• 대한방사선기술학회지:방사선기술과학
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• 제34권2호
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• pp.149-156
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• 2011

본 연구는 컴퓨터 단층촬영(Computed Tomography; 이하 CT)검사 환자를 대상으로 요인별 불안에 따른 지각과 반응의 정도를 파악하고, 변수들 간의 관련성을 분석하여 CT검사 환자의 검사에 대한 인식을 향상시켜 불안을 감소시키기 위한 과학적 기초자료를 제공하고자 실시하였다. 연구 대상은 2010년 7월부터 2010년 9월까지 3개의 대학병원 영상의학과에서 CT검사 환자 263명을 대상으로 구조화된 자기기입식으로 설문조사 를 실시하였다. CT 검사 대상자의 불안에 대한 영향을 알아보기 위해 단변량 분석으로 독립변수의 CT검사 관련 특성에 따른 CT검사 요인별 불안은 환자의 방사선 노출, CT검사 이유, 질병상태 인지여부, 비용 부담자, 경제적 부담, 충분한 설명, 설명 주체에 따른, 내시경 조직검사 유무, 사전 처치에 따른, CT검사 이전에 따른, CT부작용 경험에 따른, 조영제 부작용에 발생에 따른 요인으로 나뉘어지고 종속변수의 불안 요인은 신체적 요인, 병원종사자 요인, 병원환경 요인, 사회경제적 요인으로 나뉘어 SPSS WIN(ver. 13.0) 통계프로그램을 이용하여 분석하였다. 이상의 연구 결과를 종합해 볼 때, CT검사 환자의 요인별 불안의 지각과 반응의 정도가 경제부담, 상태불안, 전처치 불안, 방사선 노출 불안, 부작용 불안에서 유의한 차이를 보여주고 있다. 따라서 검사의 전처치와 조영제의 화학적 독성, 부작용에 관한 사전교육프로그램 개발을 통해 CT검사 환자들의 검사에 대한 불안을 감소시킬 수 있을 것으로 사료되며 이러한 연구를 기초 자료로 CT검사 환자의 불안정도와 불안요인을 감소시키기 위해서 중재 방안이 지속적으로 연구되고 개선되어야 할 것이다. 또한 환자의 경제적 부담이 CT검사 불안에 영향을 미치는 것을 인지하고 사회적으로 해결해 나가야 할 것이라 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10193-10198
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• 2015

Background: Cancer is a major cause of mortality in developing countries and correct and valid information about the epidemiology of this disease is the first step in the planning of health care in each region. The aim of this study was to determine the relative frequency, mean age and sex ratio of the most 10 common non-skin cancers in the world and Iran, among patients referred to an oncology clinic. Materials and Methods: This descriptive study was conducted in Mashhad, north east of Iran. The data obtained from the records of patients referred to the private oncology center between the years of 1985-2012". According to the latest report of GLOBOCAN study commonest malignancies included were lung, breast, colorectal, prostate, stomach, liver, cervix, esophageal, bladder cancers and Non-Hodgkin lymphoma. Results: A total of 4,606 cases were analyzed. The mean age was $55.5{\pm}13.8years$ (male: $59.5{\pm}13.9$, female: $52.6{\pm}12.9$). Overall, breast cancer (1,264 cases, relative frequency of 27.4%) was the most prevalent cancer; however the mean ages of diagnosis were not significantly different between 5-year time period divisions (p=0.290). The most common cancer in men was esophageal cancer (26.3%).The lowest mean age was related to women diagnosed with breast cancer ($48.5{\pm}11.8$) and men with non-Hodgkins lymphoma ($48.4{\pm}17.8$). There were statistically significant differences between the mean age of men and women with gastric (p=0.003) and esophageal cancers (p<0.001). Male to female sex ratios in our study for bladder, lung and stomach cancers were 6.57, 2.60 and 2.50 respectively. Conclusions: The results showed that breast cancer tends to be found in younger female patients and bladder cancer appears more often in men. Screening in target population in addition to early diagnosis may reduce death and disability.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.141-141
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• 2017

