• Title/Summary/Keyword: R곡선

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Applying Aqueous Two Phase Systems to Multi-layer Cosmetics (다중 층 화장료에서 수성 이상계의 응용)

  • Hong, Junki;You, Jaewon;Yoo, Jangyung;Nam, Seungok;Lee, Sanggil;Pyo, Hyeongbae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.2
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    • pp.83-88
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    • 2013
  • The aqueous two phase system has biocompatibility, because it is physically separated into an immiscible liquid multi-layer induced by incompatibility among hydrophilic components dissolved in the water phase. we have applied this principle to aqueous multi-layer liquid cosmetics and select two representative systems. What it was experimentally obtained was the phase diagrams including a binodal curve, a critical point, tie lines of concentration and tie curves of phase separating volume ratio and phase separating time. From the phase diagrams, we were able to observe existence of the optimum condition to prepare the aqueous multi-layer cosmetics for the systems.

Development of machine learning framework to inverse-track a contaminant source of hazardous chemicals in rivers (하천에 유입된 유해화학물질의 역추적을 위한 기계학습 프레임워크 개발)

  • Kwon, Siyoon;Seo, Il Won
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.112-112
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    • 2020
  • 하천에서 유해화학물질 유입 사고 발생 시 수환경 피해를 최소화하기 위해 신속한 초기 대응이 필요하다. 따라서, 본 연구에서는 수환경 화학사고 대응 시스템 구축을 위해 하천 실시간 모니터링 지점에서 관측된 유해화학물질의 농도 자료를 이용하여 발생원의 유입 지점과 유입량을 역추적하는 프레임워크를 개발하였다. 본 연구에서 제시하는 프레임워크는 첫 번째로 하천 저장대 모형(Transient Storage Zone Model; TSM)과 HEC-RAS 모형을 이용하여 다양한 유량의 수리 조건에서 화학사고 시나리오를 생성하는 단계, 두번째로 생성된 시나리오의 유입 지점과 유입량에 대한 시간-농도 곡선 (BreakThrough Curve; BTC)을 21개의 곡선특징 (BTC feature)으로 추출하는 단계, 최종적으로 재귀적 특징 선택법(Recursive Feature Elimination; RFE)을 이용하여 의사결정나무 모형, 랜덤포레스트 모형, Xgboost 모형, 선형 서포트 벡터 머신, 커널 서포트 벡터 머신 그리고 Ridge 모형에 대한 모형별 주요 특징을 학습하고 성능을 비교하여 각각 유입 위치와 유입 질량 예측에 대한 최적 모형 및 특징 조합을 제시하는 단계로 구축하였다. 또한, 현장 적용성 제고를 위해 시간-농도 곡선을 2가지 경우 (Whole BTC와 Fractured BTC)로 가정하여 기계학습 모형을 학습시켜 모의결과를 비교하였다. 제시된 프레임워크의 검증을 위해서 낙동강 지류인 감천에 적용하여 모형을 구축하고 시나리오 자료 기반 검증과 Rhodamine WT를 이용한 추적자 실험자료를 이용한 검증을 수행하였다. 기계학습 모형들의 비교 검증 결과, 각 모형은 가중항 기반과 불순도 감소량 기반 특징 중요도 산출 방식에 따라 주요 특징이 상이하게 산출되었으며, 전체 시간-농도 곡선 (WBTC)과 부분 시간-농도 곡선 (FBTC)별 최적 모형도 다르게 산출되었다. 유입 위치 정확도 및 유입 질량 예측에 대한 R2는 대부분의 모형이 90% 이상의 우수한 결과를 나타냈다.

