• Journal of the Korean Society of Food Science and Nutrition
• /
• v.37 no.9
• /
• pp.1136-1141
• /
• 2008

This study was to investigate antiwrinkle effect of mugwort (Artemisia vulgaris) methanol extract in hairless mouse skin induced by UVB-irradiation. Hairless mouse were topically treated with the basic lotion alone (control), ascorbic acid (AA-0.5%, AA-1.0%, AA-2.0%, and AA-5.0%) and mugwort extract (ME-0.5%, ME-1.0%, ME-2.0%, and ME-5.0%) dissolved in a basic lotion. After topical treatment of 30 minutes, the animals were irradiated with increasing doses of UVB radiation ($60{\sim}100\;mJ/cm^2$) for 4 weeks. In our experimental condition, skin thickness of hairless mouse was significantly decreased ($12.5{\sim}21.4%$) in all ME groups compared with control group. Ra value, that is surface roughness parameter induced by skin wrinkling, was significantly decreased ($23.7{\sim}31.1%$) in ME-1.0%, 2.0% and 5.0% group compared with control group. Furthermore, Rq, Rz and Rt value were significantly decreased to $11.2{\sim}21.2%$, $19.8%{\sim}24.5%$, and $14.2%{\sim}22.7%$, respectively. Wrinkle formation of ascorbic acid treatment group as reference group was inhibited, but its effect was less than ME treatment. Matrix metalloproteinase-1 activity was significantly inhibited ($19.7{\sim}22.6%$) compared with control group and collagen content was significantly increased (about 10%) when compared with control group. These results indicate that ME could protect skin aging and wrinkle formation in hairless mouse from photo-irradiation.

• Analytical Science and Technology
• /
• v.29 no.3
• /
• pp.114-125
• /
• 2016

In this study, 165 wastewater discharge facilities in 10 business types were investigated with regard to 24 specific hazardous substances that included heavy metals, VOCs, CN, and phenol in the Gwangju city. Cu in the range from from 0.008 to 35.420 mg/L was detected in all business types and the detection rate was 46.8 %. Other heavy metals, such as Cd, As, Hg, Pb, and Cr⁺⁶ were detected as well. However, their detection rates ranged between 0.6 and 1.8 %. CN and phenol were detected in one and five facilities, respectively. 12 species of VOCs were detected: chloroform 80.6 % (0.42 to 81.60 μg/L), benzene 16.4 % (1.49 to 3.31 μg/L), trichloroethylene 11.5 % (1.78 to 6.02 μg/L), 1,1-dichloroethylene 10.3 % (1.23 to 5.89 μg/L), and dichloromethane 8.5 % (0.28 to 968.86 μg/L) in the detection rate order. The concentration of VOCs was detected in trace amounts, except for dichloromethane that exceeded the effluent quality standard in three business types, namely, metal manufacturing, food industry, and car washing facility. Chloroform was detected in all business types, where 24.88 μg/L were detected in the laundry business and 53.41 μg/L in the water supply business; the mean concentration of chloroform in these two business types was higher than elsewhere. Therefore, for the disposal of non-degradable specific hazardous substances in industrial wastewater, it is necessary to introduce physical and chemical processes, such as activated carbon adsorption, fenton oxidation, ozone treatment, as well as photocatalyst and the UV radiation.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.43 no.6
• /
• pp.884-892
• /
• 2014

The purpose of this study was to investigate the drying characteristics and drying models of Ainsliaea acerifolia Sch. Bip. using far-infrared thin layer drying. Far-infrared thin layer drying test on Ainsliaea acerifolia Sch. Bip. was conducted at two air velocities of 0.6 and 0.8 m/sec, as well as three drying temperatures of 40, 45, and $50^{\circ}C$ respectively. The drying models were estimated using coefficient of determination and root mean square error. Drying characteristics were analyzed based on factors such as drying rate, leaf color changes, antioxidant activity, and contents of polyphenolics and flavonoids. The results revealed that increases in drying temperature and air velocity caused a reduction in drying time. The Thompson model was considered suitable for thin layer drying using far-infrared radiation for Ainsliaea accerifolia Sch. Bip. Greenness and yellowness values decreased and lightness values increased after far-infrared thin layer drying, and the color difference (${\Delta}E$) values at $40^{\circ}C$ were higher than those at $45^{\circ}C$ and $50^{\circ}C$. The antioxidant properties of Ainsliaea acerifolia Sch. Bip. decreased under all far-infrared thin layer drying conditions, and the highest polyphenolic content (37.9 mg/g), flavonoid content (22.7 mg/g), DPPH radical scavenging activity (32.5), and ABTS radical scavenging activity (31.1) were observed at a drying temperature of $40^{\circ}C$ with an air velocity of 0.8 m/sec.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.31 no.5
• /
• pp.910-916
• /
• 2002

