• Title/Summary/Keyword: Race Factors

검색결과 148건 처리시간 0.023초

제한된 평균 생존시간을 이용한 위암 3기 자료 분석에 관한 연구 (Analysis of stage III stomach cancer using the restricted mean survival time)

  • 김빛나;이민정
    • 응용통계연구
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    • 제34권2호
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    • pp.255-266
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    • 2021
  • 본 연구는 미국 국립암연구소의 SEER 프로그램에서 제공하는 위암 3기 자료에 대해 항암치료의 효과를 비교하고 위암 생존율에 유의한 영향을 미치는 요인을 알아보고자 한다. 본 연구에서 분석한 위암 3기 자료는 비례위험 가정이 성립하지 않아 대안으로 제한된 평균 생존시간을 이용한 분석 방법을 자료 분석에 적용하였다. 의사-관측들을 이용하여 제한된 평균 생존시간을 추정하였고, 제한된 평균 생존시간 추정량에 기반한 검정통계량을 이용하여 항암치료의 효과를 파악하였다. 일반화 선형모형을 이용한 회귀모형을 통해 위암 3기 환자의 평균 생존시간에 유의한 영향을 미치는 공변량들의 효과를 추정하였다. 항암치료법에 따라 위암 3기 환자의 평균 생존시간에 유의한 차이가 있음을 확인하였고, 진단연령, 인종, 세분화병기, 분화도, 종양의 크기, 수술여부, 항암치료가 위암 3기 환자의 평균 생존시간에 유의한 영향을 미치는 요인들이였으며, 그 중 수술여부가 위암 3기 환자의 평균 생존시간을 늘리는데 가장 큰 영향을 미치는 요인임을 확인하였다.

Associations between Poorer Mental Health with Work-Related Effort, Reward, and Overcommitment among a Sample of Formal US Solid Waste Workers during the COVID-19 Pandemic

  • Abas Shkembi;Aurora B. Le;Richard L. Neitzel
    • Safety and Health at Work
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    • 제14권1호
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    • pp.93-99
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    • 2023
  • Background: Effort-reward imbalance (ERI) and overcommitment at work have been associated poorer mental health. However, nonlinear and nonadditive effects have not been investigated previously. Methods: The association between effort, reward, and overcommitment with odds of poorer mental health was examined among a sample of 68 formal United States waste workers (87% male). Traditional, logistic regression and Bayesian Kernel machine regression (BKMR) modeling was conducted. Models controlled for age, education level, race, gender, union status, and physical health status. Results: The traditional, logistic regression found only overcommitment was significantly associated with poorer mental health (IQR increase: OR = 6.7; 95% CI: 1.7 to 25.5) when controlling for effort and reward (or ERI alone). Results from the BKMR showed that a simultaneous IQR increase in higher effort, lower reward, and higher overcommitment was associated with 6.6 (95% CI: 1.7 to 33.4) times significantly higher odds of poorer mental health. An IQR increase in overcommitment was associated with 5.6 (95% CI: 1.6 to 24.9) times significantly higher odds of poorer mental health when controlling for effort and reward. Higher effort and lower reward at work may not always be associated with poorer mental health but rather they may have an inverse, U-shaped relationship with mental health. No interaction between effort, reward, or overcommitment was observed. Conclusion: When taking into the consideration the relationship between effort, reward, and overcommitment, overcommitment may be most indicative of poorer mental health. Organizations should assess their workers' perceptions of overcommitment to target potential areas of improvement to enhance mental health outcomes.

