• Journal of Food Hygiene and Safety
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• v.34 no.6
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• pp.519-525
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• 2019

The Ministry of Food and Drug Safety (MFDS) is amending its test methods for health functional foods (dietary food supplements) to establish regulatory standards and specifications in Korea. In this regard, we are continuing our research on analytical method development for the items listed in the Korean Health Functional Food Codex. In this study, we have developed a sensitive and selective test method that could simultaneously separate and determine coenzyme Q10 based on liquid chromatographic-tandem mass spectrometry (LC-MS/MS). Calibration curves showed linearity with a correlation coefficient (R²) of > 0.999 and the limits of detection (LODs) and limits of quantitation (LOQs) were in the range of 26.0 ㎍/L and 78.9 ㎍/L, respectively. The recovery results ranged between 98.6-107.0% at 3 different concentration levels with relative standard deviations (RSDs) less than 5%. The proposed analytical method was characterized with high resolution of the coenzyme Q10 and the assay was fully validated as well.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.4
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• pp.316-329
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• 2012

In this paper, optimum design process of ICP (Inductively Coupled Plasma) torch, which has been used widely in aerospace application, such as supersonic plasma wind tunnel, is presented. For this purpose, the behaviors of equivalent circuit parameters (equivalent resistance and inductance, coupling efficiency) were investigated according to the variations of torch design parameters (frequency, $f$, confinement tube radius, $R$ and coil turn numbers, $N$) in the basis of analytical and numerical MHD (Magneto Hydro-Dynamics) models combined with electrical circuit theory. From the results, it is found that equivalent resistance is increased with the increase of $f$ values but vice versa for equivalent inductance. For elevated values of $R$ and $N$, however, both parameters tend to increase. Based on these observations, ICP torch with a power level of 10 kW can be optimized at the design ranges of $f$=4~6 MHz, $R$=17~25 mm and $N$=3~4 to maximize the electrical coupling efficiency, which is the ratio of equivalent resistance to equivalent inductance.

• The Journal of Society for e-Business Studies
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• v.24 no.3
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• pp.73-86
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• 2019

After the 4th industrial revolution, the healthcare industry is striving to find new business models through new technologies. Among them, blockchain technology is one of the technologies that have great interest in the healthcare industry. Most providers of personal health record systems have difficulty in securing marketability due to various problems. Therefore, they try to integrate blockchain technology to develop new systems and gain marketability. However, blockchain has limitations in solving the problems of the personal health record system. In this study, we have designed a personalized health data management framework that enables information subjects to acquire full ownership rights of individual's health data, based on distributed ledger technology. For the framework design, we refer to the structure of R3 Corda. It was designed with a different network structure than the existing blockchain systems so that the node can be operated on the personal user's mobile device. This allows information subjects to directly store and manage their own data and share data with authorized network members. Through the proposed system, the information utilization of the healthcare industry can be improved and the public health promotion and medical technology development can be realized.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.26 no.5
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• pp.416-423
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• 1993

Fish sauces prepared from sardine, Sardinops melanosticta were tested for inhibitory activity against angiotensin-I converting enzyme(ACE). Three kinds of fish sauces were prepared from scrap(S), meat(M) and round(R) of sardine, respectively. ACE inhibitory activity of sardine sauce S and R decreased with the elapse of fermentation period, whereas that of sardine sauce M increased to 30 days and thereafter decreased. ACE inhibitory activity of sardine sauce M fermented with koji was higher than that without koji. And occurrence of $5\%$ TCA soluble peptide-nitrogen was similar to tendancy of the ACE inhibitory activity. The ACE inhibitory activity increased with an increment of amounts added and was stable at heat treatment in boiling water bath for 5hrs. $IC_{50}\%$ (Amounts of inhibitors need for $50\%$ inhibition) of the sardine sauce S, M and R fermented with(without) koji during 90 days was $125{\mu}g(140{\mu}g),\;200{\mu}g(100{\mu}g)$ and $125{\mu}g(135{\mu}g)$, respectively. From the profiles of fractionation of the sardine sauce R fermented without koji for 90 days, the molecular weight of most active fraction was about 1,400 and the amino acids of Glu, Ala, Leu and Lys were found in abundance.

