• Title/Summary/Keyword: RDS

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Pediatric RDS classification method employing segmentation-based deep learning network (영역 분할 기반 심층 신경망을 활용한 소아 RDS 판별 방법)

  • Kim, Jiyeong;Kang, Jaeha;Choi, Haechul
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2022.06a
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    • pp.1181-1183
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    • 2022
  • 신생아 호흡곤란증후군(RDS, Respiratory Distress Syndrome)은 미숙아 사망의 주된 원인 중 하나이며, 이 질병은 빠른 진단과 치료가 필요하다. 소아의 x-ray 영상을 시각적으로 분석하여 RDS 의 판별을 하고 있으나, 이는 전문의의 주관적인 판단에 의지하기 때문에 상당한 시간적 비용과 인력이 소모된다. 이에 따라, 본 논문에서는 전문의의 진단을 보조하기 위해 심층 신경망을 활용한 소아 RDS/nonRDS 판별 방법을 제안한다. 소아 전신 X-ray 영상에 폐 영역 분할을 적용한 데이터 세트와 증강방법으로 추가한 데이터 세트를 구축하며, RDS 판별 성능을 높이기 위해 ImageNet 으로 사전학습된 DenseNet 판별 모델에 대해 구축된 데이터 세트로 추가 미세조정 학습을 수행한다. 추론 시 입력 X-ray 영상에 대해 MSRF-Net 으로 분할된 폐 영역을 얻고 이를 DenseNet 판별 모델에 적용하여 RDS 를 진단한다. 실험결과, 데이터 증강과 폐 영역을 분할을 적용한 판별 방법이 소아전신 X-ray 데이터 세트만을 사용하는 것과 비교하여 3.9%의 성능향상을 보였다.

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Effects of ruminally degradable starch levels on performance, nitrogen balance, and nutrient digestibility in dairy cows fed low corn-based starch diets

  • Luo, Guobin;Xu, Wenbin;Yang, Jinshan;Li, Yang;Zhang, Liyang;Wang, Yizhen;Lin, Cong;Zhang, Yonggen
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.5
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    • pp.653-659
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    • 2017
  • Objective: This trial was performed to examine the effects of ruminally degradable starch (RDS) levels in total mixed ration (TMR) with low corn-based starch on the milk production, whole-tract nutrient digestibility and nitrogen balance in dairy cows. Methods: Eight multiparous Holstein cows (body weight [BW]: $717{\pm}63kg$; days in milk [DIM]: $169{\pm}29$) were assigned to a crossover design with two dietary treatments: a diet containing 62.3% ruminally degradable starch (% of total starch, low RDS) or 72.1% ruminally degradable starch (% of total starch, high RDS). Changes to the ruminally degradable levels were conducted by using either finely ground corn or steam-flaked corn as the starch component. Results: The results showed that dry matter intake, milk yield and composition in dairy cows were not affected by dietary treatments. The concentration of milk urea nitrogen was lower for cows fed high RDS TMR than low RDS TMR. The whole-tract apparent digestibility of neutral detergent fiber, acid detergent fiber and crude protein decreased, and that of starch increased for cows fed high RDS TMR over those fed low RDS TMR, with no dietary effect on the whole-tract apparent digestibility of dry matter and organic matter. The proportion of urinary N excretion in N intake was lower and that of fecal N excretion in N intake was higher for cows fed high RDS TMR than those fed low RDS TMR. The N secretion in milk and the retention of N were not influenced by the dietary treatments. Total purine derivative was similar in cows fed high RDS TMR and low RDS TMR. Consequently, estimated microbial N flow to the duodenum was similar in cows fed high RDS TMR and low RDS TMR. Conclusion: Results of this study show that ruminally degradable starch levels can influence whole-tract nutrient digestibility and nitrogen balance in dairy cows fed low corn-based starch diets, with no influence on performance.

Genetic risk factors associated with respiratory distress syndrome

  • Jo, Heui Seung
    • Clinical and Experimental Pediatrics
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    • v.57 no.4
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    • pp.157-163
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    • 2014
  • Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS. The variance of the risk of RDS in various races/ethnicities or monozygotic/dizygotic twins has suggested genetic influences on this disorder. So far, several specific mutations in genes encoding surfactant-associated molecules have confirmed this. Specific genetic variants contributing to the regulation of pulmonary development, its structure and function, or the inflammatory response could be candidate risk factors for the development of RDS. This review summarizes the background that suggests the genetic predisposition of RDS, the identified mutations, and candidate genetic polymorphisms of pulmonary surfactant proteins associated with RDS.

Understanding and managing patients with adult rare diseases

  • Jangsup Moon
    • Journal of Genetic Medicine
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    • v.21 no.1
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    • pp.1-5
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    • 2024
  • Despite advances in the diagnosis and management of rare diseases (RDs), there remains a tendency to overlook adult RD patients. In addition to the considerable number of adult-onset RDs, advances in the diagnosis and management of pediatric RDs have led to an increase in the survival of these patients into adulthood. Adult RDs exhibit distinct features from pediatric counterparts, necessitating careful consideration during medical assessments. Given the extended life expectancy of adult RD patients, precise diagnosis and management strategies can significantly enhance patient outcomes. This review aims to provide an in-depth exploration of the characteristics unique to adult RDs. Special emphasis will be placed on the importance of cascade screening and prenatal genetic testing in the context of adult RDs, highlighting the need for a comprehensive understanding of these aspects in clinical practice.