As the utilization of medicinal herbs in food and bio-industry increases, safe hygienic technologies for them are demanded. To consider the possibility of application of radiation technology for this purpose, the genotoxi-cological safety of three r -irradiated medicinal herbs were studied. Astragali Radix, Atractylodes Rhizoma and Cimicifugae Rhizoma were irradiated at 10 kGy, and then were extracted with hot water. The genotoxicity of the extracts was examined in two short-term in vitro tests: (1) Salmonella reversion assay (Ames test) in strains of TA98 and TA100; (2) Micronucleus test in cultured Chinese hamster ovary (CHO) cells. The extract was treated at maximum doses of 5 mg/plate in Salmonella reversion assay, and 1 mg/mL in micronucleus test where growth of CHO cells was inhibited by 50%. In Salmonella reversion assay with or without metabolic activation, both ex-tracts of irradiated and non-irradiated herbs showed no significant differences in formation of revertant colonies compared with the negative control. And also in micronucleus test, the incidences of micronucleus in CHO cells cultured with extracts of irradiated herbs were almost same as negative control in less than 3%. These results of two in vitro tests suggest that ${\gamma}$-irradiated herbs do not show mutagenicity and cytogenetic toxicity. Further tests of in vivo genotoxicity and chronic toxicity are needed to ascertain the safety of ${\gamma}$-irradiated herbs.

• Korean Journal of Food Science and Technology
• /
• v.41 no.6
• /
• pp.694-699
• /
• 2009

The antimutagenic activities of ethanol extracts of Korean and American propolis were tested using Salmonella Typhimurium TA98 with two indirect mutagens of 3-amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) and 2-aminoanthracene (2-AA) with S9 mix. Additionally, their antimicrobial activities against acne-related pathogenic strains of Propionibacterium acnes, Staphylococcus Epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa were evaluated using both paper disk method and agar dilution method. Ethanol extracts of Korean and American propolis showed strong inhibitory effects, in a dose dependant manner, against the mutagenicities induced by Trp-P-1 and 2-AA. The antimutagenic effect of ethanol extracts of Korean propolis showed significantly higher protective activity than that of American propolis against the Trp-P-1 induced mutagenicity of S. Typhimurium TA98 at the lower concentration ($1-10\;{\mu}g$), but significantly lower protective activity at the higher concentration ($50-200\;{\mu}g$). The antimutagenic effect of ethanol extract of Korean propolis showed significantly higher protective activity than that of American propolis against the 2-AA induced mutagenicity at the concentration of $1\;{\mu}g$, but significantly lower protective activity than that of the American at the higher concentration ($50-200\;{\mu}g$). Both extracts showed strong antimicrobial activities against all the acne-related pathogens tested, with minimal inhibitory concentration (MIC) values in the range $1,500-5,000\;{\mu}g/mL$.

• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.1 no.2
• /
• pp.57-61
• /
• 1987

The characteristis of all the instruments and materials used in atomic industry are changed due to irradiation damages by the effects of radiation activities. In this study when R-C series-parallel circuits are irradiated by $\gamma$-ray, variations in its electrical properties have been investigated. The following results are obtained. 1) In the R-C series circuit, the impedance variation ratio is increased as the irradiation quantity is increased up to $10^6[r]$, and above $10^6[r]$, the impedance variation ratio reached at the saturated condition. In the saturated condition, the increasing value was about 1.25 (%). 2) In the R-C series circuit, the power factor variation ratio is decreased as the irradiation quantity is in creased up to $10^6[r]$, and above $10^6[r]$, the power factor variation ratio reached at the saturated condition. In the saturated condition, the decreasing value was about 0.5(%). 3) In the R-C parallel circuit, the impedance variation ratio is increased as the irradiation quentity is increased up to $10^6[r]$, and above $10^6[r]$, the impedance variation reached at the saturated condition. In the saturated condition, the increasing value was about 0.5.(%). 4) In the R-C parallel circuit, the power factor variation ratio is decreased as the irradiation quantity is increased up to $10^6$[r], and above $10^6$[r], the power factor variation ratio reached at the saturated condition. In the saturated condition, the decreasing value was about 1.3(%).