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The Measurement of Sensitivity and Comparative Analysis of Simplified Quantitation Methods to Measure Dopamine Transporters Using [I-123]IPT Pharmacokinetic Computer Simulations ([I-123]IPT 약역학 컴퓨터시뮬레이션을 이용한 민감도 측정 및 간편화된 운반체 정량분석 방법들의 비교분석 연구)

  • Son, Hye-Kyung;Nha, Sang-Kyun;Lee, Hee-Kyung;Kim, Hee-Joung
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.1
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    • pp.19-29
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    • 1997
  • Recently, [I-123]IPT SPECT has been used for early diagnosis of Parkinson's patients(PP) by imaging dopamine transporters. The dynamic time activity curves in basal ganglia(BG) and occipital cortex(OCC) without blood samples were obtained for 2 hours. These data were then used to measure dopamine transporters by operationally defined ratio methods of (BG-OCC)/OCC at 2 hrs, binding potential $R_v=k_3/k_4$ using graphic method or $R_A$= (ABBG-ABOCC)/ABOCC for 2 hrs, where ABBG represents accumulated binding activity in basal ganglia(${\int}^{120min}_0$ BG(t)dt) and ABOCC represents accumulated binding activity in occipital cortex(${\int}^{120min}_0$ OCC(t)dt). The purpose of this study was to examine the IPT pharmacokinetics and investigate the usefulness of simplified methods of (BG-OCC)/OCC, $R_A$, and $R_v$ which are often assumed that these values reflect the true values of $k_3/k_4$. The rate constants $K_1,\;k_2\;k_3$ and $k_4$ to be used for simulations were derived using [I-123]IPT SPECT and aterialized blood data with a standard three compartmental model. The sensitivities and time activity curves in BG and OCC were computed by changing $K_l$ and $k_3$(only BG) for every 5min over 2 hours. The values (BG-OCC)/OCC, $R_A$, and $R_v$ were then computed from the time activity curves and the linear regression analysis was used to measure the accuracies of these methods. The late constants $K_l,\;k_2\;k_3\;k_4$ at BG and OCC were $1.26{\pm}5.41%,\;0.044{\pm}19.58%,\;0.031{\pm}24.36%,\;0.008{\pm}22.78%$ and $1.36{\pm}4.76%,\;0.170{\pm}6.89%,\;0.007{\pm}23.89%,\;0.007{\pm}45.09%$, respectively. The Sensitivities for ((${\Delta}S/S$)/(${\Delta}k_3/k_3$)) and ((${\Delta}S/S$)/(${\Delta}K_l/K_l$)) at 30min and 120min were measured as (0.19, 0.50) and (0.61, 0,23), respectively. The correlation coefficients and slopes of ((BG-OCC)/OCC, $R_A$, and $R_v$) with $k_3/k_4$ were (0.98, 1.00, 0.99) and (1.76, 0.47, 1.25), respectively. These simulation results indicate that a late [I-123]IPT SPECT image may represent the distribution of the dopamine transporters. Good correlations were shown between (3G-OCC)/OCC, $R_A$ or $R_v$ and true $k_3/k_4$, although the slopes between them were not unity. Pharmacokinetic computer simulations may be a very useful technique in studying dopamine transporter systems.

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RADIOPACITY COMPARISON OF TOOTH COLORED RESTORATIVE MATERIALS WITH DIGITAL RADIOGRAPHY (디지털 방사선사진술을 이용한 치아색 수복물의 방사선불투과도 비교)