The ubiquitin-proteasome pathway is the major regulatory mechanism in a number of cellular processes for selective degradation of proteins and involves three steps: (1) ATP dependent activation of ubiquitin by E1 enzyme, (2) transfer of activated ubiquitin to E2 and (3) transfer of ubiquitin to the protein to be degraded by E3 complex. F-box proteins are subunit of SCF complex and involved in specificity for a target substrate to be degraded. F-box proteins regulate many important biological processes such as embryogenesis, floral development, plant growth and development, biotic and abiotic stress, hormonal responses and senescence. However, little is known about the F-box genes in wheat. The draft genome sequence of wheat (IWGSC Reference Sequence v1.0 assembly) used to analysis a genome-wide survey of the F-box gene family in wheat. The Hidden Markov Model (HMM) profiles of F-box (PF00646), F-box-like (PF12937), F-box-like 2 (PF13013), FBA (PF04300), FBA_1 (PF07734), FBA_2 (PF07735), FBA_3 (PF08268) and FBD (PF08387) domains were downloaded from Pfam database were searched against IWGSC Reference Sequence v1.0 assembly. RNA-seq paired-end libraries from different stages of wheat, such as stages of seedling, tillering, booting, day after flowering (DAF) 1, DAF 10, DAF 20, and DAF 30 were conducted and sequenced by Illumina HiSeq2000 for expression analysis of F-box protein genes. Basic analysis including Hisat, HTseq, DEseq, gene ontology analysis and KEGG mapping were conducted for differentially expressed gene analysis and their annotation mappings of DEGs from various stages. About 950 F-box domain proteins identified by Pfam were mapped to wheat reference genome sequence by blastX (e-value < 0.05). Among them, more than 140 putative F-box protein genes were selected by fold changes cut-offs of > 2, significance p-value < 0.01, and FDR<0.01. Expression profiling of selected F-box protein genes were shown by heatmap analysis, and average linkage and squared Euclidean distance of putative 144 F-box protein genes by expression patterns were calculated for clustering analysis. This work may provide valuable and basic information for further investigation of protein degradation mechanism by ubiquitin proteasome system using F-box proteins during wheat development stages.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4429-4434
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• 2015

Background: Public awareness/knowledge on oral and pharyngeal cancer (OPC), potentially malignant disorders (PMODs) and their risk factors is crucial for prevention and early detection of OPC and PMODs. Yet, there are no published data available on the awareness and knowledge of OPC and PMODs among people living in Far North Queensland, Australia. Materials and Methods: This study was conducted as a cross sectional survey. A self-administered questionnaire was designed and consisted of relevant questions to ascertain socio-demographic information, awareness and knowledge of OPC, PMODs and risk factors and questions on participant's exposure to risk factors and dietary history were also included. Survey was carried out at the Dental Clinic of the James Cook University School of Dentistry (JCU Dental), Cairns, Australia. Subjects above the age of 20 years (n=366) were randomly selected during the period from 31st July to 6th September 2013 and questionnaire was distributed to complete while they are waiting for treatment. Data analysis was carried out using SPSS version 21 and the chi -squared test was employed to compare groups. P<0.05 was considered statistically significant. Results: The study revealed that 52.3% of the respondents were aware of the existence of OPC but only 19.0% were aware of PMODs. Of those who were aware of oral cancer, 92% agreed or strongly agreed that smoking is a strong risk factor for OPC. Similarly a relatively high proportion of the respondents agreed or strongly agreed that tobacco chewing (84%), tobacco chewing with areca nut (68%), chewing areca nut alone (51%) and exposure to actinic radiation (71%) as risk factors. However, the results for alcohol intake, age, and HPV infection were found to be relatively poor with proportions 33%, 34%, and 23% respectively. Conclusions: This study revealed an alarming lack of awareness and knowledge of OPC and PMODs.

• Journal of Hospice and Palliative Care
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• 제20권1호
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• pp.18-25
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• 2017

목적: 돌발성 통증을 적절히 조절하는 것은 암환자에서 필수적이다. 돌발성 통증을 조절하는 것은 의료진이 돌발성 통증에 대해 잘 이해하고 적절한 구제 진통제를 사용하는 것에 달려있다. 본 연구는 한국 완화의료 전문의들의 돌발성 통증에 대한 견해와 진료 형태에 대해 알아보고자 하였다. 방법: 본 연구는 한국호스피스 완화의료학회에서 시행된 2014년 돌발성 통증 설문조사를 바탕으로 진행하였다. 100명의 의사가 온라인 설문조사에 참여하였다. 총 33개의 자가 기입식 설문 문항 중에서 12개의 항목이 분석에 사용되었다. 결과: 빠른 작용 발현은 구제 진통제를 선택함에 있어 가장 중요한 요소였다. 경구 옥시코돈(65%)과 모르핀 주사제(27%)는 흔히 사용되는 구제진통제였다. 소수의 의사들(3%)만이 점막 흡수형 펜타닐을 선호하였다. 빠른 작용 발현 때문에 경구 옥시코돈을 선택한다고 답변한 의사들은 21.5%였으며, 반면에 빠른 작용 발현 때문에 모르핀 주사제를 처방한 의사들은 81.5%였다. 전체 응답자의 약 66%는 돌발성 통증이 구제 진통제로 잘 조절되지 않는다고 답변했다. 결론: 돌발성 통증 조절에 의료진들은 어려움을 느끼고 있었고, 의료진들이 구제진통제를 선택함에 있어서 필요로 하는 중요한 요소와 실제 처방의 형태에는 차이가 있었다.

