• 대한약침학회지
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• 제19권3호
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• pp.197-206
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• 2016

Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery's pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written informed consent will be obtained from all participants. The participants will receive acupuncture once at ST36 on both sides. The radial arterial pulse waves will be measured on the left arm of the subjects by using an applicable pulse tonometric device (KIOM-PAS). On the right arm (appearing twice), electrocardiogram (ECG), photoplethysmogram (PPG), respiration and cardiac output (CO) signals, will be measured using a physiological data acquisition system (Biopac module), while the velocity of blood flow, and the diameter and the depth of the blood vessel will be measured using an ultrasonogram machine on the right arm (appearing twice). All measurements will be conducted before, during, and after acupuncture. The primary outcome will be the spectral energy at high frequencies above 10 Hz ($SE_{10-30Hz}$) calculated from the KIOM-PAS device signal. Secondary outcomes will be various variables obtained from the KIOM-PAS device, ECG, PPG, impedance cardiography modules, and an ultrasonogram machine. Discussion: The results of this trial will provide information regarding the physiological and the hemodynamic mechanisms underlying acupuncture stimulation and clinical evidence for the influence of acupuncture on the pressure pulse wave in the radial artery. Ethics and dissemination: This study was approved by the Institutional Review Board (IRB) of Kyung Hee University's Oriental Medical Center, Seoul, Korea (KOMCIRB-150818-HR-030). The study findings will be published in peer-reviewed journals and presented at national and international conferences. Trial registration number: This trial was registered with the Clinical Research Information Service (CRIS) at the Korea National Institute of Health (NIH), Republic of Korea (KCT0001663), which is a registry in the World Health Organization's (WHO's) Registry Network.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2003년도 제27회 추계학술대회
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• pp.44-44
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• 2003

As a basic measurement tool in the areas of animal models of human disease, gene expression and therapy, and drug discovery and development, small animal PET imaging is being used increasingly. An ideal small animal PET should have high sensitivity and high and uniform resolution across the field of view to achieve high image quality. However, the combination of long narrow pixellated crystal array and small ring diameter of small animal PET leads to the degradation of spatial resolution for the source located at off center. This degradation of resolution can be improved by determining the depth of interaction (DOI) in the crystal and by taking into account the information in sorting the coincident events. Among a number of 001 identification schemes, dual layer phsowich detector has been widely investigated by many research groups due to its practicability and effectiveness on extracting DOI information. However, the effects of each crystal length composing dual layer phoswich detector on DOI measurements and image qualities were not fully characterized. In order to minimize the DOI effect, the length of each layer of phoswich detector should be optimized. The aim of this study was to perform simulations using a simulation tool, GATE to design the optimum lengths of crystals composing a dual layer phoswich detector. The simulated small PET system employed LSO front layer LuYAP back layer phoswich detector modules and the module consisted of 8${\times}$8 arrays of dual layer crystals with 2 mm ${\times}$ 2 mm sensitive area coupled to a Hamamatsu R7600 00 M64 PSPMT. Sensitivities and variation of radial resolutions were simulated by varying the length of LSO front layer from 0 to 10 mm while the total length (LSO + LuYAP) was fixed to 20 mm for 10 cm diameter ring scanner. The radial resolution uniformity was markedly improved by using DOI information. There existed the optimal lengths of crystal layers to minimize the variation of radial resolutions. In 10 cm ring scanner configuration, the radial resolution was kept below 3.4 mm over 8 cm FOV while the sensitivity was higher than 7.4% for LSO 5 mm : LuYAP 15 mm phoswich detector. In this study, the optimal length of dual layer phoswich detector was derived to achieve high and uniform radial resolution.