• Journal of Bio-Environment Control
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• v.21 no.3
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• pp.170-179
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• 2012

We examined pretreatment methods eliminating potassium and sodium efficiently for coir bag used in hydroponics by analyzing drainage coming from coir bags. In the first experiment we investigated for six coir bags with the high market shares. The three types of pretreatment were washing coir bags with only water for 7 days (W7S0), washing with water for 4 days and further with nutrient solution for 3 days (W4S3), and washing with only nutrient solution for 7 days (W0S7). In the second experiment we tested reproducibility of the experiment results for Bio Grow and coco Mix among six coir bags used in the first experiment to verify the results. As a result, the best pretreatments for the pH stabilization were W4S3 and W0S7. The EC value of the drainage was stabilized to less than 1.0 that is the same as EC of the supply solution on the fourth day in all treatments. The nutrients of the drainage in W7S0 was stabilized in 3~4 days but calcium and magnesium were depleted. We assessed that washing longer than 4 days was waste of water. The stabilization of coir bags in W0S7 was similar to it in W4S3, but washing with the nutrient solution for 7 days seemed to be uneconomical. The reproducibility experiment for two coir bags ensured the results in the first experiment. Therefore, the pretreatment method, which is the most simple to implement and economic, seems to wash with water for 3 days and then with the nutrient solution for 1 day before planting on coir bag.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.3
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• pp.283-288
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• 2011

Since minerals are in ionic forms in aqueous phase (like deep sea water), it is very hard to incorporate concentrated minerals in gel like cosmetic formulations which are generally composed of carbomer or acrylates polymer. In this study, we invented a salt-resistant network formulation made of silicon copolyol. It was found that the network formulation traps minerals (especially from marine) in a mesh-like silicone copolyol structure. Since the mineral-containing formulation makes a very thin film on the skin, minerals could be easily absorbed into stratum corneum. In 6 weeks in vivo test, it was found that the novel mineral formulation increased the amounts of amino acids, major components of natural moisturizing factors (NMFs), as well as levels of minerals. It was also found that the moisture contents and the brightness of the skin increased.

• Korean Journal of Food Science and Technology
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• v.42 no.6
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• pp.699-704
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• 2010

Rapeseed oil was stored under different conditions such as in the dark, with UV treatment, and with prooxidantscytochrome C and copper ion. The rapeseed oils stored at different temperatures were analyzed by a mass spectrometrybased electronic nose and discriminant function analysis (DFA). Volatile components in the rapeseed oil increased with storage time, and the discriminant function first score (DF1) moved from a positive position to a negative position as storage time increased. Changes in DF1 were higher under UV treatment than under the dark condition (DF1: $r^2$=0.9481, F=307.03). The different DF1 values (F1) under the dark condition were 0.099, 0.187, and 0.278 as storage temperature increased. The different values under UV treatment were 0.554, 0.588, and 0.542, as storage temperature increased from 4 to $26^{\circ}C$. As concentrations of prooxidants copper ion and cytochrome C increased, amounts of volatile components also increased. These were confirmed by DFA. Furthermore, changes in responses at each ion fragment agreed with reported results for GC/MS, which formed after rancidity of the oil, including pentane, pentanal, 1-pentanol, hexanal, n-octane, 2-hexenal, heptanal, 2-heptenal, decane, 2-octenal, undecane, and dodecane.

• Information and Communications Magazine
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• v.27 no.1
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• pp.21-27
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• 2009

