• Childhood Kidney Diseases
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• v.3 no.2
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• pp.187-195
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• 1999

Purpose : VUR is state where urine regurge from bladder to ureter and kidney. It is shown in about 1/3 of urinary tract infection patients and it is classified as grade I to V. We compared results from RI VCUG(Radiisotope voiding cystourethrography) and X-ray VCUG which used in diagnosing VUR in children, to evaluate which is better in diagnosing VUR in children. Methods : 41 Patients(19 males, 21 females), who visited Pediatric department, Soonchunhyang university Hospital from peroid of 1991. January to 1998. July for recurrent urinary tract infection or abnormalities in ultrasonogams, were enrolled in the study. The age ranged from 9 months to 17 years and mean age was 5 1/2 years. Both RI VCUG and X-ray VCUG were done and follow-up test of urine culture, renal ultrasonogram and RI VCUG were done every month, every 3 month and every 6 month, respectively to observe the disappearance of VUR and evaluated the prognosis. Results : 24 patients had taken RI VCUG and 17(70.1%) patients showed positive result. 22 patients had taken X-ray VCUG and 9(40.1%) patients showed findings of VUR. 17 patients had taken both tests and 14 patients showed positive result in RI VCUG and 6 of these patients also showed reflux in X-ray VCUG. 3 patients who showed negative in RI VCUG, showed negative also in X-ray VCUG. For prognosis, resolution and scar formation was shown in 8 patients each. Persistent VUR was shown in 6 patients and 2 of these patients VUR was corrected by operation, 1 patient showed decreased renal function, and 1 patient was not follwed up. 8 of 9 patients who showed findings of VUR on DMSA scan formed a scar and 8 patients who showed no findings of VUR didn't form a scar. Urine culture was positive in 17 of 19 patients with VUR. Positive rate in urine culture was higher than that of patients with no VUR who showed positivity in 15 of 21 patients for urine culture. E. coli was most common organism and the period free of UTI was 14 months in VUR patients and it was shorter compared to patients without VUR which was 26 months. Conclusion : In diagnosing VUR in children, the positive rate was higher in RI VCUG than X-ray VCUG. Therefore, in early diagnosis when VUR is suspicious but not shown in X-ray VCUG, RI VCUG should be done and it will help to make accurate diagnosis.

• Korean Journal of Environment and Ecology
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• v.28 no.5
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• pp.559-565
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• 2014

The fish and attached fish eggs by artificial floating island in lake Soyang was investigation from May to June 2013. The observed fish at the floating island during the survey period were Zacco platypus (5.2 %), Siniperca scherzeri (1.0 %), Lepomis macrochirus (90.8 %) and Micropterus salmoides (3.0 %) at the Cheongpyeong-ri, Cyprinus carpio (0.4 %), Z. platypus (54.6 %), L. macrochirus (20.3 %) and M. salmoides (24.7 %) at the Ungjin-ri. The collected species at the neighboring facility were 22 species belonging the seven families. Among them, exotic species such as Carassius cuvieri, L. macrochirus and M. salmoides. Also, Z. platypus (30.4 %), L. macrochirus (18.9 %), Opsariichthys uncirostris amurensis (15.4 %) and Hemibarbus labeo (9.3 %) were numberous. Attached fish eggs number were 708,800 (800 per $m^2$) at the Cheongpyeong-ri and 974,500 (1,100 per $m^2$) at the Ungjin-ri. The fish eggs number were 504,920 of the Carassius auratus (212,640 at the Cheongpyeong-ri, 292,280 at the Ungjin-ri) and 1,178,380 of the C. carpio (496,160 at the Cheongpyeong-ri, 682,220 at the Ungjin-ri). The hatched eggs number were 350,505 of the C. auratus(102,067 at the Cheongpyeong-ri, 248,438 at the Ungjin-ri) and 811,222 of the C. carpio (238,157 at the Cheongpyeong-ri, 573,065 at the Ungjin-ri).