• 대한방사선기술학회지:방사선기술과학
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• 제18권2호
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• pp.87-102
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• 1995

The education of radiologic technology began in the regular institute of higher education in Korea in 1963. Up to now from then, our education to bring up the radiologic technologists has developed greatly in quality and quantity, and now departments of radio-technology are founded in the 16 junior colleges in March, 1995. This study was done to verify the necessity and propriety to reform the education system of radiologic technology which was run as two or three year system of college curriculum for 32 years since 1963, and to search for the method to reform in the future. We got the following results from this research. 1. In the survey, on the desirable education year for radiologic technologists, 63.9 % of professors of department of radio-technology and 63.0 % of radiologic technologists chose the 4 year system, 27.9 % of professors and 34.6 % of radiologic technologists chose the 4 year system added to graduate school. 2. In the survey, on the future development of radiologic equipments and technique, 67.2 % of professors of department of radiologic technology and 86.4 % of radiologic technologists have a view of "revolutional development". Also, on the future tasks or roles of radiologic technologists 95.1% of professors and 94.9% of radiologic technologists have a view that "They will increase". 3. On the necessity of extension of education year to 4 years from 3 years, the factor is that development of medical technique and machinery and tools, advance of qualification of radiologic technologists, enlargement and specialization of the business of the radiologic technologists, ballance of education year with other medical sciences, international competitive power and cooperation of radiologic technology, and education continuation of the graduates of department of radiologic technology. 4. They suggested that in the 4 year curriculum of department of radiologic technology, clinical medicine, quality control of radiation and radiologic equipment, related subjects to the radiologic application and computer application should be enforced and clinical practice should be extended more. 5. On the device to found the 4 year college curriculum of radiologic technology, they suggested that first, 4 year curriculum should be founded through the variety of educational year, secondly, department of radiologic technology should be founded in the 4 year health sciences college, thirdly, educational continuation of the radiologic technologists should be systematized on the basis of life-long education.

• 한국환경생태학회지
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• 제29권6호
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• pp.907-916
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• 2015

본 연구에서는 인공조림된 편백림을 대상으로 식생구조 및 식생천이, 종다양성의 특성을 밝히고자 전남지역의 8곳에 편백림을 대상으로 식생조사를 실시하였다. 이 식생조사 데이터를 활용하여 군집분석 및 서열분석을 실시한 결과 5개 군락으로 단순화되었다. 군락I은 다른 군락에 비해 종다양성지수가 상당히 낮았는데 이는 교목층에 우점한 편백의 수관이 울폐되어 하층식생이 발달하지 않았거나 잡초목(경쟁 자생수종) 제거로 하층식생이 거의 남아있지 않았기 때문이었다. 반면, 군락 II~IV는 하층에 다양한 자생수종이 유입되어 아교목층과 관목층에서 서로 경쟁하여 어느 정도 안정되거나 식생발달 초기라서 종다양성지수가 높은 편이었다. 마지막, 군락 V는 휴양림으로서 이용강도가 높아 식생구조가 단순하였다. 또한, 임상에 유입되는 광합성유효광과 출현종수 종다양성지수 사이에는 정의 상관관계를 보였다. 이러한 편백림의 식생구조 특성은 과거 개벌 이후 묘목심기, 솎아베기, 풀베기 등의 산림시업과 밀접하게 관련된다. 편백림의 산림시업에 의한 교란빈도와 함께 식생천이프로세스 회전시간에 따라 군락별 식생구조와 종다양성은 약간의 차이를 보였지만, 천연림에 비해 편백림은 단순한 식생구조를 보였다. 인공림은 생물다양성이 낮고 생태계 서비스가 취약하기 때문에 공익적 기능을 발휘할 수 있는 인공림으로 전환하는 한 가지 수단으로써 생태적 관리가 필요할 것이다.

