• Title/Summary/Keyword: Radiation dose

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Buildup Characteristics of Radiophotoluminescent Glass Dosimeters with Exposure Time of X-ray (엑스선의 조사시간에 따른 형광유리선량계의 빌드업 특성)

  • Kweon, Dae Cheol
    • Journal of Biomedical Engineering Research
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    • v.38 no.5
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    • pp.256-263
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    • 2017
  • By using the buildup characteristics of the radiophotoluminescence glass dosimeter(RPLGD), it is aimed to help the measurement of the accurate dose by measuring the radiation dose according to the time of the glass element. Five glass elements were arranged on the table and the source to image receptor distance(SID) was set to 100 cm for the build-up radiation dose measurement of the fluorescent glass dosimeter glass element(GD-352M). Radiation doses and saturation rates were measured over time according to irradiation time, with the tube voltage (30, 60, 90 kVp) and tube current (50, 100 mAs) Repeatability test was repeated ten times to measure the coefficient of variation. The radiation dose increased from 0.182 mGy to 12.902 mGy and the saturation rate increased from 58.3% with increasing exposure condition and time. The coefficient of variation of the glass elements of the fluorescent glass dosimeter was ranged from 0.2 to 0.77 according to the X - ray exposure conditions. X - ray exposure showed that the radiation dose and saturation rate were increased with buildup characteristics, and degeneration of glass elements was not observed. The reproducibility of the variation coefficient of the radiation generator was included within the error range and the reproducibility of the radiation dose was excellent.

Low-Dose Radiation Stimulates the Proliferation of Normal Human Lung Fibroblasts Via a Transient Activation of Raf and Akt

  • Kim, Cha Soon;Kim, Jin Kyoung;Nam, Seon Young;Yang, Kwang Hee;Jeong, Meeseon;Kim, Hee Sun;Kim, Chong Soon;Jin, Young-Woo;Kim, Joon
    • Molecules and Cells
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    • v.24 no.3
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    • pp.424-430
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    • 2007
  • The biological effects of low-dose radiation have been investigated and debated for more than a century, but its cellular effects and regulatory mechanisms remain poorly understood. This study shows the human cellular responses to low-dose radiation in CCD-18 Lu cells, which are derived from normal human lung fibroblasts. We examined a colony-forming assay for cell survival by ionizing radiation. Live cell counting and cell cycle analysis were measured for cell proliferation and cell cycle progression following low-dose irradiation. We examined Raf and Akt phosphorylation to determine the proliferation mechanism resulting from low-dose radiation. We also observed that p53 and p21 were related to cell cycle response. We found that 0.05 Gy of ionizing radiation enhanced cell proliferation and did not change the progression of the cell cycle. In addition, 0.05 Gy of ionizing radiation transiently activated Raf and Akt, but did not change phospho-p53, p53 and p21 in CCD-18 Lu cells. However, 2 Gy of ionizing radiation induced cell cycle arrest, phosphorylation of p53, and expression of p53 and p21. The phosphorylation of Raf and Akt proteins induced by 0.05 Gy of ionizing radiation was abolished by pre-treatment with an EGFR inhibitor, AG1478, or a PI3k inhibitor, LY294002. Cell proliferation stimulated by 0.05 Gy of ionizing radiation was blocked by the suppression of Raf and Akt phosphorylation with these inhibitors. These results suggest that 0.05 Gy of ionizing radiation stimulates cell proliferation through the transient activation of Raf and Akt in CCD-18 Lu cells.

Measurement of the Natural Radiation Dose in the Ski Field (Focusing on the Gyeonggi Province area) (스키장의 자연방사선량 측정(경기도 지역을 중심으로))

  • Jung, Hongmoon;Jung, Jaeeun
    • Journal of the Korean Society of Radiology
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    • v.11 no.3
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    • pp.117-122
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    • 2017
  • With the increase in leisure life, the population of ski resorts is rapidly increasing. The activity at the ski resort is likely to receive a direct chance of natural sunlight or space ray. Because it is located in the mountains where altitude exists. As a general rule, it is widely known that the higher the elevation rate, the more increasing the natural radiation dose. However, the natural radiation dose rate for the ski slopes has not been reported yet. Various ski resorts exist in Korea, but this study had chose 4 ski resorts to measure the natural dose of natural radiation. As a result, the natural radiation dose for the ski slope was measured at a relatively high dose of ordinary living areas. However, the level of natural radiation dose was not worrisome. It is recommended to wear ski wear or goggles to minimize natural radiation exposure at the ski slopes.