패싱, 경계와 차이의 서사 -제임스 W. 존슨과 넬라 라선 (Boundaries and Differences in the Narrative of Passing: James W. Johnson and Nella Larsen)

  • 강희
    • 영어영문학
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    • 제53권2호
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    • pp.307-333
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    • 2007
  • When W. E. B. Du Bois says that "the problem of the twentieth century is the problem of the color line," such a statement clearly recognizes the significance of the issue of racial identity, a cultural phenomenon called 'passing.' Both Johnson in The Autobiography of an Ex-Colored Man and Larsen in Passing confront this issue. Both novels, using the metaphor of passing, not only trace the racial anxiety and race politics of the time but also expose the unstable landscape of the established social and cultural boundaries of racial identity. Mapping out multiple meanings and various dimensions of passing, this paper argues how Johnson's and Larsen's narratives display the ambivalence of color line while they at the same time complicate, problematize, and destabilize the mainstream racial boundaries and differences. It furthers to delineate how the two writers, with difference, deal with the problem of passing, the significance of racial identity, and black middle class values along with its intraracial differences. Rather than draw a clear definition of and a definitive closure on passing narrative, this paper focuses on its complexities and undecidability, challenging every dimension of its established significations. It also explores the complex dynamic between passing act and individual identity, for passing here is not just a racially signified term but extends its significance to the other factors of identity, such as class and even sexuality. Johnson and Larsen open up a site for a newly emergent, modern racial identity for black middle class in the twentieth century American urban spaces. Both writers, illuminating the subversive and slippery nature of language in their passing narrative, clearly herald new, different forms of Afro-American writings and themes for the different century they face.

코로나19의 행동생태학: 안면 매력 인식과 혐오 반응의 복합적 상호작용 (Behavioral Ecology of COVID-19: Complex Interactions Between Facial Attractiveness Perception and Disgust Reactions)

  • 손경배;박한선
    • 정신신체의학
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    • 제32권1호
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    • pp.10-23
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    • 2024
  • 본 연구는 코로나19 팬데믹 동안 마스크 착용자에 대한 매력도와 사회적 인식 변화를 고찰한다. 코로나19 이전에는 마스크가 감염 신호로 여겨져 매력도를 감소시켰으나, 팬데믹 이후 마스크 착용이 일상화되면서 인식 메커니즘이 복잡해졌다. 마스크 착용자에 대한 매력도와 사회적 인식은 착용자의 기본 매력도, 인종, 마스크에 대한 인식 등에 따라 달라진다. 이로 인해 연구 결과가 일관되지 않다. 이는 실험 방법의 불일치와 피험자 개인차를 고려하지 못한 결과다. 정신의학적 관점에서 팬데믹 상황에서의 매력 인식을 연구하기 위해서는 행동면역계와 관련된 심리적 메커니즘을 중심으로 새로운 가설을 수립하고 검증해야 한다. 이는 대인 지각과 혐오가 정신건강에 미치는 영향을 이해하는 데 중요한 단서를 제공할 수 있다.

Incidence of Low Seroimmunity to Hepatitis B Virus in Children with Inflammatory Bowel Disease: A Single Center Experience

  • Hala H. Mansour ;Ayman E. Eskander;Sara M. Osman;Normeen H. Rady
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제27권2호
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    • pp.104-112
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    • 2024
  • Purpose: Immunosuppressive therapy is frequently administered to patients with inflammatory bowel disease (IBD), which may make them more susceptible to infections like hepatitis B. Methods: A cross-sectional study was conducted on patients aged 5-18 years diagnosed with IBD who visited a gastroenterology clinic along with controls who were the same age as the patients with IBD and were healthy overall. A logistic regression analysis using the independent variables of age, sex, race, disease phenotype, surgery, and medications and the dependent variable of adequate hepatitis B surface antibody (HBsAb) titers (>10 mIU/mL) was performed on quantitative serum HBsAb titers. Results: The study enrolled 62 patients, including 37 males and 25 females. Crohn's disease, ulcerative colitis, and indeterminate colitis were diagnosed in 16, 22, and 24 patients, respectively. Thirty-nine patients were taking corticosteroids at the time of the study, 42 were taking immunomodulators, and four were taking biologics. Compared to 44.7% of the control group, 9.3% of the patients had protective titers. Only 12 out of 62 patients had HBsAb titers greater than 10 million IU/mL. None of the patients who received biologics or corticosteroids and 3.2% of those who received immunomodulators were found to be seroimmuned. Conclusion: The younger patients had the highest titers. Patient-specific factors that may impact these low titers include the length of the patient's illness and the use of immunosuppressants.

