• 한국정보통신학회논문지
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• 제21권11호
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• pp.2037-2042
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• 2017

스마트 공장은 미리 입력된 프로그램에 의해 생산시설이 수동적으로 움직이는 공장 자동화 작업 방식과는 달리, 생산 설비 스스로 작업 방식을 결정하여야 한다. 생산 설비 스스로 작업 방식을 결정이라 함은, 이를테면 제조 현장에서 설비의 노후, 문제 발생 예측, 제품의 불량 검출 등과 같은 이상 징후가 발생할 시 이를 조기에 발견한 후 스스로 문제를 해결하는 것을 의미한다. 본 논문에서는 제조 현장의 제조 공정 이상 징후 감지를 위해 대기행렬을 이용한 제조 공정 모델링을 제시하고 해당 모델링에서 이상 징후를 기계학습 기술 중 하나인 SVM을 이용하여 이를 감지하도록 한다. 해당 대기행렬을 M/D/1을 사용하였으며, ${\mu}$, ${\lambda}$, ${\rho}$를 기반으로 컨베이어 벨트 제조 시스템을 모델링하였다. SVM을 이용하여 ${\rho}$의 변화량을 통해 이상 징후를 감지했다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 하계학술대회 논문집 Vol.3 No.2
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• pp.764-768
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• 2002

Characteristics of ohmic Co/Si/Co contacts to n-type 4H-SiC are investigated systematically. The ohmic contacts were formed by annealing Co/Si/Co sputtered sequentially. The annealings were performed at $800^{\circ}C$ using RTP in vacuum ambient and $Ar:H_2$(9:1) ambient, respectively. The specific contact resistivity$(\rho_c)$, sheet resistance$(R_s)$, contact resistance$(R_c)$, transfer length$(L_T)$ were calculated from resistance$(R_T)$ versus contact spacing(d) measurements obtained from TLM(transmission line method) structure. While the resulting measurement values of sample annealed at vacuum ambient were $\rho_c=1.0{\tiimes}10^{-5}{\Omega}cm^2$, $R_c=20{\Omega}$ and $L_T$ = 6.0 those of sample annealed at $Ar:H_2$(9:1) ambient were $\rho_c=4.0{\tiimes}10^{-6}{\Omega}cm^2$, $R_c=4.0{\Omega}$ and $L_T$ = 2.0. The physical properties of contacts were examined using XRD and AES. The results showed that cobalt silicide was formed on SiC and Co was migrated into SiC.

• 대한화학회지
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• 제41권3호
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• pp.138-143
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• 1997

30$^{\circ}C$의 센(-Ho < 2.23) 과염소산 수용액 속에서 3,3-bis(methylthio)-2-propen-1-phenyl-1-one 유도체들의 산-촉매 가수분해 반응을 속도론적으로 연구하였다. 치환기 효과, 가수분해 생성물의 분석, Bunnett식 및 Bunnett-Olsen식의 hydration 파라미터(${\omega}$및 ${\phi}$)로부터 3.8 M 이하의 묽은 산 용액에서는 A-1형 반응($3.3 >{\omega},\;0.58 > {\phi}$ 및 ${\rho} < 0$)이 그리고 3.8 M 이상의 진한 산 용액에서는 A-2형 반응($0 <{\omega},\;0 < {\phi}$ 및 ${\rho} > 0$) 메카니즘으로 산-촉매 가수분해 반응이 일어난다.

• Journal of Korean Biological Nursing Science
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• 제18권4호
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• pp.203-212
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• 2016

