• 제목/요약/키워드: RSM

검색결과 1,233건 처리시간 0.033초

분열효모에서 mRNA Export와 관련된 rgm1 유전자의 유전학적 분석 (Genetic Analysis of Fission Yeast rsm1 Which is Involved in mRNA Export)

  • 강숙희;윤진호
    • 미생물학회지
    • /
    • 제44권2호
    • /
    • pp.98-104
    • /
    • 2008
  • mRNA의 핵에서 세포질로의 이동(mRNA export)에 관여하는 것으로 여겨지는 분열효모 Schizosaccharomyces pombe의 rsm1 유전자의 역할을 알아보기 위해 $kan^{r}$ 유전자를 이용하여 결실돌연변이주(deletion mutant)를 제조하였다. rsm1 유전자는 생장에 필수 유전자는 아니지만, rsm1 결실돌연변이주는 야생형에 비해 생장이 조금 늦고 mRNA export도 약간의 결함을 보였다. rsm1 유전자와 mRNA export의 중요 유전자와의 연관관계를 알아보기 위해, 이중돌연변이주(double mutants)를 제작하여 생장결함 정도와 mRNA export 결함 정도를 조사하였다. 조사한 유전자들 중에서 mex67 또는 npp106 돌연변이 유전자는 rsm1 결실돌연변이 유전자와 함께 존재하면 생장과mRNA export가 더욱 악화되었다. 반면, thp1 돌연변이 유전자는 rsm1 결실돌연변이 유전자와 함께 존재하면 오히려 생장과 mRNA export 정도를 야생형과 유사한 정도로 호전시켰다. 이와 같은 결과들은 rsm1 유전자가 mRNA의 핵에서 세포질로의 이동에 중요한 역할을 담당하고 있음을 시사한다.

Cyclic loading response of footing on multilayered rubber-soil mixtures

  • Tafreshi, S.N. Moghaddas;Darabi, N. Joz;Dawson, A.R.
    • Geomechanics and Engineering
    • /
    • 제14권2호
    • /
    • pp.115-129
    • /
    • 2018
  • This paper presents a set of results of plate load tests that imposed incremental cyclic loading to a sandy soil bed containing multiple layers of granulated rubber-soil mixture (RSM) at large model scale. Loading and unloading cycles were applied with amplitudes incrementally increasing from 140 to 700 kPa in five steps. A thickness of the RSM layer of approximately 0.4 times the footing diameter was found to deliver the minimum total and residual settlements, irrespective of the level of applied cyclic load. Both the total and residual settlements decrease with increase in the number of RSM layers, regardless of the level of applied cyclic load, but the rate of reduction in both settlements reduces with increase in the number of RSM layers. When the thickness of the RSM layer is smaller, or larger, settlements increase and, at large thicknesses may even exceed those of untreated soil. Layers of the RSM reduced the vertical stress transferred through the foundation depth by distributing the load over a wider area. With the inclusion of RSM layers, the coefficient of elastic uniform compression decreases by a factor of around 3-4. A softer response was obtained when more RSM layers were included beneath the footing damping capacity improves appreciably when the sand bed incorporates RSM layers. Numerical modeling using "FLAC-3D" confirms that multiple RSM layers will improve the performance of a foundation under heavy loading.

직접 토크 제어를 이용한 리럭턴스 동기 전동기의 최대 효율제어 (An Optimal Efficiency Control of Reluctance Synchronous Motor using Direct Torque Control)

  • 박홍일;김남훈;최경호;김동희;김민회
    • 전력전자학회:학술대회논문집
    • /
    • 전력전자학회 2002년도 전력전자학술대회 논문집
    • /
    • pp.431-434
    • /
    • 2002
  • This paper presents an implementation of direct torque control(DTC) of Reluctance Synchronous Motor(RSM) with an efficiency optimization using the 32bit DSP TMS320C31. The influence of iron loss can not neglected as high speed and precision torque control of RSM, so the optimal current ration between torque current and exiting current analytically derived to drive RSM at maximum efficiency For RSM, torque dynamics can be maintained even with controlling the flux level because the generated torque is direct]y proportional to the stator current. The experimental results for an RSM are presented to validate the applicability of the proposed method. The developed control system is shown high efficiency features with 1.0Kw RSM having 2.57 ratio of d/q reluctance.