Efficient method of Searching PI Code on RDS System (RDS System 에서의 효율적인 PI code 검출 기법에 관한 연구)

  • Cho, Chung-bum;Kim, Yound-cil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.112-115
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    • 2009
  • PI code searching method of RDS(Radio Data System) are unique method of maintain desired channel on moving machine like vehicle. Efficient and fast PI code search method are researching on the all of RDS related systems for both find more better channel before Original channel signal go to bad and find desired good signal quickly when get out of Weak signal Area. But Embedded system has limited environment like memory size, so It is very difficult to apply many well known PI code searching method. This thesis suggests simple and effective method of searching PI code, considering a Embedded System Environment.

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Clinical feature of neonatal pneumothorax induced by respiratory distress syndrome and pneumonia (호흡곤란증후군과 폐렴에 의한 신생아 기흉의 임상적 특성)

  • Jung, Ji-Sun;Park, Sang-Woo;Kim, Chun-Soo;Lee, Sang-Lak;Kwon, Tae-Chan
    • Clinical and Experimental Pediatrics
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    • v.52 no.3
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    • pp.310-314
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    • 2009
  • Purpose : Pneumothorax is an important factor responsible for increased mortality and morbidity in neonates. Here, we compared the clinical findings and prognosis for neonatal pneumothorax induced by respiratory distress syndrome (RDS) and pneumonia. Methods : Between January 2001 and December 2005, 80 patients with neonatal pneumothorax induced by RDS and pneumonia and admitted to the NICU of Dongsan Medical Center, Keimyung University, were enrolled. They were assigned to the RDS group (30 cases) or the pneumonia group (50 cases). Admission records for gestational age, onset day of life, rate of ventilatory care and thoracostomy, and prognosis were retrospectively reviewed and statistically analyzed for both groups. Results : The mean gestation age was significantly shorter in the RDS group (32.3 weeks) than in the pneumonia group (38.1 weeks) (P<0.001), and the mean onset day of life were later in the RDS group (4.6 days) than in the pneumonia group (1.8 days) (P<0.05). Rates of ventilatory care and thoracostomy were higher for the RDS group than for the pneumonia group (100% vs. 44%, and 66.7% vs. 48%, respectively). Total mortality rates and pneumothorax specific mortality rates were higher for the RDS group than for the pneumonia group (46.7% vs. 18%, P<0.01 and 33.3% vs. 16%, P<0.05, respectively). After logistic regression analysis, preterm significantly increased the mortality rate (OR 7.44, 95% CI: 1.99-27.86, P<0.005), but bilateral involvement (OR 1.17, 95% CI: 0.82-1.67, P>0.5) and the RDS group itself (OR 1.70, 95% CI: 0.52-5.54, P>0.3) did not increase mortality rates significantly. Conclusion : Our study suggests that neonatal pneumothorax in the RDS group tends to have a later onset, higher mortality rate, and needs a higher rate of thoracostomy than the pneumonia group. However, after logistic analysis, only preterm significantly and independently increased the mortality rate.

Heavy Metals in Road Deposited Sediments and Control of Them in Urban Areas: A Review (문헌고찰에 의한 도시 지역 도로퇴적물의 중금속 특성 및 적정 관리방안)

  • Kim, Do Gun
    • Land and Housing Review
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    • v.13 no.3
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    • pp.125-140
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    • 2022
  • Road Deposited Sediment (RDS) is the solids formed from the wear of road, wear of vehicles, exhausts, and the input of the emissions from various sources out of the roads. RDS is seriously polluted by organic matter, nutrients, and metals. RDS plays an important role as the sink and the transport medium of the associated pollutants because RDS can be carried to the adjacent water system via stormwater runoff. In this regard, the heavy metals in RDS were investigated based on the publications. The contents of the metals in RDS were highly variable. The concentration of Cr, Ni, Cu, Fe, Zn, As, Cd, and Pb in urban RDS in various regions was in a range of 3.16-3,410, 1.15-1,382, 20.2-9,069, 2,980-124,853, 81-2,550, 2.3-214, 0.19-21.3, and 15.21-1,125 mg/kg, respectively. The anthropogenic enrichment of the metals in RDS was confirmed by the high concentration of Cu, Zn, Cd, and Pb. The contents of the metals were higher in industrial and traffic areas than in residential areas, while they were generally increased with decreasing particle size. It is believed that this study's results would contribute to quantifying the metals' load via RDS and establishing control strategies.

