• Proceedings of the Korean Radioactive Waste Society Conference
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• 2011.05a
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• pp.163-164
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• 2011

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2012.10a
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• pp.113-114
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• 2012

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2011.10a
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• pp.193-194
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• 2011

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2011.10a
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• pp.191-192
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• 2011

• Journal of Korea Multimedia Society
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• v.14 no.2
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• pp.210-218
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• 2011

Generally, GIS digital map has been represented and transmitted by ASCII and Binary data forms. Among these forms, Binary form has been widely used in many GIS application fields for the transmission of mass map data. In this paper, we present a hierarchical compression technique of polyline and polygon components for effective storage and transmission of vector map with various degree of decision. These components are core geometric components that represent main layers in vector map. The proposed technique performs firstly the energy compaction of all polyline and polygon components in spatial domain for the lossless compression of detailed vector map and compress independently integer parts and fraction parts of 64bit floating points. From experimental results, we confirmed that the proposed technique has superior compressive performance to the conventional data compression of 7z, zip, rar and gz.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.89-89
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• 2003

Exposure of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a variety of biological and toxicology effects, most of which are mediated by aryl hydrocarbon receptor (AhR). The ligand-bound AhR as a heterodimer with AhR nuclear translocator (ARNT) binds to its specific DNA recognition site, the dioxin-responsive element (DRE), and it results in increased transcription of CYP1A1 gene. Retinoic acid (RA) regulates the transcription of various genes for several essential functions through binding to two classes of nuclear receptors, the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Constitutive androstane receptor (CAR) also regulates the transcription of gene. In this study, we have examined how RAR, RXR and CAR regulated CYP1A1 in rainbow trout hepatoma cell (RTH 149) using luciferase reporter gene assay system. We did transient transfection with CYP1A1 luciferase reporter gene and treated with TCDD, all-trans RA, 9-cis RA and phenobarbital. Treatment of all-trans RA, 9-cis RA or phenobarbital decreased the TCDD induced transcription of CYP1Al. When we did transient cotransfection with CYP1A1 luciferase reporter gene and RXR, as increase of RXR concentration, the TCDD induced transcription of CYP1A1 was decreased. Transfection with CAR also decreased the TCDD induced transcription of CYP1A1 in RTH 149 cells.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.10a
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• pp.179-179
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• 2003

Exposure of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a variety of biological and toxicology effects, most of which are mediated by aryl hydrocarbon receptor (AhR). The ligand-bound AhR as a heterodimer with AhR nuclear translocator (ARNT) binds to its specific DNA recognition site, the dioxin-responsive element (DRE), and it results in increased transcription of CYP1A1 gene. Retinoic acid (RA) regulates the transcription of various genes for several essential functions through binding to two classes of nuclear receptors, the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Constitutive androstane receptor (CAR) also regulates the transcription of gene. In this study, we have examined how RAR, RXR and CAR regulated CYP1A1 in rainbow trout hepatoma cell (RTH 149) using luciferase reporter gene assay system. We did transient transfection with CYP1A1 luciferase reporter gene and treated with TCDD, all-trans RA, 9-cis RA and phenobarbital. Treatment of all-trans RA, 9-cis RA or phenobarbital decreased the TCDD induced transcription of CYP1A1. When we did transient cotransfection with CYP1A1 luciferase reporter gene and RXR, as increase of RXR concentration, the TCDD induced transcription of CYP1A1 was decreased. Transfection with CAR also decreased the TCDD induced transcription of CYP1A1 in RTH 149 cells.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.14 no.4
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• pp.41-54
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• 2011