  • PDF

부산 지역 과학 교육 자원 지도를 활용한 체험학습의 환경교육적 효과 (Effects of Outdoor Activities Utilizing Regional Science Education Resource Map (RSM) in Busan)

  • 유선미;김선영
    • 한국환경교육학회지:환경교육
    • /
    • 제24권3호
    • /
    • pp.44-55
    • /
    • 2011
  • This study examined the effects of RSM (Regional Science education resource Map), developed and provided by Busan metropolitan city Office of Education, at high schools in Busan. Two group of students, who were in the same level of achievement as well as other environmental conditions, participated in this study. Twenty nine of students as an experimental group experienced outdoor activities utilizing RSM, while thirty of students as a control group did not participate in any outdoor activities. The results indicated that compared to the control group of students, the experimental group of students represented a significant improvement in students' environmental attitudes, local ecological interest and eco-friendly behavior. The teachers who guided outdoor activities utilizing RSM suggested that RSM needs to be further subdivided by seasons as well as local districts. They also suggested that RSM needs to be linked with a school curriculum.

  • PDF

Taguchi-RSM 통합모델 제시 (The Development of Taguchi and Response Surface Method Combined Model)

  • 이상복;김연수;윤상운
    • 산업공학
    • /
    • 제23권3호
    • /
    • pp.257-263
    • /
    • 2010
  • Taguchi defined a good quality as 'A correspondence of product characteristic's expected value to the objective value satisfying the minimum variance condition.' For his good quality, he suggested Taguchi Method which is called Robust design which is irrelevant to the effect of these noise factors. Taguchi Method which has many success examples and which is used by many manufacturing industry. But Optimal solution of Taguchi Method is one among the experiments which is not optimal area of experiment point. On the other hand, Response Surface Method (RSM) which has advantage to find optimal solution area experiments points by approximate polynomial regression. But Optimal of RSM is depended on initial point and RSM can not use many factors because of a great many experiment. In this paper, we combine the Taguchi Method and the Response Surface Method with each advantage which is called Taguchi-RSM. Taguchi-RSM has two step, first step to find first solution by Taguchi Method, second step to find optimal solution by RSM with initial point as first step solution. We give example using catapults.

Various levels of rapeseed meal in weaning pig diets from weaning to finishing periods

  • Do, Sung Ho;Kim, Byeong Ock;Fang, Lin Hu;You, Dong Hyeon;Hong, Jin su;Kim, Yoo Yong
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제30권9호
    • /
    • pp.1292-1302
    • /
    • 2017
  • Objective: This experiment was conducted to investigate the influence of rapeseed meal (RSM) supplementation in weaning pig diet on growth performance, blood profile, carcass characteristics and economic analysis on weaning to finishing pigs. Methods: A total of 120 cross bred ([Yorkshire${\times}$Landrace]${\times}$Duroc) weaning pigs were allotted to 5 treatments in a randomized complete block design. Each treatment had 4 replications with 6 pigs per pen. Five different levels of RSM (0%, 2%, 4%, 6%, and 8%) were used as dietary treatments. Results: Overall, no treatment showed significant differences in growth performance with increased dietary RSM levels. The concentration of blood urea nitrogen (BUN) decreased as dietary RSM levels increased in 6 weeks (linear response, p<0.01). Total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triiodothyronine, and thyroxine showed no significant differences, neither were there any significant differences in the immune response (IgG and IgA). As the dietary RSM levels of weaning pig diet were increased, no differences were found among dietary treatments upon performing proximate analyses of the pork after finishing. The influence of RSM supplementation on nutrient digestibility and nitrogen retention were not affected by dietary RSM levels either. With increased dietary RSM levels in the weaning pig diet, no differences among dietary treatments were found after performing proximate analyses of the pork's physiochemical properties. In addition, there were no significant differences observed in pork colors, pH levels, and economic benefits. Conclusion: Consequently, this experiment demonstrated that weaning pig's diet containing RSM influenced BUN concentration, but there were no detrimental effects on the growth performance of weaning pigs with up to 8% RSM in the diet.