Ongoing Clinical Trials of Vaccines to Fight against COVID-19 Pandemic

  • Chiranjib Chakraborty;Ashish Ranjan Sharma;Manojit Bhattacharya;Garima Sharma;Rudra P. Saha;Sang-Soo Lee
    • IMMUNE NETWORK
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    • 제21권1호
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    • pp.5.1-5.22
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    • 2021
  • Coronavirus disease 2019 (COVID-19) has developed as a pandemic, and it created an outrageous effect on the current healthcare and economic system throughout the globe. To date, there is no appropriate therapeutics or vaccines against the disease. The entire human race is eagerly waiting for the development of new therapeutics or vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Efforts are being taken to develop vaccines at a rapid rate for fighting against the ongoing pandemic situation. Amongst the various vaccines under consideration, some are either in the preclinical stage or in the clinical stages of development (phase-I, -II, and -III). Even, phase-III trials are being conducted for some repurposed vaccines like Bacillus Calmette-Guérin, polio vaccine, and measles-mumps-rubella. We have highlighted the ongoing clinical trial landscape of the COVID-19 as well as repurposed vaccines. An insight into the current status of the available antigenic epitopes for SARS-CoV-2 and different types of vaccine platforms of COVID-19 vaccines has been discussed. These vaccines are highlighted throughout the world by different news agencies. Moreover, ongoing clinical trials for repurposed vaccines for COVID-19 and critical factors associated with the development of COVID-19 vaccines have also been described.

중국 소수민족의 복식 연구(1) (The costume culture of China is as old and varied as her long history)

  • 박춘순
    • 복식
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    • 제26권
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    • pp.175-206
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    • 1995
  • The costume culture of China is as old and varied as her long history. As China is a multiracial nation and consists of fifty-six min-ority races including Han race, there are not only fifty-six different costumes in China but each races' costume habit is very different. Therefore, Chinese penninsula can be considered an enor-mous exhibition center of the costumes. This study undertook on the assumption that the costumes' mainstream of Korea and east-northern Asia as well as that of China could be examined by investigating the minority races' costumes in the east-and west-northern areas of China. The process of evolution of the costume of a particular people, country or area is subject not only to constraints related to geography such as climate, topography or local products but is also affected by numorous environmental influences including cultural, economic, social and even pol-itical ones in terms of the selection of material, styling, color and standard of tailoring. In other words, things like philosophy of life, religious be-lief, aesthetic outlook, moral code, class system, degree of affluence, and cultural exchange will all be reflected directly or indirectly by features of a people's or country's style costume. Of course, there are several factors affecting to the style of costume of the minority people in China. However, the only three factors-geo-graphical and environmental, production method, and religious belef-will be touched in this study. First of all, the geograghical and eenviron-mental factor would be the decisive one because the costume should be designed to overcome the constraints of climate and geographical environ-ments. Accordingly, each race has an unique style of costume. The costume of the minority races in the northern parts are loose and wide, and made of warm furs. For instance, Mongolian robe has the quality of anti-wind, anti-cold and warmness, and the width of a sleeve is narrow and long. Secondly, the costume style can be said to be limited by the production pattern, when the geo-graphical environment was affected to decide the costume style, the production pattern was together affected to it . In case of Mongolian robe, they should satisfy the dual condition as the practical function. One is the condition that they should be fitted to the climate, and the other is the condition that they should be suit-able to the nomadic life. Mongolian robes are suitable to the nomadic peoples because they are designed for not only overcoming the cold wind and weather but being used as the bedquit at night. The costumes of Hoche people was made of the skin of the fish and wild animals because of their main means of living being fishing and hunting. Accordingly, their costumes are dur-able, warm and water-proof. Finally, the style of the costume is affected by the religious belief. In other words, the pattern in fashion is closely related with the religious be-lief or ancestor worship and nature worship. Ac-cordingly, the symbols of these worship are often emerged in the decoration of the costume. The design of costume of the people in the northern areas of China is very simple. It is related with their monotheism. On the other hand, the costumes of twen쇼 minority races in the east-northern parts of China can be devided into three racial groups such as the long robes of Man people and Mongols, Tunics of the peoples in the west-northern areas, and the pants and jackets of Hoche people. The minorority races all has not only the unique costume habit but their costumes are also related with their living style and production means.

