• 척추신경추나의학회지
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• 제14권1호
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• pp.1-11
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• 2019

Objectives : The purpose of this study is to review clinical studies about the effect of chuna manual therapy (CMT) for peripheral facial paralysis in children. Methods : In this review, we searched 11 electronic databases (Pubmed, Cochrane Library, EMBASE, CINAHL, CAJ, Oasis, NDSL, KISS, RISS, KISTI, Dbpia); We concluded our literature search in April 23, 2019. We included only randomized controlled trials (RCTs) of testing CMT for peripheral facial paralysis in children. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. The meta-analysis was performed by synthesizing outcome data of total efficacy rate (TER). Results : After screening papers, a total of 6 RCTs were selected and analyzed. In the 6 RCTs, patients(n=15-60 per study) were randomized into groups for treatment and control. Specifically, the treatment group received CMT, while the control group was concurrently given usual care, such as acupuncture and medicine. The meta-analysis showed that the treatment group receiving CMT alone showed significant improvement in TER, compared to the control group receiving acupuncture therapy alone(P<0.05). And the treatment group receiving CMT combined with usual care showed positive results, in terms of TER, compared to the control group receiving usual care, but was not statistically significant(P>0.05). Conclusions : Our analysis suggests that CMT has therapeutic effects for peripheral facial paralysis in children. However, to confirm this result, further investigation accompanied by high quality studies is required.

• 재활치료과학
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• 제2권2호
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• pp.21-36
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• 2013

목적 : 본 연구의 목적은 뇌졸중 환자에서 로봇보조치료의 효과를 알아보기 위해 체계적 고찰을 통해 연구결과를 종합하고, 로봇보조치료에 관한 연구들을 비교하고 분석하고자 하는 것이다. 연구방법 : 2012년 6월부터 2012년 9월까지 외국학회지에 게재된 논문을 EMBASE, MEDLINE등을 통하여 검색하였다. 최종적으로 12개의 Randomized Controlled Trials(RCT) 논문을 대상으로 분석하였다. 결과 : 선정된 12편의 연구는 Pedro score 2~7점까지 다양했으며, 다양한 중재방법을 통하여 로봇보조치료의 효과를 극대화시키기 위한 연구들이 많았다. 주된 결과 측정도구로는 상지기능, 일상생활활동 수행능력을 평가하는 도구가 사용되었다. 로봇보조치료의 결과로는 상지기능과 일상생활활동 수행능력에서 향상을 보이나 로봇보조치료군과 고식적인 재활치료군 사이에 유의한 차이는 보이지 않았다. 결론 : 로봇보조치료는 뇌졸중 환자에게 그 효과를 극대화시키기 위해 다양한 중재방법으로 적용되고 있으며, 중재방법에 따라 효과의 차이가 나는 것으로 나타났다. 본 연구는 로봇보조치료의 임상적 적용에 대한 근거를 제시하며, 향후 연구에서는 다양한 중재방법을 적용하여 로봇보조치료의 효과를 극대화할 수 있는 방법에 대한 연구가 필요하다.

• Journal of Acupuncture Research
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• 제35권4호
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• pp.158-168
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• 2018

The purpose of this study was to review clinical studies of lumbar herniated intervertebral disc (LHIVD) treatment using acupuncture. Online database (PubMed, COCHRANE Library, EMBASE, CNKI, KISS, NDSL, KoreaMed, KMbase, OASIS, and KISTI) searches were conducted in May 2018. Studies that used acupuncture, electroacupuncture or warm needle acupuncture were included, along with participants who had lower back pain and radiating pain of their lower limbs consistent with radiological findings. Animal studies and nonclinical data were excluded. Data on treatment methods, site, time, frequency, period, and scales used were analyzed. There were 69 studies including 38 randomized controlled trials, 14 retrospective observational studies, and 17 clinical case studies. There were 51 acupoints selected for acupuncture treatment of LHIVD. The most frequently treated acupoints were BL23, BL25, BL24, and BL40. The mean treatment time, frequency, and duration were $26.06{\pm}6.70$ mins, $6.29{\pm}1.70$ times/week, and $20.57{\pm}11.04$ days, respectively, in randomized controlled trials (RCT), and $18.62{\pm}4.60$ mins, $11.58{\pm}3.99$ times/week, and $34.43{\pm}17.62$ days, respectively, in case/retrospective studies ($mean{\pm}SD$). This review collates information about acupuncture treatment methods for LHIVD.

