• Title/Summary/Keyword: R-R peaks

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A assessment of multiscale-based peak detection algorithm using MIT/BIH Arrhythmia Database (MIT/BIH 부정맥 데이터베이스를 이용한 다중스케일 기반 피크검출 알고리즘의 검증)

  • Park, Hee-Jung;Lee, Young-Jae;Lee, Jae-Ho;Lim, Min-Gyu;Kim, Kyung-Nam;Kang, Seung-Jin;Lee, Jeong-Whan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.10
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    • pp.1441-1447
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    • 2014
  • A robust new algorithm for R wave detection named for Multiscale-based Peak Detection(MSPD) is assessed in this paper using MIT/BIH Arrhythmia Database. MSPD algorithm is based on a matrix composed of local maximum and find R peaks using result of standard deviation in the matrix. Furthermore, By reducing needless procedure of proposed algorithm, improve algorithm ability to detect R peak efficiently. And algorithm performance is assessed according to detection rates about various arrhythmia database.

Analysis of H3K4me3-ChIP-Seq and RNA-Seq data to understand the putative role of miRNAs and their target genes in breast cancer cell lines

  • Kotipalli, Aneesh;Banerjee, Ruma;Kasibhatla, Sunitha Manjari;Joshi, Rajendra
    • Genomics & Informatics
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    • v.19 no.2
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    • pp.17.1-17.13
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    • 2021
  • Breast cancer is one of the leading causes of cancer in women all over the world and accounts for ~25% of newly observed cancers in women. Epigenetic modifications influence differential expression of genes through non-coding RNA and play a crucial role in cancer regulation. In the present study, epigenetic regulation of gene expression by in-silico analysis of histone modifications using chromatin immunoprecipitation sequencing (ChIP-Seq) has been carried out. Histone modification data of H3K4me3 from one normal-like and four breast cancer cell lines were used to predict miRNA expression at the promoter level. Predicted miRNA promoters (based on ChIP-Seq) were used as a probe to identify gene targets. Five triple-negative breast cancer (TNBC)-specific miRNAs (miR153-1, miR4767, miR4487, miR6720, and miR-LET7I) were identified and corresponding 13 gene targets were predicted. Eight miRNA promoter peaks were predicted to be differentially expressed in at least three breast cancer cell lines (miR4512, miR6791, miR330, miR3180-3, miR6080, miR5787, miR6733, and miR3613). A total of 44 gene targets were identified based on the 3'-untranslated regions of downregulated mRNA genes that contain putative binding targets to these eight miRNAs. These include 17 and 15 genes in luminal-A type and TNBC respectively, that have been reported to be associated with breast cancer regulation. Of the remaining 12 genes, seven (A4GALT, C2ORF74, HRCT1, ZC4H2, ZNF512, ZNF655, and ZNF608) show similar relative expression profiles in large patient samples and other breast cancer cell lines thereby giving insight into predicted role of H3K4me3 mediated gene regulation via the miRNA-mRNA axis.

Fabrication and Characterization of Silver-Coated Titanium Dioxide Nanoparticles for a Conductive Paste (은이 코팅된 이산화티탄 나노입자 및 도전성 페이스트 제조 특성)

  • Sim, Sang-Bo;Lee, Mi Chae;Bae, Dong-Sik
    • Korean Journal of Materials Research
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    • v.25 no.12
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    • pp.683-689
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    • 2015
  • In this study, the properties of Ag-coated $TiO_2$ nanoparticles were observed, while varying the molar ratio of water and $Ag^+$ for the surfactant and $TiO_2$. According to the XRD results, each nanoparticle showed a distinctive diffraction pattern. The intensity of the respective peaks and the sizes of the nanoparticles increased in the order of AT1($R_1=5$)(33.3 nm), AT2($R_1=10$)(38.1 nm), AT3($R_1=20$)(45.7 nm), AT4($R_1=40$)(48.6 nm) as well as AT5($R_2=0.2$, $R_3=0.5$)(41.4 nm), AT6($R_2=0.3$, $R_3=1$)(45.1 nm), AT7($R_2=0.5$, $R_3=1.5$)(49.3 nm), AT8($R_2=0.7$, $R_3=2$)(57.2 nm), which values were consistent with the results of the UV-Vis. spectrum. The surface resistance of the conductive pastes fabricated using the prepared Ag-coated $TiO_2$ nanoparticles exhibited a range 7.0~9.0($274{\sim}328{\mu}{\Omega}/cm^2$) times that of pure silver paste(ATP)($52{\mu}{\Omega}/cm^2$).

