• International Journal of Advanced Culture Technology
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• v.9 no.4
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• pp.409-416
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• 2021

We are invented the movement composition technique that is to check the food adjacent-package status of the wireless-management movement monitoring level (WMMML) on the movement monitoring communication system. The movement monitoring level condition by the movement monitoring communication system is formatted with the adjacent-package system. As to inspection a wireless RFID of the wireless RFID, we are found of the movement value with wireless RFID by the adjacent upper take form. The concept of movement monitoring level is formatted the reference of wireless-management level for composition signal by the movement package communication system. Further symbolizing a food composition of the WMMML of the medium-minimum in terms of the adjacent-package communication system, and the movement wireless RFID package that was the movement value of the far composition of the Mo-MMCS-FA-_φMED-MIN with 5.80±1.20 units, that was the movement value of the convenient composition of the Mo-MMCS-CO-_φMED-MIN with 4.06±(-0.04) units, that was the movement value of the flank composition of the Mo-MMCS-MO-_φMED-MIN with 0.91±0.07 units, that was the movement value of the vicinage composition of the Mo-MMCS-VI-_φMED-MIN with 0.18±(-0.03) units. The adjacent package will be to look into at the food ability of the adjacent-package communication system with wireless RFID by the movement monitoring level on the WMMML that is supply the wireless communication by the movement monitoring level system. We will be possible to make effort of a communication system by the management signal and to put to use of the delivery data of RFID level by the delivery system.

• Clinical and Experimental Pediatrics
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• v.65 no.4
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• pp.194-200
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• 2022

Background: Injury is the leading cause of death or disability in children and adolescents. Rates of deaths from injuries have recently declined, but studies of the occurrence of nonfatal injuries are lacking. Purpose: This study aimed to investigate nonfatal injuries in children and adolescents younger than 20 years based on data from the Korean National Health and Nutrition Survey, 2007-2018. Methods: A questionnaire survey was conducted to determine whether children and adolescents had experienced an injury requiring a hospital visit in the previous year. We investigated each injury's risk factors and characteristics. Results: Of a total of 21,598 children and adolescents, 1,748 (weighted percentage, 8.1%) experienced one or more injuries in the previous year. There was no yearly difference in the proportion of injuries experienced. Among the male subjects, 10.0% had an injury experience; among the female participants, 6.1% had an injury experience (P<0.001). The highest rate was 9.0% in children aged 1-4 years. In multivariate logistic regression analysis, male sex; having an urban residence; having restricted activity due to visual, hearing, or developmental impairment; and attention deficit/hyperactivity disorder were significant risk factors for injury experience. The characteristics of up to 3 injuries per patient were investigated, and 1,951 injuries were analyzed. Falls and slips accounted for 34.9%, collisions for 34.1%, and motor vehicle accidents for 11.3% of the total injuries. Ninety-six percent of injuries were unintentional, 20% caused school absences, and 10% required hospitalization. Conclusion: Among Korean children and adolescents, 8.1% experienced injuries at least once a year with no significant differences in incidence over the past 12 years. Greater attention and effort to prevent injuries are needed.

• Journal of Gastric Cancer
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• v.23 no.1
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• pp.224-249
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• 2023

Gastric cancer is heterogeneous in morphology, biology, genomics, and treatment response. Alterations in human epidermal growth factor receptor 2 (HER2) overexpression, microsatellite instability (MSI) status, programmed death-ligand 1 (PD-L1) levels, and fibroblast growth factor receptor 2 (FGFR2) can be used as biomarkers. Since the combination of fluoropyrimidine/platinum plus trastuzumab that was investigated in the ToGA trial was approved as a standard of care in HER2-positive patients in 2010, no other agents showed efficacy in the first- (HELOISE, LOGiC, JACOB trials) and second- (TyTAN, GATSBY, T-ACT trials) line treatments. Despite the success in treating breast cancer, various anti-HER2 agents, including a monoclonal antibody (pertuzumab), an antibody-drug conjugate (ADC; trastuzumab emtansine [T-DM1]), and a small molecule (lapatinib) failed to translate into clinical benefits until the KEYNOTE-811 (first-line) and DESTINY-Gastri01 (≥second-line) trials were conducted. The incorporation of HER2-directed treatment with immune checkpoint inhibitors in the form of a monoclonal antibody or ADC is now approved as a standard treatment. Despite the promising results of new agents (engineered monoclonal antibodies, bi-specific antibodies, fusion proteins, and small molecules) in the early phase of development, the management of HER2-positive gastric cancer requires further optimization to achieve precision medicine with a chemotherapeutic backbone. Treatment resistance is a complex process that can be overcome using a combination of chemotherapy, targeted agents, and immune checkpoint inhibitors, including novel agents. HER2 status must be reassessed in patients undergoing anti-HER2 treatment with disease progression after the first-line treatment. As a general guideline, patients who need systemic treatment should receive chemotherapy plus targeted agents, anti-angiogenic agents, immune checkpoint inhibitors, or their combinations.

