• 제목/요약/키워드: Radiation resistance

검색결과 425건 처리시간 0.024초

DNA Repair Activity of Human rpS3 is Operative to Genotoxic Damage in Bacteria

  • JANG CHANG-YOUNG;LEE JAE YUNG;KIM JOON
    • Journal of Microbiology and Biotechnology
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    • 제15권3호
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    • pp.484-490
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    • 2005
  • Human ribosomal protein S3 (rpS3), which has a DNA repair endonuclease activity, is a multifunctional protein. This protein is involved in DNA repair, translation, and apoptosis. In particular, rpS3 has a lyase activity, which cleaves the phosphodiester bond of damaged sites such as cyclobutane pyrimidine dimers and AP sites. Here, using deletion analysis, we identified that the repair endonuclease domain resides in the C-terminal region (165-243 aa) of rpS3. We also found that ectopic expression of GST-rpS3 in bacterial strain BL21 promoted the resistance of these cells to ultraviolet (UV) radiation and hydrogen peroxide ($H_{2}O_{2}$) treatment. The repair domain of rpS3 was sufficient to exhibit the resistance to UV irradiation and recover cell growth and viability, showing that the repair activity of rpS3 is responsible for the resistance to UV irradiation. Our study suggests that rpS3 is able to process DNA damage in bacteria via its repair domain, showing the resistance to genotoxic stress. This implies that rpS3-like activity could be operative in bacteria.

파랑중에서 전진하는 선박의 부가저항 해석 (Analysis of added resistance of a ship advancing in waves)

  • 이호영;곽영기
    • 한국해양공학회지
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    • 제11권2호
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    • pp.91-99
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    • 1997
  • This paper presents theoretical formulations and numerical computations for predicting first-and second-order hydrodynamic force on a ship advvancing in waves. The theoretical formulation leads to linearized radiation and diffration problems solving the three-dimensional Green function integral equations over the mean wetted body surface. Green function representing a translating and pulsating source potantial for infinite water depth is used. In order to solve integral equations for three dimentional flows using Green function efficiently, the Hoff's method is adopted for numerical calculation of the Green function. Based on the first-order solution, the mean seconder-order forces and moments are obtained by directly integrating second-order pressure over the mean wetted body surface. The calculated items are carried out for analyzing the seakeeping characteristics of Series 60. The calculated items are hydrodynamic coefficients, wave exciting forces, frequency response functions and addd resistance in waves.

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옥외용 고분자 절연재료의 자외선 열화특성 연구 (A Study on the Ultraviolet Aging characteristics of Outdoor Polymeric Insulating Materials)

  • 김영성;이상진;박완기;정순욱
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1998년도 하계학술대회 논문집 D
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    • pp.1404-1406
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    • 1998
  • The outdoor polymeric insulating materials such as silicone rubber, ethylene propylene diene monomer(EPDM), ethylene vinyl acetate(EVA) and epoxy are aged by various natural environment with the long-term performance in outdoor. In this paper, the effects of UV-ray on surface of silicone rubber were investigated by using the weather-Ometer. The accelerated aging stresses were simulated by UV radiation. high temperature and humidity as well as water spray. These the aging characteristics were examined through contact angle measurements, tracking resistance test, FT-IR and SEM/EDS analysis. the experimental results showed that tracking resistance decreases with increase in the UV-ray irradiation period. But the surface of silicone rubber kept hydrophobicity. It is found that the inorganic filler such as $Al(OH)_3$ improves tracking resistance and the $TiO_2$ is very effective in preventing degradation of silicone rubber surface from UV-ray.

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Electron Beam Modification of Dual Phase Filler: Surface Characteristics and its Influence on the Properties of Styrene-Butadiene Rubber Vulcanizates