Analysis of the Pigment Contents of Commercial Indigo Powders and Their Effect on the Color and the Antimicrobial Function of Dyed Cotton Fabrics (시판 쪽 분말염료의 색소 함량에 따른 면직물의 색상 및 항균성 비교연구)

  • Oh, Jeeeun;Ahn, Cheunsoon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.37 no.1
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    • pp.17-26
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    • 2013
  • Market available fermented indigo powders of Indian origin (FI1, FI2), Chinese origin (FC1, FC2), and raw indigo powders of Indian origin (R1, R2) were examined using TLC and HPLC analyses to investigate their pigment contents. TLC analysis gave $R_f$ values of 0.81 and 0.72 for blue and red pigments, respectively. All the powder products and the synthetic and natural indigo standards eluted at 6.9 min and 8.3 min in the HPLC chromatograms, and the peaks showed the ${\lambda}_{max}$ at 610nm and 542nm, representing indigotin and indirubin, respectively. The pigment content calculated based on the area of indigotin and indirubin peaks in the HPLC chromatograms showed that the indigotin content was higher in FC1 and FC2, while FI1 and FI2 had a higher indirubin content. The relative percentage of indirubin was the highest in R2, but the HPLC peak intensity was quite low. Despite the higher indigotin content in FC1 and FC2, cotton dyed with FI1 and FI2 (versus cotton dyed with FC1 and FC2) showed a higher blue (B) hue, the highest K/S values, and the highest antimicrobial effect.

Gas Production of Chemical Leavening Agents and Effects on Textures of Cookies (화학 팽창제의 가스 발생과 쿠키의 텍스쳐 비교)

  • Yang, Seong-Yeon;Kim, Sang-Yong;Jang, Kyu-Seob;Oh, Deok-Kun
    • Korean Journal of Food Science and Technology
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    • v.29 no.6
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    • pp.1131-1137
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    • 1997
  • The production rates of leavening gases and textures of cookies were investigated with various chemical leavening agents(baking powders). The chemical leavening agents could be divided into three group of a fast-acting group such as potassium bicarbonate, tartaric acid, aluminium ammonium sulfate, and fumaric acid, a slow-acting group such as ammonium bicarbonate, sodium bicarbonate, $glucono-{\delta}-lactone$, and ammonium chloride. and a double-acting group such as anhydro monocalcium phosphate, disodium dihydrogenpyrophosphate, and aluminium potassium sulfate according to the different production rate of gases. The leavening rate of ammonium bicarbonate, which was the highest of all leavening agents used in this experiment, was 131.25%. But its after-taste in a cookie was not good due to the residual ammonia. $Glucono-{\delta}-lactone$ only had no after-taste. The higher leavening rate, the more peaks in texture profile graph. Ammonium bicarbonate showed the most peaks in this experiment. It was found that the number of peak had correlation with brittleness of cookies $(r^2=0.8176)$ and brittleness of cookies was different as to various chemical leavening agents.

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Unusual Waveform Detection Algorithm in Arrhythmia ECG Signal (부정맥 심전도 신호에서 특이 파형 검출)

  • Park, Kil-Houm;Kim, Jin-Sub;Ryu, Chunha;Choi, Byung-Jae;Kim, Jungjoon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.23 no.4
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    • pp.292-297
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    • 2013
  • In this paper, unusual waveform detection algorithm based on Refractory Period in arrhythmia ECG signal is proposed. Most of arrhythmia ECG signals consist of unusual waveforms with average 10% rate. Thus tremendous benefit can be obtained in terms of time and cost by providing unusual waveform samples reduced more than 90% to medical staffs who have to monitor and analyze for a long time. The proposed algorithm detects the R-peak using the features of R wave and variable refractory period. For the detected R-peak, unusual waveforms are found using means and standard deviation of electric potential and kurtosis of the R-peaks which are not included in unusual waveform. The proposed algorithm was applied to all records of the MIT-BIH arrhythmia database and showed more than average 90% of compression ratio.

Seasonal Volume Transport Variation and Origin of the Tsushima Warm Current

  • You, Sung-Hyup;Yoon, Jong-Hwan
    • Ocean and Polar Research
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    • v.30 no.2
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    • pp.193-205
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    • 2008
  • A model of the current and seasonal volume transport in the East China Sea was used to investigate the origin of the Tsushima Warm Current (TSWC). The modeled volume transport field suggested that the current field west of Kyushu ($30^{\circ}-32^{\circ}N$) was divided into two regions, R1 and R2, according to the bottom depth. R1 consisted of the Taiwan Warm Current (TWWC) region and the mixed Kuroshio-TWWC (MKT) water region, while R2 was the modified Kuroshio water (MKW) region west of Kyushu. The MKW branched from the Kuroshio and flowed into the Korea/Tsushima Straits through the Cheju-Kyushu Strait, contributing 41% of the annual mean volume transport of the TSWC. The TWWC and MKT water flowed into the Korea/Tsushima Straits through the Cheju-Kyushu and Cheju Straits, contributing 32% and 27% of the volume transport, respectively. The maximum volume transport of the MKW was 53% of the total volume transport of the TSWC in November, while the maximum volume transport of the water in the R1 region through the Cheju-Kyushu Strait was 41% in July. Hence, there were two peaks per year of volume transport in the TSWC.