• 천문학회보
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• 제38권1호
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• pp.36.2-36.2
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• 2013

The SPICA (SPace Infrared Telescope for Cosmology & Astrophysics) project is a next-generation infrared space telescope optimized for mid- and far-infrared observation with a cryogenically cooled 3m-class telescope. The focal plane instruments onboard SPICA will enable us to resolve many astronomical key issues from the formation and evolution of galaxies to the planetary formation. The FPC-S (Focal Plane Camera - Sciecne) is a near-infrared instrument proposed by Korea as an international collaboration. Owing to the capability of both low-resolution imaging spectroscopy and wide-band imaging with a field of view of $5^{\prime}{\times}5^{\prime}$, it has large throughput as well as high sensitivity for diffuse light compared with JWST. In order to strengthen advantages of the FPC-S, we propose the studies of probing population III stars by the measurement of cosmic near-infrared background radiation and the star formation history at high redshift by the discoveries of active star-forming galaxies. In addition to the major scientific targets, to survey large area opens a new parameter space to investigate the deep Universe. The good survey capability in the parallel imaging mode allows us to study the rare, bright objects such as quasars, bright star-forming galaxies in the early Universe as a way to understand the formation of the first objects in the Universe, and ultra-cool brown dwarfs. Observations in the warm mission will give us a unique chance to detect high-z supernovae, ices in young stellar objects (YSOs) even with low mass, the $3.3{\mu}$ feature of shocked circumstance in supernova remnants. Here, we report the current status of SPICA/FPC project and its extragalactic sciences.

• 한국환경복원기술학회지
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• 제22권5호
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• pp.1-12
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• 2019

It is important to measure the height of trees as an essential element for assessing the forest health in urban areas. Therefore, an automated method that can measure the height of individual tree as a three-dimensional forest information is needed in an extensive and dense forest. Since airborne LiDAR dataset is easy to analyze the tree height(z-coordinate) of forests, studies on individual tree height measurement could be performed as an assessment forest health. Especially in urban forests, that adversely affected by habitat fragmentation and isolation. So this study was analyzed to measure the height of individual trees for assessing the urban forests health, Furthermore to identify environmental factors that affect forest growth. The survey was conducted in the Mt. Bongseo located in Seobuk-gu. Cheonan-si(Middle Chungcheong Province). We segment the individual trees on coniferous by automatic method using the airborne LiDAR dataset of the two periods (year of 2016 and 2017) and to find out individual tree growth. Segmentation of individual trees was performed by using the watershed algorithm and the local maximum, and the tree growth was determined by the difference of the tree height according to the two periods. After we clarify the relationship between the environmental factors affecting the tree growth. The tree growth of Mt. Bongseo was about 20cm for a year, and it was analyzed to be lower than 23.9cm/year of the growth of the dominant species, Pinus rigida. This may have an adverse effect on the growth of isolated urban forests. It also determined different trees growth according to age, diameter and density class in the stock map, effective soil depth and drainage grade in the soil map. There was a statistically significant positive correlation between the distance to the road and the solar radiation as an environmental factor affecting the tree growth. Since there is less correlation, it is necessary to determine other influencing factors affecting tree growth in urban forests besides anthropogenic influences. This study is the first data for the analysis of segmentation and the growth of the individual tree, and it can be used as a scientific data of the urban forest health assessment and management.

• 한국항해항만학회지
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• 제47권3호
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• pp.174-181
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• 2023

일본 도쿄전력의 후쿠시마 원전 오염수 해양방류에 대해 한일해엽 연안 5개 지자체(제주, 전남, 경남, 부산, 울산)는 합동 대책위원회를 운영하고 있다. 본 연구는 제주연구원, 부산연구원, 울산연구원에서 일본 후쿠시마 원전 오염수 해양방류에 따른 대응 방안 연구의 일환으로 수행한 시민 설문조사, 대응 전략, 세부실천과제 등을 비교 분석하여 향후 타 연안도시 정책 입안자들이 실효성 있는 방안 마련을 위한 기초자료를 제시하는데 목적이 있다. 인식조사 결과 모든 지자체 시민들은 과학적 연구결과에 상관없이 해양방류에 대해 부정적 인식이 강한 것으로 나타나 향후 수산업, 관광업계의 피해가 클 것으로 예상된다. 지자체별 대응전략에서는 모든 지자체 공통으로 컨트롤 타워 구축이 가장 시급한 과제로 나타났다. 이는 실효성 있는 대응을 위해 공무원 조직 한계인 직제 중심에서 탈피하여 기능 중심 대응이 필요하기 때문이라고 판단된다. 또한 대응방법에 있어 제주와 부산은 분야별 대응방안을 수립한 반면, 울산시는 방류시점에 따른 단계별 대응방안으로 실질적 대응에 초점을 맞추고 있다. 내용적으로는 수산물 방사능 검사체계 구축, 국민의 불안감 해소를 위한 홍보가 중요한 것으로 나타났다. 향후 2030년까지 지속적으로 후쿠시마 원전 오염수의 해양방류가 예정되어 있는 만큼 지자체 연구기관 간 연구결과 및 성과 공유를 위한 네트워크강화가 필요할 것으로 판단된다.