• Title/Summary/Keyword: R&D program

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A Study on the Control and Exposure Assessment to Vinyl Chloride in the Factory Processing and Producing PVC Resin (일부 PVC 수지 제조 및 가공 근로자의 염화비닐 폭로 평가와 대책에 관한 조사 연구)

  • Park, D.W.;Shin, Y.C.;Lee, N.R.;Lee, K.Y.;Oh, S.M.;Chung, H.K.
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.4 no.1
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    • pp.33-42
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    • 1994
  • This study was carried out to assess worker exposure to vinyl chloride monomer (VCM) and to present control measures in the factories processing and producing polyvinyl chloride (PVC) resin. The conclusion remarks are as follows. Only two personal samples in the factory ("E") processing polyvinyl chloride resin were analysed to be 27.6 ppm and 12.6 ppm, respectively. But, these concentration exceed 1 ppm, Permissible Exposure Limits (PEL) of OSHA. So, worker's exposure to VCM at "E" factory should be reevaluated. In "A", "B" and "C" factory producing polyvinyl chloride resin, the average worker's exposures to VCM were 0.12 ppm, 0.86 ppm and 1.23 ppm, respectivery. Worker exposure to VCM at distillation and dry process was higer than other processes at "A" factory. The average exposure concentration of worker at polymerization process of "B" and "C" factory was 1.23 ppm, and 1.46 ppm respcetively. These concentration exceed 1 ppm, Permissible Exposure Limits of OSHA. Control room of "B" and "C" factory had 0.91 ppm and 0.65 ppm of worker's exposure concentration respectively. "A" factory was evaluated to be "acceptable", but "B" and "C" factories were evaluated to be "not acceptable", by the workplace exposure assessment program of AIHA. Process other than bagging and control room of "A" factory was evaluated to "not acceptable". Immediate correction measures for preventing workers from exposure to VCM should be performed in the factories or process that were evaluated to be "not acceptable". After these control measures are taken, worker exposure to VCM must be reevaluated through personal air monitoring. Control measures presented by this study are complete sealing of connecting pipe lines, flanging, packing, bolting and nutting. Periodic leak test for leak parts is also required. And positive pressure facility should be constructed at control room of "B" and "C" factory. Fresh air through cleaner such as HEPA filter should be supplied to control room. In addition to these control measures, periodic personal monitoring for evaluating worker exposure to VCM should be performed.

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Current Status and Outlook of the Space Economy (우주분야 연구개발 및 산업동향)

  • Choi, Soo-Mi
    • Current Industrial and Technological Trends in Aerospace
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    • v.6 no.1
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    • pp.3-13
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    • 2008
  • The year 2007 marked two important anniversaries for space. The Soviet Union launched Sputnik 50 years ago on October 4. 1957. The 40th anniversary of the United Nations treaty on outer space was also marked in 2007. 2008 and 2007 were full of dramatic events of space activity as well : Success of Japan's first large lunar explorer 'KAGUYA'(SELENE) and China's 'Chang'e 1', launch of ISS laboratory module, 'Colombus' and 'Kibo', test of China's ASAT, and success of Korea's first astronaut program and so on. International government space budgets reached $78.3 billion in 2007, a strong growth rate of 36% over 2006, and the recently released Global Exploration Strategy, The Framework for Coordination is a set of guidelines for international cooperation among 14 of the world's space agencies. Worldwide space industry revenue grew by 20% over 2005, $106.1 billion in 2006 and $173.9 billion expected in 2007. This paper discusses the issues related to the Earth observation R&D trend and market in detail. Korea's 2008 government space spending is \316.4 billion, 2007 space industry revenue was $106 million. Several research projects are now underway and STSAT 2 will be launched by KSLV-1 at the Naro Space Center within this year.

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A Major Locus for Quantitatively Measured Shank Skin Color Traits in Korean Native Chicken