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테러 확산의 문명 갈등적 요인 : 기독교와 이슬람을 중심으로 (Civilization conflict factors of the spread of Terrorism - Focusing on Islam and Christianity -)

  • 공배완
    • 융합보안논문지
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    • 제13권5호
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    • pp.107-116
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    • 2013
  • 세계의 곳곳에서 발생되고 있는 지역적인 분쟁은 새로운 양상으로 확산되고 있다. 민족과 문명, 종교적 이데올로기를 기반으로 한 지역 패권주의적 경향이 갈등의 요인으로 나타나고 있는 것이다. 이는 대물림되는 특성을 가지고 있으며, 문명 간의 충돌로 확산되고 있다. 특히 기독교권과 이슬람권의 대립과 갈등은 국제정치적 양상으로 표면화 되고 있으며, 인류안보에 위협요소로 다가서고 있다. 기독교 정신의 우월성을 주장하는 서구 신진국의 경우 인류의 구원과 세계평화라는 역사적 사명감을 가지고 비민주성, 인권, 여성의 권리, 저개발, 핵문제 등을 기독교의 정신과 연계하면서 후진문명으로 간주하고, 민주주의와 인권문제를 앞세워 서구식 발전모델을 강요하고 있다. 절대 일신교를 믿는 이슬람은 그 신(神)만을 주님으로 정해 '노예'가 되어 섬기겠다는 결의를 품고 있으며, 종교적 정치적 사회적 및 문화적 성격이 깊이 배어 있고, 지리적으로도 서로 밀접하게 인접하고 있어 집중성을 나타내는 정도가 다른 문명권에 비해 높게 나타나고 있다. 비폭력을 주장하는 이슬람의 교리가 '코란'과 '칼'이라는 폭력적 이미지로 알려지게 된 것은 문화 간 충돌에서 나타나는 무력적인 방법 때문이다. 오늘날 세계가 직면하고 있는 문명의 충돌은 종교적 갈등문제에서 비롯되고 있고, 이는 민족 간의 대립과 마찰로 나타난다. 특히, 기독교와 이슬람의 뿌리 깊은 종교적 대립은 아랍과 이스라엘의 생존권 다툼에서 비롯하여 기독교와 이슬람 간의 대립으로 확대되었다. 문명의 요인에 의한 테러의 발생과 확산은 역사적으로 증명되어 왔고, 현재에도 지구 곳곳에서 발생되고 있는 사실이다. 문명은 민족의 상징이며 종족의 정체성이기 때문이다.

전자책 사용자만족도 영향요인에 대한 단말기유형의 조절효과 (Moderator Effects of e-Book Terminal Type on Factors Influencing Satisfaction of the e-Book User)

