• Clinical and Experimental Pediatrics
• /
• v.52 no.1
• /
• pp.56-60
• /
• 2009

Purpose : This study aimed to test whether rotavirus-associated necrotizing enterocolitis (RV+NEC) produced different clinical findings or outcomes from those of non-rotavirus necrotizing enterocolitis (RV-NEC). Methods : Eight patients from the RV+NEC group and 22 patients from the RV-NEC group diagnosed with modified Bell stage II or higher NEC were selected for this study. Fecal specimens from all infants were tested for rotavirus infection using a monoclonal antibody-based enzyme immunoassay (EIA). Clinical, radiographic, and clinical outcome data were analyzed retrospectively. Results : RV+NEC infants had a significantly higher birth weight and were born at a significantly higher gestational age ($33.5{\pm}3.3$ weeks vs. $29.3{\pm}4.4$ weeks; P=0.01). There were no differences in the occurrence of thrombocytopenia, mural gas, and pneumoperitoneum between the 2 groups. However, portal vein gas was more common in the RV+NEC group (88% vs. 9%; P<0.01). Neither the incidence of Bell stage III (or higher) NEC nor surgical intervention differed between the two groups. The number of complications and mortality rates were also similar. Conclusion : Rotavirus-associated NEC occurs in infants with a higher birth weight and those born at a greater gestational age. However, the severity of the condition and the resulting outcomes did not differ from those for infants affected by non-rotavirus NEC.

• The Korean Journal of Applied Statistics
• /
• v.31 no.2
• /
• pp.205-216
• /
• 2018

This paper is concerned with volatility computations for high frequency time series. A threshold-asymmetric realized volatility (T-RV) is suggested to capture a leverage effect. The T-RV is compared with various conventional volatility computations including standard realized volatility, GARCH-type volatilities, historical volatility and exponentially weighted moving average volatility. High frequency KOSPI data are analyzed for illustration.

• Proceedings of the Korea Society of Design Studies Conference
• /
• 2001.05a
• /
• pp.142-143
• /
• 2001

• Journal of Cardiovascular Imaging
• /
• v.30 no.1
• /
• pp.50-58
• /
• 2022

BACKGROUND: Little is known regarding right ventricular (RV) remodeling immediately after Tetralogy of Fallot (TOF) repair. We sought to describe myocardial deformation by cardiac magnetic resonance imaging (CMR) after TOF repair and investigate associations between these parameters and early post-operative outcomes. METHODS: Fifteen infants underwent CMR without sedation as part of a prospective pilot study after undergoing complete TOF repair, prior to hospital discharge. RV deformation (strain) was measured using tissue tracking, in addition to RV ejection fraction (EF), volumes, and pulmonary regurgitant fraction. Pearson correlation coefficients were used to determine associations between both strain and CMR measures/clinical outcomes. RESULTS: Most patients were male (11/15, 73%), with median age at TOF repair 53 days (interquartile range, 13,131). Most patients had pulmonary stenosis (vs. atresia) (11/15, 73%) and 7 (47%) received a transannular patch as part of their repair. RV function was overall preserved with mean RV EF of 62% (standard deviation [SD], 9.8). Peak radial and longitudinal strain were overall diminished (mean ± SD, 33.80 ± 18.30% and -15.50 ± 6.40%, respectively). Longer hospital length of stay after TOF repair was associated with worse RV peak radial ventricular strain (correlation coefficient (r), -0.54; p = 0.04). Greater pulmonary regurgitant fraction was associated with shorter time to peak radial RV strain (r = -0.55, p = 0.03). CONCLUSIONS: In this small study, our findings suggest presence of early decrease in RV strain after TOF repair and its association with hospital stay when changes in EF and RV size are not yet apparent.

