• 한국식품영양과학회지
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• 제27권6호
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• pp.1183-1188
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• 1998

This study was carried out to elucidate the immunomodulating activity of protein bound polysac charide extracted from Ganoderma lucidum(PSG). Macrophage drived reactive radicals were known as an effector for antimicrobial and anticancer functions. The promising immune response molecule, reactive oxygen intermediates(ROIs), was determined in TIB 71 cells with PSG at various experimental conditions. Treatment with 0.5mg PSG significantly increased the production of ROIs, superoxide anion as well as hydrogen peroxide, from TIB 71 cells(p<0.001). Under the same concentration, con siderable results were obtained from 24 hour cultivation with 106 cells at 5% CO2 incubator. The cells were trigged with PMA(5.3 M) after primed BCG(100 M) or IFN (100U) alone could not induce the production of ROIs, but it had a significant potentiating effect on ROIs secretion when the cells were treated with PSG.

• 한국의학물리학회지:의학물리
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• 제31권4호
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• pp.172-178
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• 2020

Purpose: Radiation oncology information systems (ROIS) have evolved toward connecting and integrating information between radiation treatment procedures. ROIS can play an important role in utilizing modern radiotherapy techniques that have high complexity and require a large amount of information. Methods: Using Access^TM software, we have developed a relational database that is highly optimized for a radiotherapeutic workflow. Results: The prescription table was chosen as the core table to which the other tables were connected, and three types of forms-charts, worklists, and calendars- were suggested. A fast and reliable channel for delivering orders and remarks according to changes in the situation was also designed. Conclusions: We expect our ROIS design to inspire those who need to develop and manage an individual ROIS suitable for their radiation oncology departments at a low cost.

• 정보처리학회논문지D
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• 제11D권3호
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• pp.691-702
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• 2004

본 문은 고속으로 이송되는 컨베이어 벨트 환경에서 획득된 대용량 소포 영상에서 다양한 관심영역(ROI：Region of Interest)을 고속 추출할 수 있는 방법을 제안한다. 제안된 방법의 친 번째 단계에서는 영상을 32${\times}$32 픽셀 크기의 마스크로 나누고 그 중 내부 픽셀의 최대값과 최소값의 차이값이 최저 동적 입계값보다 큰 경우에 1차 후보로 검출한다. 두 번째 단계에서는 1차 후보 마스크를 다시 8${\times}$8크기의 서브마스크로 나누고 적셀 값의 편차(deviation)을 기준으로 최저 임계값보다 큰 마스크만 남김으로서 불필요한 영역을 제거한다. 이러한 전처리 과정을 거쳐 1차원 바코드, 2차원 바코드, 소포의 외형 경계, 레이블 및 문자와 같은 소포의 정보가 기록되어 있는 영역(ROI)을 제외한 나머지 영역을 제거한다. 후처리 과정에서는 위의 ROI 중 2차원 바코드 영역만을 추출하기 위해서 각각의 ROI에 대하여 기준축을 생성한 결과를 이용하여 각각의 영역을 검증하였다. 이와 같은 방법으로 실험한 결과 대용량 소포영상에서 약 200msec 이내에 다양한 ROI를 추출하였으며 100%의 정확도로 2차원 바코드 영역을 지정할 수 있음을 확인하였다.

• 제어로봇시스템학회논문지
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• 제19권3호
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• pp.256-261
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• 2013

In the steel manufacturing area, researches for defect inspection receive a big attention for quality control. This paper proposes an algorithm to detect a scratch defect on steel billets. This algorithm takes ROIs (Regions of Interest), and extracts 11 features which represent properties of defect on a ROI. SVM (Support Vector Machine) is used to classify defect and normal ROIs. The algorithm classifies a frame image of a Billet as a defect image if there is one or more defect ROIs. In the experiments, the proposed algorithm had reliable classifying accuracy.

• ETRI Journal
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• 제28권2호
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• pp.239-242
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• 2006

In this letter, we propose a new functionality to scalable video coding (SVC), that is, the support of multiple region of interests (ROIs) for heterogeneous display resolution. The main objective of SVC is to provide temporal, spatial, and quality scalability of an encoded bitstream. The ROI is an area that is semantically important to a particular user, especially users with heterogeneous display resolutions. Less transmission bandwidth is needed compared to when the entire region is transmitted/decoded and then sub-sampled or cropped. To support multiple ROIs in SVC, we adopt flexible macroblock ordering (FMO), a tool defined in H.264, and based on it, we propose a way to encode and, independently, decode ROIs. The proposed method is implemented on the joint scalable video model (JSVM) and its functionality verified.

