• Childhood Kidney Diseases
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• v.15 no.1
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• pp.38-48
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• 2011

Purpose: Focal segmental glomerulosclerosis (FSGS) is the most common glomerulopathy causing pediatric renal failure. Since specific treatment targeting the etiology and pathophysiology of primary FSGS is yet elusive, the authors explored the pathophysiology of FSGS by transcriptome analysis of the disease using an animal model. Methods: FGS/kist strain, a mouse model of primary FSGS, and RFM/kist strain, as control and the parent strain of FGS/kist, were used. Kidney tissues were harvested and isolated renal cortex was used to extract mRNA, which was run on AB 1700 mouse microarray chip after reverse transcription to get the transcriptome profile. Results: Sixty two genes were differentially expressed in FGS/kist kidney tissue compared to the control. Those genes were related to cell cycle/cell death, immune reaction, and lipid metabolism/vasculopathy, and the key molecules of their networks were TNF, IL-6/4, IFN${\gamma}$, TP53, and PPAR${\gamma}$. Conclusion: This study confirmed that renal cell death, immune system activation with subsequent fibrosis, and lipid metabolism-related early vasculopathy were involved in the pathophysiology of FSGS. In addition, the relevance of methodology used in this study, namely transcriptome profiling, and Korean animal model of FGS/kist was validated. Further study would reveal novel pathophysiology of FSGS for new therapeutic targets.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2007.04a
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• pp.149-152
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• 2007

The horizontal geo-location accuracy of KOMPSAT-2, without GCPs (Ground Control Points) is 80 meters CE90 for monoscopic image of up to 26 degrees off-nadir angle, after processing including POD (Precise Orbit Determination), PAD(Precise Attitude Determination) and AOCS (Attitude and Orbit Control Subsystem) sensor calibration. In case of multiple stereo images, without GCPs, the vertical geometric accuracy is less than 22.4 meters LE 90 and the horizontal geometric accuracy is less than 25.4 meters. There are two types of sensor model for KOMPSAT-2, direct sensor model and Rational Function Model (RFM). In general, a sensor model relates object coordinates to image coordinates The major objective of this investigation is to check and verify the geometrical performance when initial KOMPSAT-2 images are employed and briefly introduce the sensor model of KOMPSAT-2.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2004.04a
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• pp.337-343
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• 2004

Spatial information could be obtained from spaceborne high resolution optical and synthetic aperture radar(SAR) images. However, some satellite images do not provide physical sensor information instead, rational polynomial coefficients(RPC) are available. The objectives of this study are: (1) 3-dimensional ground coordinates were computed by applying rational function model(RFM) with the RPC for the stereo pair of Ikonos images and their accuracy was evaluated. (2) Interferometric SAR(InSAR) was applied to JERS-1 images to generate DEM and its accuracy was analysis. (3) Quality of the DEM generated automatically also analyzed for different types of terrain in the study site. The overall accuracy was evaluated by comparing with GPS surveying data. The height offset in the RPC was corrected by estimating bias. In consequence, the accuracy was improved. Accuracy of the DEMs generated from InSAR with different selection of GCP was analyzed. In case of the Ikonos images, the results show that the overall RMSE was 0.23327", 0.l1625" and 13.70m in latitude, longitude and height, respectively. The height accuracy was improved after correcting the height offset in the RPC. i.e., RMSE of the height was 1.02m. As for the SAR image, RMSE of the height was 10.50m with optimal selection of GCP. For the different terrain types, the RMSE of the height for urban, forest and flat area was 23.65m, 8.54m, 0.99m, respectively for Ikonos image while the corresponding RMSE was 13.82m, 18.34m, 10.88m, respectively lot SAR image.

• Korea Journal of Hospital Management
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• v.17 no.2
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• pp.21-33
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• 2012

Purpose : This study aims to suggest application of patients DB to hospital marketing by performing market segmentation and selecting target market. Consequently help to establish suited strategy of marketing. Method : 14,072 patients hospitalized in a University Medical Center were recruited into this study. In order to classify the customer groups, cluster analysis was used with RFM(Recency, Frequency, Monetary) model, and 1-way ANOVA verified the differences among groups. And then, sociodemographical status, healthcare utilization and diagnosis(ICD-10) of each group were compared to draw a marketing strategy. Results : Four groups were classified through clustering analysis, and'high use and high profit' and'low use and high profit' groups were selected as a target market. The features of target market were as follows, the female proportion was high; used a private room; hospitalized through the emergency room; had operation; length of stay was long; had many comorbidity and cooperative treatment. There was difference in each feature of target market: as for the'high use and high profit' group, many patients were diagnosed with 'certain infectious and parasitic diseases'; and as for the'low use and high profit'group, the proportion of patients who purchased'industrial accident compensation insurance'and'auto insurance'was relatively high; many patients were diagnosed with'Injury, poisoning and certain other consequences of external causes'. Conclusion : It is needed to establish'positioning' strategy by monitoring and communicating with'high use and high profit' group. And for the case of'low use and high profit' group, it is necessary to make a follow-up management and lead them to have a medical check-up.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.1 s.149
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• pp.1-11
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• 2006