Effects of Replacing Soybean Meal with Fermented Rapeseed Meal on Performance, Serum Biochemical Variables and Intestinal Morphology of Broilers

  • Xu, F.Z.;Zeng, X.G.;Ding, X.L.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제25권12호
    • /
    • pp.1734-1741
    • /
    • 2012
  • This trial was performed to study the effects of replacing soybean meal (SBM) with fermented rapeseed meal (RSM) on growth performance, serum biochemistry variable and intestinal morphology of broilers. A total of 640 d-old Arbor Acres broiler chicks were randomly allocated to 4 dietary treatments, 4 pens per treatment and 40 birds per pen for a 6-wk feeding trial. In the four treatment groups, fermented RSM replaced soybean meal at 0, 5, 10, and 15%, respectively. On 21 d and 42 d, two birds from each pen were randomly selected and slaughtered. Blood samples and sections of duodenum, jejunum, and ileum were collected for measurement of serum biochemical variables and intestinal morphology, respectively. Results showed that body weight gain (BWG) and feed conversion (FC) were significantly (p<0.01) poorer for birds fed the 15% fermented RSM diet than those fed with 0, 5 and 10% fermented RSM diets during all periods. Compared with 0 and 5% fermented RSM groups, IgG content in the serum of birds in 10 and 15% fermented RSM groups was improved (p<0.01) urea nitrogen content of serum was reduced (p<0.01) during both growing and finishing periods. However, IgM, phosphorus and calcium levels increased (p<0.05) only during the growing period. Increased (p<0.05) villus height was observed in the duodenum and jejunum of broilers fed the diet with 10% fermented RSM. In addition, villus height to crypt depth ratio in the jejunum was significantly higher (p<0.01) for birds fed the diet with 10% fermented RSM than for those fed diets with 0, 5 and 15% fermented RSM. The present results suggest that RSM fermented with Lactobacillus fermentum and Bacillus subtilis is a promising alternative protein source and that it could be safely used replace up to 10% SBM in broiler diets.

FEM을 이용한 영구자석형 릴럭턴스 동기전동기의 자속 장벽 설계에 대한 연구 (A Study on Flux Barrier of Permanent Magnet Assisted Reluctance Synchronous Motor Design using FEM)

  • 김남훈;남상현;최경호
    • 전력전자학회논문지
    • /
    • 제13권4호
    • /
    • pp.295-302
    • /
    • 2008
  • 본 논문에서는 세탁기용으로 사용될 영구자석형 릴럭턴스 동기전동기(permanent-magnet assisted reluctance synchronous motor : PMA-RSM)의 설계와 특성에 대해서 살펴본다. 제안된 PMA-RSM의 특성과 최대 토크 특성을 알아보기 위해서 유한 요소법(finite element method)을 이용 하였다. 저속 구간에서의 충분한 토크를 발생시키기 위해서 회전자의 구조는 릴럭턴스 토크를 만들어내는 돌극 구조와 회전자 내부의 공극에 영구자석을 삽입하는 구조로 구성되어 있다. 전형적인 자속 장벽형(Flux barrier type) 릴럭턴스 동기전동기(RSM : Reluctance Synchronous Motor)와 자속 장벽(Flux barrier)에 자석을 삽입한 경우에 발생되는 현상들에 대해서 비교 분석하고, 또한 제안된 PMA-RSM의 릴럭턴스 토크(reluctance torque)와 자석에 의한 자석 토크(magnetic alignment torque)가 서로 최대가 되는 시점을 시뮬레이션을 통하여 구하며, 그 결과를 이용하여 전동기의 특성, 평균토크 그리고 토크 리플에 대해서 유한 요소법을 통하여 살펴보았다.