  • Jin, S.;Lee, J.H.;Seo, D.W.;Cahyadi, M.;Choi, N.R.;Heo, K.N.;Jo, C.;Park, H.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.11
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    • pp.1555-1561
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    • 2016
  • Shank skin color of Korean native chicken (KNC) shows large color variations. It varies from white, yellow, green, bluish or grey to black, whilst in the majority of European breeds the shanks are typically yellow-colored. Three shank skin color-related traits (i.e., lightness [$L^*$], redness [$a^*$], and yellowness [$b^*$]) were measured by a spectrophotometer in 585 progeny from 68 nuclear families in the KNC resource population. We performed genome scan linkage analysis to identify loci that affect quantitatively measured shank skin color traits in KNC. All these birds were genotyped with 167 DNA markers located throughout the 26 autosomes. The SOLAR program was used to conduct multipoint variance-component quantitative trait locus (QTL) analyses. We detected a major QTL that affects $b^*$ value (logarithm of odds [LOD] = 47.5, $p=1.60{\times}10^{-49}$) on GGA24 (GGA for Gallus gallus). At the same location, we also detected a QTL that influences $a^*$ value (LOD = 14.2, $p=6.14{\times}10^{-16}$). Additionally, beta-carotene dioxygenase 2 (BCDO2), the obvious positional candidate gene under the linkage peaks on GGA24, was investigated by the two association tests: i.e., measured genotype association (MGA) and quantitative transmission disequilibrium test (QTDT). Significant associations were detected between BCDO2 g.9367 A>C and $a^*$ ($P_{MGA}=1.69{\times}10^{-28}$; $P_{QTDT}=2.40{\times}10^{-25}$). The strongest associations were between BCDO2 g.9367 A>C and $b^*$ ($P_{MGA}=3.56{\times}10^{-66}$; $P_{QTDT}=1.68{\times}10^{-65}$). However, linkage analyses conditional on the single nucleotide polymorphism indicated that other functional variants should exist. Taken together, we demonstrate for the first time the linkage and association between the BCDO2 locus on GGA24 and quantitatively measured shank skin color traits in KNC.

The Effect of Environment-friendly Certifications on Agricultural Producer Organizations (친환경·GAP·HACCP이 농업 생산자조직에 미치는 영향)

  • Kim, Chang-Hwan;Park, Seong-Ho
    • Journal of Distribution Science
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    • v.13 no.6
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    • pp.97-104
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    • 2015
  • Purpose - The distribution of agricultural products is changing due to recent shifts in environmental free trade. Specifically, the competitiveness of domestic agricultural products has weakened as a result of the Korea-China Financial Trade Agreement. Agricultural producers are faced with increasing difficulties and organized production centers are growing in importance daily. To overcome this crisis, agricultural producer organizations are vying for environment-friendly agricultural certifications, Good Agriculture Practices (GAP) and Hazard Analysis and Critical Control Point (HACCP). In particular, as consumer demand for higher safety grows, farmers are increasing their certification rates. Therefore, this certification system is expected to help strengthen the competitiveness of agricultural producer organizations. Research design/data/methodology - Organized production centers are classified by certification. A survey was conducted with 91 organizations using factor analysis and logistic regression analysis for the examination. The factor analysis results are as follows. Raw material procurement, education·specialization, marketing, joint business, organizing ability, business management, effectiveness, certification, and larger organizations were classified as the nine types of factors. These factors affect the organized production centers and are used in the logistic regression analysis. The purpose of such research and analysis is to suggest a direction for future production center policies. Results - The basic statistical results are as follows: analysis of the producer organizations of 91 sites, average number of members per site of 1,624, and average sales of 25,961 million won. Additionally, the average income per farmer is 175 million won, and the pooling system rate is 53.5%. The factor analysis results are as follows. Factor 1 consists of contract cultivation, ongoing shipment, selection subdivision, traceability, and major retailer management. Factor 2 consists of manual cultivation, specialty selection, education program, and R&D. Factor 3 consists of advertising, various dealers, various sales strategies, and a unified sales counter. Factor 4 consists of agricultural materials co-purchase, policy support, co-shipment, and incentives. Factor 5 consists of the co-selection and pooling system. Factor 6 consists of co-branding and operating by the organization's article. Factor 7 consists of the buy-sell ratio and rate of operation of the agriculture promotion center. Factor 8 consists of bargaining power in volume and participation rate of farmer certification. Factor 9 consists of increasing new subscribers. The logistic regression analysis results are as follows. Considering the results by type of certification, the environment-friendly agricultural certification type and the GAP certification type have a (+) influence. GAP and HACCP certification types affecting the education·specialization factor have a (+) influence. Considering the results for each type of certification, the environment-friendly agricultural certification types on the effectiveness factor have (-) influence; the HACCP certification types on the organizing ability and effectiveness factor have a (-) influence. Conclusions - Agricultural producer organizations should develop plans as follows: The organizations need to secure education for agricultural production; increase the pooling system ratio for sustainable organizational development; and, finally, expand the number of agricultural producer organizations.

