• Ocean and Polar Research
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• v.39 no.1
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• pp.35-43
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• 2017

Concentrations of dissolved organic carbon (DOC), dissolved organic nitrogen (DON), dissolved organic phosphate (DOP), and colored dissolved organic matter (CDOM) were measured in the coastal sea off inland aqua farms in northeastern Jeju Island in summer 2015. The highest concentrations of DOC, DON, and DOP were revealed in the surface water off Hado-ri where the lowest salinity conditions prevailed (31.6). The concentrations of DOC, DON, and DOP in the surface water were lower in the inner stations (SH1-1, 1-2, and 1-3) near the aqua farms of the Haengwon-ri than in the outer stations. The concentrations of DOC, DON, and DOP negatively correlated with salinity. These results indicate that the contribution of dissolved organic matter (DOM) from the aqua farms seems to be not significant. On the other hand, the higher concentrations of DON and DOP in the inner stations of Hado-ri (HD 1-1) seem to be attributed to excrement of migrating birds. The three components of CDOM (T, M, and C peaks) showed no relationship with salinity, perhaps due to various in situ productions by marine organisms and decomposition by ultraviolet radiation. The observed lower C:M ratio, an indicator of terrestrial source, and the higher biological index (BIX) of CDOM in the station off Hado-ri indicate that DOM is produced mainly by biological activity. Based on the higher humification index (HIX) of CDOM and the higher DOC:DON ratio off Haengwon-ri, refractory DOM in the inland aqua farms is likely transported to the coastal sea.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.245-252
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• 2014

Human METCAM/MUC18, a cell adhesion molecule (CAM) in the immunoglobulin-like gene super family, plays a dual role in the progression of several epithelium cancers; however, its role in the nasopharyngeal carcinoma (NPC) remains unclear. To initiate the study we determined human METCAM/MUC18 expression in tissue samples of normal nasopharynx (NP), NPCs, and metastatic lesions, and in two established NPC cell lines. Immunoblotting analysis was used for the determination in lysates of frozen tissues, and immunohistochemistry (IHC) for expression in formalin-fixed, paraffin-embedded tissue sections of 7 normal nasopharynx specimens, 94 NPC tissue specimens, and 3 metastatic lesions. Human METCAM/MUC18 was expressed in 100% of the normal NP, not expressed in 73% of NPC specimens (or expressed at very low levels in only about 27% of NPC specimens), and expressed again in all of the metastatic lesions. The level of human METCAM/MUC18 expression in NPC tissues was about one fifth of that in the normal NP and metastatic lesions. The low level of human METCAM/MUC18 expression in NPC specimens was confirmed by a weak signal of RT-PCR amplification of the mRNA. Low expression levels of human METCAM/MUC18 in NPC tissues were also reflected in the seven established NPC cell lines. These findings provided the first evidence that diminished expression of human METCAM/MUC18 is an indicator for the emergence of NPC, but increased expression then occurs with metastatic progression, suggesting that huMETCAM/MUC18, perhaps similar to TGF-${\beta}$, may be a tumor suppressor, but a metastasis promoter for NPC.

• KIEAE Journal
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• v.12 no.2
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• pp.65-75
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• 2012

The rapid urbanization caused drastic temperature changes in Korea. Excessive urbanization and development result in unpredictable and abnormal climate change all over the world. These changes are reflected in Korean government policy and research about cities, such that various research endeavors have been undergone recently. There are lots of ways to improve the urban environment; the easiest way to solve the urban heat effect problem is to make green spaces within the city. Even though we can't enlarge green spaces over the city limitlessly, it is desperately need for a methodology to efficiently create green space in limited area. Based on awareness of issues as mentioned earlier, we would like to propose landscaping method that can increase thermal comfort in the same area. For this study, simulating the change of temperature, mean radiant temperature, PMV were done due to number of species planted in apartment complex. To increase the reliability of the simulation, first above all, field measurement for temperature change was performed in apartment complex, where residential building are arranged in the form of ㄷ. And based on this data, Envi-met simulation was performed varying 1-7 kinds of species divided by grass, shrubs, arbor (deciduous, conifers) planted in apartment complex. As a result, there was a change less than $1^{\circ}C$ with the increasing number of species in daytime, but the average radiation temperature about $6-7^{\circ}C$ was reduced. In addition, PMV index was improved by more than 0.5 point. Thermal comfort indicator improved significantly depending on the number of species during the day, on the other hand, there were no significant changes at night. As a consequence, this study has shown that not single-species planting but mixed planting varied the number of species would improve the thermal comfort in the same area of landscaping space at daytime.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2003.11a
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• pp.232-235
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• 2003