WRF, MM5, RSM 모형에서 모의한 2004년 7월 11-18일의 동아시아 몬순의 비교 (Intercomparison of the East-Asian Summer Monsoon on 11-18 July 2004, simulated by WRF, MM5, and RSM models)

  • 함수련;박선주;방철한;정병주;홍성유
    • 대기
    • /
    • 제15권2호
    • /
    • pp.91-99
    • /
    • 2005
  • This study compares the summer monsoon circulations during a heavy rainfall period over the Korean peninsular from 11 to 18 July 2004, simulated by three widely used regional models; WRF, MM5, and RSM. An identical model setup is carried out for all the experiments, except for the physical option differences in the RSM. The three models with a nominal resolution of about 50 km over Korea are nested by NCEP-DOE reanalysis data. Another RSM experiment with the same cumulus parameterization scheme as in the WRF and MM5 is designed to investigate the importance of the representation of subgrid-scale parameterized convection in reproducing monsoonal circulations in East Asia. All thee models are found to be capable of reproducing the general distribution of monsoonal precipitation, extending northeastward from south China across the Korean peninsula, to northern Japan. The results from the WRF and MM5 are similar in terms of accumulated precipitation, but a slightly better performance in the WRF than in the MM5. The RSM improves the bias for precipitation as compared to those from the WRF and MM5, but the pattern correlation is degraded due to overestimation of precipitation in northern China. In the comparison of simulated synoptic scale features, the RSM is found to reproduce the large-scale features well compared to the results from the MM5 and WRF. On the other hand, the simulated precipitation from the RSM with the convection scheme used in the MM5 and WRF is closer to that from the WRF and MM5 simulations, indicating the significant dependency of simulated precipitation in East Asia on the cumulus parameterization scheme.

회화나무꽃 추출물이 함유된 Cosmeceuticals의 제조: Box-Behnken 설계모델을 이용한 최적화 (Preparation of Cosmeceuticals Containing Flos Sophorae Immaturus Extracts: Optimization Using Box-Behnken Design Model)

  • 유봉호;줘청량;이승범
    • 공업화학
    • /
    • 제31권4호
    • /
    • pp.404-410
    • /
    • 2020
  • 본 연구에서는 Box-Behnken 설계모델(BBD-RSM)을 사용하여 회화나무꽃 추출물을 첨가한 cosmeceuticals 유화액의 안정성 조건을 최적화하였다. BBD-RSM의 독립변수로는 유화제의 첨가량, 회화나무꽃 추출물 첨가량, 유화시간, 유화속도 등을 설정하고, 반응치로는 O/W 유화액의 평균액적크기(MDS), 점도 및 유화안정도지수(ESI)를 설정하였다. BBD-RSM 최적화 분석결과 세 가지 반응치를 동시에 부합하는 최적조건은 유화시간(17.8 min), 유화속도(5505 rpm), 유화제의 첨가량(2.28 wt.%), 회화나무꽃 추출물 첨가량(1.05 wt.%)으로 산출되었으며, 이 조건에서의 BBD-RSM 예측결과는 MDS (1875.5 nm), 점도(1789.7 cP), ESI (93.8%)로 얻었다. 또한 이 조건에서 실제 실험을 통해 얻은 결과는 이론 결과에 비래 평균오차율은 5% 이하로 나타났다. 따라서 본 연구에서 BBD-RSM 최적화 분석을 적용할 경우 비교적 높은 유의수준의 만족하는 결과를 얻을 수 있었다.