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.6
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• pp.63-77
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• 2006

The research aim is to classify biotope types of rural eco-villages designed by ministry of environment and analyze landscape ecological characteristics of them. This information would provide information on eco-villages' potential and specific needs to improve landscape ecological structure of eco-villages. Two eco-villages, designated by ministry of environment, in Yoocheon-ri and Sanduk-ri were selected and the landscape ecological metrics used in this study were Area, Shannon diversity index, Shape index, Distance index. The results are as follows. 1) There were five biotope types in large-scale classification, 13 biotope types m Sanduk-ri and 9 biotope types in Yoocheon-ri in middle-scale classification, 31 biotope types in Sanduk-ri and 24 biotope types in Yoocheon-ri in small-scale classification. 2) In the case of area, artificial biotope types, such as artificial forest, agricultural irrigation canal, wet paddy, dry paddy and residential area, covered more than 80% of total area. However, natural biotope types, such as natural forest, river, reservoir, covered just more than 10% of total area. In details, an orchard (26.69%) was the dominant biotope type, followed by artificial forest (19.10%) in Sanduk-ri and the first most abundant biotope type was artificial forest (49.71%), followed by wet paddy (15.95%) in Yoocheon-ri. 3) The result of Shannon diversity index indicated that Sanduk-ri (2.158) had more heterogeneity landscape, rather than Yoocheon-ri (2.051). 4) In the case of shape index, road (13.09) had more complex and irregular shape than either agricultural irrigation canal (3.35) or artificial forest (2.46) in Sanduk-ri. Road (6.52) was also the most irregular biotope shape, followed by river (5.70) and agricultural irrigation canal (4.78) in Yoocheon-ri. 5) Mean Nearest-neighbour Distance (MND) was smallest in wet paddy and dry paddy biotope types in the two study area, suggesting that these biotope types were concentrated within these study areas. From the result, this research suggested information to protect and improve biotopes of eco-villages in the landscape ecological terms. To achieve this improvement plan, there should be strong support by ministry of environment and local governments.

• Korean Journal of Microbiology
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• v.52 no.1
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• pp.120-124
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• 2016

A certain size of DNA (28-29 kb long) to be packaged into P2-size head and the mutation in sid gene of bacteriophage P4 are the major factors to overcome "P2 sir-associated helper inefficiency". To clarify whether the presence of sid mutation is essential to overcome "P2 sir-associated helper inefficiency" or not, we tested the P4 derivative, P4 delRI::kmr, which is $sid^+$ and whose genome size supposed to be 28.5 kb long in the case of being packaged into $P2_{sir3}$-sized large head. As P4 delRI::kmr showed the low EOP with P2 sir3 lysogen, P4 delRI::kmr phage stock was prepared in P2 sir3 lysogen host to increase the EOP with P2 sir3 lysogen. Through this process, P4 delRI::kmr had been adapted for P2 sir3 lysogen. With a CsCl buoyant equilibrium density gradient experiment and gel electrophoresis of the isolated DNA, it was evident that the adaptation of P4 delRI::kmr for P2 sir3 lysogen was caused by the conformational change of DNA to be packaged into large head. The burst size determination experiments with P4 delRI::kmr phage stock adapted for P2 sir3 lysogen and normal P4 delRI::kmr phage stock showed that not the sid mutation but the size of DNA to be packaged (28-29 kb long) was essential to overcome "P2 sir-associated helper inefficiency".

• Korean Journal of Food Science and Technology
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• v.34 no.3
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• pp.351-355
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• 2002

Volatile compounds of kimchi-flavored steak sauce were isolated using simultaneous steam distillation and solvent extraction methods and identified by matching mass spectrum and retention index (RI) with the reference data. Twenty-three compounds including five aldehydes, four alcohols, four acids, three sulfur-containing compounds, one ketone, and six others were identified, among which the most abundant compound was eugenol. Sulfides such as dimethyl dis- and trisulfides, and acids such as acetic and dodecanoic acids showed strong effects on the kimchi flavor. Aroma extract dilution analysis with three fold dilution factor shown in over the FD value 34 identified 2-butanal, 2-pentylfuran, methyl-2-propenyl disulfide, and 2-furanmethanol. Strong good aroma was detected in the RI range between 1030 and 1357, bad aroma in RI 1561, sweety aroma in RI 2057, clover aroma of eugenol in RI 2122, and rancid flavor in RI 2251.