In general, the parameters of climate change include aerosol chemical compounds, aerosol optical depth, greenhouse gases(carbon dioxide, CFCs, methane, nitrous oxide, tropospheric ozone), ozone distribution, precipitation acidity and chemical compounds, persistent organic pollutants and heavy metals, radioactivity, solar radiation including ultra-violet and standard meteorological parameters. Over the last ten years, the monitoring activities of Korea regarding to the climate change have been progressed within the WMO GAW and ACE-Asia IOP programs centered at the observation sites of Anmyeon and Jeju Gosan islands respectively. The Greenhouse gases were pointed out that standard air quality monitoring techniques are required to enhance data comparability and that data presentation formats need to be harmonized and easily understood. Especially, the impact of atmospheric aerosols on climate depends on their optical properties, which, in turn, are a function of aerosol size distribution and the spectral reflective indices. Aerosol optical depth and single scattering albedo in the visible are used as the two basic parameters in the atmospheric temperature variation studies. The former parameter is an indicator of the attenuation power of aerosols, while the latter represents the relative strength of scattering and absorption by aerosols. For aerosols with weak absorption, surface temperature decreases as the optical depth increases because of the domination of backscattering. For aerosols with strong absorption, however, warming could occur as the optical depth increases. The objective of the study is to characterize the means, variability, and trends of Greenhouse gases and aerosol properties on a regional basis using data from its baseline observatories in Korea peninsula. A further goal is to understand the factors that control radiative forcing of the greenhouse and aerosol.

• Korean Journal of Digital Imaging in Medicine
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• v.13 no.3
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• pp.139-144
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• 2011

The purpose of this report is recommending a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The experiment was performed with mobile digital X-ray unit and used a acrylic phantom for exposure index measurement. Exposure modality was kVp, mAs, SID. After every exposure, make a data sheet for characteristic curve of detector response. The equipment performed Mobile digital X-ray unit provide the user with values ralated to the incident exposure(air kerma)to the digital detector. They are showed as a logarithmic function shaped. As a result, DEI means a relative measure of exposure to the detector, as compared to the expected exposure for a particular anatomical view. Radiographic technique is the combination of factors used to exposure an anatomical part to produce a high quality radiography and technique charts used most commonly by radiographers to produce consistently exposure level which patient dose can be kept acceptably low.

• Journal of the Korean Society of Radiology
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• v.9 no.2
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• pp.121-124
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• 2015

Digital Mammography is very important for the early diagnosis of breast cancer. but excessive radiation dose to the patient may increase the probability of occurrence of breast cancer. absorbed dose rate and signal, noise, and contrast in accordance with the change of the filter, and analyzed the signal-to-noise ratio. absorbed dose rate GE Equipment is higher than that of Siemens and Hologic. using the material of Mo / Mo was lower than the other target-filter combination. SNR of Siemens equipment is high and measured high when Mo / Mo selected, the other two devices was measured high when Mo / Rh selected. when you choose a target-filter combination our results will be a good indicator.

• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.2
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• pp.110-115
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• 2010

This study was conducted to estimate the feasibility using thermal image measurement that is applicable to internal leak diagnosis for the power plant valve. Abnormal heating of valve surface associated with high temperature steam f10w toward valve outlet side in the condition of low temperature is a primary indicator of leakage problems in high temperature and pressure valves. Thermal imaging enables to see the invisible thermal radiation that may portend impending damage before their condition becomes critical. When steam flow in valve outlet side in the condition of low temperature is converted into heat transmitted through the valve body due to the internal leakage in valve. The existence of abnormally increasable leakage rate in the valve will result in abnormally high levels of heat to be generated that can be quickly identified with a thermal image avoiding energy loss or damage of valve component. From the experimental results, it was suggested that the thermal image measurement could be an effective way to precisely diagnose and evaluate internal leak situation of valve.

