• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.11
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• pp.2037-2042
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• 2017

The manufacturing facility is generally operated by a pre-set program under the existing factory automation system. On the other hand, the manufacturing facility must decide how to operate autonomously in Industry 4.0. Determining the operation mode of the production facility itself means, for example, that it detects the abnormality such as the deterioration of the facility at the shop-floor, prediction of the occurrence of the problem, detection of the defect of the product, In this paper, we propose a manufacturing process modeling using a queue for detection of manufacturing process abnormalities at the shop-floor, and detect abnormalities in the modeling using SVM, one of the machine learning techniques. The queue was used for M / D / 1 and the conveyor belt manufacturing system was modeled based on ${\mu}$, ${\lambda}$, and ${\rho}$. SVM was used to detect anomalous signs through changes in ${\rho}$.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.764-768
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• 2002

Characteristics of ohmic Co/Si/Co contacts to n-type 4H-SiC are investigated systematically. The ohmic contacts were formed by annealing Co/Si/Co sputtered sequentially. The annealings were performed at $800^{\circ}C$ using RTP in vacuum ambient and $Ar:H_2$(9:1) ambient, respectively. The specific contact resistivity$(\rho_c)$, sheet resistance$(R_s)$, contact resistance$(R_c)$, transfer length$(L_T)$ were calculated from resistance$(R_T)$ versus contact spacing(d) measurements obtained from TLM(transmission line method) structure. While the resulting measurement values of sample annealed at vacuum ambient were $\rho_c=1.0{\tiimes}10^{-5}{\Omega}cm^2$, $R_c=20{\Omega}$ and $L_T$ = 6.0 those of sample annealed at $Ar:H_2$(9:1) ambient were $\rho_c=4.0{\tiimes}10^{-6}{\Omega}cm^2$, $R_c=4.0{\Omega}$ and $L_T$ = 2.0. The physical properties of contacts were examined using XRD and AES. The results showed that cobalt silicide was formed on SiC and Co was migrated into SiC.

• Journal of the Korean Chemical Society
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• v.41 no.3
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• pp.138-143
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• 1997

Acid-catalyzed hydrolysis of 3,3-bis(methylthio)-2-propen-1-phenyl-1-one derivatives were studied kinetically in concentrated aqueous hydroperchloric acid(-Ho < 2.23) at $30^{\circ}C.$ The substituent effect, analysis of hydrolysis product, hydration $parameter({\omega} & {\phi}$) from the Bunnett equation and the Bunnett-Olsen equation on the rate indicate that the acid-catalyzed hydrolysis of the substrates below 3.8 M hydroperchloric acid media occurs through A-1 type reaction($3.3 >{\omega},\;0.58 >{\phi} & {\rho}< 0$) mechanism and above 3.8 M hydroperchloric acid, the reaction proceeds A-2 type reaction($0 <(\omega)$, $0 <{\phi} & (\rho)> 0$) mechanism.

• Journal of Korean Biological Nursing Science
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• v.18 no.4
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• pp.203-212
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• 2016

Purpose: The purpose of this study was to identify the sleep patterns of nursing students using self-report questionnaire and physiologic measurement, to examine the factors influencing sleep patterns in based on Spielman's model. Methods: Participants were 119 nursing students who were in the clinical practice period. Self-report questionnaires and actigraphy were used to collect the data. Data were analyzed using descriptive statistics, correlation and regression by the SPSS/WIN 21.0 programs. Results: When sleep was measured by self-report questionnaire, 84 students (70.6%) showed poor sleep quality. The mean sleep efficiency was 82.6%, and 67 students(56.3%) showed low sleep efficiency (less than 85.0%). The factors affecting subjective sleep pattern measured by KMLSEQ were circadian sleep type (${\beta}=.28$, ${\rho}=.003$) and alcohol (${\beta}=.20$, ${\rho}=.031$). The factors affecting total sleep time were sedentary behavior (${\beta}=-.27$, ${\rho}=.003$) and daytime sleepiness (${\beta}=-.33$, ${\rho}$<.001). Conclusion: Many nursing students in their clinical practice period expressed sleep disturbance. Factors affecting the perceived sleep measured by the self-report questionnaire and objective sleep evaluated by physiologic measures were different. The evening type of students perceived poor sleep quality, however, sedentary life style and daytime sleepiness resulted in short sleep time. Therefore, more studies measuring the objective sleep characteristics are needed using subjective and objective characteristics.

• BMB Reports
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• v.51 no.6
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• pp.296-301
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• 2018

Mitochondrial DNA (mtDNA) mutations are often observed in various cancer types. Although the correlation between mitochondrial dysfunction and cancer malignancy has been demonstrated by several studies, further research is required to elucidate the molecular mechanisms underlying accelerated tumor development and progression due to mitochondrial mutations. We generated an mtDNA-depleted cell line, ${\rho}^0$, via long-term ethidium bromide treatment to define the molecular mechanisms of tumor malignancy induced by mitochondrial dysfunction. Mitochondrial dysfunction in ${\rho}^0$ cells reduced drug-induced cell death and decreased the expression of pro-apoptotic proteins including p53. The p53 expression was reduced by activation of nuclear $factor-{\kappa}B$ that depended on elevated levels of free calcium in $HCT116/{\rho}^0$ cells. Overall, these data provide a novel mechanism for tumor development and drug resistance due to mitochondrial dysfunction.

