• 제목/요약/키워드: Radiation Benefit

검색결과 151건 처리시간 0.023초

Survival in Head and Neck Cancers - Results of A Multi-Institution Study

  • Nandakumar, Ambakumar
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.1745-1754
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    • 2016
  • Background: The prime output of Hospital Based Cancer Registries is stage and treatment based survival to evaluate patient care, but because of challenges of obtaining follow-up details a separate study on Patterns of Care and Survival for selected sites was initiated under the National Cancer Registry Programme of India. The results of stage and treatment based survival for head and neck cancers by individual organ sites are presented. Materials and Methods: A standardized Patient Information Form recorded the details and entered on-line at www.hbccrindia.org to a central repository - National Centre for Disease Informatics and Research. Cases from 12 institutions diagnosed between 1 January 2006 and 31 December 2008 comprised the study subjects. The patterns of treatment were examined for 14053 and survival for 4773 patients from five institutions who reported at least 70% follow-up as of 31 December 2012. Results: Surgical treatment with radiation for cancer tongue and mouth showed five year cumulative survival (FCS) of 67.5% and 60.4% respectively for locally advanced stage. Chemo-radiation compared to radiation alone showed better survival benefit of around 15% in both oro and hypo-pharyngeal cancers and their FCS was 40.0%; Hazard Ratio (HR):1.5;CI=1.2-1.9) and 38.7%; (HR):1.7; CI=1.3-2.2). Conclusions: The awareness about the requirement of concurrent chemo-radiation in specifically cancers of the oro and hypopharynx has to be promoted in developing countries. The annual (2014) estimate number of new Head and Neck cancers with locally advanced disease in India is around 140,000 and 91,000 (65%) patients do not receive the benefit of optimal treatment with ensuing poorer survival.

주차장·옥상 유휴부지를 활용한 태양광발전 비용편익 분석: 환경·사회 편익 중심으로 (Analyzing of Solar Power Generation Cost-Benefit Using Idle Sites(Parking Lot & Rooftop): Focusing on Environmental Benefit and Social Benefit)

  • 고형도;김정인;안경진
    • 아태비즈니스연구
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    • 제13권2호
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    • pp.139-154
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    • 2022
  • Purpose - This study aims to analyzing of solar power generation cost-benefit. Design/methodology/approach - We analyzed whether there is economic feasibility by selecting parking lots and idle sites located in four areas of Seoul, Gyeonggi, Chungcheong, Jeolla, and Gyeongsang areas nationwide, and analyzing site conditions and installation capacity. Findings - According to the results of the analysis, it was found that there is low profitability in Seoul, Gyeonggi and Chungcheong regions, where the solar radiation was not excellent even if REC is selected through the contract market. However, it is necessary to analyzed the economical validity the profitable validity including environmental benefits (greenhouse gas reduction, NOx, SOx reduction effect) and social benefits (renewable power supply) that is analyzed by income and operating costs which is occurred from electricity sales and REC sales when installing solar power generation facilities. Research implications or Originality - In this study, economic feasibility was evaluated additionally in consideration of environmental and social benefits. In conclusion, it was shown that businesses are not economical when considering only simple financial aspects are also sufficiently economical when it is considering environmental and social benefits.

대학생들의 방사선 위험 인식이 관리와 편익에 미치는 구조적 관계 (Structural Relationship for Recognition of Radiation Risks on Management and Benefits of the University Students)

  • 성열훈;김성수
    • 디지털융복합연구
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    • 제12권2호
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    • pp.431-437
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    • 2014
  • 본 연구는 방사선의 위험 인식이 방사선 관리와 편익에 미치는 구조적 관계를 실증적으로 분석하고자 수행되었다. 충북소재 1개 4년제 대학의 방사선 관련 대학생들을 대상으로 2013년 4월 1일부터 5월 31일까지 자기기입식 설문조사를 통하여 직접 자료를 수집하였다. 분석결과 방사선 위험 인식이 높을수록 방선선 관리에 대한 인식이 높은 것으로 나타났으며, 이는 편익에 유의한 영향을 미치는 것으로 나타났다. 비록 방사선 위험 인식이 방사선 편익에 직접적인 영향을 미치지는 못하였으나 방사선 관리라는 매개변수를 통해 방사선의 편익에 대한 긍정적 인식이 높아짐을 시사한다. 따라서 방사선의 원활한 활용과 편익을 높이기 위해서는 적절한 방사선 관리의 필요성을 강조하는 교육이 실행되어야 할 것이다.