• Journal of Magnetics
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• 제22권2호
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• pp.234-237
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• 2017

This study is aimed to optimize a location of region of interest (ROI) in test bolus carotid contrast enhanced magnetic resonance angiography (CE-MRA) at 3.0T. A total of consecutive 270 patients with no cardiovascular and vessel diseases were selected. Patients underwent elliptical centric 3D CE-MRA with the test bolus technique to identify the individual arterial arrival time. Quantitative measurements were performed by drawing ROIs of $25mm^2$ and signal intensities (SI) were measured in the center of common carotid artery (CCA), internal carotid artery (ICA) and aortic arch (AA). As a result, ROIs located within AA showed a significantly clarified arterial peak and over three times increased SI, while no significant arterial peak time differences were observed compared to ROIs located within CCA. In conclusion, it was demonstrated that the aortic arch is the optimal position to locate ROI in test bolus images of the carotid CE-MRA.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.69.3-70
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• 2003

A substantial body of evidence indicates that reactive oxygen intermediates (ROIs) are implicated in pathogenesis of diverse human diseases, including cancer, diabetes and neurodegenerative disorders. Oxidative stress induced by ROIs often causes cell death via apoptosis that is regulated by a plenty of functional genes and their protein products. In the present work, we have investigated the role of bcl-2 in protecting against oxidative death induced by hydrogen peroxide in cultured rat pheochromocytoma (PC12) cells. (omitted)

• Imaging Science in Dentistry
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• 제49권4호
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• pp.295-299
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• 2019

Purpose: This clinical pilot study was performed to determine the effectiveness of dual-energy cone-beam computed tomography (DE-CBCT) in measuring bone mineral density (BMD). Materials and Methods: The BMD values obtained using DE-CBCT were compared to those obtained using calibrated multislice computed tomography (MSCT). After BMD calibration with specially designed phantoms, both DE-CBCT and MSCT scanning were performed in 15 adult dental patients. Three-dimensional (3D) Digital Imaging and Communications in Medicine data were imported into a dental software program, and the defined regions of interest (ROIs) on the 3-dimensional surface-rendered images were identified. The automatically-measured BMD values of the ROIs (g/㎤), the differences in the measured BMD values of the matched ROIs obtained by DE-CBCT and MSCT 3D images, and the correlation between the BMD values obtained by the 2 devices were statistically analyzed. Results: The mean BMD values of the ROIs for the 15 patients as assessed using DE-CBCT and MSCT were 1.09±0.07 g/㎤ and 1.13±0.08 g/㎤, respectively. The mean of the differences between the BMD values of the matched ROIs as assessed using DE-CBCT and calibrated MSCT images was 0.04±0.02 g/㎤. The Pearson correlation coefficient between the BMD values of DE-CBCT and MSCT images was 0.982 (r=0.982, P<0.001). Conclusion: The newly developed DE-CBCT technique could be used to measure jaw BMD in dentistry and may soon replace MSCT, which is expensive and requires special facilities.

• Journal of Korean Neurosurgical Society
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• 제29권9호
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• pp.1233-1237
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• 2000

Objectives : In order to evaluate the metabolic changes associated with pericontusional edematous area in mild head injury, proton magnetic resonance spectroscopy(1H-MRS) was performed in mild head injury patients (initial GCS score 13-15) with focal brain contusion. Methods : Seven head injury patients with initial GCS 13-15(3 males and 4 females : age range 15-65 years, mean age 33 years) have underwent 1H-MRS evaluations. The patients were examined within 7 days after injury(n=7) and 2 months after injury(n=5). The region of interest(ROI) was selected in the edematous area adjacent to traumatic brain contusion upon T2-weighted MR images and a corresponding region of the contralateral hemisphere (ROC, region of contralateral corresponding hemisphere) was examined as well. The metabolic ratios of NAA/Cr and lactate/Cr were compared between ROIs, ROCs and control values. Results : In initial NAA/Cr ratios, the values of ROIs were significantly lower than those of the controls(p=0.009), but there was no difference either between ROIs and ROCs(p=0.410) or between ROCs of patients and the control (p=0.199). In lactate/Cr ratios, the ROIs in all seven patients and the ROCs in two showed increased lactate signals. The lactate/Cr ratios of the ROIs were significantly elevated as compared to those of the ROCs(p=0.02) and the control(p=0.015). In two months follow-up, lactate signals were absent or significantly reduced(p=0.015). In no patients, clinical or radiological deterioration has been observed. Conclusion : Our 1H-MRS results demonstrate that there are significant ischemic changes in pericontusional edematous areas as indicated by elevated lactate signals in the patients with mild head injury. But there were no consistent neural loss or dysfunction in these area. There findings suggest that pericontusional edematous areas can be vulnerable to secondary brain insults even in the patients with mild head injury.

• Journal of information and communication convergence engineering
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• 제6권4호
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• pp.425-429
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• 2008

We investigated algorithm to detect and characterize interstitial lung abnormalities seen at chest radiographs. This method includes a process of 4 directional Laplaction-Gaussian filtering, and a process of linear opacity judgment. Two regions of interest (ROIs) were selected in each right lung of patients, and these ROIs were processed by our computer-analyzing system. For quantitative analysis of interstitial opacities, the radiographic index, which is the percentage of opacity areas in a ROI, was obtained and evaluated in the images. From or result, abnormal lungs were well differentiated from normal lungs. In our algorithm, the processing results were not only given as the numeric data named "radiographic index" but also confirmed with radiologists observation on CRT. The approach, by which the interstitial abnormalities themselves are extracted, is good enough because the results can be confirmed by the observations of radiologists. In conclusion, our system is useful for the detection and characterization of interstitial lung abnormalities.