• Journal of Biosystems Engineering
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• 제26권3호
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• pp.245-252
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• 2001

This study was carried out to investigate the effect of three factors(dynamic load, inflation pressure and multiple passes of the tire) on the contact pressure and the soil stresses under the tire. A series of soil bin experiment was conducted with a 6.00R14 radial-ply tire for sandy loam soil. Tire contact pressure at soil surface and soil stresses at 10cm and 20cm soil depth were measured for the three levels of dynamic load(1.17kN, 2.35kN and 3.53kN), for the three levels of tire inflation pressure(103.42kPa, 206.84kPa and 413.69kPa), and for five different number of passes(1, 2, 3, 4 and 5 pass). The following results were drawn from this study 1) As dynamic load, inflation pressure and number of passes of the tire increased, tire contact pressure at soil surface and soil stresses at 10cm and 20cm soil depth increased accordingly. Thus increased in dynamic load, inflation pressure and number of passes of the tire would increase soil compaction. 2) The effect of three different factors, or dynamic load, inflation pressure and number of passes of the tire, decreased as the soil depth increase. Consequently, it was found that the soil compaction at a shallow depth in soil is larger than that at deep place in soil. 3) The increase of dynamic load and number of passes increased soil stress exponentially, but the increase of inflation pressure increased soil stress linearly. The effect of tire inflation pressure on soil stress was relatively less than that of the dynamic load. Therefore, it was concluded that dynamic load is more important factor affecting soil compaction in comparison to the inflation pressure of tire.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.113-119
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• 2008

In pulse diagnosis, floating pulse and sinking pulse are frequently used for diagnosis about where disease is located and how much severe they are. However, in what mechanism floating pulse and sinking pulse arise is not known well. There are two point of views on substantial of floating pulse and sinking pulse. The first one is the floating and sinking degrees is the expression on the depth of pulsation. And, the second one is floating and sinking pulse is based on the response of pulsation to the indent pressure on radial artery. In this paper, we discussed these two opinions in the view point of tonometric measurement. The process for diagnosis on floating pulse and sinking pulse is similar to the tonometric measurement for non invasive blood pressure or intraocular pressure. We modelled the degrees of depth of pulsation with different indent pressures for initial pulsation feeling and different slopes of indent pressure lines. From this modelling, we can confirm the effect of pulsation depth on P-H curve, that is, in the model where lower pulsation is assumed, the shift of optimal indent pressure to the right was observed. The response of pulse pressure to the indent pressure was tried to be modelled with the degrees of mean blood pressure. Consequently, we tried to model the phenomenon of floating and sinking pulse for the first. And, from this modelling, we can get abundant understanding on how floating and sinking pulse can be caused. In the further study, we want to prove the suitability of this tonometric measurement based modelling with various studies including ultrasound measurement for the depth of pulsation in different EMI subjects.

• Journal of the Korean Wood Science and Technology
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• 제52권1호
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• pp.58-69
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• 2024

To evaluate the adhesive characteristics of mixed cross-laminated timber (CLT) using domestic softwoods structural lumber proposed by KS F 3020 and yellow poplar, penetration depth of adhesive and thickness of bonding line were analyzed based on the results of boiling water soaking delamination. 3 Types of adhesives and 2 types of major layer were divided into a 5 ply CLT using yellow popular as minor layer. The bonding performance of the mixed CLT as structural members was evaluated based on the KS F 2081. The thickness of bonding line between layers of the mixed CLT was measured with a scanning electron microscope, and the adhesive penetration depth in the layer members was measured with an optical microscope. As a result of boiling water soaking delamination test of mixed CLT, the CLT specimens using PRF and PUR adhesives met the requirements of KS F 2081. It was verified that the penetration path of the adhesive in the layes was mainly through the tracheid cell in the case of Japanese larch and Korean red pine layers, and through the vessel and radial tissue in yellow popular layers. The penetration depth of the adhesive was the highest for the PRF adhesive under the same pressing time conditions, and the thickness of the bonding line was in inverse proportion to the penetration depth in the case of the PUR adhesive.