• Journal of Environmental Science International
• /
• v.19 no.11
• /
• pp.1397-1405
• /
• 2010

Mass mortalities of cultivated organisms have occurred frequently in Korean coastal waters causing enormous losses to cultivating industry. The preventive measures require continuous observation of farm environment and real-time provision of data. However, line hanging aquaculture farm are generally located far from monitoring buoys and has limitations on installation of heavy equipments. Substituting battery pack for solar panels and miniaturizing size of buoy, newly developed system can be attached to long line hanging aquaculture farm. This system could deliver measured data to users in real-time and contribute to damage mitigation and prevention from mass mortalities as well as finding their causes. The system was installed off Gijang and Yeongdeck in Korea, measuring and transmitting seawater temperature at the sea surface every 30 minutes. Short term variation of seawater temperature, less than one day, in Gijang from June to July 2009 corresponded tidal period of about 12 hours and long term variation seemed to be caused by cold water southeast coast of Korea, particularly northeast of Gijang. Seawater temperature differences between Gijang station and the other station that is about 500 m away from Gijang station were $1^{\circ}C$ on average. This fact indicates that it is need to be pay attention to use substitute data even if it is close to the station. Daily range of seawater temperature, one of crucial information to aquaculture, can be obtained from this system because temperature were measured every 30 minutes. Averages of daily range of temperature off Gijang and Yeongdeok during each observation periods were about $2.9^{\circ}C$ and $4.7^{\circ}C$ respectively. Dominant period of seawater temperature variation off Yeongdeok was one day with the lowest peak at 5 a.m. and the highest one at 5 p.m. generally, resulting from solar radiation.

• Fashion & Textile Research Journal
• /
• v.7 no.3
• /
• pp.315-320
• /
• 2005

With regard to the fact that temperature of human body remains almost constant at $37^{\circ}C$, changes by circadian variation, this study intended to investigate the effect of circadian rhythm on physiological responses of human body according to body fat rate. Fifteen healthy adult women were recruited for this study and were measured body fat as a method of bio impedance. We organized subjects into three groups ; low body fat group(group L-less than 20% of body fat), medium body fat group(group M-20%~30% of body fat) and high body fat group(group H-more than 30% of body fat). The experiment was carried out in a climate chamber of $32^{\circ}C$, 60% RH with the repeat of 'Exercise' and 'Rest' period. Subjects participated in two experiments, one is morning experiment(called 'AM'), the other is afternoon experiment (called 'PM'). The results of this study are as follows ; As to the variation of rectal temperature, group L and M had a significant difference in the time of the day between AM and PM, but group H had almost the same rectal temperature in the two kinds of experimental time. The reason why group H had a smaller difference in the circadian rhythm of rectal temperature in this study is estimated at the Budd et al.(1991)'s results that body fat had effects on reduction in thermogenesis, radiation, mean skin temperature, and increase in insulation of the tissues. Group M had the highest mean skin temperature in the 'PM'. All the 3 groups didn't have stable values in 'AM'. But it showed more stable in 'PM' than 'AM'. Sweat rate was the highest in group H in both 'AM' and 'PM'. Group M had larger sweat rate in 'PM' than 'AM'. but in group L and H, sweat rate was almost the same in two kinds of time of the day. This result suggests that who have more or less body fat have larger difference in sweat rate between morning and afternoon than who have normal body fat.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.39 no.2
• /
• pp.141-148
• /
• 2013

The harmful effects of ultraviolet (UV) radiation by increasing sun exposure are making people use sunscreens casually. To keep pace with this trend, many researches about mixing different ingredients or extracting effective ingredients from natural materials are conducted by cosmetics industry. In the present study, we evaluated the UV blocking effect of the sunscreen containing Scutellaria baicalensis Georgi extract. 10 volunteers were measured by minimal erythema dose (MED) and sun protection factor (SPF) of each product. The SPF results were $34.52{\pm}2.13$ and $32.67{\pm}1.44$ in the sunscreen containing Scutellaria baicalensis Georgi extract and that of not containing the substance, respectively. Although the difference of SPF between two products was statistically not significant, it is thought to be meaningful in evaluating clinical effects of the sunscreen using natural substance to humans without any adverse reaction.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.41 no.4
• /
• pp.351-359
• /
• 2015

Acute and chronic ultraviolet (UV) irradiation triggers severe skin photoaging processes, which directly disrupt the normal three-dimensional integrity of skin. UV light stimulates the expression of matrix metalloproteinases (MMPs) which degrade constituents of extracellular matrix (ECM) proteins. These MMPs reduce collagen synthesis and decrease skin elasticity and integrity, resulting in wrinkle formation. In this study, we identified Rosa multiflora hip extract (RME) as an effective anti-photoaging ingredient. First, cell proliferation activity of RME was verified using Hs68 human dermal fibroblast cell line. RME downregulated MMPs expression through the inhibition of activator protein (AP)-1. In addition, type I and IV collagen expressions were increased with RME treatment and UVB-induced inflammatory responses were also reduced after RME treatment. In conclusion, R. multiflora hip extract may effectively improve UVB-induced skin aging and wrinkle formation which may provide as an anti-aging, anti-wrinkle, and anti-inflammation ingredient in cosmetic industry.