The effect of photon energy on intensity-modulated radiation therapy (IMRT) plans for prostate cancer

  • Sung, Won-Mo;Park, Jong-Min;Choi, Chang-Heon;Ha, Sung-Whan;Ye, Sung-Joon
    • Radiation Oncology Journal
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    • v.30 no.1
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    • pp.27-35
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    • 2012
  • Purpose: To evaluate the effect of common three photon energies (6-MV, 10-MV, and 15-MV) on intensity-modulated radiation therapy (IMRT) plans to treat prostate cancer patients. Materials and Methods: Twenty patients with prostate cancer treated locally to 81.0 Gy were retrospectively studied. 6-MV, 10-MV, and 15-MV IMRT plans for each patient were generated using suitable planning objectives, dose constraints, and 8-field setting. The plans were analyzed in terms of dose-volume histogram for the target coverage, dose conformity, organs at risk (OAR) sparing, and normal tissue integral dose. Results: Regardless of the energies chosen at the plans, the target coverage, conformity, and homogeneity of the plans were similar. However, there was a significant dose increase in rectal wall and femoral heads for 6-MV compared to those for 10-MV and 15-MV. The $V_{20Gy}$ of rectal wall with 6-MV, 10-MV, and 15-MV were 95.6%, 88.4%, and 89.4% while the mean dose to femoral heads were 31.7, 25.9, and 26.3 Gy, respectively. Integral doses to the normal tissues in higher energy (10-MV and 15-MV) plans were reduced by about 7%. Overall, integral doses in mid and low dose regions in 6-MV plans were increased by up to 13%. Conclusion: In this study, 10-MV prostate IMRT plans showed better OAR sparing and less integral doses than the 6-MV. The biological and clinical significance of this finding remains to be determined afterward, considering neutron dose contribution.

PRIMORDIAL RADIONUCLIDES DISTRIBUTION AND DOSE EVALUATION IN UDAGAMANDALAM REGION OF NILGIRIS IN INDIA

  • Manikandan, N.Muguntha;Selvasekarapandian, S.;Sivakumar, R.;Meenakshisundaram, V.;Raghunath, V.M.
    • Journal of Radiation Protection and Research
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    • v.26 no.3
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    • pp.183-190
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    • 2001
  • The activity concentration of primordial radionuclides i.e., $^{238}U$ series, $^{232}Th$ series and $^{40}K$, in soil samples collected from Udagamandalam environment, have been measured by employing NaI (Tl) Gamma ray Spectrometer. The absorbed gamma dose rate has also been simultaneously measured by using both Environmental Radiation Dosimeter at each soil sampling location (ambient gamma dose) as well as from the gamma dose derived from the activity concentration of the primordial radionuclides. The results of activity concentration of each radio nuclides in soil, absorbed dose rate in air due to soil activity and possible cosmic radiation at each location along with human effective dose equivalent for Udagamandalam environment are presented and discussed.

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Patient Radiation Exposure Dose in Computed Tomography (전산화단층촬영장치에서 환자피폭선량)

  • Cho, Pyong Kon
    • Journal of the Korean Society of Radiology
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    • v.9 no.2
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    • pp.109-115
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    • 2015
  • In case of a CT examinations, there is a difference in the distribution of radiation dose from that of general X-ray equipments, and it has been known to cause a great radiation exposure during the examinations. However, owing to its high reliability on the accuracy of a examinations result, its use has increased continuously. In consideration of such a circumstance, the CT equipment, radiation dose during CT examinations, diagnostic reference level, and solutions to reduce radiation dose were mentioned on the basis of previously reported data.