• 대한한방부인과학회지
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• 제36권4호
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• pp.96-120
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• 2023

Objectives: This study reports the findings that support the efficacy of herbal medicine (HM) for premenstrual syndrome (PMS). Methods: We conducted meta-analysis of findings from randomized controlled trials (RCTs) for PMS treated with HM. The articles were published before July 2022, located using 9 databases (Pubmed, EMBASE, Cochrane Library, CINAHL, CNKI, CiNii, SCIENCE ON, KoreaMed, OASIS). Results: We observed 2,034 studies, of which 23 RCTs met our inclusion criteria. The risk of bias in the included studies was relatively unclear or high. Meta-analysis of 3 RCTs showed that HM group had a significantly higher total effective rate than the western medicine group (RR 1.20 [95% CI 1.06, 1.36, p=0.004]). Meta-analysis of 1 RCT showed that HM group had a significantly lower symptom score (MD -3.04 [95% CI -5.36, -0.72, p=0.01]), while there was no significant difference in daily record of severity of problems scale (MD -20.52 [95% CI -49.33, 8.29, p=0.16]). Conclusions: HM significantly improved PMS symptoms than general treatment and no serious adverse events were reported. However, the evidence on the effectiveness and safety of HM for PMS was not enough to provide reliable results due to the small number and low quality of included studies. We believe that rigorous RCTs will lead to more reliable evidence of the intervention.

• 동의신경정신과학회지
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• 제20권2호
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• pp.163-176
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• 2009

Objectives : To address most probable and suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on hwa-byung. Study Design : A systematic review of research studies of complementary and/or alternative medical(CAM) treatment of depression, and of domestic clinical trials of Traditional Korean Medicine, and of Chinese clinical trials of Traditional Chinese Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of depression intervening herbal medicine were searched through MEDLINE, Cochrane Library, and CNKI databases. Also, domestic RCTs intervening Traditional Korean Herbal Medicine were searched through Korean Traditional Knowledge Portal and Korean studies Information Service System(KISS). Studies were evaluated using Iadad scale and self-designed tool for this study. Results : Thirty four RCT studies( 10 from MEDLINE, 16 from CNKI, 8 domestic studies) of herbal medicine met inclusion criteria. Mean Jadad score of studies published in English was 2.8${\pm}$0.79, in Chinese 1.94${\pm}$0.77, and in Korean 2.75${\pm}$0.71. Twenty one percent of studies included pattern differentiation in their inclusion criteria. Twenty nine percent of studies used combined treatment of herbal and conventional medicine. Among studies on depression, 9% included Complementary Medical assessing tools. Conclusions : There is shortage of domestic clinical trial involving herbal medicine. In China, studies tend to focus on investigating effect of Combined treatment of herbal and conventional medicine on depression. Clinical trial(s) of hwa-byung should provide good internal validity by describing methodology for randomization, double-blinding, and attrition. Also, specific guideline for clinical trial, including Traditional Korean Medical aspects across inclusion criteria, and assessing tools is needed.

• 척추신경추나의학회지
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• 제10권1호
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• pp.1-14
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• 2015

Objectives : To evaluate the evidence supporting the effectiveness of Chuna manual therapy for functional dyspepsia. Methods : We conducted search across the 3 electronic databases (Pubmed, CAJ and Oasis) to find all of randomized controlled clinical trials(RCTs) that used Chuna manual therapy as a treatment for functional dyspepsia. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results : Thirteen RCTs met our inclusion criteria. The meta-analysis showed positive results for the use of Chuna manual therapy combined with medication treatments in terms of the efficacy rate when compared to medication treatments alone. Positive results were also obtained, in terms of the efficacy rate, when comparing Chuna manual therapy combined with medication plus specific electromagnetic therapy to medication treatments alone. Conclusions : Our systematic review found encouraging but limited evidence of Chuna manual therapy for functional dyspepsia. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend sham-controlled RCTs or comparative effectiveness research to test the effectiveness of Chuna manual therapy.

• 대한한방부인과학회지
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• 제24권4호
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• pp.105-113
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• 2011

Objectives: To examine the current status of clinical research in oriental medicine, and to assess 'risk of bias'(ROB) of randomized clinical trials(RCTs) in oriental medicine in Korea. Methods: Special committee for EBM, KOMS(Korean Oriental Medicine Society) reviewed 17 journals related to oriental medicine in Korea (from the first issue to May 2010), the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 2, 2010), and PubMed (1966 to May 2010). Then we selected eligible RCTs in terms of oriental medicine, and assessed 'risk of bias'. Results: We reviewed 12,653 articles from the 17 journals, and 41 articles from CENTRAL and PubMed. After non-clinical articles were excluded, 1,004 articles were left. Among them, the number of eligible studies in terms of oriental medicine was 306. In these eligible studies, 130 were RCTs. Of RCTs, 69 were on acupuncture, 25 on herbal medicine. The proportion of 'unclear' is high in the criteria of 'Allocation concealment', 'Blinding of participants and personnel', 'Blinding of outcome assessment' and 'Other bias'. On the other hand, 'low' has high in the criteria of 'Incomplete outcome data' and 'Selective reporting'. Conclusions: Risk of bias on oriental medicine is unclear in terms of 'allocation concealment' and 'blinding'. For high-quality research in oriental medicine, further research should be needed on randomization and blinding in the RCTs.

