• Title/Summary/Keyword: REM Model

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Linalool Ameliorates Memory Loss and Behavioral Impairment Induced by REM-Sleep Deprivation through the Serotonergic Pathway

  • Lee, Bo Kyung;Jung, An Na;Jung, Yi-Sook
    • Biomolecules & Therapeutics
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    • v.26 no.4
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    • pp.368-373
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    • 2018
  • Rapid eye movement (REM) sleep has an essential role in the process of learning and memory in the hippocampus. It has been reported that linalool, a major component of Lavandula angustifolia, has antioxidant, anti-inflammatory, and neuroprotective effects, along with other effects. However, the effect of linalool on the cognitive impairment and behavioral alterations that are induced by REM-sleep deprivation has not yet been elucidated. Several studies have reported that REM-sleep deprivation-induced memory deficits provide a well-known model of behavioral alterations. In the present study, we examined whether linalool elicited an anti-stress effect, reversing the behavioral alterations observed following REM-sleep deprivation in mice. Furthermore, we investigated the underlying mechanism of the effect of linalool. Spatial memory and learning memory were assessed through Y maze and passive avoidance tests, respectively, and the forced swimming test was used to evaluate anti-stress activity. The mechanisms through which linalool improves memory loss and behavioral alterations in sleep-deprived mice appeared to be through an increase in the serotonin levels. Linalool significantly ameliorated the spatial and learning memory deficits, and stress activity observed in sleep-deprived animals. Moreover, linalool led to serotonin release, and cortisol level reduction. Our findings suggest that linalool has beneficial effects on the memory loss and behavioral alterations induced by REM-sleep deprivation through the regulation of serotonin levels.

Determination of Self Diffusion Distributions of Molten Polyurethanes by Relaxation Spectra (용융 폴리우레탄의 완화 스펙트럼에 의한 자체확산분포 결정)

  • Kim, Nam-Jeong
    • Journal of the Korean Chemical Society
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    • v.50 no.3
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    • pp.196-202
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    • 2006
  • The self diffusion distributions of viscoelastic molten polyurethanes were determined from the relationship between the relaxation spectra and the distribution of self diffusion. The relaxation spectra of ester, PCL and PCL dyed type molten polyurethanes were obtained by applying the experimental stress relaxation curves to the theoretical equation of the Ree-Eyring and Maxwell non-Newtonian model(REM model) from computer calculation. The experiments were carried out at various temperatures using the physica rheometer with the temperature controller. The self diffusion and hole distance of amorphous region of polyurethane samples were investigated by experiments of stress relaxation. The diffusion coefficients and hole volumes were calculated from rheological parameters and crystallite size in order to study the diffusion of flow segments in amorphous region. It was observed that the relaxation spectra and self diffusions of these polymer samples are directly related to the distribution of molecular weights, viscosities, hole volumes and activation energies of flow segments.

A Study on the Effect of Specimen Size using Resistivity Estimation Model (비저항추정모델을 이용한 실험체 크기의 영향에 대한 연구)

  • Lim, Young-Chul
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.23 no.6
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    • pp.113-119
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    • 2019
  • This study aims at the analysis using the Resistivity Estimation Model (REM) to examine the effect of specimen size on the measurement of electrical resistivity. In the experiment, specimens of concrete were fabricated and the apparent resistivity was measured for each electrode interval. The apparent resistivity measured was found to be distorted in the apparent resistivity as the specimen size became smaller and closer to the outside (edge). As a result of comparing the experimental and analysis values, it is expected that REM can be used to examine the effect of the size of the specimen.

pH Effect on Relaxation Spectra of Poly(methyl acrylate)-Poly(acrylonitrile) Copolymers by REM Model (REM 모델에 의한 Poly(methyl acrylate)-Poly(acrylonitrile) 공중합체 완화스펙트럼의 pH 영향)