Risk factors for respiratory distress syndrome in full-term neonates

  • Kim, Jin Hyeon;Lee, Sang Min;Lee, Young Hwan
    • Journal of Yeungnam Medical Science
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    • v.35 no.2
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    • pp.187-191
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    • 2018
  • Background: Respiratory distress syndrome (RDS) is a one of the most common cause of respiratory morbidity and mortality in neonates. This study was conducted to investigate the risk factors for RDS in full-term neonates. Methods: We conducted this retrospective study using medical records. The study group included 80 full-term neonates diagnosed with RDS and hospitalized in the neonatal intensive care unit between January 2012 and December 2016, at Yeungnam University Hospital. We analyzed sex, gestational age, birth weight, delivery method, maternal age, number of pregnancy, history of abortion, and complication of pregnancy. The control group included 116 full-time neonates who were hospitalized with jaundice during the same period. Results: The incidence of full-term RDS was more common in males (odds ratio [OR], 3.288; 95% confidence interval [CI], 1.446-7.479), cesarean section (OR, 15.03; 95% CI, 6.381-35.423), multiparity (OR, 4.216; 95% CI, 1.568-11.335). The other factors rendered no significant results. Conclusion: The risk factors for RDS in full-tern neonates were identified as male sex, cesarean section, and multiparity. Further studies involving more institutions are needed to clarify the risk factors for RDS in full-term infants.

Assessment of Particle Size Distribution and Pollution Impact of Heavy metalsin Road-deposited Sediments(RDS) from Shihwa Industrial Complex (시화산업단지 도로축적퇴적물의 입도분포 및 중금속 오염영향 평가)

  • Lee, Jihyun;Jeong, Hyeryeong;Ra, Kongtae;Choi, Jin Young
    • Journal of Environmental Impact Assessment
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    • v.29 no.1
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    • pp.8-25
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    • 2020
  • Industrialization has increased the production of road-deposited sediments (RDS) and the level of heavy metals in those RDS, which can have a significant impact on the surrounding aquatic environments through non-point pollution. Although the relationship between contamination characteristics and particle size of RDS is important for pollution control, there is very little information on this. In this study, we investigated the characteristics of grain size distribution and heavy metal concentrations in the road-deposited sediments (RDS) collected from 25 stations in Shihwa Industrial Complex. The environmental impact of RDS with particle size is also studied. Igeo, the contamination assessment index of each metal concentration, represents the RDS from Shihwa Industrial Complex are very highly polluted with Cu, Zn, Pb and Sb, and the levels of those metals were 633~3605, 130~1483, 120~1997, 5.5~50 mg/kg, respectively. The concentrations of heavy metals in RDS increased with the decrease in particle size. The particle size fraction below 250 ㎛ was very dominant with mass and contamination loads, 78.6 and 70.4%, respectively. Particles less than 125 ㎛ of RDS were highly contaminated and toxic to benthic organisms in rivers. RDS particles larger than 250 ㎛ and smaller than 250 ㎛ were contaminated by the surrounding industrial facility and vehicle activities, respectively. As a result of this study, the clean-up of fine particles of RDS, smaller than 125-250 ㎛, is very important for the control and reduction of non-point pollution to nearby water in Shihwa Industrial Complex.

Association between Maternal and Cord Blood Interleukin-10 (-819T/C and -592A/C) Gene Polymorphisms and Respiratory Distress Syndrome in Preterm Korean Infants (한국 미숙아 산모와 제대혈의 IL-10 유전자형 빈도와 신생아 호흡 곤란증 발생과의 연관성)

  • Park Eun-Ae;Cho Su-Jin;Kim Young-Ju;Park Hye-Sook;Ha Eun-Hee;Suh Young-Ju
    • Neonatal Medicine
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    • v.16 no.2
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    • pp.137-145
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    • 2009
  • Purpose: The aim of this study was to determine the genotype frequencies of interleukin 10 (IL-10) gene polymorphisms and to investigate their association with the risk of respiratory distress syndrome (RDS) in preterm Korean infants. Methods: Two hundred fourteen preterm infants born at Ewha Womans University Mok Dong Hospital between November 2003 and July 2008 were studied. The cord blood of preterm neonates and the corresponding maternal blood were analyzed by PCR for IL-10 gene (IL-10 -1082A/G, -819T/C, and -592A/C) polymorphisms. The clinical data of patients were collected retrospectively by chart review. Results: The genotype frequencies of IL-10 genes in Korean mothers with preterm infants differ from other reports. The prevalence of two promoter SNPs of the IL-10 cytokine gene was similar but none had the IL-10-1082GG homozygote. Multiple logistic regression analysis demonstrated the risk of RDS to be significantly lower in the infants of the mothers with an IL-10-592AC/CC genotype than in those with an AA genotype (P=0.033). The risk of RDS was significantly lower in the mother with an IL-10-819TC/CC genotype than in those with a TT genotype (P=0.030). However, IL-10 polymorphisms in the cord blood were not significantly different in preterm infants with RDS compared with the preterm infants without RDS. When we compared the incidence of RDS and each IL-10A-1082G/T-819C/A-592C haplotype, the ACC haplotype had a protective effect on RDS (P=0.007). Conclusion: We conclude that the maternal IL-10-592A/C and IL-10-819T/C polymorphisms may have a role in the development of the RDS in preterm infants.