• Title/Summary/Keyword: R&D3.0

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Preliminary Test of 3D Printed Plastic Scintillators for Proton Beam (3D 프린팅 플라스틱 섬광체의 양성자 빔에 대한 적용)

  • Sung-Hwan, Kim
    • Journal of the Korean Society of Radiology
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    • v.16 no.6
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    • pp.681-686
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    • 2022
  • In this study, a scintillation resin for 3D printing was fabricated with 1.0 wt% of PPO organic scintillator, 5.0 wt% of MMA, and commercial acrylic resin. Using the scintillation resin, 3D-shaped plastic scintillator radiation sensors were successfully fabricated quickly and inexpensively with a commercial 3D DLP printer. The 3D printed plastic scintillator has a good dose-output linearity of R-square 0.998 was obtained in the range of 1 to 10 nA of beam current of the 45 MeV proton beam. The developed 3D plastic scintillator has low light output, so there is a limit to its use in low-dose-rate gamma-ray or X-ray dosimetry. However, it was confirmed that the tissue equivalent material could be usefully used for measuring high energy or high dose rates radiation, such as proton beams and ultra-high dose rate beams.

Investigation on the Amount of Water Evaporation from Composting Facilities Operated in Swine Farms (양돈농가에서 퇴비화시설별 수분변화량 분석에 관한 연구)

  • Kwag, J.H.;Choi, D.Y.;Park, C.H.;Jeong, J.H.;Kim, J.H.;Yoo, Y.H.;Jeon, B.S.;Ra, C.S.
    • Journal of Animal Environmental Science
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    • v.14 no.3
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    • pp.193-200
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    • 2008
  • The results of the research on the amount of water evaporation from composting facilities operated in swine farms are below. The number of swine per a farm was 1433 head/farm for a Simple Composting Facility (SCF) and 3500 head/farm for a Escalator composting facility(ECF) system. The capacities of the SCF and the ECF were $0.33m^3/head$ and $0.25m^3/head$, respectively. The ECF had 24.2% less capacity than the SCF. The average water contents in the swine manure for the CP and the ECF of the surveyed farms were 86.8% and 85.7%, respectively, which revealed the ECF had 1.3% less average water content than the SCF. Daily water inputs into the SCF and the ECF were $4.1kg/m^3/day$ and $6.5kg/m^3/day$, respectively. The ECF had approximately 36.9% higher water input than the SCF. Fermentation temperatures during the composting period for the SCF and the ECF were up to $45^{\circ}C$ and $70^{\circ}C$, respectively. The decreases in water contents per each square meter for the SCF and the ECF were 3.7 kg and 5.2 kg, respectively. The ECF lost approximately 28.8% more water content than the ECF, which would be caused by the difference of fermentation temperature between two systems. Fertilizer components after composting were examined. Nitrogen contents of the SCF and the ECF were similar (0.84% and 0.86%, respectively) and ${P_2}{O_5}$ contents were 0.78% and 0.74%, respectively, showing the SCF had slightly higher content than the ECF. However, OM and OM/N did not show the difference between two systems. Hence, efforts to increase composting efficiency with considerations of the water content of swine manure, fermentation temperature, and water evaporation potential should be done when the SCF and the ECF were used in swine farms.

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Seasonal Differences in Outdoor Activity Time and Serum 25-(OH) Vitamin D Status of Korean Young Women (젊은 여성의 계절별 옥외활동시간과 혈청 25-(OH) 비타민 D 영양상태)