Radiotherapy for Ovarian Cancers - Redefining the Role

  • Rai, Bhavana;Bansal, Anshuma;Patel, Firuza Darius;Sharma, Suresh Chander
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권12호
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    • pp.4759-4763
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    • 2014
  • Radiation therapy in ovarian cancers has been considered an outdated concept for many years, mainly due to its toxicity and failure to show benefit in terms of survival. Chemotherapy has been extensively used after surgery for these cancers and it has almost replaced radiation therapy as an adjuvant treatment. Nevertheless, failures in ovarian cancers continue to occur even with the use of newer and effective chemotherapy regimens. About 70% patients demonstrate recurrence in the abdomen or pelvis after first line chemotherapy in ovarian cancers. With advances in technology and sophistication of radiation techniques, along with the molecular and biological knowledge of distinct histological subtypes, there is a need to redefine the role of radiation therapy. This review article focuses on the literature on use of radiation in ovarian cancers and its rationale and indications in the present day. For this, a literature pub med/medline search was performed from January 1975 to March 2014 to redefine the role of radiotherapy in ovarian cancers.

치과 X선발생장치 및 방어에 관한 조사연구 (A LIMITED SURVEY OF DENTAL X-RAY UNITS AND PROTECTION IN KOREA)

  • 박태원
    • 치과방사선
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    • 제10권1호
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    • pp.57-61
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    • 1980
  • In dental roentgenograph it is of mutual benefit to the patient and the dentist to use the minimum amount of radiation capable of producing roentgenograms with maximum interprtive informations. Recent increases in the number of diagnostic x-ray examinations made in this country have caused attention to be paid to the quantity of radiation delivered to the population and operator. The purposes of this study was to assess the quality of dental x-ray units, the amount of films, the average processing procedures and the radiation protection methods in korea. The results were as following: 1. Most of radiation generating system were used in low voltage such as 60Kvp, 10㎃. 2. High sensitivity films such as 'D' group of Kodak or Rinn were mainly used and average 14.7 films used per weeks. 3. Some dentists practiced visual processing technic in simple dark room, and others used instant films. 4. 68.26% of patient held the film themselves, but 27.30% were assisted by dentists film holding. 5. In radiation protection method, 7.85% of dentists had protection equipments such as protective barrier, 2.73% wore protective apron, 27.9% made it a rules to avoid beam, and 7.51% used to maintain a distance from the radiation source.

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후두암 환자에서 경구강 레이저 성문절제술 후 음성 복원 수술 (Phonosurgery after Transoral LASER cordectomy in Laryngeal Cancer Patients)

  • 조재근;손영익
    • 대한후두음성언어의학회지
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    • 제24권2호
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    • pp.102-106
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    • 2013
  • The cure rates for early stage laryngeal cancer are similar between laser cordectomy and radiation therapy. As well as the survival outcome, one of the main measures of success in treatment of early laryngeal cancer is voice outcome. Many studies have demonstrated that laser cordectomy and radiation therapy to be equivalent with regard to vocal outcome, whereas others favor radiation. Although such as somewhat disadvantages of voice outcome, laser cordectomy still remains a valid option. Since the patients who treated with laser may benefit from additional phonosurgery to improve postoperative vocal outcome. In this article, we reviewed the techniques of phonosurgery which can be used for laryngeal reconstruction after laser cordectomy. The indications for using each technique are discussed, with particular attention paid to functional outcomes following these reconstructive efforts.

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Applicability of abrasive waterjet cutting to irradiated graphite decommissioning

  • Francesco Perotti ;Eros Mossini ;Elena Macerata;Massimiliano Annoni ;Michele Monno
    • Nuclear Engineering and Technology
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    • 제55권7호
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    • pp.2356-2365
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    • 2023
  • Characterization, dismantling and pre-disposal management of irradiated graphite (i-graphite) have an important role in safe decommissioning of several nuclear facilities which used this material as moderator and reflector. In addition to common radiation protection issues, easily volatizing long-lived radionuclides and stored Wigner energy could be released during imprudent retrieval and processing of i-graphite. With this regard, among all cutting technologies, abrasive waterjet (AWJ) can successfully achieve all of the thermo-mechanical and radiation protection objectives. In this work, factorial experiments were designed and systematically conducted to characterize the AWJ processing parameters and the machining capability. Moreover, the limitation of dust production and secondary waste generation has been addressed since they are important aspects for radiation protection and radioactive waste management. The promising results obtained on non-irradiated nuclear graphite blocks demonstrate the applicability of AWJ as a valid technology for optimizing the retrieval, storage, and disposal of such radioactive waste. These activities would benefit from the points of view of safety, management, and costs.