  • Kim, Nam Jeong
    • Polymer(Korea)
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    • v.37 no.2
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    • pp.135-140
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    • 2013
  • The stress relaxation of poly(methyl acrylate)-poly(acrylonitrile) copolymer samples was carried out in air, distilled water, pH 3, 7 and 11 solutions at various temperatures using a tensile tester equipped with a solvent chamber. The relaxation spectra of poly(methyl acrylate)-poly(acrylonitrile) copolymers were obtained by applying the experimental stress relaxation curves to the equation of relaxation spectrum derived from the Ree-Eyring and Maxwell model. The determination of relaxation spectra was performed from computer calculation using a Laplace transform method. It was observed that the relaxation spectra of these samples are directly related to the distribution of molecular weights and self-diffusions of flow segments.

A Study on Earnings Management in Companies Achieving Sustainability: Accruals-based and Real Earnings Management

  • JI, Sang-Hyun;OH, Han-Mo;YOON, Ki-Chang;AN, Sang-Bong
    • Journal of Distribution Science
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    • v.17 no.9
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    • pp.103-115
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    • 2019
  • Purpose - We attempted to verify the level of ethics of firms achieving sustainable management from the aspect of reliability of accounting information. Specifically, we evaluated the effects of sustainable management on accruals-based earning management (AEM) and real earning management (REM). Research design, data, and methodology - We employed the issuance of sustainability reports in addition to the indices of social responsibility and environmental-management evaluation of the Korea Corporate Governance Service in order to measure sustainability management. AEM was measured using discretionary accruals and calculated using the operant Jones model. Specifically, REM was measured using the methodology suggested by prior studies. The sample of our study consisted of 1,418 years of public listed firms in the Korea Stock Exchange from 2015 to 2017. Results - First, the level of AEM in firms achieving sustainable management was lower than the other. Second, the level of REM in these firms was lower than the other. Nonetheless, another analysis showed that the level of governance control affects the level of earning management and that the levels of AEM and REM were generally lower in firms achieving sustainable management than the others. Conclusions - We expected that firms achieving external ethics tend to have a higher level of internal ethics than others.

Factors Affecting Real Earning Management: Evidence from Indonesia Stock Exchange

  • SIAHAYA, Septina Louisa;SANDANAFU, Sally Paulina;APONNO, Chrestiana;SADUBBUN, Vury Lilian Angela
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.8
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    • pp.85-91
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    • 2021
  • This research aims to analyze the impact of Financial Risk (FR), Information Asymmetric (IA), and Earning Power (EP) on Real Earning Management (REM) of listed trading companies in IDX Indonesia. This study aims to analyze the influence of FR, IA, EP, on REM through Operating Cash Flow, Production expense, and Discretionary Expense. The study employs an unbalanced panel of data set from 2014 to 2018 on the activity of all trading companies (15 in total) as selected samples of 48 feasible samples from 144 existing data. The sample used a non probability sampling method with a purposive sampling technique. This research was classified as causative and tested by multiple linear regression model with cross-sectional analysis. The result indicated a significant impact of FR on REM through PROD and DISX but not through COF. How ever, IA, and EP showed significant impact on REM by means of COF but not go by PROD and DISX..The findings in this study contribute to the users of financial reports particularly the stakeholders in defining the determinants of real earning management practices among firms when it comes to decision making.

Estimating Indoor Radio Environment Maps with Mobile Robots and Machine Learning

  • Taewoong Hwang;Mario R. Camana Acosta;Carla E. Garcia Moreta;Insoo Koo
    • International journal of advanced smart convergence
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    • v.12 no.1
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    • pp.92-100
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    • 2023
  • Wireless communication technology is becoming increasingly prevalent in smart factories, but the rise in the number of wireless devices can lead to interference in the ISM band and obstacles like metal blocks within the factory can weaken communication signals, creating radio shadow areas that impede information exchange. Consequently, accurately determining the radio communication coverage range is crucial. To address this issue, a Radio Environment Map (REM) can be used to provide information about the radio environment in a specific area. In this paper, a technique for estimating an indoor REM usinga mobile robot and machine learning methods is introduced. The mobile robot first collects and processes data, including the Received Signal Strength Indicator (RSSI) and location estimation. This data is then used to implement the REM through machine learning regression algorithms such as Extra Tree Regressor, Random Forest Regressor, and Decision Tree Regressor. Furthermore, the numerical and visual performance of REM for each model can be assessed in terms of R2 and Root Mean Square Error (RMSE).