Purpose: The purpose of this study was to identify the sleep patterns of nursing students using self-report questionnaire and physiologic measurement, to examine the factors influencing sleep patterns in based on Spielman's model. Methods: Participants were 119 nursing students who were in the clinical practice period. Self-report questionnaires and actigraphy were used to collect the data. Data were analyzed using descriptive statistics, correlation and regression by the SPSS/WIN 21.0 programs. Results: When sleep was measured by self-report questionnaire, 84 students (70.6%) showed poor sleep quality. The mean sleep efficiency was 82.6%, and 67 students(56.3%) showed low sleep efficiency (less than 85.0%). The factors affecting subjective sleep pattern measured by KMLSEQ were circadian sleep type (${\beta}=.28$, ${\rho}=.003$) and alcohol (${\beta}=.20$, ${\rho}=.031$). The factors affecting total sleep time were sedentary behavior (${\beta}=-.27$, ${\rho}=.003$) and daytime sleepiness (${\beta}=-.33$, ${\rho}$<.001). Conclusion: Many nursing students in their clinical practice period expressed sleep disturbance. Factors affecting the perceived sleep measured by the self-report questionnaire and objective sleep evaluated by physiologic measures were different. The evening type of students perceived poor sleep quality, however, sedentary life style and daytime sleepiness resulted in short sleep time. Therefore, more studies measuring the objective sleep characteristics are needed using subjective and objective characteristics.

• BMB Reports
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• 제51권6호
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• pp.296-301
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• 2018

Mitochondrial DNA (mtDNA) mutations are often observed in various cancer types. Although the correlation between mitochondrial dysfunction and cancer malignancy has been demonstrated by several studies, further research is required to elucidate the molecular mechanisms underlying accelerated tumor development and progression due to mitochondrial mutations. We generated an mtDNA-depleted cell line, ${\rho}^0$, via long-term ethidium bromide treatment to define the molecular mechanisms of tumor malignancy induced by mitochondrial dysfunction. Mitochondrial dysfunction in ${\rho}^0$ cells reduced drug-induced cell death and decreased the expression of pro-apoptotic proteins including p53. The p53 expression was reduced by activation of nuclear $factor-{\kappa}B$ that depended on elevated levels of free calcium in $HCT116/{\rho}^0$ cells. Overall, these data provide a novel mechanism for tumor development and drug resistance due to mitochondrial dysfunction.

• Advances in Computational Design
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• 제3권1호
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• pp.49-69
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• 2018

This paper shows an optimal design for reinforced concrete rectangular combined footings based on a criterion of minimum cost. The classical design method for reinforced concrete rectangular combined footings is: First, a dimension is proposed that should comply with the allowable stresses (Minimum stress should be equal or greater than zero, and maximum stress must be equal or less than the allowable capacity withstand by the soil); subsequently, the effective depth is obtained due to the maximum moment and this effective depth is checked against the bending shear and the punching shear until, it complies with these conditions, and then the steel reinforcement is obtained, but this is not guaranteed that obtained cost is a minimum cost. A numerical experimentation shows the model capability to estimate the minimum cost design of the materials used for a rectangular combined footing that supports two columns under an axial load and moments in two directions at each column in accordance to the building code requirements for structural concrete and commentary (ACI 318S-14). Numerical experimentation is developed by modifying the values of the rectangular combined footing to from "d" (Effective depth), "b" (Short dimension), "a" (Greater dimension), "${\rho}_{P1}$" (Ratio of reinforcement steel under column 1), "${\rho}_{P2}$" (Ratio of reinforcement steel under column 2), "${\rho}_{yLB}$" (Ratio of longitudinal reinforcement steel in the bottom), "${\rho}_{yLT}$" (Ratio of longitudinal reinforcement steel at the top). Results show that the optimal design is more economical and more precise with respect to the classical design. Therefore, the optimal design presented in this paper should be used to obtain the minimum cost design for reinforced concrete rectangular combined footings.

• 대한화학회지
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• 제38권5호
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• pp.391-396
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• 1994

강산성 용액에서 $\alpha$-벤족시스티렌(1)의 가수분해를 속도론적으로 다루었다. 과염소산이 5.5M보다 낮은 농도($H_o$ < -3.0)에서 수화파라메타 $\omega$ = + 7.6, $\Phi$ = + 0.54를 얻었다. 용매동위원소효과 $k_{H_2O}/k_{D_2O}$는 0.72였고, Hammett $\sigma^+$ 상수에 대한 치환기 효과 $\rho$ = -0.60이었다. 이 결과와 다른 증거로부터 이 산도 범위에서 엔올에스테르의 가수분해는 $A_{AL}$2 형태의 메카니즘에 의해 진행되었다. 과염소산 농도가 5.5 M 이상에서는 동위원소효과, $k_{H_2O}/_{D_2O}$는 3.32이었고, 치환기 효과, $\rho$=-1.6이었으며, 속도상수는 산도함수, $H_o$에 비례하였다. 따라서 반응메카니즘은 변하여 올레핀이 양성자화되는 첫단계가 속도결정단계가 된다.

