• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.24 no.6
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• pp.501-509
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• 2021

Extensive studies have shown that breast milk is the best source of nutrition for infants, especially during the first six months, because it fulfills almost all of their nutritional needs. Among the many functional building blocks in breast milk, human milk oligosaccharides (HMOs) have been receiving more attention recently. Furthermore, it is the third most common group of compounds in human milk, and studies have demonstrated the health benefits it provides for infants, including improved nutritional status. HMOs were previously known as the 'bifidus factor' due to their 'bifidogenic' or prebiotic effects, which enabled the nourishment of the gastrointestinal microbiota. Healthy gastrointestinal microbiota are intestinal health substrates that increase nutrient absorption and reduce the incidence of diarrhea. In addition, HMOs, directly and indirectly, protect infants against infections and strengthen their immune system, leading to a positive energy balance and promoting normal growth. Non-modifiable factors, such as genetics, and modifiable factors (e.g., maternal health, diet, nutritional status, environment) can influence the HMO profile. This review provides an overview of the current understanding of how HMOs can contribute to the prevention and treatment of nutritional issues during exclusive breastfeeding.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.3
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• pp.441-449
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• 2021

Bankruptcy is indicated by the inability of the company to meet its maturity obligations. The Covid-19 pandemic has had a terrible impact on the economy and businesses. The aim of this study to determine the effect of the ratios of activity, growth, leverage, and profitability in predicting bankruptcy projected by earnings per share (EPS). The sample of this research was non-banking financial sector companies listed on the Indonesia Stock Exchange in 2015-2019 and the purposive sampling technique was used. The data analysis method used was the logistic regression method to test the hypotheses. Company growth shows the company's ability to manage sales and generate high company profits, as such, the probability of the company experiencing bankruptcy will be lower. The results of this study showed that the debt to assets ratio (DAR), debt to equity ratio (DER), and return on assets (ROA) can predict bankruptcy. Meanwhile, this research found that the total assets turnover (TATO) ratio, sales growth, and net profit margin (NPM) cannot be used to predict bankruptcy.

• Journal of Genetic Medicine
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• v.18 no.2
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• pp.117-120
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• 2021

We experienced a case of Xq deletion -- 46,X,del(X)(q22.3) -- detected by abnormal noninvasive prenatal screening, subsequently diagnosed by amniocentesis. Genetic counseling was a challenge because there are few reports of prenatal diagnosis of Xq deletion. In each female cell, one X chromosome is inactivated at random early in development, and there may be a preferential inactivation of the abnormal X chromosome. But some proportions of genes escape inactivation. The most common manifestation in women with Xq deletion is primary or secondary ovarian failure. Critical regions for ovarian function may be located at the long arm of the X chromosome. But, the onset and the severity of ovarian failure may vary with diverse, intricate factors. We anticipate that noninvasive prenatal screening can identify the broader range of chromosomal or genetic abnormalities with the advances in technology and analytic methods. We report our case with a brief review of the literature.

• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.217-224
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• 2021

Rice blast caused by Pyricularia oryzae, which is a major threat to food security worldwide, markedly decreases the yield of rice. Some rhizobacteria called 'plant growth-promoting rhizobacteria' inhibit plant pathogens and improve plant growth by secreting iron-chelating siderophores. The decreased availability of iron adversely affects the survival of pathogens, especially fungal pathogens, in the rhizosphere. This study aimed to determine the morphological diversity of siderophore-producing bacteria, analyze the type of siderophores produced by the bacteria, and examine their growth-inhibitory activity against Pyricularia oryzae. The rhizobacteria were isolated from the rhizosphere of Sembada Hitam variety of black rice plants in Pakem, Sleman, Yogyakarta, Indonesia. In total, 12 distinct isolates were screened for the production of siderophores. It was found that 9 out of 12 bacteria produced siderophore and most of them were Gram positive bacteria. The best siderophore-producing isolates with different type of siderophore were used in further studies. The IS3 and IS14 isolates were found to be the best siderophore producer that produced hydroxamate and mixed type of hydroxamate-carboxylate type of siderophore, respectively. In the dual culture assay, IS14 showed a strong antagonistic effect against Pyricularia oryzae by the 81.17% inhibition.

• Journal of Elementary Mathematics Education in Korea
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• v.24 no.1
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• pp.151-168
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• 2020

The use of software is effective in developing mathematical understanding that provides mathematical problems and ensures mathematical communication. In particular, various software may provide all of the skills and conceptual activities students need to understand mathematical concepts. Based on these arguments, I analyze domestic prior studies based on the perspective of how the shape education using software affects mathematics learning. Based on the five categories of visualization, manipulation, cognitive tools, discourse promoters, and ways of thinking, domestic studies have shown that the number and categories of research related to shape education using software are limited. In addition, it was confirmed that previous studies in South Korea have been focused on the application of software rather than analysis of the changing aspects of learners' mathematics learning. These implications might be used as a basis for setting the direction of research on mathematics education related to the education of software utilization in the future.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.10
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• pp.4723-4727
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• 2016