• 한국지리정보학회지
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• 제23권3호
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• pp.85-99
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• 2020

흐르는 물을 저장하여 공업, 농업, 상수도, 수력발전 등의 다양한 이용과 관광자원으로도 활용할 수 있는 저수지는 중요한 사회기반시설중의 하나이다. 그러므로 저수지의 유지관리는 행정 및 기술적 방안들을 동원하여 관리주체별로 정기적으로 수행되며, 저수지의 유지관리를 위해서는 저수지 하상 파악이 우선적이다. 이를 위하여 본 연구에서는 비교적 신뢰가 높은 Echo sounder를 이용한 방류전의 저수지 수심 측량과 방류후의 저수지 지형 측량을 UAV에 의하여 실시하였다. 그리고 수심 측량 자료를 Inverse Distance Weighting 보간, Kriging 보간, Minimum curvature 보간, Radial basis function 보간 등의 공간 보간별로 저수지의 내용적을 산출하여 UAV에 의한 방류 후 내용적 및 단면적을 비교 분석함으로 다음과 같은 결과를 알 수 있었다. 첫째, UAV에 의한 지형 자료와 Echo sounder에 의한 수심 자료를 공간 보간 기법별 적용 결과 Kriging 보간이 약 97%의 저수지 내용적 정확도를 확인 할 수 있었다. 둘째, 저수지 하상의 형상 비교를 위하여 검토 단면 설정 후 지형 선형과 보간별 선형의 상이 면적차를 비교한 결과 Kriging 보간이 최소 단면적 차이를 보임으로 지형 선형과의 가장 유사 형상임을 알 수 있었다. 따라서 Echo sounder에 의해 취득된 수심 자료로 저수지 하상의 최적 모델링 구축시 저수지의 효율적 유지관리에 기초적 자료 제공이 가능하리라 판단된다.

• 한국생산제조학회지
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• 제23권3호
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• pp.284-290
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• 2014

Aluminum alloy is a core material for structural parts of aircraft and automobiles to reduce the weight and maintain high specific strength. This study evaluates the machinability and investigates the optimal cutting conditions considering the surface integrity and productivity for Al7050-T7451 milling. The machining variables considered are the feed per tooth, spindle speed, axial depth of the cut, and radial depth of the cut. The machinability evaluation of Al7050-T7451 is conducted by analyzing the cutting force signals, acceleration signals, AE signals, and machined surface conditions. The optimal cutting conditions are determined by analyzing the experimental results using response surface methodology for stable machining considering the productivity and surface integrity.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.379-382
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• 1997

A method for measuring optical properties of biological medium was investigated by using the frequency domain spectroscopy. When amplitude-modulated light with the frequency of several tens up to several hundred MHz propagates through a scattering medium, the phase lag and the amplitude reduction occur. The phase lag depends on the average of optical path lengths. The amplitude reduction with respect to the radial distance is influenced by the penetration depth. The mean of optical path length and penetration depth are related to optical coefficients. The phase lag and the amplitude reduction were measured based on the heterodyne detection method. The experimental data were fitted with the theoretical curves derived from diffusion theory and the absorption and scattering coefficients were calculated.

• Journal of the Optical Society of Korea
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• 제20권1호
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• pp.101-106
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• 2016

A pupil filter is a useful technique for modifying the light intensity distribution near the focus of an optical system to realize depth of field (DOF) extension and superresolution. In this paper, we proposed a new design of the phase only pupil filter by using Zernike polynomials. The effect of design parameters of the new filters on DOF extension and superresolution are discussed, such as defocus Strehl ratio (S.R.), superresolution factor (G) and relative first side lobe intensity (M). In comparison with the other two types of pupil filters, the proposed filter presents its advantages on controlling both the axial and radial light intensity distribution. Finally, defocused imaging simulations are carried out to further demonstrate the effectiveness and superiority of the proposed pupil filter on DOF extension and superresolution in an optical imaging system.

• 동력기계공학회지
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• 제16권4호
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• pp.51-59
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• 2012

The computational flow analysis using LES technique was carried out to investigate the flow characteristics of a sirocco fan under the maximum flowrate condition. The commercial SC/Tetra software was used for this unsteady and three-dimensional numerical analysis. In consequence, because a flow is unstable within the range of about 50% of a housing depth from a bellmouth around the cutoff region, the passing flow through the blade cascade occurred on the X-Y plane is a slow or a reverse with approaching to the housing inlet. Also, the secondary flow shows on the radial plane of a housing, and its vortex center exists within about 33% of a housing depth from a bellmouth except the cutoff region. Moreover, the flow occurring on the exit plane of a sirocco fan shows a complex secondary flow.