• Journal of the Korean Society of Clothing and Textiles
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• v.47 no.4
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• pp.646-665
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• 2023

This study attempted to examine the characteristics of fashion cross-border e-commerce(CBEC) by analyzing about 35.7 million cases of customs clearance data received from the Korea Customs Service. The demographic characteristics of consumers and the features of products purchased from 2019 to 2021 were explored. Next, the association rules between products, brands, and websites were analyzed by men and women in their 20s to 50s. The results are as follows. First, women purchased more clothing products than men, and overall, consumers tended to purchase products at low prices every year. Second, the most commonly purchased products were T-shirts, bags, and other shoes. In the list clearance, the purchase frequency of international open markets increased for three years; in general clearance, the proportion of luxury brands was high every year. Finally, in the list clearance, the relationships between bags, other shoes, pants, and overseas open markets were significant, while the relationships between wallets, bags, and luxury brands were significant in general clearance. Based on this study, domestic companies participating in or competing against the CBEC market can develop appropriate strategies for merchandising and sourcing clothing products.

• Journal of muscle and joint health
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• v.16 no.1
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• pp.46-54
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• 2009

Purpose: The purpose of the study was to compare the effects of the Tai Chi self-help program with a self-help program on pain, stiffness, physical functioning, and fear of falling in women with osteoarthritis. Method: Total of 82 women with Osteoarthritis recruited from outpatient clinics or community health centers were randomly assigned either to a Tai Chi self-help group or a self-help group. Thirty subjects in the Tai Chi self-help group and 39 in the self-help group completed posttest measures(pain, stiffness, physical functioning, and fear of falling) at 6 months. Results: After the 6 month study period, the subjects in the Tai Chi self-help group reported significantly less difficulties in performing daily activities(mean difference=-0.16 vs. 6.19 for the self-help), and less fear of falling(mean difference=-3.20 vs. 0.27 for the self-help) than those in the self-help group. There were no significantly differences in pain and stiffness between the groups. Conclusion: The Tai Chi combined with self-help program was more effective than the self-help only program in reducing difficulties in performing daily activities and fear of falling in women with Osteoarthritis. Whether these changes prevent fall episodes requires further study.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.169-174
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• 2023

The purpose of this study is to analyze Korean college students' perceptions of interactions and senses of community, among students, and instructors and students as they took face-to-face classes by the time students and instructors came back to the classroom. Forty-nine college students participated in the study, and all of them had experienced non-face-to-face classes during the last two years from 2020 through 2021. They responded to the revised Rovai (2002)'s Classroom Community Scale (CCS), and the data were analyzed using a frequency analysis. The findings of data analysis showed that the students positively perceived the class contents and teaching formats of face-to-face classes, in terms of understanding and concentration on the class. On the other hand, it was found out that the students would still need more time for being familiar with face-to-face classes, and their affective variables of the educational environment should be considered.

• Physical Therapy Korea
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• v.29 no.2
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• pp.147-155
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• 2022

Background: Although various conventional approaches have been employed to reduce spasticity in neurological rehabilitation, only a few studies have shown scientific evidence for its effectiveness. Thus, we introduced a different concept (Ueda method) of rehabilitation therapy that can complement the limitations of conventional therapy. Objects: This study aimed to investigate the immediate effects of the application of the Ueda method on patients with spasticity after stroke via an electrophysiological study. Methods: We conducted a randomized double-blind pilot study in two rehabilitation hospitals involving 30 stroke patients who were randomly allocated to the Ueda (n = 15) and convention (n = 15) groups. Electromyographic data of six examined muscles in both upper extremities of all patients were recorded. The A-ApA index and activation ratios of upper extremity muscles were evaluated and compared between the groups to confirm post-intervention changes in upper-extremity flexor spasticity and flexion synergies. Repeated-measures analysis of variance was conducted to confirm the therapeutic effect (2 × 2) as a function of group (Ueda vs. convention) and time (pre-/post-intervention) on all outcome measures (p < 0.05). Results: In the Ueda group, the mean A-ApA index values differed significantly before and after the intervention (p = 0.041), indicating a weak evidence level; however, the effect size was medium (d = -0.503). The interaction effects of the A-ApA index between the Ueda and convention groups and between pre-intervention and post-intervention stages were significant (p = 0.012). The effect size was large (n_p² = 0.220). In the Ueda group, the activation ratios of the anterior deltoid fiber significantly decreased after the intervention in all reaching tasks. Conclusion: The Ueda method reduces upper-extremity flexor spasticity and changes its synergy in stroke patients and should be considered a rehabilitation therapy for spastic stroke patients.