Correlation between Physicochemical Properties and Peeling Ratio of Korean Chestnut (밤 내피 및 외피의 이화학적 특성 및 박피율과의 상관분석)

  • Hwang, Ja-Young
    • Korean journal of food and cookery science
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    • v.33 no.2
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    • pp.190-197
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    • 2017
  • Purpose: The purpose of this paper was to analyze the physicochemical properties related to peeling rate of Korean chestnut. Methods: Analyses were carried out for weight, thickness, polyphenol, amino acid and peeling ratio for Korean chestnut. The correlation between these physicochemical components and peeling ratio of chestnut was measured. Results: The average of thickness for inner shell and outer shell was 0.66 mm and 0.93 mm, respectively. The average peeling ratio was 77.51%. A significant negative correlation was found between peeling ratio and thickness of the inner shell ($r=-0.80^{***}$, p<0.001). Analysis for the polyphenol composition of inner shell by HPLC was carried out and peaks 2 ($r=-0.56^*$, p<0.05), 11 ($r=-0.68^{**}$, p<0.01), 14 ($r=-0.52^*$, p<0.05), 28 ($r=-0.66^{**}$, p<0.01) showed a significant negative correlation with the peeling ratio. Conclusion: Thickness of chestnut inner shell was determined as the most influential factors of peeling.

Effects of Mo Content on Surface Characteristics of Dental Ni-Ti Alloys (치과용 Ni-Ti합금의 표면특성에 미치는 Mo함량의 영향)

  • Han-Cheol Choe;Jae-Un Kim;Sun-Kyun ark
    • Corrosion Science and Technology
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    • v.22 no.1
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    • pp.64-72
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    • 2023
  • Ni-Ti shape memory alloy for dental nerve treatment devices was prepared by adding Mo to Ni-Ti alloy to improve flexibility and fatigue fracture characteristics and simultaneously increase corrosion resistance. Surface properties of the alloy were evaluated. Microstructure analysis of the Ni-Ti-xMo alloy revealed that the amount of needle-like structure increased with increasing Mo content. The shape of the precipitate showed a pattern in which a long needle-like structure gradually disappeared and changed into a small spherical shape. As a result of XRD analysis of the Ni-Ti-xMo alloy, R-phase structure appeared as Mo was added. R-phase and B2 structure were mainly observed. As a result of DSC analysis, phase transformation of the Ti-Ni-Mo alloy showed a two-step phase change of B2-R-B19' transformation with two exothermic peaks and one endothermic peak. As Mo content increased, R-phase formation temperature gradually decreased. As a result of measuring surface hardness of the Ti-Ni-Mo alloy, change in hardness value due to the phase change tended to decrease with increasing Mo content. As a result of the corrosion test, the corrosion potential and pitting potential increased while the current density tended to decrease with increasing Mo content.

Population Dynamics of Predator (Asplanchna spp.) and its Impact on Herbivorous Rotifers Community in Three Tributaries of the Nakdong River (S. Korea) (낙동강(한국)의 세 지류에서 포식 윤충류 개체군 동태 및 초식 윤충류 군집에 미치는 영향)

  • Kim, Hyun-Woo;Chang, Kwang-Hyeon;Shin, Woon-Kyun;La, Geung-Hwan;Jeong, Kwang-Seuk;Joo, Gea-Jae
    • Korean Journal of Ecology and Environment
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    • v.37 no.4 s.109
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    • pp.385-393
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    • 2004
  • The herbivorous rotifers community (Brachionus spp.) and population dynamics of the predator rotifer (Asplanchna spp.) in three tributaries (Kumho R., Nam R., and Hwang R.) of the Nakdong River were evaluated on biweekly intervals from Jan. 2001 and Dec. 2002. High abundance of the herbivorous rotifers (peak density: - ca.>1000 Ind. $L^{-1}$) was observed from two tributaries (Kumho R. and Nam R.) during the spring and fall seasons, respectively. The high peaks of herbivorous rotifers were not evident in one tributary (Hwang R.). Among the herbivorous rotifers, brachionid rotifers (Brachionus spp. consisting of 7 species) were the characteristic rotifer community in this study. Brachionus spp. tended to occur together with the other perennial species, Asplanchna. Asplanchna was also present while two species of B. angularis and B. calyciflorus were highest in density. Subsequently, two populations (B. angularis and B. calyciflorus) rapidly declined, becoming rare after high peaks of Asplanchna occurred, except in one tributary (Hwang R.). We found community shifts in rotifer groups in mid-spring and mid-fall at the study site. The Asplanchna population could be appeared to play an important role in regulating the rotifer community and total plankton biomass in spring and fall at high trophic levels.