• 한국엔터테인먼트산업학회논문지
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• 제15권8호
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• pp.291-303
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• 2021

본 연구는 최근 증가하고 있는 시설거주 노인을 대상으로 건강문제로 보고되고 있는 우울과 수면장애에 대하여 웃음요법의 적용 효과를 확인하기 위한 연구이다. 이를 위해 시설거주 노인에게 웃음요법을 적용한 국내·외 실험연구들을 대상으로 체계적 고찰을 통해 연구 특성을 파악하고, 메타분석을 통해 우울과 수면장애에 대한 전체 효과크기와 중재 변인에 따른 효과크기를 파악하는 것을 목적으로 하고 있다. 최종 선정된 12편의 실험연구를 체계적으로 고찰하고 결과 변수에 영향을 미치는 전체 효과크기를 분석한 결과, 웃음요법은 시설거주 노인의 우울 감소에 유의한 효과가 있었으며, 수면장애 감소에는 유의한 효과가 없었다. 중재 변인에 따라 분석한 결과 웃음요법은 시행 횟수 10회 미만, 중재 소요 시간 400분 미만이나 400-1,000분 미만에서 우울 감소에 효과적이었다. 수면장애의 경우 전체 효과크기는 유의하지 않았으나 중재 소요 시간 300분 미만에서 수면장애 감소에 효과적이었다. 이러한 결과는 웃음요법이 시설거주 노인의 우울 감소에 효과적이며, 이를 적용할 때 시행 횟수와 중재 소요 시간과 같은 중재 변인을 고려하는 것이 필요함을 시사한다. 시설거주 노인의 수가 증가하고 있고, 우울과 수면장애와 같은 건강문제의 발생률이 증가하고 있는 점을 감안할 때 추후 연구에서 본 연구 결과를 토대로 시설거주 노인의 우울과 수면장애 감소를 위한 적용지침이 개발될 필요가 있다.

• 산업융합연구
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• 제21권8호
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• pp.97-110
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• 2023

이번 연구는 국내·외 만성폐쇄성폐질환 대상자에게 시행된 다양한 자가간호 중재 프로그램의 내용에 대한 연구결과를 통합하고 분석하기 위해 수행된 체계적 문헌고찰 연구이다. 문헌선정기준은 2000년 1월 1일부터 2022년 9월 30일까지로 PubMed, CINAHL, EMBASE, MEDLINE, RISS, DBpia, KISS 및 KMbase를 통해 검색된 무작위 대조군 실험연구로 사전-사후 설계를 적용한 논문을 채택하였다. 체계적 고찰에 포함된 연구는 총 23편으로 중재 관련 요인으로는 연구대상의 수, 중재자 유형, 중재 제공 횟수 및 기간, 중재효과 관련 요인으로는 중재효과 측정도구, 중재효과 변수 등을 분석하였다. 분석결과 만성폐쇄성폐질환 자가간호 중재 프로그램은 환자의 증상 악화 및 재입원을 예방에 도움이 될 수 있음을 확인하였다. 우리나라 만성폐쇄성폐질환자에게 적합한 자가간호 중재 프로그램 개발이 필요하며 환자의 접근성, 편의성 및 지속을 위한 동기 부여 방법 등을 고려한 중재 프로그램의 개발이 필요하다.

• Journal of Acupuncture Research
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• 제33권2호
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• pp.109-116
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• 2016

Objectives : Our primary objective lies in understanding the current landscape of translational research on acupuncture, moxibustion and pharmacopuncture. Methods : We searched our own selection of keywords of acupuncture, moxibustion and pharmacopuncture and translational research from three overseas databases (Pubmed, Scopus, Medicine) and four domestic databases (DBpia, KISS, Riss4u, Korea Med). Results : We have chosen 41 articles in total-40 articles on acupunture, 6 article on moxibustion(5 articles were duplicated in use in each category). Origin-wise, 48.8 %/24.8 %/17.0 % of our articles pool came from USA/China/Korea, respectively. UK, Austria, Thailand and Italy contributed the rest of our article pool. For those articles written in USA and China, review articles were the most common type. For the US articles, all 10 review articles were non-systematic reviews, while, for China's contribution, one out of 4 review articles were systematic review. Type-wise, our research pool's breakdown is as follows ; 17 review articles, 11 experimental research, 2 randomized controlled trials(RCT), 1 clinical trial, 4 conference reports, 1 letter, 1 study protocol and 4 uncategorized. Topic-wise, brain-neurology was most frequently referred with 8 articles, followed by parkinson's disease (3 articles) and epilepsy (2 articles). Conclusion : 1. In terms of research submission articles, Korea appears to be lacking translational research on acupuncture, moxibustion and pharmacopuncture, compared to USA and China, in our view. 2. Unlike the cases of USA and China, most of Korean translational research is limited to doing a T1 level of translational research. In order to bring bench-to-bedside to light. we believe, there should be more studies, and thereby a certain level of activation, to the T2 level of translational research in Korea. 3. Further, in our view there should be more efforts to improve article quality at the T1 level of translational research, which eventually becomes the fundamentals of the next level of research (i.e. T2 research), as well as to increase the number of research submissions, going forward.