  • Kim, Hyo-Jung;Kim, Sung-Kyo
    • Restorative Dentistry and Endodontics
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    • v.25 no.4
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    • pp.499-508
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    • 2000
  • The purposes of this study were to evaluate the validity of 2 kinds of digital radiography techniques in evaluating the radiopacity comparison of restorative materials and to determine the relative radiopacities of several kinds of compomer and flow able resin using these techniques. After taking radiographs of an aluminum step wedge, con-elation of optical density calibration curves were evaluated between conventional radiography with transmission densitometer and CD-Dent digital radiography (storage phosphor system) and between conventional one and RVG$^{(R)}$ digital radiography (CCD system). Compomers such as Dyract$^{(R)}$ AP, Compoglass$^{(R)}$, and Dyract flow$^{(R)}$, and flowable resins such as Ultraseal-XT$^{(R)}$ plus$^{TM}$, Revolution$^{TM}$, Aeliteflo$^{TM}$ and Tetric-flow$^{(R)}$ were used. Five specimens of 5mm in diameter and 2 mm thick were fabricated with each material. Radiopacities of the materials were measured using the above radiographic techniques and compared. The results were as follows: 1. When the optical density calibration curves were compared, conventional radiography and both CD-Dent and RVG$^{(R)}$ digital radiographies showed very high inverse correlations (${\gamma}$=-0.95, ${\gamma}$=-0.98 ; p<0.05). 2. All the tested restorative materials showed levels of radiopacity the same as or greater than that of dentin (p<0.05), Radiopacities of Dyract$^{(R)}$ AP, Compoglass$^{(R)}$, and Tetric flow$^{(R)}$ were greater than those of Revolution$^{TM}$, Aeliteflo$^{TM}$, or dentin (p<0.05). 3. Radiopacities of Dyract$^{(R)}$ AP, Compoglass$^{(R)}$, and Tetric flow$^{(R)}$ were shown to be greater than that of enamel when conventional radiography and CD-Dent digital radiography were used (p<0.05). Radiopacity of Dyract flow$^{(R)}$ was shown to be greater than that of Enamel when conventional radiography was used (p<0.05).

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Evaluation on J-R Curve of 5083 aluminum Alloy Weldment by Load Ratio analysis (Load Ratio 해석에 의한 Al 5083 알루미늄합금 용접부의 J-R곡선 평가)

  • 윤한기;김연겸;우대호
    • Proceedings of the KWS Conference
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    • 1997.05a
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    • pp.91-98
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    • 1997
  • This research is to evaluate of the J-R curve characteristic in 5083 aluminum alloy weldment by utilizing the load ratio analysis. This analysis method can be evaluated the J-R curve only with load-displacement curve without any particular precision instrument equipment in CT specimen. For validity, the results of the load ratio analysis are compared with the those of the J-R curve, which are obtained by the ASTM standard unloading compliance method. The calculated crack length of the load ratio analysis is well appropriate that the measured final crack length. And the J-R curve slope estimated by the load ratio analysis is slightly smaller than that by the ASTM unloading compliance method.

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Experimental Analysis of Wheel Radiation Noise of HANVIT 200 Train in Curve Lines (곡선부에서의 한빛 200 열차 차륜방사 소음 특성)

  • Lee, Chan-Woo;Kim, Jae-Chul
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.907-910
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    • 2008
  • The wheel radiation noise characteristic of Korean tilting train(Hanvit 200) on curved rail under the field test conditions is analyzed in this paper. The test railroad track was selected from Seodaejon to Songjeongri in Honam line. $5^{th}$ and $6^{th}$ car are decided to measure radiation noise level among a train of six cars. The test subject curve radius executed from R400, R500, R600, R700 and R800 segments. The speed of test trains when from R600 and R800 curves existing operation speed and speed up 20% of existing speed. On curved rail at the time of operation speed of Hanvit 200 trains from below 95km/h wheel radiation noise level at $94dBA{\sim}99dBA$, the operation speed from between $100km/h{\sim}144km/h$ wheel radiation noise level at $100dBA{\sim}106dBA$.

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A Study on the Evaluation of 3D Dose Distribution using Normoxic Polymer Gel (정상산소 중합체 겔 선량계를 이용한 3차원 방사선량 평가에 관한 연구)