• 한국철도학회논문집
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• 제9권4호
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• pp.371-378
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• 2006

This study investigates the effects of the material properties and the fatigue behaviors in the SM490A material butt weld specimens due to the heat-treatment and the grinding. In the fatigue behavior, the heat-treatment affects the fatigue life. The S-N curves of both matrix specimen and butt weld specimen are reversed at some cycle by the existence or nonexistence of heat-treatment. The grinding on the bead makes the fatigue limit decrease in the all specimens. But the reinforcement removed, the fatigue limit increases at the high cycle. Also, this study investigates the fatigue life estimation by examining butt weld bead profiles. The butt weld beads, which are welded by semi-robot method, have non-uniform bead profiles described by $\theta,\;\rho$ and h. The stress concentration factors $K_t$, are changed by each different $\theta,\;\rho$ and h from 1.395 to 2.863. Hence, the sensitivity of $K_t$ is changed by each $\theta,\;\rho$ and h. As $\theta$ becomes lower and $\rho$ and h become higher, $K_t$ increases. The fatigue life can he estimated very closely for the AAY specimens without residual stress using only butt weld bead profiles. But, fur the AAN specimens with residual stress, the fatigue life must be estimated by considering both the weld bead profiles and the residual stress data.

• 수산해양기술연구
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• 제20권2호
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• pp.137-142
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• 1984

수평관내 증기분무류의 응축열전달에 관하여 실험을 행하고 상당 Reynolds수를 근거로한 열전달효과와의 비교에서 그 결과를 요약하면 다음과 같다. 1. 관내 응축증기 분무류일 경우의 벽면전단응력의 식은 다음과 같이 쓸 수 있다. root($\tau$하(0)/$\tau$하(0v))=1+1.46X 하(tt) 상(0.20). 2. 분무류의 응축열전달효과가 상당 Reynolds수에 의한 값보다 대체로 낮게 나타난 이유는 관내 반경 및 길이방향의 불균일한 액막형성에 의한 Reynolds수 측정값의 차이 때문이다. 3. 분무류의 응축열전달효과에 의한 N sub(u)의 값은 다음과 같다. N 하(u)=1.08$\times$[{$\rho$ 하(l) d/$\mu$ 하(l)}/{$\delta$+(2.5/P 하(rl)) ln(y 하(i)/$\delta$)}]$\times${$\tau$ 하(0)/ $\rho$ 하(l)} 상(1/2)

• BMB Reports
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• 제50권6호
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• pp.335-340
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• 2017

Although doxorubicin (Dox)-induced oxidative stress is known to be associated with cytotoxicity, the precise mechanism remains unclear. Genotoxic stress not only generates free radicals, but also affects actin cytoskeleton stability. We showed that Dox-induced RhoA signaling stimulated actin cytoskeleton alterations, resulting in central stress fiber disruption at early time points and cell periphery cortical actin formation at a later stage, in HeLa cells. Interestingly, activation of a cofilin phosphatase, chronophin (CIN), was initially evoked by Dox-induced RhoA signaling, resulting in a rapid phosphorylated cofilin turnover leading to actin cytoskeleton remodeling. In addition, a novel interaction between CIN and $14-3-3{\zeta}$ was detected in the absence of Dox treatment. We demonstrated that CIN activity is quite contrary to $14-3-3{\zeta}$ binding, and the interaction leads to enhanced phosphorylated cofilin levels. Therefore, initial CIN activation regulation could be critical in Dox-induced actin cytoskeleton remodeling through RhoA/cofilin signaling.