Tree roots can enhance soil shear strength and slope stability. However, there has been a limited study about root reinforcement of major tree species in Korea because of some experimental difficulties. Thus, this study was conducted to analyze the performance of Japanese larch (Larix kaempferi) and Korean pine (Pinus koraiensis) which are two common plantation species in Korea. Profile wall method was used to measure the spatial distribution of root system and its diameter within 15 soil walls of Japanese larch stand and 13 soil walls of Korean pine stand in Taehwa University Forest, Seoul National University, Korea. Root tensile properties of each species were assessed in the laboratory, and root reinforcements were estimated by Wu model. The study observed that the number and cross-sectional area (CSA) of root in both species could tend to decrease with soil depth. Especially, CSA were well-fitted to exponential functions of soil depth. Mean root area ratios (RAR) were 0.03% and 0.10% for Japanese larch and Korean pine, respectively. Estimated root reinforcement from Wu model were, on the average, 4.04 kPa for Japanese larch and 12.26 kPa for Korean pine. Overall, it was concluded that root reinforcement increased the factor of safety (Fs) of slope for small-scale landslide as the result of two-dimensional (2-D) infinite slope stability analysis considering vegetation effects.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.531-535
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• 2015

본 연구에서는 한반도 관측 공백지역인 북한지역에 대하여 레이더와 위성 원격탐사자료를 활용하여 강수량과 토양수분 등 수문기상정보를 생산 및 검증하고 효율적인 수문 모니터링 및 수문 기상 재해 감시와 평가 방안을 수립하고자 한다. 또한, 북한지역의 수문 기상 정보 수집 및 통합 DB를 마련하고 북한 수문기상 포털시스템을 구축함으로써 부처 간 자료를 공유할 수 있는 매개체를 마련하여 일관된 정책 수립과 효율적인 물관리를 도모하고자 한다. WPMM(Window Probability Matching Method)방법을 기반으로 구성된 RAD-RAR(Rain rate system) 산정 알고리즘(Rosenfeld et al., 1993)을 활용하여 산출된 합성 강우장 데이터의 정확성을 비교 분석하기 위해 접경지역 AWS 강수량과 세계기상통신망(GTS)기반 강수량을 산출하여 각각 레이더 강수량과 검증분석을 실시하였다. 연구기간은 2012년과 2013년 여름철 기간 중 5개의 기간을 선별하였다. 연구 기간 동안의 RAR 합성 강우장 데이터를 이용하여, 기간 중 1시간 동안 누적된 강수량을 산출하고 접경지역 AWS 강수량과 비교하였고 12시간 누적 강수량을 산출하여 GTS 강수량과 비교 분석을 실시하였다. 전반적으로 레이더 강수량에 비해 AWS 강수량이 더 높게 나타났으며 마찬가지로 레이더 강수량과 GTS 강수량의 비를 통해 레이더 자료가 상대적으로 과소추정되고 있음을 확인 할 수 있었다. 미항공우주국(NASA)과 일본항공우주국(JAXA)을 중심으로 진행된 GPM(Global Precipitation Measurement)미션은 한 개의 핵심위성과 마이크로파 복사계를 탑재한 10여개의 보조위성으로 구성되어 있으며, 매 3시간 간격의 전구 강수량 자료 생산에 목적이 있다. 이는 홈페이지를 통해 Level 1, 2, 3의 GPM 데이터를 배포하고 있다. 특히 Level 2 데이터는 언급된 3시간 간격의 전구 강수량 데이터를 제공한다. 이 경우 복사량을 강수량으로 변환하는 번거로움을 덜 수 있으며 NASA가 제공하는 Panoply라는 프로그램을 이용하여 한반도 강수 자료 가시화가 가능하다.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8019-8026
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• 2014

The promyelocytic leukemia (PML) gene is a gene known to be a tumor suppressor, although recent data suggest that it has a dual function in tumorigenesis. It was initially discovered in acute promyelocytic leukemia (APL) in which a t(15; 17) chromosomal translocation fused it to the retinoic acid receptor alpha ($RAR{\alpha}$). It has been shown to be involved in various types of cancer. It has at least 6 nuclear isoforms and a cytoplasmic type with different characteristics. Its multiple functions in growth inhibition, apoptosis induction, replicative senescence, inhibition of oncogenic transformation, and suppression of migration and angiogenesis have made it a therapeutic target for cancer therapy. However, its dual role in the process of tumorigenesis has made this field challenging. In this review, we discuss PML structure, functions and expression in tumors.