  • Yoon, Jin-Sook;Song, Min-Kyoung
    • Korean Journal of Community Nutrition
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    • v.19 no.3
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    • pp.231-240
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    • 2014
  • Objectives: This study was intended to examine the seasonal differences in outdoor activity times and dietary vitamin D intakes, and explicates their relative impact on improving serum 25-(OH) vitamin D status among Korean young women. Methods: A cross-sectional study was conducted with 135 free-living women aged 19-39 years in Daegu-Kyungbook, Korea. We compared the results from 52 women for the summer and 83 women for the winter. Dietary intake of vitamin D was assessed by 24 hour recall method for non-consecutive three days as well as by food frequency method. Daily outdoor activity times were derived from 24 hour physical activity diary. Results: The average dietary intake of vitamin D of the participants by 24 hour recall method was 3.1 ${\mu}g$ during the summer, 3.3 ${\mu}g$ during the winter, showing no significant difference between the two seasons. Times spent on outdoor activities (p < 0.01) in the summer (= $23.8{\pm}23.6$ min) were much longer than that in the winter (= $10.8{\pm}13.4$ min). The serum 25-(OH) vitamin D levels of participants were $17.5{\pm}7.5$ ng/mL in the summer and $13.4{\pm}4.3$ ng/mL in the winter, showing that the latter was significantly lower than that of the former (p<0.001). The serum 25-(OH) vitamin D levels of subjects were positively related to outdoor activities (r=0.315, p<0.05) during the summer, while related to dietary intake (r=0.252, p<0.05) during the winter. Conclusions: In order to improve the current vitamin D status of Korean young women, nutrition education programs should focus on increasing more dietary intake especially during the winter, and performing more outdoor activities in other seasons.

Anthocyanin Production from Culture of Alnus hirsuta Callus (물오리나무 캘러스로부터 Anthocyanin 생산)

  • 안정선
    • Journal of Plant Biology
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    • v.37 no.2
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    • pp.237-244
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    • 1994
  • Callus tissues derived from protoplast of Alnus hirsuta were shown to produce red pigments under the continuous light. The R4 cell line with high yield of the pigments was selected. One of the red pigments was identified as anthocyanin; glucose and galactose as sugar moiety and cyandin as aglycone, by spectroscopic analysis, cellulose TLC and GLC. Both callus growth and anthocyanin accumulation were remarkably stimulated by 2,4-D. The highest anthocyanin yield was observed when $1\;\mu\textrm{M}$ 2,4-D in combination with $0.1\;\mu\textrm{M}$ BAP was supplemented to the culture medium. In case of inorganic salts, anthocyanin yield was enhenced by reducing concentration of phosphate from 5.0 mM to 2.5 mM and by increasing the ratio of ${NO_3}^{-}$ type to 80% for total nitrogen source.source.

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Influence of Sb Addition on Microstructure, Mechanical Properties and Electric Conductivity of Aluminum (알루미늄의 Sb 첨가에 따른 미세조직, 전기전도도 및 기계적 특성 변화)

  • Hyo-Sang, Yoo;Yong-Ho, Kim;Byoung-Kwon, Lee;Eun-Chan, Ko;Seong-Hee, Lee;Sang-Chan, Lee;Hyeon-Taek, Son
    • Korean Journal of Materials Research
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    • v.32 no.11
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    • pp.489-495
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    • 2022
  • This research investigated how adding Sb (0.75, 1.0, 2.0 and 5.0 wt%) to as-extruded aluminum alloys affected their microstructure, mechanical properties, electric and thermal conductivity. The addition of Sb resulted in the formation of AlSb intermetallic compounds. It was observed that intermetallic compounds in the alloys were distributed homogenously in the Al matrix. As the content of Sb increased, the area fraction of intermetallic compounds increased. It can be clearly seen that the intermetallic compounds were crushed into fine particles and homogenously arrayed during the extrusion process. As the Sb content increased, the average grain size decreased remarkably from 282.6 ㎛ (0.75 wt%) to 109.2 ㎛ (5.0 wt%) due to dynamic recrystallization by the dispersed intermetallic compounds in the aluminum matrix during the hot extrusion. As the Sb content increased from 0.75 to 2.0 wt%, the electrical conductivity decreased from 61.0 to 59.8 % of the International Annealed Copper Standard. Also, as the Sb content increased from 0.75 to 2.0 wt%, the ultimate tensile strength did not significantly change, from 67.3 to 67.8 MPa.