• Journal of Ginseng Research
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• v.47 no.4
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• pp.593-603
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• 2023

Background: Korean Red Ginseng is a major source of bioactive substances such as ginsenosides. Efficacy of red ginseng extract (RGE), which contains not only saponins but also various non-saponins, has long been studied. In the water-soluble component-rich fraction of RGE (WS), a byproduct generated in the process of extracting saponins from the RGE, we identified previously unidentified molecules and confirmed their efficacy. Methods: The RGE was prepared and used to produce WS, whose components were isolated sequentially according to their water affinity. The new compounds from WS were fractionized and structurally analyzed using nuclear magnetic resonance spectroscopy. Physiological applicability was evaluated by verifying the antioxidant and anti-inflammatory efficacies of these compounds in vitro. Results: High-performance liquid chromatography confirmed that the obtained WS comprised 11 phenolic acid and flavonoid substances. Among four major compounds from fractions 1-4 (F1-4) of WS, two compounds from F3 and F4 were newly identified in red ginseng. The analysis results show that these compound molecules are member of the maltol-structure-based glucopyranose series, and F1 and F4 are particularly effective for decreasing oxidative stress levels and inhibiting nitric oxide secretion, interleukin (IL)-1β and IL-6, and tumor necrosis factor-α. Conclusion: Our findings suggest that a few newly identified maltol derivatives, such as red ginseng-derived non-saponin in the WS, exhibit antioxidant and anti-inflammatory effects, making them viable candidates for application to pharmaceutical, cosmetic, and functional food materials.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.322-322
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• 2022

Hay and haylage as forage are increasing in preference for cattle feed. Triticale (X Triticosecale Wittmack) is growing up as a forage crop due to its high production and feed value in South Korea. It is difficult to determine the harvesting stage of triticale for producing hay or haylage with the highest forage value and quality because feed and nutritional value by growth stages of triticale were not known in South Korea yet. In this study, we analyzed forage values, pH, and contents of organic acid, to confirm feed value and quality by growth stages of triticale. The triticale 'Joseong' was sown in the spring of 2022. The sample was prepared in 5 stages: seedling stage, booting stage, heading stage, 10 days after heading, and 20 days after heading. The triticale was dried under 10% and to about 50% moisture for hay and haylage respectively, and then both triticales were fermented anaerobically at room temperature for 40 days. The pH value in all hay and haylage became lower as the triticale was grown up, although the pH value of all triticale hays and haylages ranged between 7.05-5.68. The content of lactic acid in all triticale hays was almost meaningless. The contents in the haylage of the seedling stage were the highest (2.39%) among the haylages, even though those of 20 days after the heading stage (1.67%) were the lowest, which showed a similar tendency with pH value. Conclusionally, the results implied that the feed value and quality of triticale haylage were affected by harvesting time but not hay.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.144-144
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• 2022

The amount of required forage is increasing by 20% every year in South Korea, but the cultivation area for forage production is limited. The yield ability of triticale forage is the highest among the winter forage crops including rye and the crop has cold tolerance within the average low temperature of -10℃ in January. Therefore, this study analyzed effects of sowing and harvesting times on feed value and quality for efficiently using and supplying triticale as livestock feed. Seed of the triticales, 'Joseong' was sown in 2021 fall (October) and 2022 spring (March). The triticales were harvested according to growth stages: seedling stage, booting stage, heading stage, 10 days after heading, and 20 days after heading. Moisture contents of each harvested triticales were adjusted to about 60%, and then the triticales were fermented for 40 days at room temperature under anaerobic conditions as silage. We have analyzed pH and organic acid to determine the feed value and quality of each silage. The contents of lactic acid in silage ofthe triticale harvested at the seedling stage of both fall and spring-sown (1.61%, 1.63%) were the highest among all of the silages; the booting stage (0.75%, 1.33%), the heading stage (0.50%, 0.69%), 10 days after the heading stage (0.31%, 0.42%), and 20 days after heading stage (0.22%, 0.40%). Such as the contents of lactic acid in the silages, and the pH value of the silages The pH value in both the fall- and spring-sown became lower as the triticale was grown up: seedling stage (7.05, 6.85), booting stage (6.21, 6.75), heading stage (6.18, 6.28), 10 days after heading stage (6.22, 6.17), and 20 days after heading stage (6.15, 5.81). Taken together, the results showed that the feed value and quality of triticale silage were more affected by harvesting time than sowing time.