  • Shanmugharaj A. M.
    • 고무기술
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    • 제5권2호
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    • pp.94-103
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    • 2004
  • The present work describes modification of dual phase filler by electron beam irradiation in presence of multifunctional acrylates like trimethylol propane triacrylate (TMPTA) or silane coupling agent like bis (3-triethoxysilylpropyltetrasulphide) and in-fluence of the modified fillers on the physical properties of styrene-butadiene rubber (SBR) vulcanizates. Modulus at 300 % elongation increases whereas the tensile strength decreases with increase in radiation dose for the dual phase filler loaded styrene-butadiene rubber vulcanizates (SBR). However, modulus and tensile strength significantly increase, which is more, pronounced at higher filler loadings for TMPTA modified dual phase filler loaded SBR. These changes in properties are explained by the equilibrium swelling data and Kraus plot interpreting the polymer-filler interaction. Electron beam modification of the filler results in a reduction of tan ${\delta}$ at $70^{\circ}C$, a parameter for rolling resistance and increase in tan ${\delta}$ at $0^{\circ}C$, a parameter for wet skid resistance of the SBR vulcanizates. Finally, the influence of modified fillers on the properties like abrasion resistance, tear strength and fatigue failure and the improvement in the properties have been explained in terms of polymer-filler interaction.

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High alloyed new stainless steel shielding material for gamma and fast neutron radiation

  • Aygun, Bunyamin
    • Nuclear Engineering and Technology
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    • 제52권3호
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    • pp.647-653
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    • 2020
  • Stainless steel is used commonly in nuclear applications for shielding radiation, so in this study, three different types of new stainless steel samples were designed and developed. New stainless steel compound ratios were determined by using Monte Carlo Simulation program Geant 4 code. In the sample production, iron (Fe), nickel (Ni), chromium (Cr), silicium (Si), sulphur (S), carbon (C), molybdenum (Mo), manganese (Mn), wolfram (W), rhenium (Re), titanium (Ti) and vanadium (V), powder materials were used with powder metallurgy method. Total macroscopic cross sections, mean free path and transmission number were calculated for the fast neutron radiation shielding by using (Geant 4) code. In addition to neutron shielding, the gamma absorption parameters such as mass attenuation coefficients (MACs) and half value layer (HVL) were calculated using Win-XCOM software. Sulfuric acid abrasion and compressive strength tests were carried out and all samples showed good resistance to acid wear and pressure force. The neutron equivalent dose was measured using an average 4.5 MeV energy fast neutron source. Results were compared to 316LN type stainless steel, which commonly used in shielding radiation. New stainless steel samples were found to absorb neutron better than 316LN stainless steel at both low and high temperatures.

방사선 중합에 의한 폴리프로필렌 정밀여과막의 제조 및 친수화 거동에 관한 연구 (A Study on the Preparation and Hydrophilization of Polypropylene Microfiltration Membrane by Radiation-Induced Graft Polymerization)

  • 황택성;이선아;황의환
    • 폴리머
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    • 제24권5호
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    • pp.621-628
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    • 2000
  • 폴리프로필렌 다공성 분리막은 산, 알칼리에 대한 내화학성이 좋고, 기계적 성질이 우수하며 높은 열적 안정성을 가지고 있으나, 막의 소수성 때문에 일부 영역에만 사용이 제한되고 있다. 따라서 본 연구에서는 소수성 막의 성능을 향상시키기 위해서 방사선 조사에 의한 그라프트 중합법을 사용하여, 친수성 작용기 (-COOH, -OH)를 갖는 acrylic acid (AAc)와 2-hydroxyethyl methacrylate (MEMA)를 도입하였다. 이때 반응시간, 반응온도, 조사량, 간의 첨가 효과, 팽윤현상에 의한 그라프트율의 변화를 조사하였다. 분리막의 기공크기를 분석하는 방법으로 행한 가스투과 실험에서 단량체의 종류와 관계없이 그라프트가 증가함에 따라 가스 투과속도가 감소함을 보였고, 오일 에멀젼 투과실험에서 미개질 폴리프로필렌 막의 오염현상은 크게 발생하였으나, 그라프트 중합 후, 높은 투과속도를 유지하여 막의 친수화 효과가 큰 것으로 나타났다.

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800nm급 펨토초 레이저로 제작된 FBG 센서의 내방사선 특성 (Radiation resistant Characteristics of Fiber Bragg Grating Sensors made with 800-nm femtosecond laser)

  • 김종열;이남호;정현규;손익부
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2017년도 추계학술대회
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    • pp.711-713
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    • 2017
  • 본 논문에서는 800nm급 펨토초 레이저와 위상마스크를 이용하여 게르마늄이 첨가된 일반 광섬유(Corning SMF-28)에 FBG 센서를 가공하였다. 제작된 FBG 센서는 누적방사선 100 kGy급 감마선에 조사하여 방사선 영향을 평가하였다. fs-FBG-2 센서는 방사선 조사 중에 불완전한 광특성을 보였지만, fs-FBG-1 센서는 누적선량 100kGy에서 Bragg 파장변화가 10pm 이하로 나타나 뛰어난 내방사선 특성을 보였다.