• Animal Bioscience
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• v.35 no.7
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• pp.964-974
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• 2022

Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry and economy and remains a potential source of pandemic infection in humans. Antiviral genes are considered a potential factor for studies on HPAIV resistance. Therefore, in this study, we investigated gene expression related to the mitogen-activated protein kinase (MAPK) signaling pathway by comparing non-infected, HPAI-infected resistant, and susceptible Ri chicken lines. Methods: Resistant (Mx/A; BF2/B21) and susceptible Ri chickens (Mx/G; BF2/B13) were selected by genotyping the Mx and BF2 genes. Then, the tracheal tissues of non-infected and HPAIV H5N1 infected chickens were collected for RNA sequencing. Results: A gene set overlapping test between the analyzed differentially expressed genes (DEGs) and functionally categorized genes was performed, including biological processes of the gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathways. A total of 1,794 DEGs were observed between control and H5N1-infected resistant Ri chickens, 432 DEGs between control and infected susceptible Ri chickens, and 1,202 DEGs between infected susceptible and infected resistant Ri chickens. The expression levels of MAPK signaling pathway-related genes (including MyD88, NF-κB, AP-1, c-fos, Jun, JunD, MAX, c-Myc), cytokines (IL-1β, IL-6, IL-8), type I interferons (IFN-α, IFN-β), and IFN-stimulated genes (Mx1, CCL19, OASL, and PRK) were higher in H5N1-infected than in non-infected resistant Ri chickens. MyD88, Jun, JunD, MAX, cytokines, chemokines, IFNs, and IFN-stimulated expressed genes were higher in resistant-infected than in susceptible-infected Ri chickens. Conclusion: Resistant Ri chickens showed higher antiviral activity compared to susceptible Ri chickens, and H5N1-infected resistant Ri chickens had immune responses and antiviral activity (cytokines, chemokines, interferons, and IFN-stimulated genes), which may have been induced through the MAPK signaling pathway in response to H5N1 infection.

• Nuclear industry
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• v.5 no.7 s.29
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• pp.18-21
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• 1985

1930년이래 원자로나 입자가속기를 이용하여 여러 종류의 방사성동위원소(Radioisotope, RI)를 인공적으로 생산하게 됨에 따라 1960년대부터는 인공 RI를 여러 분야에서 이용하게 되었고, 우리나라에서도 상당량의 RI 및 그 표식화합물들을 생산 또는 수입하여 이용함으로써 우리 생활과 밀접한 관계를 갖게 되었다. 더구나 천연자원이 부족한 우리나라는 원자력발전을 통하여 그 돌파구를 찾지 않을 수 없게 됨에 따라 원자력은 우리 앞에 성큼 다가왔고 여러가지 RI 및 방사선에 대한 관심도 높아졌다. 즉, 우리는 이제 원자력시대에 살고 있어 이와 관련한 기본지식을 외면하는 것은 곧 현실을 외면하는 것이 되었다. 최첨단 거대과학, 그 한쪽 분야를 살펴 보기로 하자.

• Journal of Pharmacopuncture
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• v.15 no.4
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• pp.32-41
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• 2012