• Korean Journal of Clinical Pharmacy
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• v.31 no.2
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• pp.115-124
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• 2021

Background: With an increase in the number of breast cancer survivors, greater importance is attached to health-related quality of life, particularly pain and symptom control. This study aimed to identify the factors that are associated with pain in cancer patients based on the patterns of prescribing opioid, non-opioid, and adjuvant analgesics. Methods: This analysis included new patients who had developed breast cancer between 2003 and 2012. The degree of pain was analyzed based on the socio-demographic (age, income quintile, number of hospitalizations, and duration of disease), indicator (Body Mass Index; BMI, Charlson Comorbidity Index; CCI, Cumulative Analgesic Consumption Score; CACS), operation (mastectomy, lymph node dissection), and therapy (chemotherapy, radiation therapy), as well as complication-related variable (lymphedema). Results: As for the patterns of prescribing analgesics by stages, non-opioid and opioid analgesics constituted 30.7 and 69.3%, respectively. The mean value and variance of CACS were 5.596 and 12.567, respectively. The factors that significantly affected the degree of pain were age (≥50; IRR: 1.848, 95% CI 1.564-2.184, p=0.000), income quintile (IRR: 0.964, 95% CI 0.938-0.991, p=0.008), BMI (≥ 25; IRR: 1.479, 95% CI 1.222-1.795, p=0.000), CCI (≥ 4; IRR: 1.649, 95% CI 1.344-2.036, p=0.000), and lymphedema (yes; IRR: 1.267, 95% CI 1.006-1.610, p=0.047). Conclusions: It is necessary to develop systematic and comprehensive pain control measures to improve the quality of life for breast cancer survivors, especially for those who are 50 years or older, lie in the lower-income quintile, have BMI of ≥25 and CCI score ≥ 4, or have lymphedema.

• Journal of the Korean Society of Radiology
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• v.17 no.4
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• pp.565-572
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• 2023

This study was conducted to analyze the status radiological imaging examinations assessment in Korea medical institutions conducted in the public sector and suggest a direction for improvement. Among the assessment of medical institutions, the main assessment related to radiographic imaging examinations are the certification evaluation of medical institutions and the adequacy assessment of radiographic imaging examinations. The certification evaluation of medical institutions evaluates the image inspection operation process, provision of accurate results, and compliance with safety management procedures. In the assessment of adequacy of radiographic imaging examinations, structural indicators related to manpower and equipment, patient evaluation implementation rate, and exposure reduction programs were included. However, for safer and higher-quality radiological imaging examinations, it is necessary to increase the participation rate of medical institutions in certification evaluations. In addition, it is necessary to improve the manpower indicator, and incentive payments can be considered to induce quality improvement of medical institutions in the future. Integrated management of radiation exposure at the national level should also be carried out simultaneously.

• The Korean Journal of Nuclear Medicine
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• v.29 no.3
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• pp.343-349
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• 1995

Background : For biological dosimetry of radiation exposure, both observing hematologic change and calculating Ydr by chromosomal analysis as biological indicators are widely used. However, due to the lack of studies on biological dosimetry of radiation dose absorbed in the body such as in the cases of radioactive iodine therapy, the maximal and safe dose is not well known, nor is the extent to which the body can safely endure radiation exposure. Purpose : To investegate the practical applicability of hematologic changes and Ydr as an indicator for estimating radiation exposure, to patients with thyroid diseases after doses of radioactive iodine. Material and Methods : 5 patients with hyperthyroidism and 35 patients who have had thyroid cancer operation were under treatment with radioactive iodine, changes in number of lymphocytes were tracked and Ydr was calculated for more than 2 months by chromosomal analysis in peripheral lymphocytes. Results ; 1) The number of lymphocytes began to decrease 2 weeks after doses of radioactive iodine, and reached the nadir after 6 and 8 weeks, then gradually recovered. 2) The nadir count of lymphocytes was reversely correlated with the administered dosage of radioactive iodine. 3) Ydr was generally stable between 2 and 8 weeks. 4) The maximal value of Ydr was correlated with the administered dosage of radioactive iodine. 5) Ydr value at the 2nd week increased with augmented dosage of radioactive iodine. 6) Ydr value at the 2nd week was correlated with fall of lymphocyte count. Conclusion : Patients must be closely observed, because temporary bone marrow suppression and slight chromosomal aberration can be produced by even generally used dosages of radioactive iodine for diagnosis and therapy. Maximal percent fall of lymphocyte count, Ydr at the 2 week interval and maximal Ydr can be used as the biological predictor of administered dosage of radioactive iodine.