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의료기기의 발전을 위한 탄소소재의 활용 (Application of Carbon Materials for the Development of Medical Devices)

  • 곽영곤
    • 핵의학기술
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    • 제27권1호
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    • pp.23-28
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    • 2023
  • Carbon materials are widely used in many areas of our lives. A fiber having a carbon content of 90% or more obtained by heating an organic fiber precursor is referred to as a "carbon fiber". Carbon fibers are currently used in the medical market to manufacture radiation transmission device parts, artificial joints, and medical aids, as many developments have been made to utilize carbon fibers' characteristics such as light weight, radiation permeability, biocompatibility, high strength, high heat resistance, thermal conductivity, and electrical conductivity. In order to maintain body temperature and increase immunity in long-lasting nuclear medical examination and treatment through the idea of convergence of carbon materials and radiation technology, the quality of medical services can be improved by utilizing carbon materials. We should be aware of the domestic carbon-based medical device industry and make efforts to contribute to the development of medical devices. As a radiation expert, we should try to use our skills and experience to find items that can be fused with medical devices to develop various nuclear medical examination fields and radiographic examination fields that can be widely applied. We should actively engage in future technology development and carbon material research to strengthen the global competitiveness of the domestic medical device industry and improve the quality of medical services.

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흑연 및 탄소나노튜브 혼합 방열도료의 특성 (Characteristics of Thermal Radiation Pastes Containing Graphite and Carbon Nanotube)

  • 이지훈;송만호;강찬형
    • 한국표면공학회지
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    • 제49권2호
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    • pp.218-224
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    • 2016
  • Thermal radiation pastes were prepared by dispersing carbon materials as fillers with a content of 1 weight percent in an acrylic resin. The kind of fillers was as follows; $25{\mu}m$ graphite, $45{\mu}m$ graphite, $15{\mu}m$ carbon nanotube(CNT), a 1:1 mixture of $25{\mu}m$ graphite and $15{\mu}m$ CNT, and a 1:1 mixture of $45{\mu}m$ graphite and $15{\mu}m$ CNT. Thermal emissivity was measured as 0.890 for the samples with graphite only, 0.893 for that with CNT only, and 0.892 for those containing both. After coating prepared pastes on a side of 0.4 mm thick aluminium plate and placing the plate over an opening of a box maintained at $92^{\circ}C$ with the coated side out, the temperatures on the uncoated side of the plates were measured. The samples containing graphite and CNT showed the lowest temperatures. The paste with mixed fillers was coated on the back side of the PCB of an LED module and thermal analysis was carried out using Thermal Transient Tester (T3ster) in a still air box. The thermal resistance of the module with coated PCB was measured as 14.34 K/W whereas that with uncoated PCB was 15.02 K/W. The structure function analysis of T3ster data revealed that the difference between junction and ambient temperatures was $13.8^{\circ}C$ for the coated case and $18.0^{\circ}C$ for the uncoated. From the infrared images of heated LED modules, the hottest-spot temperature of the module with coated PCB was lower than that of the uncoated one for a given period of LED operation.

방사선 내성 세균 Flavisolibacter tropicus LCS9T의 완전한 게놈 서열 (Complete genome sequence of Flavisolibacter tropicus LCS9T, a radiation resistant bacterium)

  • 김명겸;손은화;정희영;스리니바산 사티야라지
    • 미생물학회지
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    • 제54권1호
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    • pp.87-89
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    • 2018
  • Flavisolibacter tropicus $LCS9^T$은 한국 중서부에 위치한 서천 국립생태원 에코리움 내 열대관 토양에서 분리되었다. 이 연구에서 G + C 함량이 41.5%인 5,940,863 bp 의 원형 염색체로 구성된 Flavisolibacter tropicus $LCS9^T$ 의 완전한 게놈서열을 분석하였다. 이 완전한 게놈서열은 5,075 개의 유전자, 337개의 위유전자 그리고 59 개의 rRNA 유전자를 포함하고 있다. 유전체 특징은 감마선 및 UVC 에 대응하는 주요 효소를 포함하였다.