Background: There are substantial differences in the mortality rates of stomach cancer among the 47 prefectures in Japan, and Aomori prefecture is one of the most severely impacted. The aims of this study were to determine the incidence and mortality rates of stomach cancer in Aomori prefecture in comparison with Japan as a whole and cast light on reasons underlying variation. Methods: Data on stomach cancer cases were extracted from the Aomori Cancer Registry Database. Incidence rates for specific stages at the time of diagnosis were cited from Monitoring of Cancer Incidence in Japan, and mortality rates for stomach cancer in Aomori prefecture and the whole of Japan were obtained from Vital Statistics. Age-standardised incidence and mortality rates were calculated using the direct method. Results: The age-standardised incidence rate of stomach cancer in Aomori prefecture was higher than in the whole of Japan for males but lower for females. However, the age-standardised mortality rates were higher in Aomori prefecture in both sexes. The proportion of localised cancers was lower in Aomori prefecture than in the whole of Japan for most age groups. Conclusions: The lower rate for localised cancer suggests that higher age-standardised mortality rates are due to delays in diagnosis, despite an attendance rate for stomach cancer screening was higher in Aomori prefecture than in the whole of Japan. One plausible explanation for the failure of successful early detection might be poor quality control during screening implementation that impedes early detection.

• Education of Primary School Mathematics
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• v.17 no.3
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• pp.173-188
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• 2014

The aim of the case study presented in this paper was to explore mathematics curriculum knowledge of a South Korean elementary teacher. An in-depth case study is applied to examine mathematics curriculum knowledge that influences teachers' instructional process including analysis of diverse artifacts such as lesson plan, observation and interviews. Findings of this study suggest that mathematics curriculum knowledge has direct relevance to teaching a lesson, designing a lesson and assessing students' work. In addition, this study identified that mathematics curriculum knowledge may be divided into two sub-categories: vertical mathematics curriculum knowledge and horizontal mathematics curriculum knowledge. The results of this case study help our understanding of South Korean elementary teachers' mathematics curriculum knowledge, which has a deep impact on their teaching practice. Moreover, this cross-national research offers implications for researchers, policymakers, and teachers in U.S. as well as those in South Korea.

• Communications of Mathematical Education
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• v.33 no.4
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• pp.445-453
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• 2019

Gender might be interpreted in different roles and meanings depending on social and cultural backgrounds. Based on the premise that understanding of gender may change the direction of mathematics education, this paper confirmed how gender is interpreted in the preceding study of mathematics education in Korea by applying the literature research method. In particular, predictive model based on empirical perspective and gender schema model based on constructivist perspective. Based on the analysis of gender and research methods in cultural and historical composition models based on historical perspectives and postmodernism models based on postmodernism perspectives, this study analyzed trends in domestic mathematics education. As a result of the analysis, it is confirmed that gender is recognized as a biological difference in domestic mathematics education, and that analysis of gender and related elements of mathematics education is mainly used using statistical analysis techniques. This suggests that various approaches to interpreting gender's role in future mathematics education are needed. The existing mathematics education research on gender is composed in terms of gender differences. Since biology at the time did not explain this difference, however, it should now be based on the concept of gender, which is socially defined gender. Accurate understanding of gender and gender can be the basis for clearer understanding and interpretation of gender-related mathematics research.

• Journal of Korean Society for Atmospheric Environment
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• v.29 no.3
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• pp.317-324
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• 2013

This research assessed the surface properties of modified activated carbons with three different acids and five different metals for ammonia gas removal. Raw bituminous coal-based activated carbon ($4{\times}8$ mesh) had low adsorption capacity of 0.72 mg $NH_3/g$ based on the analysis in the column adsorption experiment. Adsorption capacities of carbons modified with $CH_3COOH$, $H_3PO_4$, and $H_2SO_4$ increased up to 3.34, 21.00, and 35.21 mg $NH_3/g$, respectively. Those of carbons with Cu, Zn, Zr, Fe, and Sn were 9.63, 9.13, 7.09, 25.12 and 15.03 mg $NH_3/g$. Ammonia adsorption was enhanced by the presence of surface oxygen groups on carbon materials, which influenced pH of carbon surface. BET surface area of raw carbon was analyzed to be $1087m^2/g$, but it decreased by carbon surface modification. Fe-impregnated carbon showed $503.02m^2/g$ of surface area. These observations were mostly caused by chemical adsorption.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.11
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• pp.5025-5030
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• 2016

The objective of this study was to clarify how distance from place of residence to the nearest specialist cancer hospital affects the survival of lung cancer patients and the treatment received. For all patients diagnosed with lung cancer in the Aomori cancer registry database for the period from 2009 to 2011 (n=3,986). The distance to the treating hospital was measured as the straight line from a person's place of residence, and compared with findings from the Ederer II method for calculating relative survival. Information on treatments given was obtained by data extraction. We defined a hospital having respiratory medicine as specialist, while all private hospitals and clinics were included in the general category. Patients attending specialist hospitals numbered 2,548 (67.0%), and those treated at general institutions were 1,255 (33.0%). The patients who had the lowest relative survival with localized lesions lived <20 km from general hospitals and clinics. With more advanced stages, relative survival of those living <20 km from a specialist hospital was the lowest. Although the survival rate was not affected by the distance between place of residence and hospital, even when patients are diagnosed at a localized stage at a general hospital or clinic within 20 km from their home, they did survive longer in comparison with patients diagnosed at a specialist hospital.