IT KOREA 미래전략 '5대 핵심과제'의 전략분야별 주요 이슈와 현재 R&D현장에서 추진 중이거나 추진 예정으로 있는 연구개발 방향과 유망기술에 대해 간략히 살펴보고자 한다. IT융합 부문은 IT와 상호 Win-Win 가능한 자동차 조선 의료 등 비(非)IT산업의 IT융합을 촉진하고, 시스템반도체 스마트SOC Green IT 등을 고도화한다는 전략을 토대로 4개 전략분야에서 23개의 유망기술을 발굴 제시하였다. SW 부문은 IT 분야 중 가장 취약한 것으로 평가되고 있는 SW산업을 하드웨어 인프라 등과 연계하여 세계시장 진출이 가능한 수준으로 동반성장 시킨다는 전략을 기반으로 R&D 연관성이 높은 2개 전략분야에서 11개의 유망기술을 발굴 제시하였다. 주력 IT기기 부문은 반도체 디스플레이 휴대폰 등 이미 세계 시장에서 독자적 위치를 차지하고 있는 하드웨어산업의 글로벌 주도권을 더욱 확고히 한다는 전략에 따라 5개 전략분야에서 유망기술 10개를 발굴 제시하였다. 방송통신 부문은 WiBro DMB 등 세계적 수준의 방송통신기술을 바탕으로 4G 3DTV 등 차세대 방송통신기술의 핵심원천기술을 개발하고, 국제표준을 확보한다는 전략을 기반으로 4개 전략분야에서 유망기술 8개를 발굴 제시하였다. 인터넷 부문은 UBcN 미래인터넷 정보보안 등을 대상으로 하고 있으며, 특히 미래인터넷의 경우, 초기 개발단계부터 핵심원천기술 확보를 목표로 시스코 구글 등과 같은 세계적인 기업들을 배출할 수 있는 여건을 조성한다는 전략에 따라 4개 전략분야에서 유망기술 8개를 발굴 제시하였다.

• Journal of Bio-Environment Control
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• v.22 no.4
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• pp.408-412
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• 2013

This study was carried out to investigate damp injury caused by tomato coir bag culture and prevent that. The tomato variety was used 'Minichal', and tomatoes were grown in greenhouse. The nutrient solution based on Yamazaki Tomato Standard Solution was irrigated from one hour after sunrise to two hour before sunset. The slits for darainage were made in three types; I, L, and bottom slit type. The coir bag of I and L type had six slits of 15cm length, that of bottom slit type had three slits of 15 cm length. The weight of coir bag in 24 hours after saturation was 14.2 kg in I type, 13.8 kg in L type, and 12.8 kg in bottom slit type, but there was not significant difference. The weight of coir bag after one day irrigation was 14.5 kg, 14.2 kg, and 13.3 kg at L, I, and bottm slit type, respectively. This means that the moisture content of coir bag during cultivation was lowest in bottom slit type. The number of adventitious root on stem was 160, 170, and 53 at I, L, and bottom slit type, respectively. The dry weight of root and root length were highest at bottom slit type, compared to other treatment. The marketable yield was highest 26.5 kg/20 plant in bottom slit type. For increasing yield and preventing damp injury, bottom slit type was most effective at U type bed coir bag culture.

• Journal of Bio-Environment Control
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• v.24 no.3
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• pp.153-160
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• 2015

The objectives of this study were to determine optimal length of off-time between irrigation cycles to improve irrigation efficiency using a frequency domain reflectometry (FDR) sensor-automated irrigation (FAI) system for tomato (Solanum lycopersicum L.) cultivation aimed at minimizing effluent from coir substrate hydroponics. For treatments, the 5-minute off-time length between 3-minute run-times (defined as 3R5F), 10-minute off-time length between 3-minute run-times (defined as 3R10F), or 15-minute off-time length between 5-minute run-times (defined as 5R15F) were set. During the 3-minute or 5-minute run-time, a 60mL or 80mL of nutrient solution was irrigated to each plant, respectively. Until 62 days after transplant (DAT) during the autumn to winter cultivation, daily irrigation volume was in the order of 3R5F (858mL) > 5R15F (409mL) > 3R10F (306mL) treatment, and daily drainage ratio was in the order of 3R5F (44%) > 5R15F (23%) > 3R10F (14%). Between 63 and 102 DAT, daily irrigated volume was in the order of 5R15F (888mL) > 3R5F (695mL) > 3R10F (524mL) with the highest drainage ratio, 19% (${\pm}2.6$), at the 5R15F treatment. During the spring to summer cultivation, daily irrigation volume and drainage ratio per plant was higher in the 3R5F treatment than that of the 3R10F treatment. For both cultivations, a higher water use efficiency (WUE) was observed under the 3R10F treatment. Integrated all the data suggest that the optimal off-time length is 10 minutes.