Dipeptide (Tyr-Ile) Acting as an Inhibitor of Angiotensin-I-Converting Enzyme (ACE) from the Hydrolysate of Jellyfish Nemopilema nomurai

  • Kim, Yeon-Kye;Lim, Chi-Won;Yeun, So-Mi;Lee, Moon-Hee;Moon, Ho-Sung;Cho, Hyeon-Ah;Yoon, Na-Young;Yoon, Ho-Dong;Park, Hee-Yeon;Lee, Doo-Seog
    • Fisheries and Aquatic Sciences
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    • v.14 no.4
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    • pp.283-288
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    • 2011
  • The jellyfish Nemopilema nomurai was hydrolyzed with papain and a novel dipeptide purified via ultrafiltration, gel filtration chromatography with Sephadex LH-20, and reverse phase chromatography using $C_{18}$ and $C_{12}$ columns. The IR, 1H NMR, 13C NMR, and MS spectrometer analyses showed that the dipeptide comprised tyrosine-isoleucine (Tyr-Ile). The $IC_{50}$ and $K_i$ values were $6.56{\pm}1.12$ and $3.10{\pm}0.28\;{\mu}M$, respectively, indicating competitive inhibition of angiotensin-I-converting enzyme (ACE). As a novel ACE-inhibitory active peptide, Tyr-Ile may have potential for use in antihypertensive therapy.

o-Dihydroxyisoflavone Derivatives from Highly Aged Korean Fermented Soybean Paste by Jang Yang Process and Its Biological Activity (장양(藏釀) 기술이 사용된 전통 고숙성 된장에서 유래한 o-Dihydroxyisoflavone 유도체의 생리활성)

  • Kim, Dong-Hyun;Park, Jun-Seong;Park, Nok-Hyun;Moon, Eun-Jeong;Yu, Sun-Hye;Kim, Duck-Hee;Kim, Han-Kon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.3
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    • pp.203-208
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    • 2009
  • Doenjang (Korean fermented soybean paste) is a unique fermented food in Korea. It has been traditionally manufactured from soybeans, by Jang Yang process. We focused on the newly formed compound in highly aged Doenjang and its biological activity. One new o-dihydroxyisoflavone, 7,3',4'-trihydroxyisoflavone and two known o-dihydroxyisoflavone derivatives were isolated from 5-year-old Doenjang and evaluated as potent antioxidant and whitening effect by comparing with other known isoflavone. 7,8,4'-Trihydroxyisoflavone (compound 1), 7,3',4'-trihydroxyisoflavone (compound 2) and 6,7,4'-trihydroxyisoflavone (compound 3) inhibited DPPH (diphenyl-1-picrylhydrazyl) formation by 50 % at a concentration of $21.5{\pm}0.2$, $28.7{\pm}0.4$ and $32.6{\pm}0.6$ ($IC_{50}$) respectively, whereas daidzein showed weak DPPH radical scavenging activity. In superoxide scavenging effect were measured in one assay. Compound 1 ($IC_{50}=18.10{\pm}0.2{\mu}M$) and 2 ($IC_{50}=10.54{\pm}0.4{\mu}M$) show significant inhibitory activity and greater effect than L-ascorbic acid. But compound 3 and daidzein showed lower inhibition activity. Also, o-dihydroxyisoflavone derivatives evaluated as potent inhibitors on tyrosinase activity and melanin formation in melan-a cells. Compound 1 ($IC_{50}=11.21{\pm}0.2{\mu}M$), compound 2 ($IC_{50}=5.23{\pm}0.6{\mu}M$) exhibited significant inhibitory effect on tyrosinase activity. Furthermore, those compounds are significantly suppressed the cellular melanin formation by 50 % at a concentration of $12.23{\pm}0.7{\mu}M$ (1) and $7.83{\pm}0.7{\mu}M$ (2). This result suggests that 7,3',4'-trihydroxyisoflavone from highly aged Doenjang could be used as an active ingredient for cosmetics.

Measuring Leaf Areas with a Structured-Light 3D Scanner (3차원 구조광 스캐너를 이용한 식물의 잎 면적 측정 방법)

  • Nam, Kyong-Hee;Ko, Eun Mi;Mun, Saeromi;Kim, Chang-Gi
    • Korean Journal of Ecology and Environment
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    • v.47 no.3
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    • pp.232-238
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    • 2014
  • We have developed a non-destructive, touch-free method for estimating leaf areas with a structured-light three-dimensional (3D) scanner. When the surfaces of soybean leaves were analyzed with both the 3D scanner and a leaf area meter, the results were linearly related ($R^2=0.90$). The strong correlation ($R^2=0.98$) was calculated between shoot fresh weights and leaf areas when the scanner was employed during growth stages V1 to V4. We also found that leaf areas measured by the scanner could be used to detect changes in growth responses to abiotic stress. Whereas under control conditions the areas increased over time, salt and drought treatments were associated with reductions in those values after 14 d and 12 d, respectively. Based on our findings, we propose that a structured-light 3D scanner can be used to obtain reliable estimates of leaf area and plant biomass.

