• Title/Summary/Keyword: Radiation Database

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Cancer Risk from Medical Radiation Procedures for Coronary Artery Disease: A Nationwide Population-based Cohort Study

  • Hung, Mao-Chin;Hwang, Jeng-Jong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2783-2787
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    • 2013
  • To assess the risk of cancer incidence after medical radiation exposure for coronary artery disease (CAD), a retrospective cohort study was conducted based on Taiwan's National Health Insurance Research Database (NHIRD). Patients with CAD were identified according to the International Classification of Diseases code, 9th Revision, Clinical Modification (ICD-9-CM), and their records of medical radiation procedures were collected from 1997 to 2010. A total of 18,697 subjects with radiation exposure from cardiac imaging or therapeutic procedures for CAD were enrolled, and 19,109 subjects receiving cardiac diagnostic procedures without radiation were adopted as the control group. The distributions of age and gender were similar between the two populations. Cancer risks were evaluated by age-adjusted incidence rate ratio (aIRR) and association with cumulative exposure were further evaluated with relative risks by Poisson regression analysis. A total of 954 and 885 subjects with various types of cancers in both cohorts after following up for over 10 years were found, with incidences of 409.8 and 388.0 per 100,000 person-years, respectively. The risk of breast cancer (aIRR=1.85, 95% confidence interval: 1.14-3.00) was significantly elevated in the exposed female subjects, but no significant cancer risk was found in the exposed males. In addition, cancer risks of the breast and lung were increased with the exposure level. The study suggests that radiation exposure from cardiac imaging or therapeutic procedures for CAD may be associated with the increased risk of breast and lung cancers in CAD patients.

Occupational Radiation Exposure in Korea: 2002 (2002년 국내 방사선 작업종사자의 직업군별 피폭선량)

  • Jeong, Je-Ho;Kwon, Jeong-Wan;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.30 no.4
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    • pp.175-183
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    • 2005
  • Dose distribution of Korean radiation workers classified by occupational categories was analyzed. Statistics of the occupational radiation exposure(ORE) in 2002 of the radiation workers in diagnostic and dental radiology were obtained from the Korea Food and Drug Agency(KFDA) who maintains the database for individual radiation dose records. Corresponding statistics for the rest of radiation workers were obtained by processing the individual annual doses provided by the Korea Radioisotope Association(KRIA) after deletion of individual information. The ORE distribution was classified in term of 28 occupational categories, annual individual dose levels, age groups and gender of 52733 radiation workers as of the year of 2002. The total collective dose was 66.4 man-Sv and resulting average individual ORE was 1.26 mSv. Around 80% of the workers were exposed to minimal doses less than 1.2 mSv. However, it appeared that the recorded doses exceeded 20 mSv for 43 workers in the industrial radiography and for 147 workers in the field of radiology. Particularly, recorded doses of 23 workers in radiology exceeded the annual dose limits of 50 mSv, which is extraordinary when the working environment is considered. It is uncertain whether those doses are real or caused by careless placing of dosimeters in the imaging rooms while the X-ray units are in operation. No one in the workforce of 16 operating nuclear power plant units was exposed over 20 mSv in 2002. Number of workers was the largest in their 30's of age and the mean individual dose was the highest in their 20's. Women were around 20% of the radiation workers and their average dose was around one half of that of man workers.

Proteomics of Protein Expression Profiling in Tissues with Different Radiosensitivity (Proteomics를 이용한 마우스 조직에서의 방사선 감수성 조절 단백질의 탐색)

  • An, Jeung-Hee;Kim, Ji-Young;Seong, Jin-Sil
    • Radiation Oncology Journal
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    • v.22 no.4
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    • pp.298-306
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    • 2004
  • Purpose: The purpose of this study was to identify Radiosensitivity of proteins in tissues with different radiosensitivity. Materials and Methods: C3H/HeJ mice were exposed to 10 Gy. The mice were sacrifiud 8 hrs after radiation. Their spleen and liver tissues were collected and analyzed histologicaly for apoptosis. The expressions of radiosusceptibillty protein were analyzed by 2-dimensional electrophoresis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Resilts: The Peak of apoptosis levels were $35.3{\pm}1.7{\%}$ in spleen and $0.6{\pm}0.2{\%}$ in liver at 8 hrs after radiation. Liver, radioresistant tissues, showed that the levels of ROS metabolism related to proteins such as cytochromm c, glutathione S transferase, NADH dehydrogenase, riken cDNA and peroxiredoxin Vl increased after radiation. The expression of cytochrome c increased significantly in spleen and liver tissues after radiation. In spleen, radiosensitivity tissue, the identified proteins showed a significantly quantitative alteration following radiation. It was categorized as signal transduction, apoptosis, cytokine, Ca signal related protein, stress-related protein, cytoskeletal regulation, ROS metabolism, and others. Conclusion: Differences of radiation-induced apoptosis by tissues specifted were coupled with the induction of related radiosensitivity and radioresistant proteins. The result suggests that apoptosis relate protein and redox proteins play important roles in this radiosusceptibility.