Objectives: Rehmannia glutinosa pharmacopuncture solution (RGPS) was investigated to determine both its anti-allergic inflammatory effects on mast cells and its detailed mechanism of actions. Methods: We investigated whether RGPS suppress cytokines, enzymes, $Fc{\varepsilon}RI$ expression and $Fc{\varepsilon}RI$-mediated signaling in RBL-2H3 cells stimulated with anti-DNP IgE/DNP-HSA. The suppressive effects of RGPS on the levels of cytokines such as IL-$1{\beta}$, IL-6 and GM-CSF were measured using emzyme-linked immunospecific assay (ELISA). The mRNA expression levels of cytokines, enzymes (HDC2, COX-1, COX-2 and 5LO) and $Fc{\varepsilon}RI$ ${\alpha}{\beta}{\gamma}$ subunits were measured using reverse transcription polymerase chain reaction (RT-PCR) method. The activation of $Fc{\varepsilon}RI$-mediated signaling was examined using Western blot analyses. Results: RGPS suppressed production of proinflammatory cytokines (IL-$1{\beta}$, IL-6, and GM-CSF) in stimulated RBL-2H3 cells significantly (p < 0.05). RGPS also suppressed mRNA expression of inflammatory enzymes (HDC2, COX-1, COX-2, 5LO). In addition, mRNA expression levels of $Fc{\varepsilon}RI{\alpha}$, $Fc{\varepsilon}RI{\beta}$and $Fc{\varepsilon}RI{\gamma}$ were lowered by treatment with RGPS. Finally, RGPS prevented phosphrylation of Lyn, Syk, LAT, Gab2, PLC ${\gamma}1/2$, PI3K, Akt, cPLA2 and $I{\kappa}B{\alpha}$. Conclusions: RGPS effectively suppresses mast cell activations such as degranulation and inflammatory response via down-regulation of the $Fc{\varepsilon}RI$-mediated signaling pathways in IgE/Ag-stimulated mast cells.

• Journal of the Korean association of regional geographers
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• v.14 no.4
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• pp.279-289
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• 2008

The purpose of this paper is to search for geomorphological landscape resources of Goryeong-gun, to provide fundamental data for their management through mapping their distribution, and to present their conservation and application plan. The results are as follow: Firstly, geomorphological landscape resources in mountain area are Misungsan and Jusan mountain of Goryeong-up, Sangbiri valley of Deoggok-myeon, and isolated hill of Gaejin-myeon. Secondly, geomorphological landscape resources in riparian area are natural wetlands such as Jinchonneup of Bu-ri Gaejin-myeon, Hochonneup and Dalseongseupji of Hochon-ri Dasan-myeon, Bongsanneup of Bongsan-ri Ugok- myeon; artificial wetlands following the construction of weir such as riparian wetland of Oe-ri Goryeong-up and Banun-ri Gaejin-myeon; meander core and abandoned channel of Banun-ri Gaejin -myeon, river cliffs such as Naegok-ri Goryeong-up and Weolo-ri Ugok-myeon; sand bars and braided channel of Yajeong-ri Ugok-myeon. Thirdly, Jinchonneup swamp area of Bu-ri Gaejin-myeon have characteristics of typical floodplain landform, and its conservation conditions is relatively satisfactory, and its accessibility to metropolis is great, so it is a good place to construct eco-park. And construction of inquiry learning place at Banun-ri Gaejin-myeon will increase the opportunity to observe environmental changes following incised meander cutoff and ecological affirmative functions of a weir.

• Korean Journal of Heritage: History & Science
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• v.54 no.2
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• pp.98-119
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• 2021

This thesis aims to examine when the petroglyphs of Cheonjeon-ri, Ulju were carved and their nature. To achieve this, the relations between rituals and rock carving motifs are examined besides the nature of the archaeological monuments with carved petroglyphs. The investigation revealed that the figurative motifs on the petroglyphs of Cheonjeon-ri, Ulju, may have been carved during the Korean Bronze Age considering other examples of figurative petroglyphs from that period. It is reasonable to assume that the figurative animal motifs on the petroglyphs of Cheonjeon-ri, Ulju were used for rituals of fertility and rebirth as a subsistence ritual during the Korean Bronze Age. The Geomdan-ri Archaeological Culture Type is a strong candidate, having used both petroglyphs of Cheonjeon-ri and those of Bangudae, Ulju, since the Geomdan-ri Archaeological Culture Type has a higher proportion of hunting and fishing and lower proportion of rice cultivation in its subsistence than in the subsistence of the Songguk-ri Archaeological Culture Type. In contrast to the figurative motifs, the abstractive motifs, including the geometric designs on the petroglyphs of Cheonjeon-ri, Ulju, are generally accepted to have been carved during the Bronze Age. Although there have been some disputes over the symbolic meanings of concentric motifs, lozenge motifs, and other geometric motifs, they may be related to rituals for sun worship, ancestor worship, and fertility cults. Their meanings have been continuously reinterpreted.