Effect of ${\beta}$-Mannanase (CTCZYME$^{(R)}$) on the Growth of Young Calf (${\beta}$-Mannanase (CTCZYME$^{(R)}$) 첨가가 어린 송아지의 성장에 미치는 영향)

  • Lee, Se-Young;Lee, Sang-Moon;Kim, Jong-Hyeong;Ki, Kwang-Seok;Kim, Hyeon-Shup;Kam, Dong-Keun;Lee, Jae-Hwan;Lee, Jung-Jin;Bae, Gui-Seck;Seo, Seong-Won
    • Korean Journal of Agricultural Science
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    • v.37 no.2
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    • pp.239-243
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    • 2010
  • The objective of this study was to evaluate effects of supplementation of ${\beta}$-mannanase (CTCZYME$^{(R)}$, CTCBIO, Inc.) on feed intake, growth performance and fecal health of calves fed two levels (3% vs. 8%) of palm kernel meal (PKM). A total of nine Holstein calves were divided into three groups, and fed a conventional starter containing 3% PKM (CON), CON+0.1% CTCZYME$^{(R)}$ (TRT1), or a starter containing 8% PKM+0.1% CTCZYME$^{(R)}$ (TRT2). No clinical symptom of calves was observed through the trial. We did not find significant differences among the treatments on mean feed intake, growth performance, or fecal health during the four-week experimental period. Feed efficiency tended to be improved by adding CTCZYME$^{(R)}$ (0.46, 0.87 and 0.52 for CON, TRT1 and TRT2, respectively). Compared with CON (921 g/d and 786 g/d), TRT2 had lower feed intake (727 g/d) and average daily gain (ADG, 631 g/d) before weaning. However, feed intake (2300 g/d) and ADG (1012 g/d) were similar or even higher in TRT2 than CON (2269 g/d and 560 g/d) after weaning. This was probably due to the effect of a large amount of mannan-oligosaccharide released from PKM by ${\beta}$-mannanase. Salmonella was not detected any fecal samples. No significant difference was observed in the number of fecal E. coli or fecal properties including color, smell, and watery indexes among the treatments. We conclude that a calf starter containing 8% PKM with 0.1% CTCZYME$^{(R)}$ is comparable with a conventional starter in feed intake and growth performance of calf, which is beneficial in terms of reduction in feed cost.

Analysis of R&D Efficiency between Industries : focusing on Technology-innovative SMEs (연구개발 활동 효율성의 산업간 비교 분석: 기술혁신형 중소기업을 대상으로)

  • Jeon, Soojin
    • Journal of Technology Innovation
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    • v.29 no.3
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    • pp.33-62
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    • 2021
  • This study compares and analyzes the efficiency of R&D activities of technology-innovative small and medium-sized enterprises(SMEs) between industries and proposes ways to improve efficiency. The research samples are 6,708 technology-innovative SMEs, which have received a guarantee by the KIBO from 2008 to 2011. Input variables are the level of R&D personnel, R&D investment, and output variables are patent applications, prototype. Efficiency is measured by the DEA model, and indirect comparisons that are individually measured by industry are performed. As a result of the analysis, the CCR for determining the optimal returns to scale is 0.19, the BCC for determining the optimal input distribution is 0.70, and the SE for determining the optimal output is 0.30. By industry type, the medium and low-tech industries have high CCR and BCC, while the high-end and high-tech industries have high SE. R&D activities need to be operated on an optimal scale through managing R&D performance because there is the inefficiency of scale across the industry. The contribution of the study is to analyze the R&D efficiency of each industry of technology-innovative SMEs by the technology evaluation data of the KIBO.