Use of big data for estimation of impacts of meteorological variables on environmental radiation dose on Ulleung Island, Republic of Korea

  • Joo, Han Young;Kim, Jae Wook;Jeong, So Yun;Kim, Young Seo;Moon, Joo Hyun
    • Nuclear Engineering and Technology
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    • v.53 no.12
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    • pp.4189-4200
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    • 2021
  • In this study, the relationship between the environmental radiation dose rate and meteorological variables was investigated with multiple regression analysis and big data of those variables. The environmental radiation dose rate and 36 different meteorological variables were measured on Ulleung Island, Republic of Korea, from 2011 to 2015. Not all meteorological variables were used in the regression analysis because the different meteorological variables significantly affect the environmental radiation dose rate during different periods, and the degree of influence changes with time. By applying the Pearson correlation analysis and stepwise selection methods to the big dataset, the major meteorological variables influencing the environmental radiation dose rate were identified, which were then used as the independent variables for the regression model. Subsequently, multiple regression models for the monthly datasets and dataset of the entire period were developed.

Development of Internal Dose Assessment Procedure for Workers in Industries Using Raw Materials Containing Naturally Occurring Radioactive Materials

  • Choi, Cheol Kyu;Kim, Yong Geon;Ji, Seung Woo;Koo, Boncheol;Chang, Byung Uck;Kim, Kwang Pyo
    • Journal of Radiation Protection and Research
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    • v.41 no.3
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    • pp.291-300
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    • 2016
  • Background: It is necessary to assess radiation dose to workers due to inhalation of airborne particulates containing naturally occurring radioactive materials (NORM) to ensure radiological safety required by the Natural Radiation Safety Management Act. The objective of this study is to develop an internal dose assessment procedure for workers at industries using raw materials containing natural radionuclides. Materials and Methods: The dose assessment procedure was developed based on harmonization, accuracy, and proportionality. The procedure includes determination of dose assessment necessity, preliminary dose estimation, airborne particulate sampling and characterization, and detailed assessment of radiation dose. Results and Discussion: The developed dose assessment procedure is as follows. Radioactivity concentration criteria to determine dose assessment necessity are $10Bq{\cdot}g^{-1}$ for $^{40}K$ and $1Bq{\cdot}g^{-1}$ for the other natural radionuclides. The preliminary dose estimation is performed using annual limit on intake (ALI). The estimated doses are classified into 3 groups ( < 0.1 mSv, 0.1-0.3 mSv, and > 0.3 mSv). Air sampling methods are determined based on the dose estimates. Detailed dose assessment is performed using air sampling and particulate characterization. The final dose results are classified into 4 different levels ( < 0.1 mSv, 0.1-0.3 mSv, 0.3-1 mSv, and > 1 mSv). Proper radiation protection measures are suggested according to the dose level. The developed dose assessment procedure was applied for NORM industries in Korea, including coal combustion, phosphate processing, and monazite handing facilities. Conclusion: The developed procedure provides consistent dose assessment results and contributes to the establishment of optimization of radiological protection in NORM industries.

The development of radiation lifetime measuring module for KAEROT/m2 (KAEROT/m2용 방사선 수명 측정모듈 개발)

  • Lee, Nam-Ho;Kim, Seung-Ho;Kim, Yang-Mo
    • Proceedings of the KIEE Conference
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    • 2003.11c
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    • pp.793-796
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    • 2003
  • The electronics of a mobile robot ill nuclear facilities is required to satisfied the reliability to sustain survival in its radiation environment. To know how much radiation the robot has been encountered to replace sensitive electronic parts, a dosimeter to measure total accumulated dose is necessary. Among many radiation dosimeters or detectors, semiconductor radiation sensors have advantages in terms of power requirements and their sires over conventional detectors. This paper describes the use of the radiation-induced threshold voltage change of a commercial power pMOSFET as an accumulated radiation dose monitoring mean and that of the photo-current of a commercial PIN Diode as a dose-rate measurement mean. Commercial p-type power MOSFETs and PIN Diodes were tested in a Co-60 gamma irradiation facility to see their capabilities as radiation sensors. We found an inexpensive commercial power pMOSFET that shows good linearity in their threshold voltage shift with radiation dose and a PIN diode that shows good linearity in its photo-current change with dose-rate. According to these findings, a radiation hardened hybrid electronic radiation dosimeter for nuclear robots has been developed for the first time. This small hybrid dosimeter has also an advantage in the point of view of reliability improvement by using a diversity concept.

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