Development of solar radiation forecasting system using clod cover information (운량 정보를 활용한 일사량 예측시스템의 개발)

  • Yun, ChangYeol;Jo, Dokki;Kim, GwangDeuk;Kang, YongHeack
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.11a
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    • pp.131-131
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    • 2011
  • 태양광 및 태양열 설비의 효율적인 관리를 위해서는 관련 일사정보가 사전정보로 제공되어 시스템 운용을 위한 입력인자로 활용되어야 한다. 특히 전력그리드에 연계되어 설비가 활용된다고 하면, 그 에너지 공급이 불규칙적인 신재생에너지원의 특성으로 인해 에너지 공급량의 예측이 선행되어 기존의 전력공급체계가 이를 지원할 수 있는 모델과 시스템이 구비되어야 한다. 기존의 다양한 연구들이 한정된 국소지점에 대해 다양한 예측기법을 적용하여 평가를 실시하였지만, 장기간의 결과 축적이 이루어지지 못해 그 신뢰성 확보에 어려움을 겪고 있다. 본 연구에서는 현재 한국에너지기술연구원에서 관리되는 일사정보를 활용하여 청명한 날의 표준 일사 데이터베이스를 생성하고, 기상청에서 RSS(Rich Site Summary) 형태로 지원하는 운량정보를 이용하여 3시간 이상의 미래정보를 계속적으로 산출할 수 있는 시스템을 제작하고자 하였다.

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A Patterns of Care Study of the Various Radiation Therapies for Prostate Cancer among Korean Radiation Oncologists in 2006 (Patterns of Care Study를 위한 2006년 한국 방사선종양학과 전문의들의 전립선암 방사선치료원칙 조사연구)

  • Kim, Jin-Hee;Kim, Jae-Sung;Ha, Sung-Whan;Shin, Seong-Soo;Park, Won;Cho, Jae-Ho;Suh, Chang-Ok;Oh, Young-Taek;Shin, Sei-Won;Kim, Jae-Chul;Jang, Ji-Young;Nam, Taek-Keun;Choi, Young-Min;Kim, Il-Han
    • Radiation Oncology Journal
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    • v.26 no.2
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    • pp.96-103
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    • 2008
  • Purpose: To conduct a nationwide academic hospital patterns of the practice status and principles of radiotherapy for prostate cancer. The survey will help develop the framework of a database of Korean in Patterns of Case Study. Materials and Methods: A questionnaire about radiation treatment status and principles was sent to radiation oncologists in charge of prostate cancer treatment at thirteen academic hospitals in Korea. The data was analyzed to find treatment principles among the radiation oncologists when treating prostate cancer. Results: The number of patients with prostate cancer and treated with radiation ranged from 60 to 150 per academic hospital in Seoul City and 10 to 15 outside of Seoul City in 2006. The primary diagnostic methods of prostate cancer included the ultrasound guided biopsy on 6 to 12 prostate sites(mean=9), followed by magnetic resonance imaging and a whole body bone scan. Internal and external immobilizations were used in 61.5% and 76.9%, respectively, with diverse radiation targets. Whole pelvis radiation therapy(dose ranging from 45.0 to 50.4 Gy) was performed in 76.9%, followed by the irradiation of seminal vesicles($54.0{\sim}73.8$ Gy) in 92.3%. The definitive radiotherapy doses were increased as a function of risk group, but the range of radiation doses was wide(60.0 to 78.5 Gy). Intensity modulated radiation therapy using doses greater than 70 Gy, were performed in 53.8% of academic hospitals. In addition, the simultaneous intra-factional boost(SIB) technique was used in three hospitals; however, the target volume and radiation dose were diverse. Radiation therapy to biochemical recurrence after a radical prostatectomy was performed in 84.6%; however, the radiation dose was variable and the radiation field ranged from whole pelvis to prostate bed. Conclusion: The results of this study suggest that a nationwide Korean Patterns of Care Study is necessary for the recommendation of radiation therapy guidelines of prostate cancer.

Validation of MCS code for shielding calculation using SINBAD

  • Feng, XiaoYong;Zhang, Peng;Lee, Hyunsuk;Lee, Deokjung;Lee, Hyun Chul
    • Nuclear Engineering and Technology
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    • v.54 no.9
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    • pp.3429-3439
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    • 2022
  • The MCS code is a computer code developed by the Ulsan National Institute of Science and Technology (UNIST) for simulation and calculation of nuclear reactor systems based on the Monte Carlo method. The code is currently used to solve two main types of reactor physics problems, namely, criticality problems and radiation shielding problems. In this paper, the radiation shielding capability of the MCS code is validated by simulating some selected SINBAD (Shielding Integral Benchmark Archive and Database) experiments. The whole validation was performed in two ways. Firstly, the functionality and computational rationality of the MCS code was verified by comparing the simulation results with those of MCNP code. Secondly, the validity and computational accuracy of the MCS code was confirmed by comparing the simulation results with the experimental results of SINBAD. The simulation results of the MCS code are highly consistent with the those of the MCNP code, and they are within the 2σ error bound of the experiment results. It shows that the calculation results of the MCS code are reliable when simulating the radiation shielding problems.