Influencing Factors on the Duration of Offset Agreement (절충교역 계약 소요기간 영향요인)

  • Hong, Seok-Soo;Joung, Tae-Yun;Seo, Jae-Hyun;Hong, Moon-Hee
    • Journal of Technology Innovation
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    • v.20 no.1
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    • pp.1-15
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    • 2012
  • Republic of Korea has been applying offset to defense acquisition program for some benefits such as modernization of defense industry and enhancement of R&D capabilities since 1983. But in point of implementation, there is the possibility of delay of offset agreements based on the value of proposed technologies. As it often happens that the delay of offset agreement negatively affects the time schedule of main defense deal, it is necessary to prepare for this issue. The purpose of this study is to extract some factors affecting the duration of offset agreement by statistical analysis. Reviewing existing papers and contract process, nationality of enterprise, the number of project participants, properties of project, the number of technologies in the first proposal, level of domestic defense technology in each weapons system, the amount of main contract were used as independent variable and duration of agreement as dependent variable. To hypothesis testing, correlation and multiple regression analysis were conducted using the previous 25 contract cases. As a result of correlation analysis, the amount of main contract, the number of technologies in the first proposal and properties of project have positive relationships with dependent variable. In multiple regression, the amount of main contract and the number of project participants have significant effect on the duration of offset agreement.

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Risk Factors of Work-related Low Back Pain in Manufacturing Workers (제조업 근로자들의 작업과 연관된 요통의 위험요인에 관한 연구)

  • Kim, D.H.;Shin, H.R.;Chun, J.H.;Kim, Y.W.;Kim, J.H.;Lee, C.U.
    • Journal of Preventive Medicine and Public Health
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    • v.26 no.1 s.41
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    • pp.20-36
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    • 1993
  • Work-related low back pain is one of the major factors that cause the loss of working power especially in actively working age, therefore controlling the work-related low back pain is one of the major issues in the field of industrial safety and health. This study was performed for detecting the risk factors and proposing the efficient control program of the work-related low back pain. The subjects were male workers employed at the manufacturing industry in Pusan with longer than 6 months' working duration. The data was collected by self-reported questionnaire and interview from May 1 to October 31,1992. The contents of questionnaire were as follows:. the experience of low back pain within the recent one month, general characteristics(age, marital status, education level, religion, regular exercise), physical characteristics(height, weight), employment status(working duration, daily working hours, rest during work, satis(action fur the job), type of work and working environments(posture, forward bending, lifting and movement, satisfaction for table and chair). The result was analyzed for 608 entire respondents by case-control comparative method. The number of cases was 152 with a history of work-related low back pain, so the relative frequency of self-reported work-related low back pain was 25.0%, and the number of controls was 344 without any history of low back pain. As a result, two characteristics of the employment status(working duration, satisfaction fur the job) and all characteristics of type of work and working environments showed a statistical significance between the case and control groups(p<0.01). The Oddb ratios of these variables for Work-related low back pain were calculated. They were 7.88 for the satisfaction fur chair, 7.86 for lifting and movement,3.31 for satisfaction for table, and 2.22 fur bending forward(p<0.01). And for the multivariate logistic regression analysis confirmed that unsatisfaction for table was independent risk factor for Work-related low back pain. In summary, though this study was based upon the self-reported questionnaire and the subjective complaints, the satisfaction for chair, lifting and movement, satisfaction for table, and bending forward concerned with the type of work and working environments were considered as the main factors causing the work-related low back pain, and the work-related low back pain may be preventable by the ergonomic control of these factors.

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Development of Control System for Kimchi Fermentation and Storage Using Refrigerator (냉장고를 이용한 김치발효 및 저장 제어시스템의 개발)

  • Ko, Yong-Duck;Kim, Heung-Jae;Chun, Sung-Sik;Sung, Nack-Kie
    • Korean Journal of Food Science and Technology
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    • v.26 no.3
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    • pp.199-203
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    • 1994
  • Software for refrigerator capable of both rapid fermentation and suitable storage of Kimchi was developed and its performance was investigated. Refrigerator system consists of an insulated fermentation room, heater, damper for the control of outer cold air and two sensors for recognizing temperature of heater and fermentation room, which control temperature and time period of affecting Kimchi fermentation. Effects of fermentation at different NaCl concentration and three fermentation function keys were studied; At key I, time which was elapsed to edible ripening state, pH 4.5 and total acid 0.6%, was about $3{\sim}4$, $4{\sim}5$ and $11{\sim}12$ days, respectively. At key II, time was about $2{\sim}3$, $3{\sim}4$, and $10{\sim}11$ days, and at key III, about 2, 3 and $9{\sim}10$ days, respectively. Effect of storage at three fermentation function keys was all maintained to the level of a palatable pH range until 14 days. Sensory evaluation of Kimchi showed also significant difference in a taste.

