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• 제21권4호
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• pp.338-347
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• 2016

The present study investigated the volatile compound, physicochemical, and antioxidant properties of beany flavor-removed soy protein isolate (SPI) hydrolyzates produced by combined high temperature pre-treatment and enzymatic hydrolysis. Without remarkable changes in amino acid composition, reductions of residual lipoxygenase activity and beany flavor-causing volatile compounds such as hexanol, hexanal, and pentanol in SPI were observed after combined heating and enzymatic treatments. The degree of hydrolysis, emulsion capacity and stability, 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity, and superoxide radical scavenging activity of SPI were significantly increased, but the magnitudes of apparent viscosity, consistency index, and dynamic moduli (G', G") of SPI were significantly decreased after the combined heating and enzymatic treatments. Based on these results, it was suggested that the enzymatic hydrolysis in combination with high temperature pre-treatment may allow for the production of beany flavor-removed SPI hydrolyzates with superior emulsifying and antioxidant functionalities.