  • 김근형;김성인;오성렬
    • 한국콘텐츠학회논문지
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    • 제13권5호
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    • pp.408-419
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    • 2013
  • 전자책단말기 유형은 크게 전용단말기와 범용단말기로 구분된다. 전자책단말기 시장의 경쟁이 격화되고 있지만 전용단말기와 범용단말기가 건전한 경쟁을 하면서 시장에 공존하는 것이 소비자와 기업에게 바람직한 상황이 될 수 있다. 이를 위하여 단말기유형별로 차별화된 전략으로 경쟁력을 확보하고 독자적인 시장을 만들어가는 것이 필요하다. 본 연구에서는 전자책단말기의 하드웨어품질과 소프트웨어품질을 독립변수로, 사용자만족도를 종속변수로, 단말기유형을 조절변수로 설정하여, 사용자만족도에 영향을 미치는 변수들의 영향력 정도가 단말기유형에 따라 어떻게 달라지는지 살펴보았다. 연구결과로서, 첫째 전자책단말기의 하드웨어품질과 소프트웨어품질은 모두 사용자 만족도에 통계적으로 유의한 영향을 미쳤다. 둘째, 전자책단말기의 하드웨어품질이 사용자만족도에 주는 영향력은 단말기유형에 따라 차이가 없지만, 소프트웨어품질이 사용자만족도에 주는 영향력은 단말기유형에 따라 유의한 차이가 있었다. 이러한 결과를 바탕으로, 전용단말기 제공업체는 범용단말기와 차별화된 제품을 내놓기 위하여 전자책뷰어의 품질을 높일 수 있는 전략을 수립할 필요가 있다.

Incidence and Clinical Characteristic of Venous Thromboembolism in Gynecologic Oncology Patients attending King Chulalongkorn Memorial Hospital over a 10 Year Period

  • Oranratanaphan, S;Termrungruanglert, W;Khemapech, N
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권15호
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    • pp.6705-6709
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    • 2015
  • Background: Venous thromboembolisms (VTEs) constitute a group of diseases including deep vein thrombosis (DVT) and pulmonary embolism (PE). They regarded as the second leading cause of death in cancer patients and several studies have confirmed that VTEs have a negative impact on survival and recurrent rate in both ovarian and endometrial cancer cases. The incidence of VTEs differs worldwide and depends on several risk factors including race, underlying disease, lifestyle, body weight, BMI and genetic risk factors. There is heterogeneity of DVT rates between Asian and Western countries. This study was conducted in order to evaluate the character and incidence of VTEs in gynecologic oncology patients in King Chulalongkorn Memorial Hospital over a 10 year period. Materials and Methods: A retrospective chart review was performed with VTEs defined as objective diagnosis of acute DVT or PE with typical symptoms and signs. Diagnoses were approved byan internist and/or confirmed with imaging studies. Data from both outpatient and inpatient sessions of the affected cases from January 2004 to December 2013 were extracted. General characteristics of the patients were collected with details of the diseases, types of cancer, stage, date of diagnosis of cancer, operative data, treatment outcome, progression free survival and overall survival. Results: Thirty cases of VTEs were identified in a total 2,316 gynecologic oncology cases. The incidence of symptomatic VTEs in total gynecologic oncology patients in our institution is 1.295%. The incidence of VTEs in ovarian cancer patients in our institution was 5.9%. Duration for VTE detection ranged from 13 months before diagnosis of cancer to 33 months after diagnosis of cancer. Most of the VTE cases were detected in ovarian cancer patients (60%). The most common cell type was adenocarcinoma (moderately to poorly differentiated) which accounted for 26.7% of the cases. The second most common cell type was clear cell carcinoma with 23.3% of the cases. Thirty percent of VTE cases developed before cancer was diagnosed, 20% were diagnosed at the same time as cancer detection and fifty percent developed after cancer was diagnosed. Median disease free survival of the gynecologic oncology patients with VTE was 7.5 months. Median overall survival (OS) was 12 months. Median progession free survivals of DVT and PE groups were 11.5 and 5.5 months, respectively. OS of DVT and PE was 12.0 and 11.5 months respectively. Conclusions: The incidence of VTE in Asian countries is believed to be lower than in European or Western countries. From our retrospective review, the incidence of VTEs in all types of gynecologic oncology was 1.295%, much lower than reported in the West. The reason for the lower incidence may genetic differences. Another factor is that VTE in this review was symptomatic, which is less than asymptomatic VTE. More than half of VTEs in this study developed in ovarian cancer patients. The results are compatible with earlier reports that among gynecologic malignancies, the incidence of VTE is highest in ovarian cancer.