The purpose of this study was to analyze the current CRM situation in Korean apparel industry. Specifically, research purposes were 1) to examine the concepts and benefits of CRM, 2) to examine CRM strategies, 3) to analyze CRM system(i.e., customer relationship management service, customer segmentation criteria, DB management system), and 4) to analyze the potential problems and CRM adoption plan. The subjects for this research were thirty CRM managers in Korean apparel firms classified by the company type(woman's wear, man's wear, casual wear, children's wear, retailer) interviewed from December 2003 to March 1004. The results of this study were as follows: First, the concept of CRM represented the prime customer relationship, continuous consideration, and customer management system. The benefits of CRM reflected re-sales, improvement of profit share, and acquisition of customer's data base. Second, concerning the CRM strategies, most companies focused on persistent customer management through mileage program, membership cards and also implemented product strategies such as demand forecasting, customization based on customer data analysis. We also found that industry preferred to use pricing strategies, for example, segmentation of customer through discrepancies of price in which customers are provided by discount and gift voucher services. Regarding distribution strategy, channel diversification, localized service, and convenient delivery system were used. As promotion strategies, they chose celebrating customers' personal events and promoting cultural events and issuing coupons. Third, regarding CRM system, information service was the most frequently adopted, important and highly beneficial category. Also POS/web-POS, homepage were main sources of information. RFM is the mostly commonly used customer segmentation criteria. Fourth, potential problems in CRM adoption were lack of CRM knowledge and performance measurement of CRM. Future CRM adoption plan included CRM education and development of CRM performance measures.

• Journal of Korean Society for Geospatial Information Science
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• v.18 no.4
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• pp.3-10
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• 2010

In this study, the orbit-based sensor modeling is applied to the digital plotting and the accuracy of digital plotting is analyzed. The KOMPSAT-2 satellite image with orbit-attitude model is used for the analysis. The precise sensor modeling with various combination of parameters is performed for the stereo satellite image. In addition, we analyze the error range of ground control points by applying the result of stereo modeling to digital survey system. According to the result, it is possible to produce digital map using stereo image with a small number of GCPs when the orbit-based sensor modeling for KOMPSAT-2 is applied. This means that it is suitable for the generation of digital map on a scale of 1/5,000 to 1/25,000 considering the resolution of KOMPSAT-2 image.

• Journal of the Korea Society of Computer and Information
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• v.19 no.2
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• pp.193-200
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• 2014

Due to the advent of ubiquitous computing environment, it is becoming a part of our common life style. And tremendous information is cumulated rapidly. In these trends, it is becoming a very important technology to find out exact information in a large data to present users. Collaborative filtering is the method based on other users' preferences, can not only reflect exact attributes of user but also still has the problem of sparsity and scalability, though it has been practically used to improve these defects. In this paper, we propose clustering method by user's features based on SOM for predicting purchase pattern in u-Commerce. it is necessary for us to make the cluster with similarity by user's features to be able to reflect attributes of the customer information in order to find the items with same propensity in the cluster rapidly. The proposed makes the task of clustering to apply the variable of featured vector for the user's information and RFM factors based on purchase history data. To verify improved performance of proposing system, we make experiments with dataset collected in a cosmetic internet shopping mall.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.891-899
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• 2024

The Fourth Industrial Revolution is centered on a personalized demand fulfillment economy and is all about transformation and flexible processing that can deliver what customers want in real time across space and time. This paper implements the construction and operation of a packaging platform that can instantly procure the required packaging products based on real-time orders and evaluates its performance. The components of customer satisfaction are flexible and dependent on the situation which requires efficient management of enterprise operational processes based on an e-SCM platform. An OMS optimized for these conditions plays an important role in maximizing and differentiating the efficiency of a company's operations and improving its cost advantage. OMS is a system of mass customization that provides efficient MOT(Moment of Truth) logistics services to meet the eco-friendly issues of many individual customers and achieve optimized logistics operation goals to enhance repurchase intentions and sustainable business. OMS precisely analyzes the collected data to support information and decision-making related to efficiency, productivity, cost and provide accurate reports. It uses data visualization tools to express data visually and suggests directions for improvement of the operational process through statistics and prediction analysis.