난소배세포종(Ovarian Dysgerminoma)의 방사선 치료 (Radiation Therapy of Ovarian Dysgerminoma)

  • 장재천;서창옥;김귀언;박창윤
    • Radiation Oncology Journal
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    • 제1권1호
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    • pp.111-118
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    • 1983
  • To evaluate natural history of ovarian dysgerminoma and role of radiation therapy in treatment of ovarian dysgerminoma, retrospective study was carried out in 5 nonirradiated cases and 20 irradiated cases. Conclusions are as follows: 1. Radiation therapy is essential in treatment of ovarian dysgerminoma. 2. Even in stage 1 a, significant recurrence rate is expected in surgery only group. 3. Even in recurrent cases, if adequate radiotherapy is given in stage 1-3, we can predict near complete curability and in stage 4, we can get considerable benefit. 4. Dysgerminoma beyond stage 2 is highly fatal without radiotherapy. 5. Involved field irradiation including whole abdomen and booster RT on bulky tumor area is sufficient in radiotherapy of stage 1, 2, 3, without paraaortic node involvement. Further mediastinal and supraclavicular irradiation is indicated in stage 4 or stage 1, 2, 3, with paraaortic involvement. 6. If bilateral salphingoophorectomy was done. Elective irradiation is recommended in any condition because preservation of ovarian function is not further needed. 7. In cases of small encapsulated stage 1a, We can delay post op. RT under close observation in order to preserve fertility.

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방사선 사고와 급성 방사선 증후군 (Radiological Accident and Acute Radiation Syndrome)

  • 노형근
    • 대한임상독성학회지
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    • 제9권2호
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    • pp.39-48
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    • 2011
  • In mass casualty situation due to radiological accidents, it is important to start aggressive management with rapid triage decisions. External contamination needs immediate decontamination and internal contamination should be treated with special expertise and equipment to prevent the rapid uptake of radionuclides by target organs. Acute radiation syndrome shows a sequence of events that varies with the severity of the exposure. More severe exposures generally lead to more rapid onset of symptoms and severe clinical findings. After the massive exposure, various systems of the body reflect their severe damages that can lead to death within hours or up to several months. The disease progression has classically been divided into four stages: prodromal, latent, manifest illness, and recovery or death. Three characteristic clusters of symptoms including the hematopoietic syndrome, the gastrointestinal syndrome and the cerebrovascular syndrome are all associated with the acute radiation syndrome. The standard medical management of the patients with a potentially survivable radiation exposure includes good medical, surgical and supportive measures. Specific treatment with cytokines and bone marrow transplantation should be considered. The management of internal contamination is much the same as the treatment of poisoning. The standard decontamination should be applied to reduce uptake, and the chelating agents can be administered to enhance the clearance of radioisotopes. Radioactive iodine ($^{131}I$) as one of the nuclear fission products can increase the incidence of thyroid cancer in children. Potential benefit of potassium iodide prophylaxis is greater especially in neonates, infants and small children.

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Multimodality Treatment for Patients with Node-Positive Prostate Cancer: the Role of Radiation Therapy

  • Ochiai, Satoru;Nomoto, Yoshihito;Kobayashi, Shigeki;Yamashita, Yasufumi;Watanabe, Yui;Toyomasu, Yutaka;Kawamura, Tomoko;Takada, Akinori;II, Noriko;Sakuma, Hajime
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.1625-1630
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    • 2016
  • Prostate cancer is the secondary most frequently diagnosed cancer in the world. Although numerous prospective randomized trial have been conducted to guide the management of patients with localized or locally advanced prostate cancer, few clinical trials targeting node-positive prostate cancer have been reported. Therefore, there are still controversies in the optimal management of node-positive prostate cancer. Recently, efficacy of multimodality treatment, including radiation therapy (RT), for such patients has been reported in several articles. The results indicate potential benefit of RT both in adjuvant therapy after prostatectomy and in definitive therapy for node-positive prostate cancer. The aim in this article was to summarize the current evidence for RT and evaluate the role in multimodality treatment for patients with node-positive prostate cancer.