• Journal of Life Science
• /
• v.15 no.3 s.70
• /
• pp.415-422
• /
• 2005

library of the mutants was prepared by transposon mutagenesis of the Mycobacterium bovis BCG. We screened this library for the resistance to an anti-tuberculosis antibiotic, PA-824. Most of the mutants resistant to the PA-824 were not able to synthesize the coenzyme $F_{420}$ which is normally produced by the wild type M. bovis BCG strains. HPLC analysis of the cellular extract showed that one of those mutants which lost the ability to synthesize $F_{420}$ still produced F0. The insertion site of the transposon in this mutant was determined by an inverse PCR and the transposon was found to be inserted in the Rv2435c open reading frame (ORF). Rv2435c ORF is predicted to encode an 80.3 kDa protein. Rv2435c protein appears to be bound to the cytoplasmic membrane, its N-terminal present in the periplasm and C-terminal in the cytoplasm. The C-terminal portion of this protein is highly homologous with the adenylyl cyclases of both prokaryotes and eukaryotes. There are 15 ORFs which have homology with the class III AC proteins in the genome of the M. tuberculosis and M. bovis. Two of those, Rv1625c and Rv2435c, are highly homologous with the mammalian ACs. We cloned the cytoplasmic domain of the Rv2435c ORF and expressed it with six histidine residues attached on its C-terminal in Escherichia coli to find out if this protein is a genuine AC. Production of that protein in E. coli was proved by purifying the histidine-tagged protein by using the Ni-NTA resin. This protein, however, failed to complement the cya mutation in E. coli, indicating that this protein lacks the AC activity. All of the further attempts to convert this protein to a functional AC by a mutagenesis with UV or hydroxylamine, or construction of several different fusion proteins with Rv1625c failed. It is, therefore, possible that Rv2435c protein might affect the conversion of F0 to $F_{420}$ not by synthesizing cAMP but by some other way.

• Proceedings of the KIEE Conference
• /
• 2007.07a
• /
• pp.610-611
• /
• 2007

본 논문은 EMTP-RV를 이용하여 변압기 여자돌입전류를 모델링하는 방법을 제시하였다. 우선, 변압기 여자돌입전류의 특성을 조사하였다. 그 다음으로, EMTP-RV의 변압기의 모델링 방법을 분석하여 변압기 여자돌입전류 모델링을 위한 적절한 방법을 선택하였다. 마지막으로, 다양한 조건에 대하여 여자돌입전류를 모델링하여 그 방법의 적합성을 증명하였다.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.14 no.6
• /
• pp.1129-1138
• /
• 2019

Since substations are structurally complex due to the concentration of protection coordination facilities with substation facilities for long distance power transmission, it is difficult to design a protection coordination system to minimize the spreading effect of the fault when a fault occurs on transmission line or distribution line. Therefore, in this paper, the bus configuration and the basic logic of protection coordination that have a major influence on the reliability of substation power supply were analyzed, and the substation protection coordination logic to detect internal and external faults was developed based on EMTP-RV. As the basic logic of substation protection coordination, the percent differential protection relay logic for substation internal fault detection and the overload protection relay logic for inference of external failure were modeled. Finally, the 154kV substation including the protection coordination logic was modeled using EMTP-RV, and the effectiveness of the protection coordination design methodology was confirmed through the several fault simulation cases based on EMTP-RV.

• Journal of the Korean Institute of Telematics and Electronics B
• /
• v.33B no.1
• /
• pp.38-48
• /
• 1996

We implemented and evaluated the preformance of a task level pipelined multicomputer "RV860-PIPE(Realtime Vision i860 system using PIPEline)" for computer vision applications. RV860-PIPE is a message-passing MIMD computer having ring interconnection network which is appropriate for vision processing. We designed the node computer of RV860-PIPE using a 64-bit microprocessor to have generality and high processing power for various vision algorithms. Furthermore, to reduce the communication overhead between node computers and between node computer and a frame grabber, we designed dedicated high speed communication channels between them. We showed the practical applicability of the implemented system by evaluting performances of various computer vision applications like edge detection, real-time moving object tracking, and real-time face recognition.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2007.12a
• /
• pp.322-324
• /
• 2007

최근 엘엔지운반선(LNGC)은 선체의 대형화, DFDE디젤엔진탑재, 재액화설비등의 변화와 함께 해상터미널의 역할을 동시에 할 수 있는 LNG-RV(Regasification Vessel)의 출현을 경험하였으며, 이러한 신계념의 선박의 개발개념, 운항방식 등에 대하여 살펴보도록 한다.

• Clinical and Experimental Pediatrics
• /
• v.50 no.11
• /
• pp.1041-1048
• /
• 2007

Not a few patients in children and adolescents are suffering from right ventricular (RV) dysfunction resulting from various conditions such as chronic lung disease, left ventricular dysfunction, pulmonary hypertension, or congenital heart defect. The RV is different from the left ventricle in terms of ventricular morphology, myocardial contractile pattern and special vulnerability to the pressure overload. Right ventricular failure (RVF) can be evaluated in terms of decreased RV contractility, RV volume overload, and/or RV pressure overload. The management for RVF starts from clear understanding of the pathophysiology of RVF. In addition to correction of the underlying disease, management of RVF per se is very important. Meticulous control of volume status, inotropic agents, vasopressors, and pulmonary selective vasodilators are the main tools in the management of RVF. The relative importance of each tool depends on the individual clinical status. Medical assist device and surgery can be considered selectively in case of refractory RVF to optimal medical treatment.