• Advances in Computational Design
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• v.3 no.1
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• pp.49-69
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• 2018

This paper shows an optimal design for reinforced concrete rectangular combined footings based on a criterion of minimum cost. The classical design method for reinforced concrete rectangular combined footings is: First, a dimension is proposed that should comply with the allowable stresses (Minimum stress should be equal or greater than zero, and maximum stress must be equal or less than the allowable capacity withstand by the soil); subsequently, the effective depth is obtained due to the maximum moment and this effective depth is checked against the bending shear and the punching shear until, it complies with these conditions, and then the steel reinforcement is obtained, but this is not guaranteed that obtained cost is a minimum cost. A numerical experimentation shows the model capability to estimate the minimum cost design of the materials used for a rectangular combined footing that supports two columns under an axial load and moments in two directions at each column in accordance to the building code requirements for structural concrete and commentary (ACI 318S-14). Numerical experimentation is developed by modifying the values of the rectangular combined footing to from "d" (Effective depth), "b" (Short dimension), "a" (Greater dimension), "${\rho}_{P1}$" (Ratio of reinforcement steel under column 1), "${\rho}_{P2}$" (Ratio of reinforcement steel under column 2), "${\rho}_{yLB}$" (Ratio of longitudinal reinforcement steel in the bottom), "${\rho}_{yLT}$" (Ratio of longitudinal reinforcement steel at the top). Results show that the optimal design is more economical and more precise with respect to the classical design. Therefore, the optimal design presented in this paper should be used to obtain the minimum cost design for reinforced concrete rectangular combined footings.

• Journal of the Korean Chemical Society
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• v.38 no.5
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• pp.391-396
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• 1994

The hydrolysis of $\alpha-benzoxystyrene(1)$ in strong acidic solution has been investigated kinetically. In perchloric acid concentration lower than 5.5 M($H_o$ < -3.0), hydration paramer $\omega$ = + 7.6, and $\Phi$ = + 0.54 were obtained. The solvent isotope effect $k_{H_2O}/K_{D_2O}$ is 0.72. The substituent effect was found to conform to the Hammett $\sigma^+$ constant with $\rho$ = -0.60. On the basis of these results and other evidence, the hydrolysis of the enol ester proceeds by $A_{AL}$2 type mechanism. In concentration greater than 5.5 M($H_o$ > -3.0), isotope effect, $k_{H_2O}/_{D_2O}$ is 3.32, substituent effect, $\rho$ is -1.60 and the rate is linear with the acidity function, $H_o$. Thus, the mechanism changes one involving initial, and rate-determining olefin protonation.

• Journal of the Korean Society for Railway
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• v.9 no.4 s.35
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• pp.371-378
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• 2006

This study investigates the effects of the material properties and the fatigue behaviors in the SM490A material butt weld specimens due to the heat-treatment and the grinding. In the fatigue behavior, the heat-treatment affects the fatigue life. The S-N curves of both matrix specimen and butt weld specimen are reversed at some cycle by the existence or nonexistence of heat-treatment. The grinding on the bead makes the fatigue limit decrease in the all specimens. But the reinforcement removed, the fatigue limit increases at the high cycle. Also, this study investigates the fatigue life estimation by examining butt weld bead profiles. The butt weld beads, which are welded by semi-robot method, have non-uniform bead profiles described by $\theta,\;\rho$ and h. The stress concentration factors $K_t$, are changed by each different $\theta,\;\rho$ and h from 1.395 to 2.863. Hence, the sensitivity of $K_t$ is changed by each $\theta,\;\rho$ and h. As $\theta$ becomes lower and $\rho$ and h become higher, $K_t$ increases. The fatigue life can he estimated very closely for the AAY specimens without residual stress using only butt weld bead profiles. But, fur the AAN specimens with residual stress, the fatigue life must be estimated by considering both the weld bead profiles and the residual stress data.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.20 no.2
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• pp.137-142
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• 1984

An experimental study has been performed on the heat transfer characteristics of condensation by the injecting steam flow in the tube. The comparison between results of experimental data and available data concerning equivalent Reynolds number has studied. As the result, the followings were obtained. 1. The shear stress of the radial direction in the tube when the injecting steam flow was condensed can be written as root($\tau$sub(0)/$\tau$sub(0v))=1+1.46X sub(tt) super(0.20). 2. The effect of the heat transfer in the injecting steam flow was less than the value of equivalent Reynolds number. The reason are the nonuniform fluid film of the axial and radial direction in the tube. 3. The value of N sub(u) by the heat transfer of condensation can be written as N sub(u)=1.08$\times$[{$\rho$ sub(l) d/$\mu$ sub(l)}/{$\delta$+(2.5/P sub(rl)) ln(y sub(i)/$\delta$)}]$\times${$\tau$ sub(0)/ $\rho$ sub(l)} super(1/2).

• BMB Reports
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• v.50 no.6
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• pp.335-340
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• 2017

Although doxorubicin (Dox)-induced oxidative stress is known to be associated with cytotoxicity, the precise mechanism remains unclear. Genotoxic stress not only generates free radicals, but also affects actin cytoskeleton stability. We showed that Dox-induced RhoA signaling stimulated actin cytoskeleton alterations, resulting in central stress fiber disruption at early time points and cell periphery cortical actin formation at a later stage, in HeLa cells. Interestingly, activation of a cofilin phosphatase, chronophin (CIN), was initially evoked by Dox-induced RhoA signaling, resulting in a rapid phosphorylated cofilin turnover leading to actin cytoskeleton remodeling. In addition, a novel interaction between CIN and $14-3-3{\zeta}$ was detected in the absence of Dox treatment. We demonstrated that CIN activity is quite contrary to $14-3-3{\zeta}$ binding, and the interaction leads to enhanced phosphorylated cofilin levels. Therefore, initial CIN activation regulation could be critical in Dox-induced actin cytoskeleton remodeling through RhoA/cofilin signaling.