Gamma ray exposure buildup factor and shielding features for some binary alloys using MCNP-5 simulation code

  • Rammah, Y.S.;Mahmoud, K.A.;Mohammed, Faras Q.;Sayyed, M.I.;Tashlykov, O.L.;El-Mallawany, R.
    • Nuclear Engineering and Technology
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    • v.53 no.8
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    • pp.2661-2668
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    • 2021
  • Gamma radiation shielding features for three series of binary alloys identified as (Pb-Sn), (Pb-Zn), and (Zn-Sn) have been investigated. The mass attenuation coefficients (µ/ρ) for the selected alloys were simulated using the MCNP-5 code in the energy range between 0.01 and 15 MeV. Moreover, the (µ/ρ) values were computed using WinXCOM database in the same energy range to validate the simulation results. Results reveal a good agreement between the simulated and computed values. The half value layer (HVL), mean free path (MFP), effective atomic number (Zeff) and exposure buildup factor (EBF) were evaluated for the selected binary alloys. Results showed that the PS1, PZ1, and ZS2 alloys have the best shielding parameters and better than the commercially standard and available radiation shielding materials. Therefore, the investigated alloys can be used as effective radiation shielding materials against gamma ray with energies between 0.01 and 15 MeV.

Establishing a pre-mining baseline of natural radionuclides distribution and radiation hazard for the Bled El-Hadba sedimentary phosphate deposits (North-Eastern Algeria)

  • S. Benarous;A. Azbouche;B. Boumehdi;S. Chegrouche;N. Atamna;R. Khelifi
    • Nuclear Engineering and Technology
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    • v.54 no.11
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    • pp.4253-4264
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    • 2022
  • Since the implementation of the phosphate project in Bled El-Hadba (BEH) deposit, western region of Tébessa, no detailed study has been conducted to assess the natural radioactivity distribution and the associated radiological risk parameter for this open-pit mine. For the sake of determining a credible premining reference database for the region of interest, 21 samples were collected from different geological layers of the above-mentioned deposit. Gamma Spectrometry was applied for measuring radioactivity using a high resolution HPGe semiconductor detector. The obtained activity results have shown a significant broad variation in the radioactive contents for the different phosphate samples. The total average concentrations (in Bq·kg-1) for 226Ra, 238U, 235U, 232Th and 40K computed for the different type of phosphate layers were found to be 570 ± 169, 788 ± 280, 52 ± 18, 66 ± 6 and 81 ± 18 respectively. The mean activity concentrations of the measured radionuclides were compared to other regional and worldwide deposits. The ratios between the detected radioisotopes have been calculated for spatial distribution of natural radionuclides in the study area. Based on the aforementioned activity concentrations, the corresponding radiation hazard parameters were assessed. Correlations between the obtained parameters were drawn and a multivariate statistical analysis (Pearson Correlation, Cluster and Factor analysis) was carried out in order to identify the existing relationships.

Current Status of SCI & SCIE Publications in the Field of Radiation Oncology in Korea (한국의 방사선종양학과의 SCI 및 SCIE 논문 발표 현황 - 1990년부터 2006년까지)

  • Kang, Jin-Oh
    • Radiation Oncology Journal
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    • v.25 no.1
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    • pp.1-6
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    • 2007
  • [ $\underline{Purpose}$ ]: To investigate current status of SCI (Science Citation Index) and SCI Expanded publications of Korean radiation oncologists. $\underline{Materials\;and\;Methods}$: Published SCI and SCIE articles the conditions of first author's address as "Korea" and "Radiation Oncology" or "Therapeutic Radiology" were searched from Pubmed database. $\underline{Results}$: From 1990 to 2006, 146 SCI articles and 32 SCIE articles were published. Most frequently published journal was International Journal of Radiation Oncology Biology Physics, where 56 articles were found. Articles with 30 or more citations were only five and 10 or more citations were 26. Yonsei University, which had 57 published articles, was the top among 19 affiliations which had one or more SCI and SCIE articles. Authors with five or more articles were 9 and Seong J. of Yonsei University was the top with 19 articles. $\underline{Conclusion}$: The investigations showed disappointing results. The members of Korean Society of Radiation Oncologists must consider a strategy to increase SCI and SCIE publications.

The Development of spatiotemporal database for solar radiation data Management (일사량 에너지 관리를 위한 시공간 DB 구축)

  • 김광득;안상규;고영훈;김순환;안윤혜
    • Proceedings of the Korea Society for Energy Engineering kosee Conference
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    • 2002.05a
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    • pp.49-55
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    • 2002
  • 세계적으로 환경 및 에너지 문제 해결을 위한 대응방안으로 다양한 대체에너지원에 대한 연구와 관련 기술을 중점적으로 개발하고 있다. 또한, 인터넷의 보급으로 인해 그동안 축적된 정보들을 다양한 형태의 지식으로 웹에 서비스하고 있다. 그러나, 현재 국내에서는 기상 정보나 교통 정보와 관련된 단순 정보만을 제공하고 있는 수준이며, 대체에너지원에 대한 정보를 데이터베이스화하여 서비스 제공을 하지 못하는 실정이다.(중략)

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