  • Chung, Se-Young;Kim, Young-Bum;Kwon, Young-Ho;Lee, Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.19 no.1
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    • pp.7-17
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    • 2007
  • Purpose: As increasing complexity of modern radiotherapy technique, more developing dosimetry is required. Polymer gel dosimeters offer a wide range of potential applications with high resolution and assured quality in the thee-dimensional verification of complex dose distribution such as intensity-modulated radiotherapy (IMRT). The purpose of this study is to find the most sensitive and suitable gel as a dosimeter by varying its composition ratio and its condition such as temperature during manufacturing. Materials and Methods: Each polymer gel with various ratio of composition was irradiated with the same amount of photon beam accordingly. Various polymer gels were analyzed and compared using a dedicated software written in visual C++ which converts TE images to R2 map images. Their sensitivities to the photon beam depending on their composition ratio were investigated. Results: There is no dependence on beam energy nor dose rate, and calibration curve is linear. Conclusion: The polymer gel dosimeter developed by using anti-oxidant in this study proved to be suitable for dosimetry.

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Fluid Drag of a Trawl Net and Otter Board Spread in a Midwater Trawl (중층트롤 어구의 그물저항과 전개판 간격)

  • PARK Hae-Hoon;YOON Gab-Dong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.34 no.3
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    • pp.238-244
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    • 2001
  • A method of estimating the fluid drag of a fishing gear and otter board spread in a midwater trawl on full scale was described by implementing a three-dimensional semi-analytic treatment of the towing cable (warp) of a trawl system with the field experiments obtained with the SCANMAR system. The shape of hand rope, bridle and float(or ground) rope attached behind otter boards in a horizontal plane was assumed to be of form $y_r=Ax_r^B$. The distance between otter boards (otter board spread) obtained by the three dimensional analysis of a towing cable must be equal to that obtained by the functional equation of the shape of ropes behind otter boards, The angle of attack of ropes which can be obtained from the functional equation enables one to estimate the fluid drag of trawl net (net drag) by subtracting the fluid drag of the hand rope and bridles from the drag component of the tension of hand rope attached just behind the otter boards.

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Standard Curve Validation using Trendlines in Excel (Excel의 추세선을 이용한 표준곡선 검증)

  • Lee, Kyung-Hwa;Park, Hyung-Ki;Shin, Young-Man
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.2
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    • pp.69-74
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    • 2016
  • Purpose Using a regression formula of the trendline near the coefficient of determination (R2) "1" by substituting the dependent variable of the standard curve to calculate the values of the independent variable. To determine the suitability of a regression equation by comparing the difference between the independent variables of the standard curve and the predicted independent variables. Materials and Methods Perkin Elmer Gamma-Counter machine was used for Standard curve of regression methods. TSH. TG-Ag (Thyroglobulin Antigen), Insulin that used materials and method test to compare the result from the Excel trendline of the regression formula. Results Each of the value of coefficient of determination ($R^2$) and Trendline $R^2=1$, Polynomial Trendline for TSH, $R^2=1$, Polynomial Trendline for TG-Ag, $R^2=0.9994$, Polynomial Trendline for Insulin. Conclusion We confirmed that IRMA immune method is found to the nearest trends elected a standard curve using polynomial trendline. The independent variables to predict the trend by using a polynomial trendline formula containing the error was a limitation.

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The Relationship between the Storage Humidity and the Sorption Rate of Red-Pepper Powder (고춧가루의 저장습도(貯藏濕度)와 흡습속도(吸濕速度)와의 관계(關係))

  • Chun, Jae-Kun;Suh, Chung-Sik
    • Applied Biological Chemistry
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    • v.23 no.1
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    • pp.1-6
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    • 1980
  • The sorption characteristics of red pepper powder were analyzed in respect to its storing humidities and the types of powder product. The sorption rate of the powder was affected by the humidity values under which it was stored. At low relative humidity values below 70% RH the sorption equilibrium was easily attained, but at the higher humidity over 75% RH the equilibrium state was not reached even after a long period of storage. From the estimation of the sorption rate at arbitrary humidity an empirical equation was obtained; In ${\frac{dw}{dt}}=n\;ln(t)+ln\;c$, where w is moisture content(%) absorbed, t is time (hour) and n and c are empirical constants which were determined from empirical data. Particle sizes and drying methods of red pepper showed little effect on the sorption behavior.

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