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Development of a Techniques of the Performance Test for a Radiation Protection Devices and it's International Standards (방사선 방호용 계측기 성능평가 기술 개발 및 국제 표준)

  • Choi, Kil-Oung;Won, Sung-Ho;Kim, Jung-Ho;Hah, Suck-Ho;Yi, Chul-Young;Kim, Hyun-Moon;Lee, Min-Kee
    • Journal of Radiation Protection and Research
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    • v.33 no.1
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    • pp.1-12
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    • 2008
  • International Standardization in all technical area is gaining its momentum as its impact and implication over global trade is directly linked. The worldwide competition to secure a dominant position in the standardization process is ever growing over the years. In 2005, the International Technical Committee on Nuclear Instrumentation, which is a subunit of International Electro-technical Commission (IEC), was held in Korea under the auspices of MOST (Ministry of Science and Technology). Korea has adopted its Rule and Regulation as the National Standard. As a part of a link to National Mid-and Long-term Atomic Energy R&D Program of MOST, the technical development of a performance test for the radiation monitors was carried out under mechanical environment and electromagnetic immunity conditions. The characteristics of the radiation fields were also evaluated under the conditions and introduced to a techniques of performance test for the radiation protection instrumentation adopted IEC61526 standards and it's results was analyzed. We would like to share the experience gained in these efforts, failure as well as success, and to discuss the problems encountered and serious consideration to be taken into account in the future endeavor.

Korea Barcode of Life Database System (KBOL)

  • Kim, Sung-Min;Kim, Chang-Bae;Min, Gi-Sik;Suh, Young-Bae;Bhak, Jong;Woo, Tae-Ha;Koo, Hye-Young;Choi, Jun-Kil;Shin, Mann-Kyoon;Jung, Jong-Woo;Song, Kyo-Hong;Ree, Han-Il;Hwang, Ui-Wook;Park, Yung-Chul;Eo, Hae-Seok;Kim, Joo-Pil;Yoon, Seong-Myeong;Rho, Hyun-Soo;Kim, Sa-Heung;Lee, Hang;Min, Mi-Sook
    • Animal cells and systems
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    • v.16 no.1
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    • pp.11-19
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    • 2012
  • A major concern regarding the collection and storage of biodiversity information is the inefficiency of conventional taxonomic approaches in dealing with a large number of species. This inefficiency has increased the demand for automated, rapid, and reliable molecular identification systems and large-scale biological databases. DNA-based taxonomic approaches are now arguably a necessity in biodiversity studies. In particular, DNA barcoding using short DNA sequences provides an effective molecular tool for species identification. We constructed a large-scale database system that holds a collection of 5531 barcode sequences from 2429 Korean species. The Korea Barcode of Life database (KBOL, http://koreabarcode.org) is a web-based database system that is used for compiling a high volume of DNA barcode data and identifying unknown biological specimens. With the KBOL system, users can not only link DNA barcodes and biological information but can also undertake conservation activities, including environmental management, monitoring, and detecting significant organisms.

Meta- and Gene Set Analysis of Stomach Cancer Gene Expression Data

  • Kim, Seon-Young;Kim, Jeong-Hwan;Lee, Heun-Sik;Noh, Seung-Moo;Song, Kyu-Sang;Cho, June-Sik;Jeong, Hyun-Yong;Kim, Woo Ho;Yeom, Young-Il;Kim, Nam-Soon;Kim, Sangsoo;Yoo, Hyang-Sook;Kim, Yong Sung
    • Molecules and Cells
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    • v.24 no.2
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    • pp.200-209
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    • 2007
  • We generated gene expression data from the tissues of 50 gastric cancer patients, and applied meta-analysis and gene set analysis to this data and three other stomach cancer gene expression data sets to define the gene expression changes in gastric tumors. By meta-analysis we identified genes consistently changed in gastric carcinomas, while gene set analysis revealed consistently changed biological themes. Genes and gene sets involved in digestion, fatty acid metabolism, and ion transport were consistently down-regulated in gastric carcinomas, while those involved in cellular proliferation, cell cycle, and DNA replication were consistently up-regulated. We also found significant differences between the genes and gene sets expressed in diffuse and intestinal type gastric carcinoma. By gene set analysis of cytogenetic bands, we identified many chromosomal regions with possible gross chromosomal changes (amplifications or deletions). Similar analysis of transcription factor binding sites (TFBSs), revealed transcription factors that may have caused the observed gene expression changes in gastric carcinomas, and we confirmed the overexpression of one of these, E2F1, in many gastric carcinomas by tissue array and immunohistochemistry. We have incorporated the results of our meta- and gene set analyses into a web accessible database (http://human-genome.kribb.re.kr/stomach/).