Absolute Position Estimation Algorithm Using Sequential Aerial Images (연속 항공영상을 이용한 절대위치 추정 알고리듬)

  • 심동규;박래홍
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.36S no.3
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    • pp.68-75
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    • 1999
  • 본 논문은 항공영상으로부터 REM( recovered elevation map)를 추출하여 DEM (digital elevation model)과 정합함으로써 비행체의 위치를 추정하는 기법을 제안하였다. 제안한 알고리듬은 연속항공영상을 이용함으로써 보다 넓은 지역에 대한 REM (recovered elevation map)복원이 가능하여 정합확률이 높아진다. 또한 강건한 거리 척도를 사용함으로써 몇 개의 점에서의 매우 큰 오차에 영향을 받지 않은 알고리듬을 제안하였다. 본 논문에선 몇 개의 항공영상을 가지고 컴퓨터 시뮬레이션을 통하여 제안한 알고리듬의 효용성을 보였다.

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Verification on PTF (Pedo-Transfer Function) estimating soil water retention based on soil properties (토양특성 기반 토양수분 함량 예측을 위한 PTF 적용성 검정)

  • Hur, Seung-Oh;Sonn, Yeon-Gyu;Hyun, Byung-Kewn;Shin, Kook-Sik;Oh, Taek-Keun;Kim, Jeong-Gyu
    • Korean Journal of Agricultural Science
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    • v.41 no.4
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    • pp.391-398
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    • 2014
  • Identifying soil water content as a major factor for evaluating irrigation and water resource is a primary module to develop a prediction model. A variety of PTFs (Pedo-Transfer Functions) are applied in the models to estimate soil water content, the analysis techniques, however, which compare the estimated from models and the measured by instruments, are not reached at the level to demonstrate the effectiveness of the PTFs in Korea. Many soil physicians such as Eom, Peterson, Rawls, Saxton, Bruand, Baties, Tomasella & Hodnett (T&H), and Minasny, have developed analytic models using PTFs. Soil data for the analysis used soil water contents on 347 soil series (10 kPa), 358 soil series (33 kPa), 356 soil series (1,500 kPa) established by NAAS (National Academy of Agricultural Science). A coefficient of determination on soil water content at 10, 33 and 1,500 kPa was the highest as 0.5932 in EM (Eom model), 0.6744 in REM (Rawls model) and 0.6108 in REM, respectively. In conclusion, it is strongly suggested that the use of EM or REM is suitable for estimating soil water content in Korea although SM (Saxton model) has been widely used.

Risk Evaluation Based on the Hierarchical Time Delay Model in FMEA (FMEA에서 계층적 시간 지연 모형에 근거한 위험평가)

  • Jang, Hyeon Ae;Lee, Min Koo;Hong, Sung Hoon;Kwon, Hyuck Moo
    • Journal of Korean Society for Quality Management
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    • v.44 no.2
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    • pp.373-388
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    • 2016
  • Purpose: This paper suggests a hierarchical time delay model to evaluate failure risks in FMEA(failure modes and effects analysis). In place of the conventional RPN(risk priority number), a more reasonable and objective risk metric is proposed under hierarchical failure cause structure considering time delay between a failure mode and its causes. Methods: The structure of failure modes and their corresponding causes are analyzed together with the time gaps between occurrences of causes and failures. Assuming the severity of a failure depends on the length of the delayed time for corrective action, a severity model is developed. Using the expected severity, a risk priority metric is defined. Results: For linear and quadratic types of severity, nice forms of expected severity are derived and a meaningful metric for risk evaluation is defined. Conclusion: The suggested REM(risk evaluation metric) provides a more reasonable and objective risk measure than the conventional RPN for FMEA.